Yu dɔn ɛva gɛt wan ɔnusual lump ɔ growth ɔnda di skin na yu leg ɔ an we jɔs nɔ go go? I nɔ go ivin at we yu prɛs pan am. Bɔt if i fil lɛk se i de big, i kin bi sɔntin we yu fɔ wɔri bɔt. Tide wi go tɔk bɔt wan kansa we nɔ kin bɔku we kin mek pɔsin gɛt di sem kayn sik, bɔt i fayn fɔ mek wi no bɔt am. Dɛn kɔl am Klia Sɛl Sarkoma .
Wetin na Klia Sɛl Sarkoma?
Fɔ tɔk am simpul wan, klia sɛl sarkoma na wan kayn kansa we kin apin na di sɔft tisu dɛn . I de insay wan kategori we dɛn kɔl sarkoma . Bɔku tɛm, dɛn kansa ya kin bigin na di tɛndon , di tisu dɛn we de kɔnɛkt di mɔsul dɛn to di bon dɛn, ɛn di sɔft tisu dɛn we de rawnd di mɔsul dɛn, na yu leg dɛn, mɔ yu fut dɛn.
Lɛk ɔda kayn kansa, klia sɛl sarkoma kin izi fɔ trit if dɛn fɛn am bifo i spre to ɔda pat dɛn na di bɔdi. Dɔktɔ dɛn kin trit dis sik mɔ wit ɔpreshɔn , ɛn if nid de , redyushɔn tɛrapi ɛn sɔntɛnde kemotɛrapi . Bɔt i sɔri fɔ no se ivin afta dɛn dɔn trit am, di sik kin gɛt bɔku chans fɔ kam bak. Na dat mek pipul dɛn we de stɔdi bɔt mɛrɛsin de luk ɔltɛm fɔ nyu we fɔ mɛn klia sɛl sarkoma.
Aw klia sɛl sarkoma kin afɛkt mi bɔdi?
Bɔku tɛm, klia sɛl sarkoma kin bigin na di dip sɔft tisu we de rawnd yu tɛndon ɛn mɔsul dɛn, ɔ insay wan layt we dɛn kɔl fascia . Fascia tan lɛk band we de rap rawnd ɛvri strɔkchɔ na wi bɔdi.
Fɔs, yu nɔ go notis ɛnitin. Bɔt yu go notis am we di kansa de gro ɛn bi wan smɔl smɔl tin we yu kin fil ɔnda di skin na yu leg ɔ yu fut. Dis lump kin tan lɛk lump we kin apin we yu nak yu leg ɔ yu fut tranga wan, bɔt di impɔtant difrɛns na dat dis lump nɔ kin shrink as tɛm de go . Klir sel sarkoma de gro sloslo. Bɔt bay di tɛm we i dɔn skata frɔm yu dip sɔft tisu dɛn we de ɔnda di skin, i go dɔn ɔlrɛdi bigin fɔ skata to ɔda pat dɛn na yu bɔdi.
Imajin, yu gɛt smɔl bɔmp na yu leg ɛn yu ignore am, tink se, "O, dis go mɔs dɔn jɔs apin." Afta wiks ɔ mɔnt, i stil de, sɔntɛm i ivin big smɔl. If na so i bi, i go mɔs bi se i go fayn fɔ mek yu go to dɔktɔ.
Usay klia sɛl sarkoma de skata?
Klia sel sarkoma kin spre to ɔda pat dɛn na di bɔdi, mɔ:
- Yu dijestiv sistɛm (gastrointestinal tract) .
- Na yu yonTo di lɔng dɛn
- yu limf sistεm , we na di limf no dεm εn di limf vεsεl dεm na yu bכdi.
Dis na tin we pipul dɛn kin gɛt?
Nɔ, nɔto so atɔl. Dis na wan sɔbtayp fɔ kansa we nɔ kin bɔku. Infakt, sarkoma na wan kayn kansa bak we nɔ kin bɔku. Fɔ ɛgzampul, na Amɛrika, ɛvri ia, na lɛk 1,600 pipul dɛn kin gɛt dis sik we dɛn kɔl sarkoma. Dat na smɔl nɔmba, lɛk 1% pan ɔl di kansa dɛm na big pipul dɛm. Klia sel sarkoma, dat na jכs 1% pan כl di sarkoma. So yu kin imajin aw dis nɔ kin apin so ɔltɛm.
Udat kin gɛt klia sɛl sarkoma?
Pan ɔl we klia sɛl sarkoma kin kam pan ɛni ej, dɛn kin si am mɔ pan yɔŋ pipul dɛn we ol bitwin 15 ɛn 40 ia , mɔ di wan dɛn we ol 20 ɛn 30 ia.
Wetin na di sayn dɛm fɔ klia sɛl sarkoma?
As wi bin dɔn tɔk bɔt bifo tɛm, di tin we kin apin mɔ na yu bɔdi we nɔ de go ɔnda di skin na yu leg ɔ yu fut . Dis lump kin at ɔ i nɔ kin at. Bɔt if i de de ɛn fil lɛk se i de big, dat na big sayn.
Apat frɔm dat, dɛn sayn ya kin apin leta:
- Taya pasmak fɔ natin
- We yu de lɔs yu wet we yu nɔ ɛksplen
- Nayt swet dɛn
Wetin kin mek pɔsin gɛt klia sɛl sarkoma?
Dis na tin we kɔmplikt smɔl. Di wan dɛn we de stɔdi bɔt mɛrɛsin dɔn kam fɔ no se klia sɛl sarkoma kin kam bikɔs sɔm pat dɛn pan tu kromozom dɛn na wi bɔdi sɛl dɛn kin chenj ples, ɛn dis kin mek wan nyu jin we dɛn dɔn jɔyn .
Fɔ tɔk am simpul wan, na dis kin apin:
We wi bɔdi in sɛl dɛn sheb, sɔntɛnde tu kromozom dɛn kin brok ɛn di pat dɛn we brok kin chenj wit dɛnsɛf. insay dis kes, di kromozom sεgmεnt dεm we dεn swap gεt jin dεm we dεn kכl EWSR1 εn ATF1 . i lεk se di protin we di EWSR1 jin de prodyuz imכtant fכ di sεl fכ wok. di ATF1 jin de εp fכ kכntrכl di sεl dεm we de gro. we dεn kromozom dεm ya kam bak togeda, di jin sεgmεnt dεm we dεn swap de εnd כp na di rכng ples dεm. Dɔktɔ dɛn kɔl dis wan rɛsiprokal translokeshɔn . Wi nɔ no di rayt rizin we mek dis kin apin stil.
we dεn tכn to nyu kromozom, di jin dεm we dεn sכp de kam tכgeda fכ mek wan fכs jin we dεn kכl EWSR1/ATF1 . Risach pipul dεm biliv se dis fuz jin na di men tin we de mek klia sεl sarkoma.
Aw dɔktɔ dɛn kin no se pɔsin gɛt klia sɛl sarkoma?
We yu go to dɔktɔ we gɛt wan bɔm lɛk dat, i go fɔs chɛk yu ɛn chɛk usay di bɔm de, in saiz, ɛn ɔda tin dɛn. Dɔn yu kin nid fɔ du MRI skan (Magnetic Resonance Imaging - MRI).I pɔsibul.
Bɔt dɛn kin no se pɔsin gɛt klia sɛl sarkoma bay we dɛn tek bayɔpsi, we kin min fɔ tek wan smɔl pat pan di tisu frɔm di lump . we dεn egzamin dis tisu sεmpl כnda maykroskכp, di patכlayz dεm, di spεshal pipul dεm we de egzamin di tisu na di lab, de luk fכ di prεsεns fכ di EWSR1/ATF1 fכs jin we wi bin tכk bכt bifo.
Aw dɛn kin trit klia sɛl sarkoma?
Di men gol fɔ dɔktɔ dɛn na fɔ stɔp klia sɛl sarkoma fɔ mek i nɔ go ɔlsay na di bɔdi. Bɔku tɛm, di fɔs tin we dɛn kin du na fɔ du ɔpreshɔn fɔ pul di tumbu kɔmɔt kpatakpata . If di kansa dɔn skata to di limf no dɛm, dɛn kin pul dɛn limf no dɛm de bak. Dis kin fala wit adjuvant tɛrapi . Bɔku tɛm dis kin gɛt fɔ du wit redyushɔn tɛrapi fɔ kil ɛni kansa sɛl we lɛf.
Naw, pipul dɛn we de stɔdi bɔt mɛrɛsin de fɛn ɔda tritmɛnt dɛn. Fɔ ɛgzampul, dɛn de luk aw imyunotɛrapi de wok fayn fɔ kɔntrol klia sɛl sarkoma. Dɛn de tɛst bak if di mɛrɛsin dɛn we dɛn de yuz naw fɔ mɛn ɔda kayn kansa kin ɛp fɔ stɔp di prɛd we klia sɛl sarkoma de prɛd.
Di impɔtant tin na dat klia sɛl sarkoma na wan sik we kin kam bak bɔku tɛm. If dat apin, yu go nid fɔ du mɔ ɔpreshɔn ɛn mɔ redyushɔn tɛrapi. Ɛn bikɔs i kin skata kwik kwik wan, dɔktɔ dɛn go de chɛk yu ɔltɛm fɔ si if nyu tumbu dɛn de kam.
A kin ridyus di risk fɔ gɛt klia sɛl sarkoma?
Bɔt i sɔri fɔ no se natin nɔr de wae yu kin du fɔ ridyus yu risk fɔ gɛt dis sik. Bikɔs di wan dɛn we de stɔdi bɔt mɛrɛsin nɔ dɔn no yet ɛni patikyula tin we kin mek pɔsin gɛt klia sɛl sarkoma. Risk factor na wan aktiviti ɔr kɔndishɔn wae de mek yu gɛt mɔr chans fɔ gɛt sik.
Yu tink se dɛn kin mɛn klia sɛl sarkoma kpatakpata?
Dɔktɔ dɛn kin trit klia sɛl sarkoma, we min se dɛn kin pul di tumbu ɛn tray fɔ kɔntrol di we aw i de skata. Bɔt, i nɔto sik we pɔsin kin mɛn ɔltogɛda . Bɔku tɛm, klia sɛl sarkoma kin spre to ɔda pat dɛn na di bɔdi bay di tɛm we dɛn no se i gɛt am. Dis kin mek i nɔ izi fɔ trit am. I kin kam bak bak afta dɛn dɔn trit am.
Wetin na di layf we pɔsin we gɛt klia sɛl sarkoma de liv?
Di layf we yu go liv na di rough estimate of aw lɔng yu go liv, bay yu ɔl yu wɛl bɔdi ɛn yu pasɔnal tin dɛm. Wan rivyu we dɛn bin du insay 2018 pan di US National Cancer Database sho se pan pipul dɛn we gɛt klia sɛl sarkoma, .I bin tɔk bak se 50% stil de alayv fayv ia afta dɛn dɔn no se dɛn gɛt di sik, ɛn 38% stil de alayv tɛn ia afta dɛn dɔn no se dɛn gɛt di sik .
Ilɛksɛf wi de tɔk bɔt aw pɔsin kin liv ɔ aw pɔsin kin liv, i impɔtant fɔ mɛmba se dɛn tin ya na jɔs ɛstimat, nɔto prɛdikshɔn. Di layf we pɔsin kin liv na ɛstimat bay di wan ol pipul dɛn. Di rεt wae dεn de liv wit kansa na εstimat bay aw lכng pipul dεm de liv afta dεn trit dεm fכ wan patikyula kayn kεnsar. Bɔrku tin de wae kin afɛkt pɔrsin in layf ɔr chans fɔ gɛt kansa. If yu gɛt klia sɛl sarkoma, yu dɔktɔ kin gi yu di bɛst infɔmeshɔn bɔt wetin fɔ ɛkspɛkt.
Yu tink se klia sɛl sarkoma kin kil pɔsin?
Yɛs, i kin kil pɔsin. Jɛnɛral wan, pipul dɛm wae dɛn klia sɛl sarkoma dɔn spre to ɔda pat dɛm na dɛn bɔdi kin day kwik pas di wan dɛm wae gɛt tritmɛnt bifo di kansa skata.
Ustɛm a fɔ go to mi dɔktɔ?
Bikɔs klia sɛl sarkoma kin kam bak afta yu dɔn trit yu, yu dɔktɔ kin want fɔ si yu ɛvri tri mɔnt fɔ di fɔs tu ia afta yu dɔn dɔn di tritmɛnt, i go dipen pan yu kɔndishɔn. I impɔtant fɔ de chɛk-ap ɔltɛm afta dat.
Us kwɛstyɔn dɛn a fɔ aks mi dɔktɔ?
Klia sɛl sarkoma na sik we nɔ kin apin so ɔltɛm. I kin mek pɔsin in layf de pan denja. If dɛn no se yu gɛt dis sik, yu kin aks yu dɔktɔ dɛn kwɛstyɔn ya:
- Usay di tumbu de? Aw big i bi?
- Di tumbu dɔn skata ɛni ɔda say na mi bɔdi?
- Us tritmɛnt dɛn yu kin advays?
- Wetin na di sayd ɛfɛkt dɛm we di tritmɛnt kin gɛt?
- If dɛn du mi ɔpreshɔn, wetin na di chans fɔ mek di tumbu kam bak?
- Ɛni klinik trial dɛn de we a kin tink bɔt?
Sɔma ɛn Mɛsej we dɛn kin kɛr go na os
Clear Cell Sarcoma na wan sik we rili tranga. I nɔ kin apin so ɔltɛm. Na wan wan pipul dɛn nɔmɔ i kin afɛkt insay wan ia. Ɛn i kin gro smɔl smɔl. Di sarkoma kin skata ɛn kil am bay di tɛm we bɔku pipul dɛn notis chenj na dɛn bɔdi.
Bɔt mɛmba se dɔktɔ dɛn kin trit klia sɛl sarkoma. Dɛn kin pul di tumbu wit ɔpreshɔn, ɛn dɛn kin gi yu tritmɛnt bak fɔ kil ɛni kansa sɛl we lɛf. Bɔt i sɔri fɔ no se bɔku tɛm, klia sɛl sarkoma kin kam bak. So i impɔtant fɔ de chɛk-ap ɔltɛm ɛn no if ɛnitin chenj na yu bɔdi.
Di wan dɛn we de stɔdi bɔt mɛrɛsin de luk fɔ nyu we fɔ trit klia sɛl sarkoma. If yu gɛt klia sɛl sarkoma, nyu klinik trial dɛn de.If yu want fɔ no mɔ bɔt am, aks yu dɔktɔ bɔt am ɛn gɛt advays. Nɔ ɛva giv ɔp op. If yu gi yu di rayt advays ɛn sɔpɔt yu fɔ mɛn yu, yu go ebul fɔ bia wit dis prɔblɛm.
👩🏽 ⚕️ Ɔda kwɛstyɔn dɛn (FAQ dɛn)
💬 Na Klia Sɛl Sarkoma (CCS) na kansa na di skin (Melanoma)?
Nɔ! Dis na wan kayn malignant ‘Sarcoma’ (sɔft tisu kansa). we yu luk am wit maykroskכp, di sεl dεm we de fכm am de luk lεk mεlanoma, we na kansa na di skin (na dat mek dεn kכl am bak Melanoma fכ sכft pat dεm). Bɔt dis kansa nɔ kin kam na di skin, bɔt i kin kam na di sɔft tisu dɛn we de kɔba di mɔsul dɛn, di tɛndon dɛn, ɛn di jɔyn dɛn.
💬 Usay na di bɔdi dɛn tumbu ya kin apin mɔs?
כltεm (mכr dan 75%) dεn tכmכro dεm ya de apin na di lכw εkstrim dεm fכ yכng pipul dεm (20-40 ia ol). Dɛn kin apia fɔs lɛk wan lump we nɔ de pen, mɔ we de rawnd di tɛndon dɛn we de rawnd di fut, anklɛ, ɛn ni.
💬 Dis kansa denja? Yu tink se i de kil pɔsin?
Dis lump, we nɔ gɛt stem, kin rili agresiv. I de gro sloslo, so di sik pipul dεm nכ de pe atɛnshɔn to am, bכt i de spre fa fawe to di limf no dεm εn di lכng dεm (Mεtastasis). fכ dat, i implεnt fכ pul di lump kכmplit wan εn di ‘big’ εria we de rawnd am wit wan big lokal εksizishכn εn gi rεdyushכn tritmεnt.
` klia sel sarkoma, sכft tisu kansa, leg tכmכro, leg tכmכro, sarkoma, kεnsar simptom, kεnsar tritmεnt
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