If yu na mama we go bi mama, yu kin dɔn fred smɔl we yu yɛri di wɔd dɛn ‘Erythroblastosis Fetalis’. Ɔ sɔntɛm yu dɔktɔ bin tɔk bɔt am smɔl tɛm bifo we i bin de tɔk bɔt yu blɔd tayp. I kin mek pɔsin fred smɔl fɔ yɛri dis nem. Bɔt nɔ wɔri, tide wi go tɔk bɔt am na simpul we we yu go ɔndastand. Lɛ wi si wetin na in, wetin mek i kin apin, ɛn aw wi go protɛkt wisɛf frɔm dis sik.
Wetin na ‘Erythroblastosis Fetalis’?
Fɔ tɔk am simpul wan, dis na tin we nɔ kin apin so ɔltɛm, we min se nɔto ɔlman kin gɛt am, kɔmplikeshɔn we kin apin we uman gɛt bɛlɛ. Dis kin apin if blɔd tayp nɔ gri bitwin yu ɛn yu pikin we yu nɔ bɔn yet. Nɔto ɔl di difrɛns pan di kayn blɔd kin mek prɔblɛm. כltu, dis risk de hכy spεshal if yu bכdi tכp na `Rh-negative` εn yu pikin in bכdi tכp na `Rh-positiv`.
Imajin, if yu bin gɛt dis Rh-positiv blɔd, ilɛksɛf na di tɛm we yu bin gɛt bɛlɛ bifo ɔ we dɛn bin de gi yu blɔd, di imyun sistɛm na yu bɔdi (di sistɛm we de protɛkt wi frɔm sik dɛn) kin bigin fɔ atak di pikin in rɛd blɔd sɛl dɛn. I tan lɛk se i de atak ɛnimi. Dis kin mek di pikin in rɛd blɔd sɛl dɛn go dɔŋ bad bad wan. Wi kin kɔl dis anemia. If dis anemia kam tranga, i kin mek di pikin day if dɛn nɔ trit am.
Bɔt gud nyus de! Dis tɛm ya, we yu kin du tɛst ɔltɛm we yu gɛt bɛlɛ, dat kin mek yu no di kayn blɔd we yu gɛt. If yu na Rh-negative, dɔktɔ kin gi yu mɛrɛsin fɔ mek yu nɔ gɛt dis prɔblɛm.
dis kכndyushכn dεn kכl am bak `(alloimmune hemolytic disease fכ di nyu bכbi - HDN)` εn `(hεmolytic sik fכ di pikin εn nyu bכbi - HFDN)`. bכt we wi de tכk bכt am, wi go yuz di tεm `(Erythroblastosis Fetalis)`.
Wetin na di sayn dɛm if di pikin gɛt dis sik?
di pikin dεm we dεn bכn wit dis kכndyushכn (Erythroblastosis Fetalis) kin sho sayn dεm fכ anemia. Sɔm pikin dɛn kin gɛt am saful wan, ɛn ɔda wan dɛn kin gɛt am bad bad wan. Dɔn bak, di pikin kin gɛt janda insay 24 awa afta dɛn bɔn am. Na sɔm pan di sayn dɛm wae de sho se yu gɛt dis sik:
- Di yay ɛn di skin we de yɔlɔ.
- Di skin kin pale wantɛm wantɛm .
- di pikin kin fil bכku bכku wan εn i nכ gεt layf (lethargy).
- Di at de bit fast fast (tachycardia).
- Nɔ gɛt apɛtit fɔ milk.
insay sכm siriכs kes dεm, di pikin כ di nyu bכbi kin gεt wan kכndyushכn we de mek i in layf de pan denja we dεn kכl ``hydrops fetalis.'' in simptom dεm na:
- Di bɔdi we de swel.
- di wata we de kכmכt na di pikin in bεlε, כ bitwin di imכtant כgan dεm lεk di at εn di lכng dεm.
Wetin mek dis de apin? Wetin na di rizin dɛn?
dis kכndyushכn we dεn kכl ``Erythroblastosis Fetalis'', de apin biכs, lεk aw wi bin dכn tכk, yu bכdi in imyun sistεm de atak di pikin in rεd bכdi sεl dεm.
Wi rɛd blɔd sɛl dɛn gɛt spɛshal mak dɛn pan dɛn. Wi kכl dεm ``antijen.'' Tink bכt dεn ``antijen'' ya lεk lεbul dεm we gεt nem pan dεm. If yu imyun sistɛm no dis lɛbl, i nɔ go atak dɛn rɛd blɔd sɛl dɛn de.
Dis na bikɔs ɔf di difrɛns pan yu ɛn yu pikin in blɔd tayp. di kayn bכdi dεm dεn kin kכl dεm bay di ``antijen`` dεm we de na di sεf fכ di rεd bכdi sεl dεm. Tu men kayn blɔd de we wi de tɔk bɔt:
- Rh factor: Dis min if di bכdi na positifu (+) כ nεgεtiv (-).
- ABO antijen dεm: Dis min se A, B, AB, כ O bכdi tכp.
if yu bεlε, yu imyun sistεm, if i nכ no di ``antijen`` dεm na yu pikin in rεd bכdi sεl dεm, go bigin fכ mek ``antibodi`` agens dεm. dis ``antibodi`` dεm na dεn de atak dεn rεd bכdi sεl dεm. Jɔs lɛk we wi bɔdi gɛt wan jem we de mek wi sik, na so wi bɔdi kin fɛt am. Bɔt fɔ mek dis apin, di pikin in blɔd fɔ kam nia yu blɔd. Bɔku tɛm, dis kin apin we di pikin de kam bɔn. Bɔt sɔntɛnde, di blɔd kin miks wit am bifo. Fɔ ɛgzampul:
- If dɛn pwɛl bɛlɛ.
- if di bεlε lכs haf, dεn kכl am ``Miscarriage``.
- insay wan situeshכn lεk εktopik bεlε (di bεlε de na do na di uterus, lεk na di fallopian tכb).
- we dεn de du ``(Amniocentesis)`` (tεst we dεn de du we uman bεlε).
- We yu de du `(Chorionic villus sampling)` (ɔda bɛlɛ tɛst).
we yu bכdi dכn prodyuz dεn `(antibodi dεm)` ya, i de mεmba am. if di pikin in rεd bכdi sεl dεm gεt da `(antijen)` de bak insay di nεks bεlε, dεn `(antibodi)` dεm go go pwεl dεn sεl dεm. wi kכl dis dεstrukshכn fכ di rεd bכdi sεl dεm `(hεmolysis)`.
Men kɔz: Rh inkɔmpatibiliti
di mכst siriכs εn we dεn no gud gud wan fכ dis kכndyushכn na we yu gεt Rh-nεgεtiv εn yu pikin gεt Rh-positiv. we dis apin, yu imyun sistεm de atak yu pikin in Rh-positiv rεd bכdi sεl dεm. Insay kɔntri lɛk Amɛrika, lɛk 15% pan pipul dɛn gɛt Rh-nɛgitiv blɔd. Bɔku tɛm, di mama ɛn di papa, ɛn di pikin ɔl tu kin gɛt Rh-positiv.
כltu, dis Rh inkompatibiliti nכ de kכz nכ big prכblεm di fכs bεlε. ivin if yu na Rh-nεgεtiv εn di pikin na Rh-positiv, i nכ kin izi fכ yu bכdi miks wit di pikin in bכdi we i bεlε fכ mek i gεt siriכs riakshכn (antibodi dεm). Bɔt we dɛn dɔn bɔn di pikin, yu blɔd go mɔs riak wit di pikin in blɔd. Da tɛm de, if yu nɔ tek mɛrɛsin fɔ mek yu imyun sistɛm nɔ atak am, yu bɔdi kin gɛt antibodies agens di Rh-positiv rɛd blɔd sɛl dɛn.
Dɔn if yu gɛt bɛlɛ bak, ɛn da pikin de gɛt Rh-positiv blɔd tayp bak, dɛn antibodi dɛn we dɛn bin dɔn mek bifo tɛm go go atak da pikin de in rɛd blɔd sɛl dɛn. Yu ɔndastand?
Ɔda blɔd tayp we nɔ kin apin so ɔltɛm
Sɔntɛnde, yu imyun sistɛm kin atak yu pikin in rɛd blɔd sɛl dɛn pan ɔl we i nɔ gri wit wan rɛd blɔd sɛl antijen we nɔ kin bɔku. dis kin apin if yu pikin gεt da rare antijen de εn yu lכs am. Dis kin apin if yu dɔn gɛt da antijen de tru wan bɛlɛ we yu bin dɔn gɛt ɔ we yu bin dɔn gi yu blɔd ɛn yu dɔn gɛt antibodi dɛn fɔ am. Sɔm pan dɛn antijen ya na:
- `(Kɔltɔn)`
- `(Dafy)`
- `(Diego)`
- `(Ee)`
- `(Gɛbich)`
- `(H)`
- `(Kɛl)`
- `(Kid)`
- `(Lutheran)`
- `(MNS)`
- `(P)`
- `(Xg)`
di bכdi tεst dεm we dεn du ali we yu bεlε kin no if yu de mek antibodi dεm fכ dεn kayn rεd bכdi sεl dεm ya we nכ kin apin.
Aw dis sik kin kɔmɔn?
כlsay na di wכl, dεn ripot se lεk 276 pan 100,000 pikin dεm we dεn bכn layf layf wan gεt bεlε kכmplikεshכn dεm we kכl Rh bכdi tכp inkompatibiliti. di wan dεm we de du risach se if dεn nכ trit am, 50% chans de fכ di pikin we de na in bεlε go day כ gεt siriכs hεlth prכblεm.
Bɔt nɔ wɔri! If dɛn de tɛst di blɔd tayp ɛn di mɛrɛsin we dɛn nid, dɛn kin avɔyd di bad tin dɛn we kin apin. na sɔm pat dεm na di wכl usay dεn de kia fכ di pikin bifo dεn bכn, na כnli lεk 2.5 pan 100,000 pikin dεm we dεn bכn gεt prכblεm biכs fכ Rh inkכmpatibiliti. Dis na big tin we de mɔna pipul dɛn na Sri Lanka bak.
Aw yu kin fɛn dis?
כltεm, na klinik dεm we de bifo bכn, dεn de chεk yu bכdi tכp εn eni ``antibodi''. if yu bεlε εn yu gεt Rh-nεgεtiv bכdi tכp, yu dכkta go chεk fכ ``antibodies'' εgεst Rh-positiv bכdi. if yu nכ gεt dεn ``antibodi'' dεm, dεn go gi yu imyun sistεm mεdisin fכ stכp dεm fכ fכm.
if di tεst kכnfכm se yu gεt dεn antibodi dεm ya, i min se if di pikin gεt Rh-positiv, yu imyun sistεm de pan risk fכ atak di pikin in rεd bכdi sεl dεm. Dɔn yu dɔktɔ go chɛk yu antibodi lɛvɛl ɛvri sɔm wik. If yu antibodi lɛvɛl denja, dɛn kin du ɔda tɛst fɔ si if yu pikin gɛt anemia, ɛn yu kin nid fɔ tek blɔd na di bɛlɛ. If yu pikin de pan denja fɔ bɔn wit siriɔs anemia, yu dɔktɔ kin disayd fɔ bɔn di pikin kwik kwik wan.
Afta di pikin dɔn bɔn, di dɔktɔ kin no di pikin in blɔd. Dis kin ɛp fɔ no if di pikin in anemia na bikɔs di blɔd tayp nɔ gri wit am.
Ɔda tɛst dɛn we dɛn kin du na:
- Kɔmplit Blɔd Kɔnt (CBC): Dis tɛst kin chɛk aw di pikin in rɛd blɔd sɛl dɛn smɔl. Di mɔ di lɛvɛl we di lɛvɛl de dɔŋ, na di mɔ di anemia kin rili bad.
- Peripheral Blood Smear (PBS): Dis na fɔ chɛk blɔd sɛmpul ɔnda maykroskɔp. dis kin gi wan aidia fכ if di dכn na di dכn we di rεd bכdi sεl dεm de pwεl bifo tεm (hεmolysis).
- Bilirubin tɛst: .Dis de mekɔp di bilirubin lɛvɛl. Bilirubin na bayprodukt we de mek di rɛd blɔd sɛl dɛn brok. If yu gɛt ay bilirubin (hyperbilirubinemia) i kin sho se dɛn de pwɛl di rɛd blɔd sɛl dɛn.
- Dairekt Antiglobulin Tεst (DAT): Dis tεst de sho if antibodi dεm de na di pikin in rεd bכdi sεl dεm. dis min se di mama in imyun sistεm de atak di pikin in sεl dεm.
Wetin na di tritmɛnt dɛn?
Di tritmɛnt dipen pan if yu gɛt bɛlɛ ɔ yu jɔs bɔn pikin.
Di tritmɛnt we dɛn kin gi we uman gɛt bɛlɛ
If yu gɛt antibodi dɛm we de put yu pan risk fɔ Erythroblastosis Fetalis, yu dɔktɔ go wach yu antibodi lɛvɛl ɛvri sɔm wik. If yu antibodi lɛvɛl bɔku, yu kin nid fɔ du ɔda ɔltra saund skan fɔ si if yu pikin gɛt blɔd. If di anemia bad bad wan, yu pikin kin nid fɔ gɛt blɔd.
Tritmɛnt afta dɛn bɔn di pikin
dכkta dεn kin trit nyu bכbi dεm wit ``Erythroblastosis Fetalis'' bay we dεn de trit anemia εn ``hyperbilirubinemia'' (jaundice). Di tritmɛnt dɛn we yu kin pik na:
- Fɔtotɛrapi: Dis kin yuz layt fɔ trit di haypa bilirubinemia. dis layt de kכnvכlt bilirubin to tin dεm we izi fכ kכmכt na di pikin in bכdi.
- Blɔd transfyushɔn: Afta di pikin dɔn bɔn, di pikin kin nid fɔ gɛt blɔd fɔ mek shɔ se i gɛt inof rɛd blɔd sɛl.
- Erythropoiesis Stimulating Agents (ESA): Dɛn tin ya kin bi opshɔn fɔ trit anemia we nɔ bad fɔ mek dɛn nid fɔ transfyushɔn blɔd. Dɛn kin nid fɔ gi dɛn wit ayɔn sɔpɔtmɛnt fɔ ɛp di pikin fɔ mek wɛlbɔdi rɛd blɔd sɛl dɛn.
If i siriɔs, di pikin kin nid sɔpɔt fɔ kia fɔ am, lɛk ventilator ɛn IV fluid.
Wetin kin apin to di pikin afta dis situeshɔn?
Di rizulyt dipכnt pan aw yu pikin in sik dεm de tranga. Siriɔs anemia ɛn haypa bilirubinemia kin kil pɔsin if dɛn nɔ trit am.
כltu, pikin dεm we gεt Erythroblastosis Fetalis kin liv di kכndyushכn if dεn trit dεm fayn fayn wan. Dɛn kin nid fɔ gi dɛn blɔd fɔ mek dɛn gɛt bɔku rɛd blɔd sɛl dɛn we dɛn gɛt bɛlɛ ɛn/ɔ afta dɛn bɔn dɛn. Di dɔktɔ go nid fɔ wach dɛn fɔ sɔm mɔnt fɔ mek shɔ se no prɔblɛm nɔ de.
Yu nɔ tink se dɛn go ebul fɔ stɔp dis?
I rili pɔsibul! εrythroblastosis Fetalis kin bכku bכku wan tru bכdi tεst εn mεdikeshכn fכ prεvεnt we uman bεlε.We aw tin bi naw. If yu na Rh-negativ, yu kin tek Rh immune globulin (Rh immune globulin - RhIg ɔ RhoGAM®) fɔ mek yu bɔdi nɔ mek antibodies agens Rh-positiv blɔd. Yu nid fɔ tek dis mɛrɛsin we yu gɛt 28 wiks we yu gɛt bɛlɛ, insay 72 awa afta di bɛlɛ dɔn (afta yu bɔn, yu gɛt bɛlɛ), ɛn if yu gɛt bɔku blɔd we yu gɛt bɛlɛ (ivin insay di fɔs tri mɔnt).
Dis kin wok if yu tek dis mɛrɛsin bifo yu blɔd de pan Rh-positiv blɔd. Na dat mek dɛn kin luk am mɔ na di klinik dɛn we uman kin gɛt bɛlɛ.
Tin dɛn fɔ aks yu dɔktɔ
If yu gɛt ɛni ɔda kwɛstyɔn bɔt dis, nɔ fred fɔ aks yu dɔktɔ ɔ nɔs. Na sɔm ɛgzampul dɛn ya:
- Wetin na mi blɔd tayp?
- Eni ``antibodies'' de we a fɔ wɔri bɔt?
- A fɔ wɔri bɔt `(Erythroblastosis Fetalis)`?
- A go nid fɔ gɛt ɔda monitarin ɔ fɔ go na di klinik ɔltɛm?
- A go nid fɔ tek Rh imyun globulin (RhIg)?
- Ustɛm a fɔ mek apɔntinmɛnt ɔ fɔ go fɛn pɔsin fɔ kia fɔ mi kwik kwik wan?
Wetin kin apin if di mama gɛt Rh-positiv ɛn di pikin gɛt Rh-negativ?
Dis nɔr kin bi wan kayn blɔd we nɔr kin gri wit wetin yu fɔ wɔri bɔt. Rh-nεgεtiv pikin nכ gεt di Rh-antijen we di mama in imyun sistεm kin atak. If ɔda blɔd tayp we nɔ kin apin so ɔltɛm de, dis nɔ fɔ bi prɔblɛm.
Di tin dɛn we impɔtant pas ɔl we wi fɔ mɛmba
Di aidia se yu yon imyun sistɛm kin atak yu pikin we nɔ bɔn yet na sɔntin we de mek yu fred. Bɔt di gud nyus na dat, dɛn denja we blɔd nɔ kin gri wit dɛnsɛf nɔ kin bɔku. Ɛn, dɔktɔ dɛn kin du dɛn bɛst fɔ mek dɛn prɔblɛm ya nɔ apin. Blɔd tayp tɛst na sɔntin we dɛn fɔ du fɔ kia fɔ pikin bifo dɛn bɔn pikin. Dɔn bak, fɔ wach ɛn trit di blɔd tayp inkɔmpatibiliti we kin mek yu pikin de pan denja na pat we dɛn dɔn establish fɔ kia fɔ di pikin bifo i bɔn. Yu dɔktɔ go de wit yu ɛvri step fɔ mek yu ɛn yu pikin sef. So, nɔ panik we yu nɔ nid, ɛn fala di dɔktɔ in instrɔkshɔn dɛn gud gud wan. Dɔn yu ɛn yu pikin ɔl tu go ebul fɔ gɛt wɛlbɔdi!
` Erythroblastosis Fetalis, Rh inkompatibiliti, bεlε komplikashכn, pikin in bכdi tכp, mama in bכdi tכp, anemia, janda, RhoGAM
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