Yu dɔn gɛt dis prɔblɛm bak wit yu bren blɔd vesel dɛn? (Cerebral Amyloid Angiopathy - CAA) Lɛ wi tɔk bɔt dis!

Sɔntɛnde, wi kin fil diziz smɔl, nɔto so? Ɔ i tan lɛk se wi mɛmori wik smɔl. Sɔm pipul dɛn kin tink se dis na nɔmal tin we kin apin as wi de ol. Bɔt, sɔntɛnde dis kin dip smɔl pas dat. Tide wi go tok abaut somtin laik dis. dat min se, bכt wan kכndyushכn we dεn kכl `(Sεribral Amyloid Angiopathy)` כ `(CAA)`.

Wetin na `(Sεribral Amyloid Angiopathy - CAA)`?

Fɔ tɔk am simpul wan, Cerebral Amyloid Angiopathy (CAA) na wan sik we wan abnɔmal prɔtin kin gɛda na di smɔl smɔl blɔd vesel dɛn na wi bren, we kin mek dɛn wik smɔl smɔl ɛn lik blɔd. di men tin we kin mek dis apin na we wan abnכmal protin we dεn kכl amyloid de kכmכt na di wכl dεm na di bכdi vεsul dεm na di bren. Tink bɔt am lɛk se wata paip de lɔk. As tɛm de go, dis amyloid protin de mek di wɔl dɛn na di blɔd vesel dɛn tan, wik, ɛn i izi fɔ pwɛl.

We di blɔd vesel dɛn wik dis kayn we, blɔd kin bigin fɔ lik insay di bren. sכmtεm dεn lik dεm ya kin rili sכm, lεk ``maykroblid'' . Dat min se, smɔl smɔl blɔd dɛn kin fɔdɔm. Dɛn tin ya so smɔl dat sɔmtɛm wi nɔ kin notis ɛni sayn. bכt sכmtεm dis kin go te to ``intracranial hemorrhage'' , dat na big bכdi we de kכmכt insay di bren. If dis blɔd de kɔmɔt, i kin pwɛl di bren tisu ɛn mek i gɛt siriɔs prɔblɛm.

dis kכndyushכn, we dεn kכl ``CAA'', dεn dכn no am bak as di mεjכr kכz fכ wan kכndyushכn we dεn kכ l ``kכgnitiv dεklin'' . ``(Cognitive decline)'' de tכk bכt di dεklin sכmtεm we wi de tink, lεk fכ mεmכri, atεnshכn, rizin, εn di skil dεm fכ sכlv prכblεm. i tan lεk se wi bren in ``prכsesa'' de ``slow dכn.'' Akɔdin to masta sabi pipul dεm, bitwin 23% εn 29% pan pipul dεm we pas 50 ia kin gεt dis ``(CAA)'' kכndyushכn na mכdarεt כ siriכs lεvεl. Dat min se i nɔto so rare.

Wetin na di poshubul simptom dɛm fɔ `(CAA)`?

De sayn dɛm wae kin apun na dis kayn sik nɔr kin bi di sem fɔ ɔlman. I dipen pan aw bɔku blɔd de lik insay di bren.

Tink bɔt se sɔm pipul dɛn kin gɛt ``CAA'' we nɔ gɛt ɛni sayn. di rizin na dat dεn nכ de gεt rili sכm sכm bכdi we dεn nכ de notis na dεn bren (``silent microbleeds''), we dεn nכ de notis. I tan lɛk se wata de lik smɔl smɔl frɔm smɔl ol, bɔt nɔto lik we big fɔ ful-ɔp bɔkit.

Bɔt if bɔku bɔku blɔd de insay di bren, dat min se prɔblɛm dɛn kin apin na di nyurolɔjik. Dɔn bak, sɔm pipul dɛn kin fɛnɔt bɔt ``CAA'' we dɛn gɛt ``MRI'' skan na di bren fɔ sɔm ɔda prɔblɛm.

If di blɔd de kam tranga, sɔm kayn sayn dɛn lɛk dis kin apin:

• Ed we de at bad bad wan: Nɔto nɔmal ed pen, jɔs smɔl smɔl.
• Kɔnfyushɔn : Tin dɛn lɛk ples, tɛm, ɛn udat de arawnd kin kɔnfyus.
• I nɔ izi fɔ tɔk : Fɔ mek yu nɔ tɔk fayn ɛn i nɔ izi fɔ tɔk wetin yu want fɔ tɔk.
• Wiknɛs wantɛm wantɛm : Na wan say na di bɔdi, yu an ɔ yu leg we yu de fil fɔ wik wantɛm wantɛm.
• Cognitive impairment : Memori de dכn, fכ disayd fכ disayd kin bi tranga.
• Epilepsy symptoms (Seizure) : I kin tan lɛk fit.

Sɔntɛnde, pɔrsin kin ivin go na kɔma bikɔs ɔf bɔrku blɔd.

Wetin rili de apin we `(CAA)` de?

Sεribra amyloid angiopathy na rili wan kayn εmoraji strok . If yu gɛt dis sik, wan abnɔmal prɔtin we dɛn kɔl amyloid dɔn gɛda ɛn stɔp na di insay pat pan di blɔd vesel dɛn na yu bren.

As di ia dɛn de go, di wɔl dɛn na yu blɔd vesel dɛn kin wik smɔl smɔl, ɛn dɛn kin mek maykroskɔpik krak ɔ fis dɛn we kin mek blɔd lik insay yu bren. We blɔd lik frɔm dɛn blɔd vesel ya, i kin pwɛl di bren tisu.

Bɔku tɛm, dis blɔd kin tan lɛk se taya de mek di briz kɔmɔt smɔl smɔl. Fɔs, yu nɔ kin fil bɔku difrɛns.

Bɔrku pipul nɔr kin tek tin lɛk wae pɔrsin nɔr de mɛmba ɛn kɔnfyus siriɔs wan fɔs. Dɛn kin tink se, "O, dis na jɔs sɔntin we kin apin we yu dɔn ol." Bɔt as tɛm de go, as di amyloid protin de pwɛl di blɔd vesel dɛn ɛn mek di blɔd we de lik insay di bren bɔku, di sayn dɛn kin wɔs smɔl smɔl.

Yu tink se dɛn kin mek `(CAA)` wantɛm wantɛm?

Bɔrku tɛm, i nɔr kin divɛlɔp so kwik. Bɔt i kin apin nɔmɔ if yu gɛt sɔm tin dɛn we de chenj na yu jɛnɛtiks we kin mek yu gɛt di sik. Fɔ ɛgzampul, di kayn sik we dɛn kin gɛt we dɛn kin gɛt frɔm dɛn mama ɛn papa we dɛn kɔl hereditary coronary artery disease (CAA) na wan bad bad strok we kin mek pɔsin in layf de pan denja.

Dɛn bad bad strok ya na di fɔs sayn dɛm. Ivin if dɛn nɔ day pan strok, leta dɛn kin gɛt dis maynia sik , epilepsy , ɛn strok bɔku tɛm we kin pwɛl di bren mɔ ɛn mɔ. Bɔrku pipul dɛm wae gɛt dis kayn CAA we dɛn kin gɛt frɔm dɛn mama ɛn papa kin day insay 10 ia afta dɛn dɔn gɛt dis sik. Bɔt yu fɔ mɛmba bak se CAA we pɔsin kin gɛt frɔm in mama ɛn papa nɔ kin bɔku .

Wetin na di rizin dɛn we mek dɛn mek `(CAA)`?

Masta sabi bukman dɛn nɔ no yet di rayt tin we kin mek i apin, bɔt risach dɔn sho se dɛn tin ya kin mek di sik bɔku:

• Alzaima: Pipul wae gɛt dis sik kin gɛt dis sik. dis kin bi biכs dεn tu sik dεm ya involv di protin amyloid.
• Neshɔn: .Risach dɔn sho se dis sik kin bɔku pan sɔm etnik grup dɛn. Fɔ ɛgzampul, sɔm stɔdi dɛn dɔn sho se CAA kin bɔku pan wayt pipul dɛn. Bɔt dis nɔto tin we de apin ɔlsay na di wɔl, ɛn dɛn nid fɔ du mɔ risach.
• Haypatɛnshɔn: Ay blɔd prɛshɔn na tin bak we de mek di risk fɔ gɛt CAA bɔku bay we i de put ɛkstra prɛshɔn pan dɛn blɔd vesel ya.

Aw ɛksaktɔli yu de rɛkɔgnayz `(CAA)`?

Dis na di pat we at pas ɔl. Nɔr way nɔr de fɔ rili kɔnfɔm dis sik wit 100% shɔ wae pɔrsin de alayv. Di wangren we fɔ kɔnfɔm am na fɔ tek di bren tisu afta i day ɛn chɛk am ɔnda maykroskɔp. Dat min se, wit wan ``ɔtopsi``.

Bɔt pan ɔl we i nɔ pɔsibul fɔ kɔnfɔm ``CAA'' bifo pɔsin day, dɔktɔ dɛn kin mek ``presumptive diagnosis'' se di sik go mɔs de. Dɛn kin du dis bay we dɛn de yuz:

• Magnetic Resonance Imaging (MRI) skan fɔ di bren: Dis kin no di smɔl smɔl blɔd we de klɔt (maykroblɔd) na di bren.
• wan `(PET)` skan (Positron Emission Tomography scan) wit (Amyloid tracer labeling) : dεn kin yuz dis fכ si if `(amyloid)` protin dεn dכn dכn na di bren.

Na di infɔmeshɔn we dɛn kin gɛt frɔm dɛn tɛst ya, na in dɔktɔ dɛn kin disayd if dɛn kin bi (CAA).

Tritmɛnt de fɔ `(CAA)`?

I sɔri fɔ no se, no patikyula mɛrɛsin nɔ de fɔ dis ɔ we nɔ de fɔ mek i nɔ apin.

So, if yu tɛst sho se yu kin gɛt dis sik, yu dɔktɔ go tray fɔ ridyus di chans fɔ mek yu gɛt blɔd na yu bren, fɔ mek yu gɛt mɔ blɔd, ɔ fɔ mek di blɔd we dɔn de, wɔs. Dat min se yu fɔ kɔntrol yu sik dɛn ɛn kɔntrol di sik fɔ mek i nɔ wɔs.

Fɔ gi sɔm ɛgzampul dɛn:

• Fɔ kɔntrol ay blɔd prɛshɔn: We yu gɛt ay blɔd prɛshɔn we nɔ de dɔn, dat kin mek yu bren blɔd kɔmɔt mɔ ɛn mɔ. If tɛst sho sayn dɛm fɔ ``CAA'' ɛn yu gɛt ay blɔd prɛshɔn bak, yu dɔktɔ go wach yu ɔl wɛl bɔdi ɛn blɔd prɛshɔn gud gud wan. Dɛn kin tɛl yu bak se yu fɔ tek mɛrɛsin ɛn chenj yu layf (di it, ɛksesaiz) fɔ mek yu blɔd prɛshɔn go dɔŋ.
• Tek tɛm wit tin dɛn we de mek yu blɔd tan: If yu gɛt CAA ɛn yu de tek tin dɛn we de mek yu blɔd blɔd, lɛk wɔfarin ɔ aspirin, fɔ wan sik we de mek yu blɔd klɔt, i kin mek yu bren blɔd bad bad wan. If yu gɛt dis sik, yu dɔktɔ kin tɛl yu fɔ stɔp fɔ tek di blɔd tin fɔ it ɛn i kin tɛl yu ɔda we dɛn we nɔ go mek yu blɔd nɔ klɔt. Na dat mek i impɔtant fɔ tɛl yu dɔktɔ bɔt ɔl di mɛrɛsin dɛn we yu de tek.

Aw lɔŋ yu kin liv wit `(CAA)`?

Dis na kwɛstyɔn we bɔku pipul dɛn kin aks. Bɔt, i nɔ kin izi fɔ gi wan ansa. I kin difrɛn bad bad wan dipen pan di tin we de apin to yu.

Yu ej, di kayn sik wae yu gɛt naw, yu ɔl wɛl bɔdi, ɛn ɔda mɛrɛsin wae de mek yu gɛt siriɔs blɔd na yu bren (e.g., dayabitis, ay kɔlɔstrel) ɔl de afɛkt aw lɔng yu go liv.

Yu dɔktɔ na di bɛst pɔsin fɔ no bɔt wetin fɔ ɛkspɛkt. I go no di patikyula tin we de apin to yu ɛn i go ebul fɔ advays yu fɔ du dat.

Aw a go tek kia ɔf misɛf?

We yu kam fɔ no se yu gɛt (CAA), i impɔtant fɔ tek kia ɔf yusɛf. Fɔ ɔndastand yu risk na de bɛst tin wae yu kin du fɔ kia fɔ yusɛf.

Fɔ ɛgzampul, if tɛst sho se yu gɛt ``(CAA)'' bɔt yu nɔ gɛt big big sik, yu dɔktɔ kin advays yu bɔt aw fɔ mek yu nɔ gɛt ay blɔd prɛshɔn ɔ fɔ avɔyd tin dɛn we nɔ nid fɔ mek yu blɔd tan. Dis inklud:

• Chek yu blɔd prɛshɔn ɔltɛm ɛn kɔntrol am lɛk aw yu dɔktɔ se.
• It tin dɛn we go mek yu gɛt wɛlbɔdi.
• Ɛksesaiz ɔltɛm.
• If yu de smok, stɔp.

Ustɛm a fɔ go to dɔktɔ?

If yu sik de wɔs, go to yu dɔktɔ wantɛm wantɛm.

Fɔ ɛgzampul, CAA kin afɛkt di we aw yu de mɛmba ɛn aw yu de tink. If yu ɔ pɔsin we yu sabi gɛt prɔblɛm wit mɛmori (fɔgɛt wɔd, lɔs), ɔ if yu de kɔnfyus ɔ yu gɛt prɔblɛm fɔ tɔk pas aw yu bin de tɔk pas aw i bin de bifo, yu dɔktɔ go want fɔ tɛst yu fɔ si if yu gɛt nyu blɔd na yu bren. So nɔ ignore dɛn chenj ya.

Ustɛm a fɔ go na di imejensi rum?

Dis rili impɔtant. If di sayn dɛn we de sho se yu sik bad bad wan wantɛm wantɛm, lɛk ed we de at, kɔnfyushɔn, i nɔ izi fɔ tɔk, ɔ yu nɔ de no natin, yu fɔ go na ɔspitul wantɛm wantɛm.

Bikɔs yu go dɔn gɛt ɛmoraji strok, we na strok we pɔsin kin gɛt we i de blɔd we kin mek yu bren pwɛl ɔ day fɔ ɔltɛm. Fɔ gɛt tritmɛnt kwik afta yu gɛt strok na impɔtant tin fɔ sev pipul dɛn layf ɛn fɔ ridyus di disabled fɔ lɔng tɛm.

Na sɔm sayn dɛn we de sho se pɔsin gɛt strok:

• Wan say na di fes we de sag: Yu nɔ kin ebul fɔ es wan say na di fes fayn fayn wan we yu de smayl.
• Wiknɛs na wan an: We dɛn aks am fɔ es in tu an fɔ go bifo, wan an kin drɔp dɔŋ.
• I nɔ izi fɔ tɔk: wɔd dɛn kin tan lɛk, yu nɔ kin ɔndastand wetin dɛn de tɔk.
• Sɔdɛn bad bad ed pen: Na bad bad ed pen lɛk aw i nɔ ɛva bi na yu layf.

If yu si ɛni wan pan dɛn sik ya, nɔ west tɛm ɛn go na ɔspitul wantɛm wantɛm.

Us kwɛstyɔn dɛn a fɔ aks di dɔktɔ?

If yu tɛst sho se yu kin gɛt (CAA), i nɔmal fɔ gɛt bɔku kwɛstyɔn. Na sɔm kwɛstyɔn dɛn we yu kin aks yu dɔktɔ:

• Wetin rili mi MRI ɔ PET skan dɛn de sho?
• A gɛt blɔd we de kɔmɔt insay mi bren? Aw i rili bad?
• I pɔsibul se dis blɔd go wɔs?
• Wetin na di risk we a kin gɛt fɔ gɛt strok?
• Aw dis go afɛkt di we aw a de mɛmba ɛn di we aw a de tink?
• Us chenj dɛn we a nid fɔ chenj mi layf?
• Us mɛrɛsin dɛn a kin tek? Dɛn gɛt bad bad tin dɛn we kin apin to dɛn?
• Aw kwik a fɔ gɛt tɛst bak?

Na `(CAA)` sɛf `(Dimɛnshɔn)`?

Nɔ, dɛn nɔto di sem. Bɔt sɔntin de we gɛt fɔ du wit dɛn tu tin ya. Sεribral Amyloid Angiopathy kin mek yu gɛt ɛmoraji strok . Dɛn strok ya kin pwɛl di bren sɛl dɛm, we kin mek pɔsin gɛt vaskul dimɛnshɔn . Dimɛnshɔn na wan sik wae de mek yu bren nɔr de woke fayn lɛk fɔ mɛmba, fɔ tink, fɔ tɔk, ɛn fɔ jɔj. So, CAA kin bi wan tin wae kin mek yu gɛt vaskul dimɛnshɔn.

Fɔ dɔn, tin dɛn fɔ mɛmba (Take-Home Message) .

sεribral Amyloid Angiopathy (CAA) na wan sik we kin bi siriכs kכndyushכn we di protin amyloid de dכn na di bכdi vεsul dεm na di bren, we kin mek di bכdi bכn.

• Di fɔs sayn dɛm kin rili shɔt – lɛk smɔl mɛmori, fɔgɛt wɔd. Bɔt dɛn tin ya kin tranga mɔ ɛn mɔ as tɛm de go.
• Nɔr patikyula mɛrɛsin nɔr de fɔ dis, bɔt dɛn kin ebul fɔ kɔntrol di sayn dɛm ɛn kɔntrol di sik. Fɔ kɔntrol blɔd prɛshɔn ɛn fɔ fala wɛlbɔdi layf rili impɔtant.
• If yu gɛt ɛni sayn we yu go sɔprayz (espɛshali yu mɛmori, kɔnfyushɔn, nyurolɔjik chenj wantɛm wantɛm), go to dɔktɔ wantɛm wantɛm.
• If yu no bɔt di (CAA) go ɛp yu ɛn di wan dɛn we yu lɛk fɔ bia wit dis tin.

A op se dis infɔmeshɔn go ɛp yu. If yu gɛt ɛni kwɛstyɔn, nɔ shem fɔ tɔk to yu dɔktɔ.

` sεribra amyloid angiopathy, CAA, bren blɔd, maykroblid, intrakranial εmoraji, kכgnitiv dεklin, εmoraji strכk, amyloid protin, dimεnshכn, Alzaima, haypatεnshכn, MRI, PET skan, bren blɔd, amyloid, mεmכri lכs, strok