Wetin na di sik we dɛn kɔl Evans Syndrome? Lɛ wi tɔk bɔt am!

Sɔntɛnde, yu kin fil taya? Ɔ i nɔ kin izi fɔ yu fɔ stɔp fɔ blɔd ivin frɔm di smɔl smɔl tin dɛn? Sɔntɛm na bikɔs yu bɔdi in imyun sistɛm de wok agens yu. Tide wi go tɔk bɔt dis kayn tin we nɔ kin apin so ɔltɛm bɔt we rili impɔtant fɔ no bɔt. Dat na di sik we dɛn kɔl Evans Syndrome . Nɔ wɔri, wi go tɔk bɔt ɔltin insay simpul wɔd dɛn.

So, wetin na Evans Syndrome?

Fɔ tɔk am simpul wan, Evans Syndrome na wan sik we pɔsin kin gɛt we i de fɛt insɛf . Wetin kin apin na dat di sojaman dɛn we fɔ protɛkt wi bɔdi, we na di imyun sistɛm, kin mistek bigin fɔ pwɛl sɔm pan wi yon blɔd sɛl dɛn. I tan lɛk se wi yon ami de atak wi yon pipul dɛn. Dis kin mek wi bɔdi lɔs di blɔd sɛl dɛn we wi nid. Dis abnכmal dεkrεshכn na di bכdi sεl dεm na wetin wi kכl saytopenia na mεdikal.

Bɔrku pipul dɛm wae gɛt Evans Syndrome kin fɔs afɛkt wae dɛn gɛt low red blood cells (wan tin wae dɛn kɔl anemia ) ɛn platelet (wan tin wae dɛn kɔl thrombocytopenia ). Apat frɔm dɛn tu tin ya, sɔm pipul dɛn kin gɛt smɔl nɔmba bak pan wan kayn wayt blɔd sɛl we dɛn kɔl nyutrofil (wan sik we dɛn kɔl nyutropenia ).

We dɛn kayn blɔd sɛl ya nɔ bɔku, bɔku impɔtant tin dɛn na wi bɔdi, lɛk fɔ gɛt ɔksijɛn, fɔ blɔd, ɛn fɔ fɛt sik, kin afɛkt. Na dat mek wi kin fil wik, taya, bigin fɔ blɔd izi wan, ɛn sik bɔku tɛm .

Dis sik kin afɛkt sɔm pipul dɛn bad bad wan, ɛn ɔda wan dɛn kin rili bad. Ɛn di tin dɛn we i kin du nɔ kin las di sem we fɔ lɔng tɛm. Di bɛst tin na dat , pan ɔl we no mɛrɛsin nɔ de fɔ am, tritmɛnt kin ɛp fɔ kɔntrol di sik dɛn ɛn fɔ mek i nɔ gɛt bɔku prɔblɛm dɛn .

Wetin na de sayn dɛm wae de sho se yu gɛt Evans Syndrome?

De sayn dɛm fɔ Evans Syndrome kin difrɛn bad bad wan. I dipen pan us kayn saytopenia yu gɛt ɛn aw i siriɔs. Bɔku tɛm, anemia ɔ trombocytopenia kin apin fɔs, ɛn di ɔda wan dɛn kin apin leta.

Di fɔs sayn dɛn we kin sho se pɔsin nɔ gɛt bɛtɛ rɛd blɔd sɛl ( anemia ):

Yu taya ivin afta yu dɔn waka fɔ shɔt tɛm? Yu de fil taya ɛn yu nɔ ebul fɔ du di tin dɛn we yu bin de du trade? Sɔntɛm yu fes de luk lɛk se i dɔn pale smɔl. Dis na sɔm pan di fɔs sayn dɛm we de sho se pɔsin nɔ gɛt bɛtɛ blɔd :

• Jɔs fil fɔ taya pasmak .
• Pale skin (pallor) .
• Layt ed ɔ diziz .
• I nɔ izi fɔ blo (dyspnea) .
• Fast at bit (tachycardia) .
• Fɔ fil ɔ fil lɛk se yu at de bit abnɔmal wan (at de bit) .

Di fɔs sayn dɛm we de sho se pɔsin nɔ gɛt bɛtɛ pletlɛt (thrombocytopenia):

Yu dɔn notis se sɔntɛnde, smɔl smɔl rɛd dɔt dɛn kin apia na yu skin? Ɔ yu jɔs gɛt brus ɔlsay na yu bɔdi? Yu kin fil lɛk se yu gam de blɔd pas aw yu kin blɔd we yu de brus yu tit? Dis na di sayn dɛm we pɔsin kin gɛt we i nɔ gɛt bɛtɛ pletlɛt:

• Smɔl smɔl rɛd blɔd spat dɛn (petechiae) ɔnda di skin.
• Pepul spat dɛn na di skin (purpura) .
• Brus (ecchymosis) we kin apin we nɔ gɛt ɛni rizin.
• Blɔd we de kɔmɔt pasmak na di gɔm ɔ di nos.
• Ebi blɔd we de kɔmɔt we uman dɛn de gɛt mɔnt.
• Blɔd we de kɔmɔt wit stɔl ɔ urine.

Di sayn dɛm fɔ nyutropenia (dɛn kin apin ɔ nɔ kin apin leta):

Na nɔmal tin fɔ mek yu gɛt wan ɔ tu kol insay di mɔnt. Bɔt bɔku tɛm yu kin sik wit fiva? Yu kin gɛt mɔt sos ɔltɛm? I tan lɛk se dɛn kin tek lɔng tɛm fɔ mek dɛn wɛl? Na sɔm tin dɛn we kin apin we yu nyutrofil dɛn smɔl:

• Fiva.
• Ɔlsa na yu mɔt .
• Kɔl, fiva, ɛn bɛlɛ kin at ɔltɛm.
• Infεkshכn we de kam bak na yu yes.
• Fɔŋs infɛkshɔn dɛn we kin de fɔ lɔng tɛm.
• Urinary tract infεkshכn (UTI) .

Ɔda sayn dɛm fɔ Evans Syndrome (dεn kin apin wan wan tɛm):

• Di limf no dɛm we dɔn swel na di nɛk.
• Di splin we dɔn big .
• Liva we dɔn big .
• Jandis .

Wetin mek Evans Syndrome kin apin?

As wi bin dɔn tɔk, Evans Syndrome na wan sik we pɔsin kin gɛt we i de fɛt insɛf . dis min se wi bכdi in imyun sistεm de mistek no sכm pan wi כwn bכdi sεl dεm as "εnεmi" εn bigin fכ atak dεm.

dis wok na di B sεl dεm, we na wan spεshal kayn sεl na wi imyun sistεm de du am. Dɛn B sɛl dɛn ya kin mek sɔntin we dɛn kɔl antibodi . Dɛn antibodi dɛn ya kin go ɛn kech dɛn inosɛnt blɔd sɛl dɛn de ɛn pwɛl dɛn. Bɔku tɛm, dɛn kin bigin fɔ atak wan kayn blɔd sɛl fɔs, dɔn dɛn kin bigin fɔ atak ɔda kayn blɔd sɛl dɛn.

dis prכsεs na in kin mek yu gεt dεfichεns pan at le tu kayn bכdi sεl dεm (cytopenia), εn sכmtεm dεn tri. Wan tin we nɔ de pan ɔl tri tin dɛn, dɛn kɔl am pancytopenia . Di tri men tin dɛn we kin mek dɛn blɔd sɛl ya nɔ bɔku na:

• Awtoimyun ɛmolaytik anemia (AIHA) .: Dis na we di rεd bכdi sεl dεm de rεdכks. Dat min se dɛn kin pwɛl dɛn kwik kwik wan pas aw di bɔdi kin mek dɛn.
• Immune thrombocytopenia (ITP) : Dis na di kכndyushכn we di pletlet dεm de dכn. di imyun sistεm de atak εn pul di pletlεt dεm na di bכdi.
• Autoimmune neutropenia (AIN) : Dis na di kכndyushכn we di nכmba fכ nyutrofil dεm, we na wan kayn wayt bכdi sεl, de dכn. di imyun sistεm de atak εn pwεl di nyutrofil dεm.

Tink bɔt am, bɔku rizin kin de fɔ mek di blɔd sɛl nɔ bɔku (saytopenia). Sɔntɛnde i kin bi bikɔs di bon mɛro nɔ de mek inof blɔd sɛl. Bɔt insay ɔtoimyun saytopenia, di imyun sistɛm kin pwɛl in yon blɔd sɛl dɛn.

Wetin na de tin wae kin mek yu gɛt Evans Syndrome?

Sayɛnsman dɛn stil nɔ no bɛtɛ bɛtɛ wan wetin mek dɛn sik ya we dɛn kin gɛt we dɛn de fɛt dɛnsɛf. Bɔt dɛn dɔn si se bɔku tɛm dɛn sik ya kin bigin afta pɔsin gɛt siriɔs sik ɔ sɔntin we kin mek di bɔdi strɛs bad bad wan. Dɛn kɔl dɛn tin ya trig .

Dɔn bak, if yu gɛt wan sik we de mek yu nɔ ebul fɔ fɛt, yu go gɛt ɔda wan we yu kin gɛt. I tan lɛk se dis imyun sistɛm disɔda de skata frɔm wan pat na di bɔdi to ɔda pat.

Evans syndrome kin apin in wan (dεn kכl dis praymar Evans syndrome ), כ i kin apin as sεkכnd kכndyushכn we gεt כda kכndyushכn (dεn kכl dis sεk כnd Evans syndrome) . Sɔm pan de kɔndishɔn dɛm wae kin gɛt fɔ du wit dis kayn wae na:

• Sistεmik lupus εrytematosus (lupus) .
• Kכmכn vεriεbul imyun dεfisiεns
• Selektiv IgA dɛfisiɛns
• Di sik we dɛn kɔl Sjögren in sindrom
• Limfoma we nɔto Hɔdgkin
• Kronik limfosaytik lukimiya
• Epataytis C we nɔ de mɛn
• HIV infɛkshɔn we nɔ de dɔn

If yu gɛt praymari Evans syndrome, e kin dɔn kam afta yu sik fɔ sɔm tɛm, ɔr yu nɔr kin gɛt klia trig. Sayɛnsman dɛn kin kɔl Evans syndrome as idiopathic kɔndishɔn. Dis min se dɛn nɔ dɔn fɛn ɛni dairekt kɔz.

Wetin na de prɔblɛm wae kin kam wit Evans Syndrome?

Nɔto ɔlman wae gɛt Evans Syndrome go gɛt kɔmplikeshɔn. Sɔm pipul dɛn kin jɔs gɛt sɔm kayn sik wae nɔr kin pasmak. Bɔt if i rili bad, dɛn blɔd sɛl ya we nɔ de (cytopenias) kin mek pɔsin in layf de pan denja. Fɔ ɛgzampul:

• We di rɛd blɔd sɛl dɛn nɔ de fɔ kɛr ɔksijɛn go na di bɔdi, ɔksijɛn nɔ de na di blɔd (hypoxemia) . Dis kin tranga pasmak pan de hat ɛn kin mek yu gɛt at sik ɛn at pwɛl.
• We yu nɔ gɛt inof pletlɛt , we de ɛp yu blɔd fɔ klɔt, yu blɔd nɔ de klɔt fayn. Dis kin mek yu blɔd izi ɛn kwik. Dis kin mek yu gɛt siriɔs anemia kwik kwik wan.
• We yu bɔdi lɔs nyutrofil , we de ɛp fɔ fɛt di infɛkshɔn, yu kin gɛt infɛkshɔn mɔ ɛn mɔ, ɛn i kin rili bad ɛn i kin skata ɔlsay na yu bɔdi. Dis kin mek yu gɛt wan bad bad sik we dɛn kɔl sɛpsis .

Aw dɔktɔ dɛn kin no se pɔsin gɛt Evans Syndrome?

Dɛn kin no di sik we dɛn kɔl Evans Syndrome bay we dɛn de du blɔd tɛst . Dɛn kin no am if yu gɛt sayn dɛn fɔ saytopenia, ɔ we dɛn de kɔnt blɔd sɛl dɛn we dɛn de chɛk yu wɛlbɔdi ɔltɛm.

If yu Kɔmplit Blɔd Kɔnt (CBC) sho se yu gɛt smɔl rɛd blɔd sɛl, pletlɛt, ɔ nyutrofil, yu mɛdikal tim go du mɔ tɛst. Fɔ ɛgzampul, dɛn go chɛk yu blɔd fɔ si if di antibodi dɛn we gɛt fɔ du wit Evans Syndrome dɔn bɔku. Dɛn go chɛk bak fɔ ɔda tin dɛn we kin mek pɔsin gɛt saytopenia, lɛk sɔm infɛkshɔn ɔ kansa.

Dɔktɔ dɛn kin kɔnfirm Evans Syndrome bay we dɛn nɔ gri wit ɔl di ɔda tin dɛn we kin mek i gɛt dis sik. Sɔntɛnde, dɛn kin nid bak fɔ du CT skan (kɔmpyuta tomografi skan) ɔ bon mɛro bayɔpsi fɔ mek dɛn nɔ no ɔda tin dɛn we de apin.

Yu tink se kɔmplit mɛrɛsin de fɔ di sik we dɛn kɔl Evans Syndrome? Aw dɛn kin trit am?

Infakt, no kɔmplit mɛrɛsin nɔ de fɔ Evans Syndrome, ɔ ɛni ɔda sik we pɔsin kin gɛt we i de fɛt insɛf. Dɔktɔ dɛn kin trit dɛn ɔtoimyun sik ya bay we dɛn kin gi yu mɛrɛsin dɛn we kin mek yu imyun sistɛm nɔ wok fayn.

Apat frɔm dat, dɛn kin trit yu sik dɛn wan bay wan. Fɔ ɛgzampul, if yu blɔd sɛl nɔ bɔku, yu dɔktɔ go ebul fɔ kɔrɛkt dis bay we yu de gi yu blɔd wan wan tɛm .

Lɛk bɔrku sik dɛm wae kin kam wit pɔrsin wae de fɛt fɔ lɔng tɛm, Evans Syndrome kin bɛtɛ ɛn wɔs as tɛm de go. Sɔmtɛm i kin tan lɛk se di sayn dɛm kin go (dɛn kin kɔl am rɛmishɔn) , bɔt afta dat dɛn kin kam bak ɔr kin wɔs (dɛn kin kɔl am rilaps ).

Yu kin nid fɔ tray difrɛn tritmɛnt dɛn ɔlsay na yu layf, bikɔs dɛn kin chenj as tɛm de go. Yu dɔktɔ go tray fɔ protɛkt yu frɔm di siriɔs prɔblɛm dɛn we kin kam wit di sik we dɛn kɔl Evans Syndrome.

Wetin na di tritmɛnt dɛn?

Di standad tritmɛnt fɔ Evans Syndrome na fɔ tek mɛrɛsin we de mek pɔsin nɔ ebul fɔ fɛt di sik ɛn if nid de, fɔ gi pɔsin blɔd. Dɛn imyun suprɛsant ya de wok bay we dɛn de ridyus di mistek atak we yu imyun sistɛm de mek.

Men kayn mɛrɛsin dɛn we dɛn kin gi:

• Kɔtikosterɔyd dɛn lɛk prɛdnison . Bɔku tɛm, dis na di fɔs tritmɛnt we dɛn kin gi.
• Intravenous immunoglobulin therapy (IVIg) involv fכ gi sכlushכn we gεt hכman antibodi dεm tru wan vein. dis nyu antibodi dεm kin biεn di fכlt כtoimyun antibodi dεm εn disable dεm.

If yu nɔr de du wɛl to di standad tritmɛnt dɛm, yu dɔktɔ kin tray ɔda tritmɛnt dɛm. Dɛn tin ya na:

• Monoklonal antibodi dεm , lεk rituximab . Dis na antibodi dɛm we dɛn mek na lab. Sɔmtɛm dɛn tin ya kin stɔp di ɔtoimyun rεspכns. Yu dɔktɔ kin tɛl yu bɔt dɛn tin ya if ɔda mɛrɛsin dɛn nɔ de wok.
• Di we aw dɛn kin pul di bɔdi we dɛn kɔl splenectomy . If tin tranga, yu dɔktɔ kin tɛl yu fɔ du ɔpreshɔn fɔ pul yu splin. Yu splin na di say we dɛn kin pul ol blɔd sɛl dɛn. So we dɛn pul di splin, di prɔses kin slo smɔl.

Ɛni kɔmplikeshɔn ɔ sayd ɛfɛkt de fɔ di tritmɛnt?

We yu tek di imyun supεrεnt, di imyun sistεm in rεspכns to yu כtoimyun sik de rεdכks. Bɔt, yu imyuniti fɔ infɛkshɔn kin ridyus bak . So yu go nid fɔ tek spɛshal tin dɛn fɔ mek yu nɔ sik.

Yu dɔktɔ kin tɛl yu fɔ gi yu ɔda vaysin dɛn apat frɔm di wan dɛn we yu dɔn ɔlrɛdi gɛt. We yu imyun sistɛm wik (immunocompromised), yu kin gɛt sik dɛn we yu nɔ go gɛt nɔmal wan.

Fɔ liv wit Evans Syndrome kin afɛkt layf?

Evans Syndrome nɔr kin afɛkt yu layf. Sɔm pipul dɛn kin jɔs gɛt sɔm kayn sik wae nɔr kin pasmak, wan wan tɛm. Bɔt sɔm prɔblɛm dɛn lɛk blɔd, at sik, ɛn infekshɔn kin mek pɔsin in layf de pan denja.

If yu gɛt sɛkɔndari Evans syndrome, we min se yu gɛt am wit ɔda krɛse sik, dat kin afɛkt yu layf bak. Yu kin gɛt prɔblɛm dɛn we kin mek yu layf de pan denja we kin kam wit yu ɔda sik.

Wetin na de luk fɔ pɔrsin wae gɛt Evans Syndrome?

De ɛkspiriɛns wae pipul dɛm wae gɛt Evans Syndrome kin gɛt kin difrɛn bad bad wan. Di sayn dɛm kin bi smɔl ɔr kin tranga. Sɔm pipul kin fil lɛk se dɛn sik kin go ɔlsay (rɛmishɔn). Ɔda pipul dɛn kin gɛt dɛn bak leta (relaps).

Bɔku pipul dɛn nid sɔm kayn tritmɛnt ɛn dɛn nid fɔ chɛk dɛn ɔltɛm na dɔktɔ. Bɔku tɛm, di tritmɛnt dɛn kin wok fayn, bɔt nɔto ɔltɛm. Sɔntɛnde, i kin tan lɛk se di tritmɛnt dɛn we dɛn kin gɛt kin go dɔŋ as tɛm de go. Yu go nid fɔ tray ɔda tritmɛnt dɛn.

Aw a kin tek kia ɔf misɛf we a de liv wit Evans Syndrome?

If yu gɛt Evans Syndrome, i impɔtant fɔ kip kɔmpin wit yu dɔktɔ chɛk-ap ɔltɛm . Ivin if yu fil fayn, yu dɔktɔ go want fɔ wach yu sik ɛn kech am kwik if i wɔs.

Dɔn bak, yu fɔ pe atɛnshɔn to yusɛf ɔltɛm ɛn wach fɔ ɛni nyu sayn. If yu gɛt kol we nɔ de bɛtɛ, ɔ if yu gɛt blɔd we yu nɔ ebul fɔ kɔntrol, kɔl yu dɔktɔ wantɛm wantɛm .

Us kwɛstyɔn dɛn a fɔ aks mi dɔktɔ?

Yu kin aks yu dɔktɔ kwɛstyɔn dɛn lɛk dɛn wan ya:

• Us kayn blɔd sɛl dɛn a nɔ gɛt?
• Aw bɔku dɛn dɔn go dɔŋ?
• Us simptom ɔ wɔnin sayn dɛn a fɔ luk fɔ?
• Aw a go no if di tritmɛnt de wok ɔ nɔ de wok?
• Wetin kin apin if di tritmɛnt nɔr woke?
• Ustɛm a fɔ buk mi nɛks dɔktɔ apɔntinmɛnt?

Evans Syndrome na wan sik wae nɔr kin bɔrku wae yu nɔr dɔn yɛri bɔt bifo. De sayn dɛm kin strenj ɛn de mɔna yu. Fɔ ɔndastand wetin de apin ɛn wetin i min kin bi smɔl prɔblɛm.

Pan ɔl we Evans Syndrome na sik we pɔsin kin gɛt fɔ ɔl in layf, nɔto di sem tin ɔltɛm. Kip di op se yu go fil fayn, at least sɔntɛnde. I nɔ mata aw yu fil, yu mɛdikal tim go de fɔ gi yu di kia we yu nid.

Faynal Mɛsej fɔ Tek-Hom

Okay, so lɛ wi mɛmba yu bɔt sɔm pan di impɔtant tin dɛn we wi dɔn tɔk bɔt.

• Wetin na di sik we dɛn kɔl Evans Syndrome?Na sik we nɔ kin apin so ɔltɛm we yu yon imyun sistɛm kin atak yu yon blɔd sɛl.
• Dis kin mek di rɛd blɔd sɛl dɛn ( anemia ), di pletlɛt dɛn (thrombocytopenia), ɛn sɔntɛm di nyutrofil dɛn (nyutropenia) go dɔŋ.
• Sɔm kayn sayn dɛm lɛk fɔ taya pasmak, fɔ gɛt blɛsin, fɔ brus izi, fɔ blɔd bɔku tɛm, ɛn fɔ gɛt infɛkshɔn ɔltɛm .
• Pan ɔl we no kɔmplit mɛrɛsin nɔ de fɔ dis, dɛn kin kɔntrol di sik dɛn wit tritmɛnt .
• I rili impɔtant fɔ fala di dɔktɔ dɛn advays ɔltɛm ɛn pe atɛnshɔn to di sayn dɛn we de sho se yu gɛt dis sik.
• Nɔto yu wan de. Yu dɔktɔ dɛn ɛn di wan dɛn we yu lɛk go ɛp yu. I rili impɔtant bak fɔ de tink gud wan.

A op se dis infɔmeshɔn go ɛp yu. If yu gɛt ɛni kwɛstyɔn, nɔ shem fɔ tɔk to yu dɔktɔ.

Evans sindrom, ɔtoimyun sik, saytopenia, anemia, trombosaytopenia, nyutropenia, blɔd dizayd