Yu kin taya ɔltɛm? Lɛ wi lan ɔltin bɔt folate deficiency anemia!

Yu kin fil bak se yu taya ɔl di de, yu nɔ ebul fɔ du ɛnitin? Ɔ sɔntɛnde yu kin fil lɛk se yu bɔdi de kol ɛn i kin at fɔ blo smɔl? Dis nɔto jɔs random tin, sɔntɛm yu bɔdi nɔ gɛt di nyutrient folate, we kin de mek yu nɔ gɛt blɔd, dat na, anemia. Tide, lɛ wi tɔk bɔt wetin na folate deficiency anemia, wetin mek i kin apin, ɛn aw fɔ avɔyd am.

Wetin na Folate Deficiency Anemia we pɔsin kin gɛt? Lɛ wi ɔndastand am simpul wan!

Fɔ tɔk am simpul wan, fɔlɛt dɛfisiɛns anemia na blɔd disɔda we kin kam bikɔs yu nɔ gɛt fɔlet ɔ vaytamɛn B9 na yu bɔdi. Wetin kin apin pan dis na dat di nɔmba fɔ di rɛd blɔd sɛl dɛn na yu bɔdi kin smɔl pas aw i kin bi ɛn di rɛd blɔd sɛl dɛn we de de nɔ kin bɔku. Tink bɔt dis, dɛn rɛd blɔd sɛl ya kin kɛr ɔksijɛn go ɔlsay na wi bɔdi. So we dɛn sɛl ya de dɔŋ, big, ɔ nɔ ebul fɔ wok fayn, di ɔksijɛn we di bɔdi de gɛt de go dɔŋ. As tɛm de go, dis ɔksijɛn we nɔ gɛt na in de mek yu taya, wik, ɛn kol.

Wetin mek anemia kin apin we folate nɔ de? Wetin kin apin insay di bɔdi?

Yu no aw wi rɛd blɔd sɛl dɛn kin mek? fכs dεn kin fכm frכm stεm sεl dεm na di bon mכro insay wi bon dεm. Dɛn rɛd blɔd sɛl ya kin gro smɔl smɔl ɛn jɔyn wi blɔd, ɛn dɛn kin kɛr ɔksijɛn go na ɔl di ɔgan ɛn tisu dɛn na di bɔdi.

Na ya, wan tin we dɛn kɔl folate impɔtant fɔ mek di rɛd blɔd sɛl dɛn we gɛt wɛlbɔdi, fayn fayn wan. I tan lɛk se yu de bil os wit simen. So, if yu bɔdi nɔ gɛt inof folate, yu bon mɛro nɔ go mek nɔmal rɛd blɔd sɛl dɛn. bifo dat, i de prodyuz wan abnכmal big tכp rεd bכdi sεl we dεn kכl ``megaloblasts.''

biכs dεn ``megaloblastic'' sεl dεm ya so big, sכm pan dεm nכ de ivin kכmכt na di bon mכro εn jכyn di bכdi. di sεl dεm we de du jכyn nכ de liv lכng lεk di hεlty rεd bכdi sεl dεm. Dɛn kin day kwik kwik wan. Na dat mek di nɔmba fɔ di rɛd blɔd sɛl dɛn na di bɔdi kin go dɔŋ, ɛn dis kin mek pɔsin gɛt anemia, we min se blɔd nɔ de. Yu ɔndastand?

Ɔda kayn wae dɛn de wae de mek pɔrsin nɔr gɛt bɛtɛ blɔd?

Yɛs, anemia na wan sik we bɔku pipul dɛn kin gɛt. Na bikɔs i nɔ gɛt wɛlbɔdi rɛd blɔd sɛl dɛn. Bɔku tin dɛn de we kin mek pɔsin nɔ gɛt bɛtɛ blɔd:

• big big rεd bכdi sεl dεm we nכ nכmal (dis na bak fכ di fכlet dεfichεns we wi de tכk bכt).
• Di prodakshɔn fɔ wɛlbɔdi rɛd blɔd sɛl dɛn nɔ de bɔku.
• Di liva ɛn splin de pwɛl di rɛd blɔd sɛl dɛn pasmak.
• Di lɛvɛl we di ɛmoglobin de go dɔŋ, we na wan prɔtin we de insay di rɛd blɔd sɛl dɛn we de kɛr ɔksijɛn.
• Ɛmoglobin nɔ de wok fayn, we min se i nɔ ebul fɔ kech ɔksijɛn fayn fayn wan.
• Di bɔs we di rɛd blɔd sɛl dɛn de bɔn na di blɔd.

di grup fכ anemia we di rεd bכdi sεl dεm we nכ nכmal de kכz dεn kכl am ``makrosaytik anemia``. wan kayn dis na ``megaloblastic anemia``. di wan dεm we de kam biεn de fכl כnda dis ``megaloblastic anemia``:

• Folate deficiency anemia we de mek pɔsin nɔ gɛt bɛtɛ blɔd
• Vitamin B12 dɛfisiɛns anemia
• Anemia we kin pwɛl pɔsin in bɔdi

Apat frɔm dis, ɔda kayn anemia we bɔku pipul dɛn dɔn yɛri bɔt na:

• Anemia we nɔ gɛt ayɔn
• Siklɔs sɛl anemia

Aw kɔmɔn tin kin apin we pɔsin nɔ gɛt bɛtɛ folate?

Fɔlayt nɔ kin bɔku so na di divɛlɔp kɔntri dɛn. Dis na bikɔs dɛn kin ad folet to bɔku it dɛn na dɛn kɔntri dɛn de. fכ egzampl, na Amɛrika, i dɔn bi mandatory fכ ad folate to it dεm frכm 1998. di rizin fכ dis na biכs fכlet rili implεnt fכ di divεlכpmεnt fכ di pikin we di pikin de fכm.

Dɔktɔ dɛn dɔn si se if pɔsin nɔ gɛt folate, i kin mek i bɔn sɔm prɔblɛm dɛn, mɔ di nyural tyub we nɔ fayn lɛk spina bifida. Na dat mek na bɔku kɔntri dɛn, dɛn kin ad folet to bɔku pan di it dɛn we wi kin it, mɔ di sid ɛn rays.

Udat de pan ay risk fɔ gɛt folate deficiency anemia?

Pipul dɛn de wae kin gɛt dis sik. Si if yu de insay dis kategori:

• Uman dɛn we dɔn rich di ej fɔ bɔn pikin: Di nid fɔ folet kin bɔku mɔ fɔ uman dɛn we de plan fɔ gɛt bɛlɛ, we dɛn gɛt bɛlɛ, ɛn we dɛn de gi dɛn bɛlɛ.
• Pipul dɛn we de drink pasmak: Rɔk de mek di bɔdi nɔ ebul fɔ tek di tin dɛn we de insay di bɔdi.
• Pipul dɛn we dɔn pas 60 ia.
• Pipul dɛn we gɛt prɔblɛm wit mɔni biznɛs: Na bikɔs i nɔ kin izi fɔ mek dɛn it tin dɛn we gɛt balans.
• Mama dɛn we gɛt bɛlɛ ɛn we de gi pikin milk.

Wetin kin mek pɔsin nɔ gɛt bɛtɛ folate?

Di men rizin na bikɔs wi nɔ kin gɛt inof folate frɔm di it dɛn we wi de it. Apat frɔm dat, ɔda rizin dɛn de we kin mek di bɔdi nɔ ebul fɔ tek ɔ yuz folate fayn fayn wan:

• Adikshɔn pan rɔm (`Alcohol use disorder`).
• Fɔ du dayalaysis tritmɛnt bikɔs ɔf di kidni we nɔ de wok fayn.
• Digεstiv sistεm sik dεm, fכ egzampl, Crohn in sik εn celiac sik.
• Yuz sɔm mɛrɛsin fɔ lɔng tɛm (e.g., fɔ ɛpilepshi, rεumatik dizayd, sɔm antibayɔtik, ɛn imyunosuprɛshɔn).
• di kכndishכn dεm we dεn kin gεt we dεn kin gεt frכm di pikin lεk ``Hereditary folate malabsorption`` (we di bכdi in ebul fכ abzכp fכlet de rεdכks frכm we dεn bכn am).

Wetin na di sayn dɛm fɔ dis? Aw yu no am?

Sɔntɛnde, folate deficiency anemia kin de witout ɛni simptom. Yu dɔktɔ kin jɔs fɛn am we yu du yu blɔd tɛst fɔ ɔda tin.

Bɔt we di sayn dɛn we de sho se yu gɛt dis sik, dɛn kin gɛt:

• Fɔ fil taya ɔltɛm (`fatigue`): I tan lɛk se di taya nɔ de go ivin afta yu dɔn slip.
• Fɔ fil se yu nɔ gɛt bɛtɛ trɛnk ɛn yu wik we yu de du tin dɛn we yu de du ɛvride.
• Diziz, fil lɛk se yu nɔ gɛt bɛtɛ ed.
• Pale skin (`pallor`): di say dεm lεk di fes, di lip dεm, εn di palm dεm de sho pale.
• Fɔ fil lɛk se yu at de bit fast, fɔ yɛri sawnd we de bit na yu chɛst, ɔ fil lɛk se yu at de skip bit (at de bit).
• I nɔ kin izi fɔ blo (dyspnea): I kin shɔt fɔ blo ivin wit smɔl smɔl wok dɛn.

Aw dɛn kin no dis sik kɔrɛkt wan ?

If yu gɛt dɛn sik ya, yu fɔ rili go to dɔktɔ. Yu dɔktɔ go du yu bɔdi ɛgzam ɛn aks bɔt yu mɛdikal histri ɛn di sayn dɛm. Bikɔs di sayn dɛm fɔ folate deficiency anemia tan lɛk bɔku ɔda sik dɛm, yu kin nid fɔ du bɔku blɔd tɛst fɔ no if na so i bi.

Di men wan dɛn fɔ dɛn blɔd tɛst ya na:

• Kɔmplit blɔd kɔnt (CBC): Dis kin chɛk bɔku tin dɛn lɛk di nɔmba fɔ di rɛd blɔd sɛl dɛn, di wayt blɔd sɛl dɛn, ɛn di pletlɛt dɛn we de na yu blɔd, ɛn ɔmɔs ɛmoglobin de.
• Peripheral blood smear (PBS): Dis min se yu fɔ tek wan sɛmpul pan yu blɔd ɛn luk am ɔnda maykroskɔp. Dis kin mek yu si ustɛm di blɔd sɛl dɛn shep, if dɛn big ɔ smɔl, ɛn if ɛnitin de we nɔ fayn.
• rεtikulכsayt kכnt: rεtikulכsayt dεm na yכŋ, immature rεd bכdi sεl dεm. Dis tɛst de chɛk if yu bon mɛro de mek inof rɛd blɔd sɛl.

Apat frɔm dɛn tɛst ya, yu dɔktɔ go chɛk yu blɔd folate lɛvɛl bak. dis kin mכsu insay yunit dεm we dεn kכl `nanograms per mililita` (`ng/mL`).

• Deficient: Les dan 2 nanogram pan wan mililita (`< 2 ng/mL`).
• Bכdalayn: Bitwin 2 εn 4 nanogram pan wan mililita (`2 ng/mL - 4 ng/mL`).
• Sufayf: I pas 4 nanogram pan wan mililita (`> 4 ng/mL`).

Bikɔs bɔku tɛm we yu nɔ gɛt vaytamɛn B12 ɛn we yu nɔ gɛt fɔlet kin apin togɛda, di dɔktɔ go chɛk yu vaytamɛn B12 lɛvɛl bak.

Wetin na di tritmɛnt dɛm fɔ dis?

Di gud nyus na dat, tritmɛnt de fɔ dis, ɛn i kin rili fayn.

Di men tritmɛnt na fɔ gi vaytamɛn B9 sɔpɔtmɛnt.Dɛn kin gi dɛn tin ya as pils fɔ tek bay mɔt. Fɔ sɔm pipul dɛn we nɔ kin izi fɔ swɛla pils, dɛn kin gi dɛn bak as injɛkshɔn, ɔ dɛn kin put dɛn na dɛn bɛlɛ (IV) wit salin. Dɛn sɔpɔt ya kin nid fɔ tek ɔltɛm fɔ sɔm mɔnt.

Yu dɔktɔ kin tɛl yu bak se yu fɔ chenj di tin dɛn we yu de it. If na wan ɔndalayn mɛrɛsin sik de mek pɔsin nɔ gɛt folate, i impɔtant fɔ trit da sik de bak.

Yu tink se dɛn kin mek dɛn nɔ gɛt di sik we dɛn kɔl folate deficiency anemia?

Yɛs, i rili pɔsibul. I izi fɔ avɔyd dis kayn tin if yu tek kia ɔf dɛn tin ya:

• Gɛt yu ɛvride doz fɔ folate, ɔ tru di it dɛn we yu de it ɔ bay we yu tek sɔpɔt we gɛt vaytamɛn B9 (fɔlik asid).
• Ridyus di rɔm we yu de drink, ɔ stɔp fɔ drink ɔltogɛda. If pɔsin drink pasmak, dat kin mek di bɔdi nɔ ebul fɔ tek di tin dɛn we impɔtant pas ɔl, lɛk fɔlet.
• If yu gɛt ɛni sik we de mek yu bɔdi nɔ ebul fɔ tek ɔ yuz folate, tɔk to yu dɔktɔ bɔt am.

Aw bɔku folate (vitamin B9) wi nid fɔ wan de?

di vaytam in B9 we wi kin gεt nכmal wan frכm it dεn kכl am folate. di vaytam in B9 we dεn ad pan it כ we de insay vaytam in pil dεm dεn kכl am fכlik asid. Di amount of folate we wi nid fɔ wan de dipen pan sɔm tin dɛn:

• Ej: As yu de ol, yu nid fɔ gɛt folate mɔ ɛn mɔ.
• di say we wi de it: Wi bכdi de tek fכlik asid bεtεh pas fכlet we de kכmכt frכm it.

di rεkomεndεd Deli Alawεns (RDA) dεn de εksprεs insay maykrogram (mcg), we dεn mεzj insay Dayεt fכlet Ikwivalεnt (DFE). Dis kin tan lɛk se i kin kɔnfyus smɔl, bɔt i simpul.

• `1 mcg` fכlet frכm it ikwal to `1 mcg DFE`.
• if yu gεt fכlik asid we dεn ad pan it כ frכm vaytam in pil dεm we yu tek wit it, 1 mcg fכlik asid ikwal to 1.67 mcg DFE (we min se di bכdi de abzכp mכr).
• 1 mcg fכlik asid frכm vaytam in pil dεm we dεn tek pan εmpti bεlε ikwal to 2 mcg DFE (we di bכdi de abzכp ivin bεtε).

fכ egzampl, if yu tek mכltivitamin wit `200 mcg` fכlik asid pan εmpti bεlε, dεn kin kכl am as `400 mcg DFE` (200 mcg x 2 = 400 mcg).

Wan avrej big pɔsin nid 400 mcg DFE fɔ wan de. uman dεm we bεlε nid 600 mcg DFE, εn mama dεm we de gi bεlε nid 500 mcg DFE. I bɛtɛ fɔ aks yu dɔktɔ fɔ di rayt mɔni fɔ yu.

Us it dɛn we gɛt bɔku folate?

Bɔt gud tin na dat, bɔku it dɛn de we fayn fɔ mek pɔsin gɛt folate. Tray fɔ ad dɛn tin ya to yu it:

• Mit: Bif liva (bɔku dis de, bɔt yu fɔ tink bak bɔt kɔlɔstrel) .
• Grin vegjetabul ɛn ɔyl: Grin lɛk spinach, kelɛ, kɔla grɛn, asparagus, Brussels sprouts, avokado, brɔkoli.
• Fɔtifyed it dɛn: Sɔm siriɔs (brɛkfas siriɔs), rays, bred, pasta, bred flawa, kɔnmil. (Chɛk di lɛbl fɔ si if dɛn ad fɔlik asid.)
• Bins: Kidni bins, kidni bins.
• Nat: Pinat, walnut.
• Frut: Sitrus frut lɛk ɔrɛnj ɛn tanjɛrin ɛn dɛn jus.

Mɛmba se: Fɔlet kin pwɛl we dɛn kuk dɛn it ya fɔ lɔng tɛm, lɛk we dɛn bɔyl am na wata. So kuk dɛn smɔl as yu ebul, ɔ ad dɛn to yu it if yu kin it dɛn raw (wash dɛn fayn fayn wan).

Yu tink se dis sik go wɛl if dɛn trit am?

I go mɔs bi se na yɛs! Di tritmɛnt fɔ folate deficiency anemia kin rili fayn. Insay sɔm mɔnt we dɛn bigin fɔ tek vaytamɛn B9, bɔku pipul dɛn kin bigin fɔ mek wɛlbɔdi rɛd blɔd sɛl dɛn bak, ɛn dɛn kin gɛt bɛtɛ sik dɛn smɔl smɔl.

Ustɛm yu fɔ tɔk to dɔktɔ bɔt folate deficiency anemia?

Mek shɔ se yu go to dɔktɔ fɔ advays pan kes dɛn lɛk dɛn wan ya:

• If yu nɔ shɔ ɔmɔs folate yu nid fɔ wan de, ɔ if yu de gɛt inof pan am.
• If yu gɛt sayn dɛm fɔ anemia (lɛk wae yu taya, yu wik, yu nɔr de blo fayn).
• If yu gɛt ɔda sik we kin mek yu nɔ gɛt folate.
• If yu bin dɔn gɛt tritmɛnt fɔ folate deficiency anemia ɛn fil lɛk se yu sik dɛn de kam bak.
• If yu de plan fɔ gɛt bɛlɛ, ɔ yu dɔn gɛt bɛlɛ. Dis rili impɔtant!

I kin mek yu at pwɛl smɔl fɔ no se yu gɛt prɔblɛm wit yu blɔd sɛl dɛn. Bɔt mɛmba se, sayn na di we aw yu bɔdi de tɛl yu se sɔntin nɔ fayn. I kin bi se yu nid fɔ it fayn fayn it, ɔ i kin bi wan sik we de mek yu gɛt di sik. Yu dɔktɔ go wok wit yu fɔ fɛn di tin we de mek yu gɛt dis sik. Dɛn go gi yu bak vaytamɛn B9 sɔpɔtmɛnt ɛn ɔda tritmɛnt dɛn if nid de. If yu trit yu fayn ɛn fala wetin yu dɔktɔ tɛl yu, i go mɔs bi se yu sik go bɛtɛ.

Di tin dɛn we impɔtant pas ɔl fɔ mɛmba (Take-Home Message) .

Okay, so na sɔm tin dɛn we wi fɔ mɛmba frɔm wetin wi dɔn tɔk bɔt:

• fכlet (vitamin B9) na imכtant nyutriεnt fכ mek hεlty rεd bכdi sεl dεm.
• if yu nכ gεt folate i kin mek big, abnכmal rεd bכdi sεl dεm (`megaloblasts`) fכm, we kin mek i gεt anemia.
• If yu gɛt sɔm sayn dɛn lɛk fɔ taya ɔltɛm, wik, yu skin kin shayn, ɛn yu nɔ kin ebul fɔ blo, go to dɔktɔ.
• Put tin dɛn we gɛt bɔku folate (lɛgim, grɛn vɛjitebul, nɛt, it dɛn we dɛn ad folate) insay yu it.
• Di wan dɛn we gɛt bɛlɛ, we de gi pikin dɛn bɛlɛ, ɛn uman dɛn we de tray fɔ gɛt bɛlɛ fɔ tek tɛm mɔ wit folate. Tek fɔlik asid pils lɛk aw yu dɔktɔ tɛl yu.
• Bɔrku tɛm dis sik kin wɛl ɔltogɛda wit tritmɛnt.

So, tek kia ɔf yu bɔdi. It di it we balans. If yu gɛt ɛni prɔblɛm, nɔ fred fɔ tɔk to dɔktɔ. Fɔ gɛt wɛlbɔdi na di tin we impɔtant pas ɔl!

` Folate, anemia, vaytam in B9, bכdi we de dכn, rεd bכdi sεl dεm, nyutrishכn we de dכn, bεlε hεlth