Yu gɛt ɛni strenj spat ɔ lumps na yu skin? Dis kin bi Cutaneous B-Cell Lymphoma?

Wi skin na wɔndaful tin, nɔto so? Sɔntɛnde, smɔl smɔl pimples ɛn spat dɛn kin kam ɛn go. Bɔt sɔntɛnde yu kin sɔprayz smɔl bɔt nyu say ɔ bɔmp na yu skin, ɔ wan we dɔn de fɔ lɔng tɛm we nɔ wɛl. Dɛn kayn tɛm dɛn de, wi nid fɔ tek tɛm smɔl. Bikɔs, pan ɔl we i nɔ kin apin so ɔltɛm, dis kayn chenj na di skin kin bi sayn bak fɔ wan siriɔs sik. Tide wi go tɔk bɔt dis kayn sik we nɔ kin bɔku, bɔt we rili impɔtant to di skin we wi fɔ no bɔt. dat na wan kכndyushכn we dεn kכl kכtan B-sεl limfoma, כ `(Kutεn B-sεl Limfoma)`.

Wetin na Cutaneous B-Cell Lymphoma?

Fɔ tɔk am simpul wan, Cutaneous B-Cell Lymphoma (CBCL) na wan kayn kansa we kin bigin na yu skin. I de rare smɔl. I de pan wan grup we gɛt kansa we dɛn kɔl limfoma. Bɔt di spɛshal tin na dat i kin bigin na do na wi limf no dɛm, na di skin. Na dat mek dɛn kɔl am ɛkstranodal limfoma.

כltεm, dis `(CBCL)` de sho lεk spat, rash, כ lump na di skin. Dɛn tin ya kin gro sloslo. I kin tek mɔnt, ivin ia fɔ mek dɛn gro. Dɔn bak, dɛn nɔ kin skata to ɔda pat dɛn na di bɔdi. Sɔm pipul dɛn kin kɔl am bak `(B-cell skin lymphoma)`. So, if yu notis nyu tin ɔ difrɛn tin na yu skin, i go fayn fɔ pe atɛnshɔn to am.

Aw dis limfoma kin kam? Wetin na B-sɛl dɛn?

Naw yu go de wɔnda wetin mek sɔntin lɛk dis kin apin. Fɔ tɔk tru, sayɛnsman dɛn stil nɔ dɔn fɛn di rayt tin we mek dis `(CBCL)`. Bɔt wan tin klia: i nɔ kin kɔmɔt frɔm dɛn mama ɛn papa ɔ i nɔ kin pas.

I kin bigin wit wayt blɔd sɛl dɛn we dɛn kɔl limfosayt. dis limfosayt dεm na rili imכtant mεmba dεm na wi imyun sistεm. Dɛn tan lɛk di ami we de protɛkt wi kɔntri. tu men kayn limfosayt dεm de: T-sεl dεm εn B-sεl dεm. we di B-sεl dεm bigin fכ gro tu mכch we dεn nכ kכntrol, dis kכndyushכn we dεn kכl B-sεl limfoma de apin. Fɔ tɔk am simpul wan, wi yon sɛl dɛn kin kray smɔl ɛn bi kansa sɛl.

Wetin na di men kayn kכtan B-sεl limfoma?

Fo men kayn dis ``(CBCL)`` de. Dɛn kin sheb dɛn tin ya bay aw di sɛl dɛn de luk ɔnda maykroskɔp. Ɛni wan pan dɛn kin luk difrɛn na di skin ɛn dɛn kin nid fɔ gɛt difrɛn tritmɛnt dɛn.

1. Praymari kכtan fכlikul sεntr limfoma:

• Dis na di kayn `(CBCL)` we dɛn kin si mɔ.
• Bɔrku tɛm, dɛn kin apin na di ed, nɛk, ɔr chɛst/tɔrso.
• I kin tan lɛk rɛd-brawn, nodul dɛn we rayz ɔ rash na di skin .
• Dis kin rili siriɔs, i kin divɛlɔp fɔ sɔm mɔnt, sɔntɛm fɔ lɔng tɛm.

2. Praymari kutan marginal zכn B-sεl limfoma:

• Dis na wan kayn bak we de gro fayn fayn wan.
• Bɔku tɛm, i kin tan lɛk pinkish-rɛd lɛsin, nodul, ɔ tumbu .
• Bɔku tɛm i kin apin na di bɔdi ɔ di an dɛn.

3. Praymari kutan difכs big B-sεl limfoma, leg tכp:

• Dis smɔl smɔl pas di ɔda tu kayn, bɔt i kin agresiv. Dat min se i kin gro kwik kwik wan, insay sɔm wik ɔ mɔnt.
• Bɔku tɛm i kin apia lɛk wan ɔ mɔ tumbu ɔ nodul na di leg, an, ɔ chɛst/tɔso.

4. Praymari kutan difεs big B-sεl limfoma, כda wan dεm:

• Dis na wan spisis we nɔ kin bɔku ɛn we kin fɛt.
• Di we aw i tan kin difrɛn, bɔt i kin bigin na di ed, di bɔdi, ɛn di pat dɛn we de nia di bɔdi.

Udat kin gɛt dis sik pas ɔlman? Aw i kɔmɔn?

fכ tru, dis kכndyushכn we dεn kכl ``(CBCL)`` kin divεlכp pan enibodi. Nɔ difrɛns nɔ de bitwin man ɛn uman, difrɛns nɔ de pan di ej, ɛn dɛn dɔn si se i de divɛlɔp na difrɛn etnik grup dɛn. So, i at fɔ tink se, "Dis nɔ go apin to mi."

Bɔt, nɔ panik. Dis na tin we nɔ kin apin so ɔltɛm. Tink bɔt am, if yu tek avrej wan milyɔn pipul dɛn, na 4 pan dɛn nɔmɔ go gɛt dis. So, yu nɔ nid fɔ panik ɛn tink se dis na ``(CBCL)`` di tɛm we yu notis sɔntin we strenj na yu skin. Bɔt if yu gɛt ɛni dawt, i go fayn fɔ mek yu go to dɔktɔ.

Wetin na di sayn dɛm we de sho se yu gɛt dis sik? Si if yu gɛt dɛn sik ya bak

di men simptom fכ `(CBCL)` na di chenj dεm na di skin. Dɛn tin ya kin apin difrɛn we dɛn:

• Wan rash we dɛn kɔl rash
• Wan lump ɔ bɔmp na di skin
• Wan smɔl lump (nodul ɔ tumor) .

Dɛn tin ya kin bi rɛd, pepul, ɔ brawn. Sɔm dɛn kin rayz ɛn dɛn kin tayt, bɔt dɛn kin smol. Dɛn kɔl dɛn tin ya papul. Ɔda wan dɛn kin flat, lɛk pat dɛn we gɛt tik tik skin. Dɛn kɔl dɛn tin ya plek. dεn kכl bכku bכku bכku dεm bak nodul כ tכmכro.

I kin bi se na jɔs wan pan dɛn kayn ples/lɔmp de, ɔ i kin gɛt sɔm. Dɔn bak, dɛn kin apia na wan ples nɔmɔ na di bɔdi ɔ na bɔku say dɛn. Dɛn kin de nia dɛnsɛf, ɔ dɛn kin de fa frɔm dɛnsɛf.

Imajin, Ɔnkul Sunil bin gɛt wan smɔl rɛd ples na in an fɔ sɔm mɔnt. I bin tink se na jɔs skrach. Bɔt smɔl smɔl i bin de big ɛn i bin tan lɛk wan swɛlin. Na dat kin bi wan fɔs sayn fɔ dis.

Na smɔl tɛm nɔmɔ, sɔm pipul dɛn kin gɛt ɔda sayn dɛn bak. Dɛn kin kɔl dɛn tin ya bak "B simptom dɛm". Dɛn tin ya na:

• Fiva we kin kam witout rizin.
• Fɔ swet pasmak na nɛt.
• di limf no dεm na di nεk, di armpit dεm, כ di groin we de swεla.
• We yu de lɔs yu wet we yu nɔ gɛt rizin.

di prεsεns fכ dεn "B fכm" dεm min se di sik kin dכn spre sכmtεm. Bɔt dɛn tin ya nɔ kin bɔku na `(CBCL)`.

Aw dɔktɔ dɛn kin no bɔt dis?

Bɔku pipul dɛn kin delay fɔ go to dɔktɔ bikɔs di spat ɛn bɔmp dɛn we kin apia na di skin na CBCL kin tan lɛk akni ɔltɛm, insɛkt bayt, alɛji, skrat, ɔ ɔda tin dɛn we kin apin na di skin lɛk ɛkzema ɔ psoriasis. Bɔt if yu gɛt sɔntin we nɔ kɔmɔn na yu skin we nɔ de wɛl, yu fɔ rili go to dɔktɔ, mɔ to dɔktɔ we de mɛn yu skin.

Di dɔktɔ go fɔs du gud gud wan fɔ chɛk yu skin. Dɛn go luk ɔl di say dɛn na yu bɔdi ɛn asɛs fɔ ɛni abnɔmal tin.

afta dat, fכ difinitivli no di sik, dεn nid fכ du ``skin biopsy``, we min se fכ tek sכm sכm pat pan di skin frכm di abnכmal εria εn egzamin am. dis sכmכl pat pan di skin dεn de egzamin am כnda maykroskכp bay wan spεshal (``pathologist``) fכ si if eni kεnsar sεl dεm de, εn if na so, us kayn dεn bi. di ``bayopsi`` na di onli we fכ no εksakכt if na ``skin limfoma`` εn us sכbtayp i bi.

Fɔ si if di kansa dɔn skata, yu dɔktɔ kin ɔda fɔ mek dɛn du ɔda tɛst (`staging tests`). Dɛn tin ya kin bi:

• Blɔd tɛst dɛn.
• Imej tɛst dɛn lɛk CT skan ɔ PET skan.
• Bɔn mɛrɔ bayɔpsi.
• Limf node bayɔpsi.

Lɛ wi lan bɔt di stej dɛm ɛn aw di sik kin skata.

Di stej fɔ di sik (CBCL) na fɔ no if di kansa dɔn skata ɛn aw fa i dɔn skata. Dis stej rili impɔtant bikɔs na in de sho di tritmɛnt. Yu dɔktɔ go ɛksplen to yu us stej de sik ɛn aw i go afɛkt yu.

• Stej 1E: di "E" tinap fכ "ekstranodal," we min se na do na di limf no dεm. Na dis stej, di kansa kin de na di skin ɛn i nɔ dɔn spre ɔdasay. If nכ כda "B" simptom dεm de, lεk fiva כ we yu de lכs wet, dεn kin kכl dis bak "Stage 1AE."

if di ``CBCL'' dכn spre, dכkta dεn de yuz wan sistεm we dεn kכl ``TNM stej sistεm''.

• Tכmכro (T): di lεta "T" de tכk bכt di nכmba fכ di papul dεm, nodul dεm, כ tכmכro dεm na di skin, aw big dεn bi, εn usay dεn de. dis dεn nכmba frכm 1 to 3 (frכm di lεst to di mכst siriכs).
• Nod dɛn (N): .di lεta "N" de sho if di limf no dεm de afekt, כl di limf no dεm, εn usay dεn de. Dis gɛt nɔmba bak frɔm 0 to 3.
• mεtastas (M): di lεta "M" de sho if di limfoma dכn spre pas di skin כ di limf no dεm (`M1`) כ nכ (`M0`). `(Mεtastasis)` min se di kansa dεn dכn spre to di כgan dεm we de fa.

Wetin na di tritmɛnt dɛn? Yu tink se dɛn kin mɛn am?

Tritmεnt fכ `(CBCL)` dipכnt pan di sכbtayp εn stej fכ di sik. Bɔku tɛm, dɛn kin mɛn am, mɔ pan di wan dɛn we dɔn go bifo. Bɔt sɔmtɛm di sik kin `rikɔr`.

Bɔku tritmɛnt dɛn de we yu kin pik:

• Aktiv sɔvɛlayshɔn: Insay sɔm kes dɛm we di sik de gro ɛn nɔ de kɔz ɛni big prɔblɛm, dɔktɔ dɛn kin tek "watch ɛn wet" we. Dat min se dɛn kin wach di sik te dɛn bigin fɔ trit am.
• Kimotɛrapi: Fɔ gi mɛrɛsin dɛn we de kil kansa sɛl dɛn. Dɛn kin tek dɛn tin ya as pils ɔ gi dɛn as injɛkshɔn.
• Mεdikeshכn dεm we dεn kin tek כ injεkt: Yu kin put mεdikeshכn dεm lεk kכtikostεroyd pan di skin כ injεkt dεm dairekt insay di lump.
• Monoclonal antibodies: Drug dεm lεk `(Rituximab)` de insay dis grup. dis dεm de wok lεk tεrapi dεm we dεn de tכk bכt εn dεn de pwεl di B-sεl dεm.
• Radieshɔn tɛrapi: Na di we aw dɛn de yuz rayt we gɛt bɔku ɛnaji fɔ pwɛl di kansa sɛl dɛn. dis kin wok bכku tεm fכ lokalizεd tכmכro dεm.
• Ɔpreshɔn fɔ pul am: Sɔntɛnde, if wan lump de, dɛn kin pul am kpatakpata wit ɔpreshɔn.

Yu dɔktɔ go tɔk to yu bɔt di tritmɛnt we go fayn fɔ yu.

Yu tink se we de fɔ mek dis nɔ apin?

Na ɔnfɔni, bikɔs dɛn stil nɔ no di rayt kɔz fɔ `(CBCL)`, no pruf nɔ de fɔ mek i nɔ apin. So, di bɛst tin we wi go du na fɔ no ɛni chenj we nɔ kɔmɔn na wi skin ɛn go to dɔktɔ wantɛm wantɛm if wi notis ɛnitin.

Wetin na di prɔgnosis? (Prɔgnosis) .

Di prɔgnosis ɔ aw yu go si am, kin dipen pan sɔm tin dɛn, mɔ di kayn limfoma ɛn di stej we di sik de.

• di tu tכp dεm we kכmכn pas כl (`Primary cutaneous follicle center lymphoma` εn `Primary cutaneous marginal zone B-cell lymphoma`): dεn ya gεt fayv ia sכvayv rεt we na lεk 95%. Dat min se fayv ia afta dɛn dɔn no se dɛn gɛt di sik, 95 pan ɔl 100 pan dɛn sik pipul ya stil de alayv. Dis na tin we rili fayn fɔ du.
• di tכp dεm we de agresiv mכst (`Primary cutaneous diffuse large B-cell lymphoma, leg type` εn `other`): dεn wan ya gεt fayv ia sכvayv rεt we na lεk 60%.

Dɛn nɔmba dɛn ya na jɔs avrej. Yu situeshɔn kin bɛtɛ ɔr wɔs, so i bɛtɛ fɔ tɔk to yu dɔktɔ bɔt dis.

A kin kam bak afta dɛn dɔn trit mi?

Yɛs, cutaneous lymphoma kin kam bak afta dɛn dɔn trit am. Di lumps kin kam bak na di sem ples ɔ na nyu ples. Bɔku tɛm, di sem sɔbtayp kin kam bak. Bɔt, na smɔl tɛm nɔmɔ, CBCL we dɔn kam bak kin bi sistɛm sik ɔ ɔda kayn limfoma.

So, i rili impɔtant fɔ de chɛk yu skin ɔltɛm (`skin checks`) ɛn de chɛk-ap ɔltɛm wit dɔktɔ we de mɛn yu skin ɔ ɔda spɛshal pɔsin.

Aw yu kin tek kia ɔf yu wɛlbɔdi as pɔsin we gɛt CBCL?

If yu gɛt (CBCL) ɔ yu dɔn gɛt am bifo ɛn yu dɔn wɛl, i rili impɔtant fɔ fala yu dɔktɔ in instrɔkshɔn. Yu go nid fɔ kɔntinyu fɔ du tɛst fɔ mek shɔ se di sik nɔ kam bak.

Aw ɔltɛm dɛn kin du dɛn tɛst ya go difrɛn difrɛn wan bay di kayn CBCL ɛn aw i agresiv. I kin bi ɛvri sɔm wik, ɛvri sɔm mɔnt, ɔ wan tɛm insay di ia. Dɛn fɔlɔp apɔntinmɛnt ya kin inklud fɔ tɛst yu skin, blɔd tɛst, ɛkstrem rayt, ɔ bayɔpsi.

Kwɛstyɔn dɛn we yu fɔ rili aks yu dɔktɔ

If dɛn no se yu gɛt `(Cutaneous B-Cell Lymphoma)`, nɔ fɔgɛt fɔ aks yu dɔktɔ dɛn kwɛstyɔn ya:

• Us `(CBCL)` sabtayp a gɛt?
• Us stej dis de insay?
• Us kayn tritmɛnt yu kin advays?
• Wetin na di sayd ɛfɛkt ɛn risk dɛn we dɛn tritmɛnt dɛn de gɛt?
• Wetin na mi prɔgnosis?
• Aw lɔng i kin tek fɔ no if di tritmɛnt dɔn wok fayn ɔ nɔ go wok fayn?
• Aw ɔltɛm a fɔ si yu fɔ mek shɔ se di limfoma nɔ kam bak?

Di ansa to dɛn kwɛstyɔn ya go ɛp yu fɔ ɔndastand di sik ɛn di nɛks tin dɛn we yu fɔ du.

Take-Home Message frɔm Wetin Wi Dɔn De Tɔk Bɔt

Cutaneous B-Cell Lymphoma na wan kayn kansa we nɔ kin apin so ɔltɛm we kin bigin na sɛl dɛn we dɛn kɔl limfosayt na di skin.

• Bɔrku pan di kes dɛm kin gro sloslo ɛn nɔr kin spre to ɔda pat dɛm na di bɔdi. Bɔt sɔm kayn dɛn kin bi agresiv ɛn skata.
• If yu notis nyu bɔmp, spat, ɔ rash na yu skin we nɔ de wɛl , nɔ ignore am. Go to dɔktɔ, mɔ to dɔktɔ we de mɛn di bɔdi, wantɛm wantɛm.
• Bɔku kayn CBCL kin wɛl if dɛn no am kwik ɛn trit am fayn.
• Bikɔs di sik kin kam bak afta dɛn dɔn trit am, .I impɔtant fɔ mek dɛn du tɛst di tɛm we dɛn dɔn plan fɔ du lɛk aw di dɔktɔ tɛl yu fɔ du am.

Mɛmba se dis infɔmeshɔn na fɔ ɛdyukeshɔn nɔmɔ. If yu gɛt ɛnitin fɔ wɔri bɔt yu wɛlbɔdi biznɛs, i go fayn fɔ mek yu go to dɔktɔ.

` Kutan B-Sεl Limfoma, Skin Kansa, Limfoma, B-Sεl, Skin Lכmp, Skin Sik