Yu tink se di tritmɛnt fɔ kansa kin afɛkt yu at? Mek wi tok boht cardiotoxicity!

Yu de du tritmɛnt fɔ kansa? Ɔ pɔsin we yu sabi de du dis kayn tritmɛnt? Sɔntɛnde, di tritmɛnt fɔ kansa kin gɛt smɔl impak pan wi at. Na dat wi go tok abaut tide. Wi kin kɔl dis kadiotoksisiti . Nɔ wɔri, lɛ wi ɔndastand dis simpul wan.

So wetin na kadiɔtoksisiti?

Fɔ tɔk am simpul wan, cardiotoxicity na di damej we wi at kin gɛt bikɔs ɔf sɔm kansa tritmɛnt ɔ kansa mɛrɛsin. Yu fɔ mɛmba se, sɔmtɛm dis ifɛkt kin apin ivin sɔm ia afta dɛn dɔn trit yu kansa. Dis risk kin bɔku mɔ fɔ big pipul dɛn we dɛn bin dɔn trit fɔ kansa we dɛn bin yɔŋ, dat na we dɛn bin smɔl. Nɔto ɔl di tritmɛnt dɛm fɔ kansa kin mek dis, bɔt sɔm tritmɛnt dɛm de wae gɛt bɔrku risk fɔ mek pɔrsin gɛt dis sik.

Dis sik kin mek i nɔr izi fɔ yu at fɔ pɔmp blɔd fayn fayn wan ɔlsay na yu bɔdi. Sɔntɛnde, dis kin ivin mek yu gɛt wan sik na yu at mɔsul dɛn we dɛn kɔl cardiomyopathy , we kin mek i nɔ izi fɔ yu at fɔ pɔmp blɔd.

Udat dɛn kin gɛt mɔ prɔblɛm wit di sik we dɛn kɔl cardiotoxicity?

Infakt, ɛnibɔdi we dɔn gɛt kansa tritmɛnt kin gɛt prɔblɛm wit in at. Bɔt di risk kin bɔku fɔ di wan dɛn we dɔn yuz sɔm mɛrɛsin dɛn ɔ we dɔn gɛt redyushɔn tɛrapi to di eria na dɛn chɛst.

Dɔn bak, lɛk aw wi bin dɔn tɔk, dis sik kin apin smɔl pan pipul dɛn we dɛn dɔn trit fɔ kansa we dɛn smɔl, dat na we dɛn big. I nɔ kin izi fɔ tɔk klia wan aw dis kin apin to pipul dɛn we dɔn gɛt kansa we dɛn dɔn big. Bɔt sɔm ripɔt dɛn sho se lɛk 20% pan dɛn pipul ya kin gɛt at sik, ɛn bitwin 7% ɛn 10% kin gɛt kadiomayopathy ɔ at pwɛl. So i rili impɔtant fɔ no bɔt dis.

Aw dis cardiotoxicity de afɛkt yu bɔdi?

Cardiotoxicity kin mek yu gɛt difrɛn prɔblɛm dɛn na yu at. Lɛ wi tek wan luk pan wetin dɛn bi:

• Cardiomyopathy: Dis na we di at mɔsul kin wik ɛn di at nɔ kin ebul fɔ pɔmp blɔd fayn fayn wan.
• Mayokardial Infarkshɔn ɔ At Atak: Sɔntɛm yu dɔn yɛri bɔt dis wan. I kin bi bikɔs di at dɛn we de gi blɔd to di at kin blok.
• Koronari At Diziz: Di at we de kɛr blɔd go na di at de smɔl ɔ blok.
• Hat Failure: Di at nɔ kin ebul fɔ pɔmp blɔd fɔ mit di bɔdi in nid.
• At Valv Sik: At valv nɔ de wok fayn.
• At we nɔ de bit ɔltɛm (Aritmia):At nɔ de bit ɔltɛm, i kin bit am sloslo, kwik kwik wan, ɔ i nɔ kin bit am.
• Fluid Buildup Arawnd di At.
• Lɔw ɔ Ay Blɔd Prɛshɔn.
• Di at we de rit sloslo.
• Constrictive Pericarditis: pan dis kכndyushכn, di כta mεmbran na di at de tik, we de rεdכks di spεs fכ di at fכ εkspכnd fri wan.

Wetin na di sayn dɛm wae de sho se yu gɛt cardiotoxicity?

Bɔrku sayn dɛm de fɔ hat sik wae gɛt fɔ du wit kardiotoxicity. If yu gɛt wan ɔ mɔ pan dɛn tin ya, i impɔtant fɔ mek yu wɔri:

• Abdominal distension: di bεlε de bulge fכ go bifo, lεk bכl.
• Chɛst Pen: Di chɛst kin fil tayt ɔ kɔnstrikt.
• Diziz we pɔsin kin gɛt.
• At Palpitations: Imajin se yu de fil lɛk se yu at de rɔn insay yu chɛst, ɔr de bit lawd wan.
• Dispnea ɔ Shortness of Breath: Yu kin fil shɔt fɔ blo ɛn yu kin blo ivin afta yu dɔn du smɔl tin.
• di leg dεm de swεla εn di wata we de rεtεn (edema): I de swεla, spεshal wan na di leg dεm εn di ankכl dεm.

Wetin na di men tin dɛm wae kin mek pɔrsin gɛt cardiotoxicity?

Sɔm tritmɛnt dɛn de we kin mek pɔsin gɛt kansa we kin mek pɔsin gɛt at sik. Di tin dɛn we impɔtant pas ɔl na:

• Antrasayklin: Fɔ ɛgzampul , Dɔksorubisin (Adriamycin®) . Dis na wan kayn kemotɛrapi mɛrɛsin we dɛn kin yuz fɔ mɛn kansa lɛk lukimiya, limfoma, bɔdi kansa, sarkoma, ɔ maltipul mayloma .
• Trastuzumab (Herceptin®): Dis na wan targeted therapy drug we dɛn kin yuz fɔ trit brɔst kansa, bɛlɛ kansa, ɔ kansa na di gastroesophageal junction. Risk de fɔ mek yu gɛt kadiomayopathy, mɔ we dɛn gi dis mɛrɛsin wit wan antrasayklin.
• Radiation Therapy to the Chest: Dɛn kin yuz dis bak fɔ mɛn sik dɛn lɛk bɔdi kansa ɔ lukimiya .

Aw dɔktɔ dɛn kin no dis sik we de mek pɔsin gɛt at sik?

Dɔktɔ dɛn kin luk mɔ pan aw yu at de pɔmp blɔd fayn fayn wan fɔ no if yu gɛt cardiotoxicity. Dɛn kin mɛzhɔ dis bay wan tɛst we dɛn kɔl di Left Ventricular Ejection Fraction (LVEF) . Dɛn kin luk bak aw yu at valv dɛn de wok fayn fayn wan. di LVEF de mכsu aw mכch bכdi de pכmp kכmכt na di lכw chεmba na di lεft say na yu at (di Lεft Vεntrikl) wan tεm.

Bɔku tɛst dɛn de we dɔktɔ dɛn kin yuz fɔ no dɛn tin ya:

• Echocardiogram: Dis na di men imej tɛst we dɛn kin yuz bɔku tɛm fɔ no if pɔsin gɛt di at. I de yuz ilɛktrɔd ɛn ɔltra saund wev fɔ chɛk yu at rit ɛn di we aw blɔd de flɔ tru yu at. I tan lɛk di skan we dɛn kin du fɔ mama dɛn we gɛt bɛlɛ, bɔt dis wan na fɔ di at.
• Cardiac MRI: Sɔm spɛshal pipul dɛn se dis na di gold standad tɛst fɔ no if pɔsin gɛt di at. I de yuz magnet, redio wev, ɛn spɛshal kɔmpyuta fɔ tek ditayli pikchɔ dɛn bɔt di tin dɛn we de na yu at ɛn fɔ no aw blɔd de flɔ tru am.
• Kadyak Strɛs Tɛst: Dis tɛst de mɛzhɔ aw yu at de ansa we yu de du tin tranga wan. Dɛn kin aks yu fɔ waka pan tredmil ɔ rayd bayk we nɔ de muv. Insay dis tɛm, dɛn kin kɔnɛkt yu to wan mashin we de mɛzhɔ yu at rit ɛn blɔd prɛshɔn.
• Multigated Acquisition Scan (MUGA): dis tεst de evaluate di wok we yu at chεmba dεm (vεntrikul dεm) de du. Dɛn kin yuz wan sef redioaktiv traysa fɔ dis. Yu kin si am klia wan pan di skan. Di dɔktɔ kin wach aw dis traysa de muv tru yu blɔd vesel dɛn, dɔn i kin kɔl yu ejection fraction.
• Cardiac CT Scan: CT scan de tek X-ray frɔm difrɛn angul dɛn fɔ mek yu gɛt ditayli pikchɔ bɔt di at. Dis tɛst kin rili yusful, mɔ fɔ pipul dɛn we de sɔspɛkt se dɛn gɛt kadiɔtoksisiti afta dɛn dɔn gi dɛn raytin tɛrapi to dɛn chɛst.

Aw dɛn kin trit dis kadyotoksisiti kɔndishɔn?

Dipen pan di mɛrɛsin dɛn we yu de tek naw, yu dɔktɔ kin tɛl yu fɔ stɔp sɔm pan dɛn ɔ fɔ ridyus di doz we dɛn de tek. Yu dɔktɔ kin gi yu mɛrɛsin bak we go ɛp yu at fɔ wok fayn fayn wan. Fɔ ɛgzampul:

• ACE inhibitors: Fɔ ɛgzampul , Lisinopril (Zestril®) ɔ Fosinopril Sɔdiɔm (Monopril®) .Ok. Wetin dɛn tin ya kin du na fɔ opin yu at ɛn mek i izi fɔ mek blɔd kɔmɔt.
• Beta-blɔka: Fɔ ɛgzampul , mɛtoprolɔl (Lopressor®) ɔ atenɔlɔl (Tenormin®) . Dɛn tin ya kin mek di blɔd flɔ ɛn mek di at rit slo.
• Digoxin, we dɛn kin kɔl bak Digitalis (Lanoxin®): Dis kin mek di at rit slo ɛn i kin ɛp di at fɔ bit fayn fayn wan.
• Diuretics (dɛn kin kɔl am bak wata pils): Fɔ ɛgzampul , Furosemide (Lasix®) . dis dεm de wok bay we dεn de pul di wata (wata) we pasmak na di bכdi tru di urine.
• Vasodilators: Fɔ ɛgzampul , Isosorbide Dinitrate (Isordil®) . Dɛn tin ya de wok bay we dɛn de mek di blɔd vesel dɛn big (opin), we de mek di blɔd flɔ izi wan.

Ɛnitin de we wi kin du fɔ ridyus di risk fɔ gɛt cardiotoxicity?

Infakt, no we nɔ de fɔ mek dɛn nɔ gɛt di sik we dɛn kɔl cardiotoxicity kpatakpata. Bɔt if dɛn no se yu gɛt kansa, i rili impɔtant fɔ tɔk to yu dɔktɔ bɔt di gud ɛn bad tin dɛn we yu kin du fɔ mɛn yu, dat na di prɔblɛm dɛn we kin apin to yu wɛlbɔdi ɛn di bɛnifit dɛn we yu kin gɛt.

Dɔn bak, fɔ du at imej tɛst ɔltɛm we dɛn de trit kansa kin ɛp fɔ no if pɔsin gɛt di sik we de mek pɔsin in at pwɛl kwik kwik wan. Jɔs tink bɔt, if prɔblɛm de, di mɔ we dɛn no am kwik kwik wan, na di mɔ dɛn go ebul fɔ trit am fayn.

Yu tink se dis kadyotoksisiti kɔndishɔn kin rivɛns, dat na fɔ mɛn am?

Sɔntɛnde, yɛs. Kes dεm de we dεn kin rivεs di kכdiotoksisiti. Risach dɔn sho se di cardiotoxicity afta yu dɔn yuz wan drɔg we dɛn kɔl Trastuzumab kin rivɛns.

Bɔt bɔku tɛm, i nɔ kin izi fɔ rivɛns di kadyotɔksisiti we kin kam bikɔs dɛn yuz antrasayklin. I nid fɔ gɛt tritmɛnt fɔ lɔng tɛm. Semweso, di kadiotoksisiti we gɛt fɔ du wit di chɛst raytin sɛf rili at fɔ rivɛns. Sɔntɛnde , dɛn kin nid fɔ gɛt tritmɛnt fɔ lɔng tɛm, ɛn ivin ɔpreshɔn.

Ustɛm a fɔ go to dɔktɔ wantɛm wantɛm? Wetin fɔ du we ɛnitin apin we nɔ izi fɔ du?

If yu gɛt ɛni sayn fɔ siriɔs at sik, kɔl 911 wantɛm wantɛm fɔ ambulans, ɔ go na di imejensi rum we de nia yu. Yu fɔ no mɔ bɔt dɛn sayn ya:

• Palpitations ɔr de fil se yu at de bit kwik kwik wan we de kɔntinyu.
• Diziz, fil lɛk yu ed layt, ɔ yu de pas.
• Wantɛm we yu nɔ de blo fayn ɔ yu de fil pen na yu chɛst.
• Di trot ɔ di lip dɛn we de swel.
• Di swel we nɔ kɔmɔn na di leg ɔ fut.
• di wet we yu de gεt pas 1.5 kg (3 paund) insay wan wik.

If yu gɛt dɛn sik ya , i impɔtant fɔ go to dɔktɔ wantɛm wantɛm ɛn yu nɔ go west yu tɛm, bikɔs dɛn tin ya kin bi sayn fɔ se yu gɛt siriɔs sik, lɛk at atak.

Fɔ dɔn, di mɛsej we impɔtant pas ɔl we yu go kɛr go na os!

Okay, wi don tok plenti boht cardiotoxicity. Fɔ tɔk am simpul wan, cardiotoxicity na damej pan di at we kin kam bikɔs ɔf tritmɛnt fɔ kansa. E kin pasmak pan pipul dɛm wae dɔn gɛt sɔm kayn kemotɛrapi drɔgs, targeted therapy drugs, ɔr redyushɔn tɛrapi to dɛn chɛst.

Wae sɔm kayn cardiotoxicity kin rivεs, ɔda wan dεm kin nid fɔ trit fɔ lɔng tɛm. Di tin we impɔtant pas ɔl na fɔ tɔk opin wan wit yu dɔktɔ bɔt di bɛnifit ɛn di prɔblɛm dɛn we yu go gɛt we yu de trit yu if yu de gɛt kansa tritmɛnt. Dɔn bak, if yu de du yu at tɛst ɔltɛm we yu de trit yu, dat kin ɛp fɔ no ɛni prɔblɛm kwik kwik wan ɛn bigin fɔ trit yu kwik kwik wan.

Nɔ panik, bɔt na fɔ no. Tek kia ɔf yu at. If yu gɛt ɛni ɔda sayn we nɔ kɔmɔn, nɔ ignore am. Go to dɔktɔ wantɛm wantɛm.

` Kadyotoksisiti, Kansa Tritmɛnt, At Sik, Kimotɛrapi, Rɛdieshɔn Tɛrapi, At Wɛlbɔdi, Kadiotoksisiti