Wetin na Gastrin? I kin afɛkt yu bɛlɛ prɔblɛm?

Yu dɔn ɛva wɔnda ɔmɔs tin kin apin insay wi bɔdi, mɔ we wi dɔn it? Wi gɛt wan grup we gɛt smɔl smɔl kemikal mɛsenja dɛn na wi bɔdi we de ɛp ɔl dis fɔ apin. Wi kin kɔl dɛn ɔmon dɛn ya. Tide wi go tɔk bɔt wan pan dɛn kayn spɛshal ɔmon dɛn de. Dat na gastrin. dis gastrin rili imכtant fכ di wok we wi dijestiv sistεm de wok.

Wetin Gastrin rili de du?

Okay, naw mek wi si wetin dis padi we dem kol Gastrin de du fo wi bodi. I gɛt bɔku men wok dɛn.

• di asid we yu de mek na yu bɛlɛ: di tin we impɔtant pas ɔl na fɔ tɛl yu bɛlɛ fɔ pul di gastric asid. Dis gastric acid na wetin wi kɔl haydroklɔrik asid. If dis nɔ de, i kin rili at fɔ dayjɛst it.
• di bεlε mכsul dεm de wok: Gastrin de εp bak di mכsul dεm na yu bεlε fכ wok fayn fayn wan, we min se i de mek di gεstrik mכtiliti, we de εp fכ miks εn brok dכn it.
• Rinyu di Bɛlɛ Wɔl: Di dilik layn we de na wi bɛlɛ, we na di myukɔsa, nid fɔ de nyu ɔltɛm. Gastrin de ɛp wit dis bak.
• Fɔ mek di gal blad ɛn pankrias wok: Gastrin, wit ɔda ɔmon we dɛn kɔl cholecystokinin, de ɛp yu gal blad ɛn pankrias fɔ kɔntrakt ɛn pul di jus dɛn we de mek yu digest.

Wetin na di difrɛns bitwin Gastrin ɛn Gastric acid?

Yu tink se dis kin mek yu kɔnfyus smɔl? Fɔ tɔk am simpul wan, i tan lɛk dis. Gastrin na wan ɔmon . I tan lɛk lɛta. Dis lɛta tɛl di bɛlɛ se, "Okay, naw rilis gastric acid." afta dat dis gεstrik asid de mek di dijestiv εnzym pεpsin wok. tכgeda, dεn tu de mek di gastric jus na wi bεlε. Yu ɔndastand?

Usay dɛn kin mek gastrin?

di כgan dεm we de na wi dijestiv sistεm de mek di gastrin fכs. dis כmon de kכmכt frכm wan spεshal kayn sεl we dεn kכl G-sεl dεm. Di lɛta "G" tinap fɔ "gastrin."

Bɔku pan di gastrin kin kɔmɔt na yu bɛlɛ , mɔ di ɔda pat we de dɔŋ na yu bɛlɛ (wi kin kɔl am di antrum). dis G-sεl dεm de na di gland dεm we de na di wכl na yu bεlε. apat frכm dat, sכm gastrin de kכmכt frכm di duodenum, we na di fכs pat pan yu sכm sכm intestכn, εn di pankrias.

Us tin dɛn kin afɛkt di we aw di gastrin kin kɔmɔt?

I wɔndaful aw gastrin kin kɔmɔt we yu tink bɔt fɔ it! Aw yu no dat? wi bren εn di dijestiv sistεm de kכnekt כltεm tru wan spεshal nεtwכk fכ nεv dεm we dεn kכl di vagal nεv dεm. Infɔmeshɔn kin travul go ɛn kam tru dɛn nɛv dɛn ya.

so, we yu tink bכt it, di vagal nεv dεm na yu bren de sεnd mεsej to di bεlε, se, "Okay, it de kam, rilis gastrin εn rεdi fכ digεst." Dɔn we yu bigin fɔ it, di nɛf dɛn we de na yu bɛlɛ kin no se it dɔn go insay ɛn dɛn kin pul mɔ gastrin.

Ɔda tin dɛn we de mek di gastrin kɔmɔt:

• di inkrεs pan di pH na di bεlε (dat na we di asid de dכn).
• Dɛn kin pul di bɛlɛ wɔl dɛn we it de kam insay.
• Sɔm it dɛn , mɔ di wan dɛn we gɛt prɔtin, kin go insay di bɛlɛ.

Gastrin de mek di gastric acid kɔmɔt, we de mek di pepsin wok. tכgeda, dεn de brok dכn εn digεst di protin dεm na di bεlε. Gastrin de mek di mכsul dεm na di bεlε muv bak.

Aw yu kin stɔp di rilis fɔ gastrin?

as di it de ɛmti frכm yu bεlε εn de muv insay di fכs pat pan di sכmכl intestinal, di duodenum, di nεks stej fכ digεst de bigin. na da tεm de di rilis fכ gastrin bigin fכ dכn. as di it de kכmכt na di bεlε εn di bεlε asid lεvεl de inkrεs, di gastrin de dכn.

we it go insay di duodenum, yu gal blad εn pankrias de rilis dεn dijestiv jus dεm. Dɔn, wi dijestiv sistɛm de pul ɔda ɔmon we dɛn kɔl somatostatin. dis somatostatin de tכn כf כda כmon dεm (lεk gastrin). I tan lɛk se yu dɔn ɔf wan swich.

Aw fɔ chɛk di lɛvɛl we di gastrin de?

Speshal blɔd tɛst de fɔ chɛk yu gastrin lɛvɛl. Wi kin kɔl am di gastrin tɛst. Wan pɔsin we de kia fɔ wɛlbɔdi biznɛs, lɛk dɔktɔ ɔ nɔs, kin tek smɔl blɔd frɔm wan vein na yu an ɛn sɛn am na lɛb fɔ mek dɛn tɛst am.

Wetin mek mi gastrin lɛvɛl impɔtant?

Dɔktɔ dɛn kin chɛk yu gastrin lɛvɛl fɔ si if i tu ay . di lכw gastrin lεvεl nכ kin bכku, bכt di hכy gastrin lεvεl kin sho sכm gεstrointestinal sik dεm εn kכndishכn dεm.

Wetin di εlevεt gastrin lεvεl (Hypergastrinemia) min?

We di gastrin lɛvɛl go ɔp, wi kin kɔl am haypagastrinemia. Sɔntɛnde, haypa gastrinemia kin min se yu gɛt tumbu dɛn we de mek gastrin na yu bɔdi, we dɛn kɔl gastrinomas. Dɛn tin ya kin apin na yu pankrias ɔ duodenum.

Ɔda tɛm, haypa gastrinemia kin min se sɔntin de na yu bɛlɛ we de mek i nɔ mek gastric acid. we di asid na di bכdi dכn, mכr gastrin de kכmכt. כlso, di signal dεm we nכmal fכ stכp di gastrin prodakshכn de disrupt.

Wetin kin apin if di gastrin lɛvɛl go ɔp?

if yu gastrin lεvεl hכy, di כmכnt כf gεstrik asid na yu bεlε εn duodenum kin bi tu hכy. Tumɔs asid kin pwɛl di dilik layn we de protɛkt yu bɛlɛ ɛn yu duodenum, ɛn dis kin mek yu gɛt ɔlsa, we dɛn kin kɔl bak peptik ɔlsa sik.

Dɔn bak, if yu gɛt bɔku asid na yu bɛlɛ, i kin mek yu gɛt wan sik we dɛn kɔl GERD (Gastroesophageal Reflux Disease), we na wan sik we kin te we asid kin kam ɔp na di trot. If yu gɛt peptik ɔlsa sik ɔ GERD ɛn i nɔr de bɛtɛ wit mɛrɛsin, yu dɔktɔ kin chɛk yu gastrin lɛvɛl.

Us mɛrɛsin kin gɛt fɔ du wit di ay gastrin lɛvɛl?

If yu gɛt gastrinomas, yu gastrin ɛn gastric acid lɛvɛl kin go ɔp. Gastrinomas na wan kayn pankrεas nyuroεndokrin tכmכro (PET) we de kכl gastrin. Dɛn kin gɛt kansa ɔr nɔr kin gɛt kansa.

Di tin dɛn we kin mek pɔsin gɛt gastrinomas:

• Zollinger-Ellison sindrom we gɛt di sik.
• Mכltipכl εndokrin niכplasia tayp 1 (MEN1).

di kכndishכn dεm we di gastrin εn gεstrik asid de εlevεt witout gastrinomas:

• Kidni we nɔ de wok fayn fɔ lɔng tɛm.
• Gastrik ɔlt ɔbstrɔkshɔn (GOO).

If yu gastric acid prodakshɔn nɔ bɔku, yu kin gɛt ay gastrin lɛvɛl bɔt yu gɛt smɔl gastric acid lɛvɛl. dis kin bi bikoz fכ atrofik gastritis, we na wan kכndyushכn we di sεl dεm we de prodyuz bכdi asid de pwεl.

Di men tin dɛn we kin mek pɔsin gɛt atrofik gastritis:

• H. pylori infεkshכn.
• כtoimyun sik dεm (e.g. כtoimyun atrofik gεstritis).

Ɔda tin dɛn we kin mek di gastric acid prodakshɔn nɔ bɔku:

• mεdikeshכn dεm we de blכk asid, lεk H2 blכk כ protכn pכmp inhibito (PPI).
• Vagotomy (fɔ pul ɔ kɔt di vagal nɛv bay ɔpreshɔn).

Wetin a fɔ du if a gɛt sayn dɛn we de sho se a gɛt bɔku gastrin?

If yu gɛt bɛlɛ simptom, mɔ if i kin apin ɔltɛm ɔr dɔn de de fɔ lɔng tɛm, i impɔtant fɔ go to dɔktɔ. Na sɔm sayn dɛm wae kin gɛt fɔ du wit wae yu gɛt bɔrku gastrin:

• Bɛlɛ de pen ɔ kramp.
• Chest pen we de kɔntinyu ɛn nɔ de it fayn.
• Asid riflɔks ɔ it we de stɔp na di trot.
• Trot we de at ɔltɛm ɛn we de ala lawd lawd wan.
• Dayarɛa we de kɔntinyu fɔ de.
• Prɔblɛm dɛn we gɛt fɔ du wit di we aw pɔsin de digest.

Dɛn sayn ya kin sho se yu gɛt bɔku bɔku gastric acid, ɔ yu gɛt atrophic gastritis, peptic ulcer disease, ɔ GERD. Dis kin gɛt fɔ du wit gastrin ɔ nɔ kin gɛt fɔ du wit am. Bɔt i impɔtant fɔ no ɛn trit dɛn sik ya kɔrɛkt wan.

Mɛmba se, if yu gɛt sɔm kayn sik lɛk dis, nɔr tray fɔ no yusɛf bay wae yu de luk fɔ infɔmeshɔn na di intanɛt. I bɛtɛ fɔ go to dɔktɔ ɛn gɛt advays.

Mɛsej we dɛn kin kɛr go na os

Okay, so lɛ wi luk sɔm simpul tin dɛn fɔ mɛmba bɔt di gastrin we wi bin tɔk bɔt.

• Gastrin na impɔtant ɔmon we de na wi dijestiv sistɛm .
• di men wok we i de du na fכ tεl di bεlε fכ rilis di gεstrik asid .
• If yu bɛlɛ asid tu ay ɔ tu smɔl , i kin gɛt fɔ du wit gastrin.
• If yu gɛt ɛni bɛlɛ simptom, ɔr kɔndishɔn wae nɔr de bɛtɛ wit tritmɛnt, dɔktɔ kin tɛst yu gastrin lɛvɛl.
• Sɔntɛnde, if yu gɛt bɔku gastrin, dat kin bi sayn fɔ se yu gɛt mɛrɛsin, so i impɔtant fɔ go to dɔktɔ if yu gɛt sɔm sayn dɛn.

So, Gastrin na smɔl bɔt pawaful tin we de wok kwayɛt wan na wi bɔdi. Fɔ no dis go rili impɔtant fɔ yu wɛlbɔdi. If yu gɛt ɛni ɔda kwɛstyɔn, nɔ shek fɔ aks yu dɔktɔ.

` Gastrin, ɔmon, dijeshɔn, bɛlɛ asid, peptik ɔlsa, GERD, haypagastrinemia