Aw liva prɔblɛm kin afɛkt di kidni dɛm dairekt wan: Lɛ wi lan gud gud wan bɔt Epatorenal Syndrome!

Yu dɔn ɛva tink se siriɔs prɔblɛm wit yu liva kin mek yu tu kidni dɛn we gɛt pafɛkt wɛlbɔdi nɔ wok wan tɛm? Na tin we de mek pɔsin fred, nɔto so? Tide wi go tɔk bɔt wan siriɔs, layf de pan denja we kin apin wit di liva we nɔ de wok fayn. Dis na wetin dɔktɔ dɛn kin kɔl Hepatorenal Syndrome (HRS) . Lɛ wi tek tɛm luk wetin i bi, wetin mek i kin apin, ɛn wetin ɔda tin wi kin du.

Wetin na di Epatorenal Syndrome?

Fɔ tɔk am simpul wan, ɛpatorenal syndrome (HRS) na wan sik we yu liva nɔ de wok fayn, na wan rili siriɔs kɔmplikeshɔn we kin apin na di las stej dɛm we yu liva nɔ de wok fayn. Wetin kin apin pan dis kes na dat yu kidni dɛn kin lɔs dɛn wok wantɛm wantɛm bikɔs ɔf prɔblɛm wit di liva. Wetin spɛshal na dat dɛn kin tek dis as prɛrenal akyu kidni fayl . Dis min se yu kin gɛt dis sik ivin if yu nɔr gɛt ɛni sik na yu kidni bifo ɛn nɔr chenj na yu bɔdi ɔr pwɛl yu kidni. Yu kidni kin gɛt wɛl bɔdi fayn fayn wan, bɔt bikɔs ɔf di liva prɔblɛm, di blɔd we de gi dɛn kin ambɔg, ɛn dɛn nɔ kin ebul fɔ du dɛn wok.

Tink bɔt am lɛk wata pɔmp we de wok fayn, bɔt if di wata paip we de go na di wata tank blok, di wata nɔ go kɔmɔt. Di kidni dɛn fayn, bɔt prɔblɛm wit di liva kin mek di blɔd vesel dɛn we de kɛr blɔd go na di kidni dɛn kin blok ɛn smɔl. Dɔn, di kidni dɛn nɔ kin gɛt di blɔd we dɛn nid, ɛn smɔl smɔl dɛn kin stɔp fɔ wok. Dɛn kin tek dis as imejensi , ɛn bɔku tɛm, di wangren tritmɛnt fɔ dis fɔ ɔltɛm na fɔ transplant liva .

Udat dɛn dis kayn tin kin afɛkt mɔ?

Dis sik we dɛn kɔl hepatorenal syndrome (HRS), kin mɔna pipul dɛn we gɛt siriɔs liva sik . Mɔtalman, pipul dɛm wae gɛt dis sik wae nɔr de mɛn , wae dɛn liva dɔn wik smɔl smɔl as tɛm de go, na dɛn kin gɛt dis sik pasmak. Yu no se bikɔs ɔf dis kayn sik we kin de na di liva fɔ lɔng tɛm, di liva tisu kin gɛt skata ɛn di liva kin at. Wi kin kɔl dis sik we dɛn kɔl sirosis . Bikɔs ɔf dis kɔndishɔn, di blɔd we de go na di liva kin chenj, ɛn as tɛm de go, di liva kin stɔp fɔ wok.

Dɔn bak, if i gɛt akyu liva fayl we kin apin wantɛm wantɛm bikɔs ɔf sɔm rizinBɔt, HRS kin apin. Stɔdi dɔn sho se HRS kin apin to 40% pan pipul dɛm wae gɛt ɛnd-stej liva sik. Pan ɔl we i kin apin pan ɛni ej ɛn man ɔ uman, i kin apin mɔ pan pipul dɛn we de na dɛn sɛkɔn pat na dɛn layf. I kin apin bak pan lɛk 10% pan di pipul dɛm wae de na ɔspitul wit krɛse ɔr akyu liva fayl. Pan ɔl we pas wan tin de we kin mek pɔsin in kidni nɔ wok fayn bikɔs ɔf di liva sik, HRS spɛshal bikɔs i kin apin to pipul dɛn we nɔ gɛt ɛni sik na dɛn kidni bifo.

Aw sirosis kin mek pɔsin gɛt ɛpatɔrɔnal sindrom?

Dis na smɔl tin we kɔmplikt. Difrɛn opinion stil de bitwin di wan dɛn we de stɔdi bɔt aw di liva sik kin mek pɔsin gɛt ɛpatorenal syndrome (HRS), dat na di pathophysiology .

Aw dis kin rili apin? (Patofisiɔlɔji) .

As wi no, di kidni fεil kin apin we di blɔd vesel dεm na di kidni dεm kin sכmtεm, blכk, εn di blɔd fכ fכlכ to dεm kin rεdכks. Risach pipul dɛn biliv se dis we aw di blɔd vesel dɛn kin smɔl, na bikɔs ɔf tin dɛn we kin mek pɔsin gɛt sik na di liva ɛn di liva we nɔ de wok fayn. Di men tin we kin mek dis apin na di pɔtal haypatɛnshɔn .

Pɔtal haypatɛnshɔn na wan sik we di blɔd prɛshɔn na di pɔtal vein, di men vein we de rɔn tru yu liva, ɛn di vein dɛn we de kɔnɛkt to am ɛn go ɔlsay na yu dijestiv sistɛm, de go ɔp. Di tin we kin mek dis sik pas ɔl na sirosis . Sirosis kin mek yu gɛt wan sik bak we dɛn kɔl cirrhotic cardiomyopathy , we kin mek sɔm pan di at dɛn na yu bɔdi nɔrmal. Dis kɔmpleks chenj we di blɔd de flɔ kin mek sɔm blɔd vesel dɛn big we ɔda wan dɛn (espɛshali di wan dɛn we de na yu kidni) kin smɔl. Tink bɔt am lɛk we trafik jam na wan say na rod, we kin afɛkt di ɔda say dɛn bak.

Wetin na di tin dɛn we kin mek dis tin wɔs kwik kwik wan?

Ɔda tin dɛn de we gɛt fɔ du wit di liva sik we kin bi "trig" ɔ prɛsipitayt factor fɔ HRS. Di wan we kin bɔku pan dɛn wan ya na Spɔntan Bakterial Pɛritonaytis (SBP) . dis na baktriyal infεkshכn na di layn na yu bכdi (pεritoneum). SBP na wan kɔmplikeshɔn fɔ ascites , we na we wata we de bɔku na di bɛlɛ. di asita de kכz fכ di wata we de lik frכm di vein dεm na di bכdi bikoz fכ di pכtal haypatεnshכn.

Imagine, if your abdomen is filled with water (ascites), germs can easily enter there and cause an infection. na dat dεn kכl dis spontan baktriyal pεritonaytis (SBP).

Dɔn bak, pɔtal haypatɛnshɔn kin mek yu vein dɛn bɔs ɛn blɔd go insay yu bɛlɛ. Lɛk dis:Akyu blɔd we de lɔs bikɔs ɔf di blɔd we de kɔmɔt na di bɛlɛ na ɔda tin we kin mek i gɛt dis sik. Nɔto dat nɔmɔ, bɔt fɔ yuz pasmak diuretics , ɔ "wata pills," kin bi bak wan rizin. Diuretics de wok bay we dɛn de pul di wata we pasmak na di bɔdi. Pipul wae gɛt advans liva sik kin tek dɛn wata pils ya fɔ ascites ɔ edema , we na we de swel na dɛn bɔdi.

Wetin na di sayn dɛm we de sho se yu gɛt dis sik?

Pipul wae gɛt hepatorenal syndrome (HRS) kin fɔs gɛt wan vague, jenɛral filin fɔ nɔr wɛl. Di sayn dɛm na:

• Taya
• Vɔmit
• Bɛlɛ de at
• Bad taste na di mɔt

Apat frɔm dat, dɛn kin gɛt sayn dɛn bak we de sho se dɛn gɛt sik na dɛn liva we dɔn go bifo ɔ dɛn liva nɔ de wok fayn. Dɛn tin ya na:

• Jaundice (we di wayt na di yay dɛn de yɔlɔ) .
• I izi fɔ brus ɛn blɔd
• Stul dɛn we gɛt layt kɔlɔ ɛn urine we gɛt dak kɔlɔ
• Bεlε de swεla (bikɔs ɔf ascites, wan liva ɔ splin we dɔn big) .
• Skin we de it
• Kɔnfyushɔn, mɛmori lɔs, ɔ slip (Hepatic Encephalopathy) .

We yu kidni nɔ de wok fayn, yu go notis se di urine we yu de mek dɔn go dɔŋ bad bad wan .

Aw yu no dis?

Hepatorenal syndrome (HRS) na wan kayn kidni fεil we kin apin we yu gεt siriכs liva sik εn nכ כda tin we kin mek di kidni fεil. So, dɔktɔ dɛn kin no dis bay we dɛn kin fɔs kɔnfɔm se di liva sik ɛn di kidni nɔ de wok fayn, dɔn dɛn kin pul ɔda tin dɛn we kin mek di kidni nɔ wok fayn. Fɔ du dis, dɛn kin yuz difrɛn difrɛn tɛst dɛn we dɛn kin yuz fɔ mek pikchɔ dɛn , lɛk skan, blɔd tɛst, ɛn urine tɛst fɔ chɛk aw yu liva ɛn kidni dɛn de wok.

Aw dɛn kin trit am?

Pan ɔl we HRS na rili siriɔs sik bikɔs di kidni dɛn nɔ de wok fayn, di rut fɔ di prɔblɛm de na di liva . di hεpatorenal sεndrכm (HRS) dεn kכl am "prεrenal" fכm fכ akyu kidni fεil biכs yu kidni dεm כda we de hεlty. Infakt, if dɛn tek yu kidni ɛn transplant am na ɔda pɔsin in bɔdi, i go wok fayn fayn wan. Semweso, if yu liva wok bak lɛk aw i bin de wok, chans de fɔ mek yu kidni dɛn bigin fɔ wok bak.

Sɔm pipul dɛm wae gɛt akyu liva fail kin gɛt bak dɛn liva ɛn kidni fɔ wok fayn fayn wan. Bɔt ɔlman go nid fɔ gɛt liva transplant . Dɛn kin nid fɔ gɛt liva transplant sɔm tɛm ɛni we, bɔt HRS kin mek di nid fɔ du am kwik kwik wan. Bɔt nɔto ɔlman kwalifay fɔ gɛt liva transplant, ɛn ivin if dɛn du am, dɛn fɔ wet te dɛn gɛt wan.

Na dis kayn tɛm, fɔ trit pɔsin kwik kwik wan ɛn fɔ mɛn am di rayt we na di tin dɛn we impɔtant pas ɔl.

Insai dis tɛm, yu dɔktɔ ɔr nɔs go tray fɔ mek yu kidni nɔ wok fayn ɛn ridyus di sayn dɛm ɛn sayd ɛfɛkt dɛm fɔ dis sik. Dɛn step ya kin mek yu ɔl gɛt wɛl bɔdi ɛn ɛp fɔ rɛdi yu fɔ transplant yu liva. Dɛn kin ɛp bak fɔ mek di liva transplant fayn if yu gɛt am. Bɔt dɛn tin ya nɔto mɛrɛsin . Dɛn tritmɛnt ya kin bi:

• Dɛn kin gi IV fluid , we na tin dɛn lɛk salin, fɔ kɔrɛkt di ilɛktrɔlayt dɛn we nɔ balans na di bɔdi ɛn ɛp fɔ mek di blɔd go na di kidni dɛn.
• Fɔ stɔp sɔm mɛrɛsin dɛn, lɛk diuretics (wata pills).
• Gi antibayɔtik fɔ infɛkshɔn dɛn we gɛt fɔ du wit am.
• di paracentesis dεn de du fכ pul di εksyכs fכ fכm we dεn kכlכm bikoz fכ di ascites.
• Fɔ gi mɛrɛsin dɛn we dɛn kɔl vasoconstrictors . Dɛn tin ya kin wok bay we dɛn kin mek yu blɔd vesel dɛn we nɔ kin wayd ɛn mek di blɔd go na di kidni dɛn mɔ ɛn mɔ.
• Hemodialysis , we na blɔd dayalaysis, na tritmɛnt fɔ ɛp yu kidni dɛm we gɛt strɛs.

Yu tink se dɛn go ebul fɔ stɔp am?

Di bɛst we fɔ mek yu nɔ gɛt ɛpatorenal syndrome (HRS) na fɔ kɔntrol di liva sik bifo i go to sirosis . Krεse sik na wan sik wae de kam sloslo fɔ plεnti ia. Pipul wae no se dεn gεt dis sik kin kכntro εn sכmtεm dεn kin rεvεs di prכgrεs fכ de sik bay wae dεn de du tin dεm lεk fכ kכt dכn rכk, lכs dεn wet, εn fכ mek dεn it fayn. Bɔt bikɔs bɔku pipul dɛn nɔ kin sho di sik, dɛn nɔ kin no am if dɛn nɔ du dɔktɔ ɛgzam ɔltɛm.

If yu dɔn gɛt sirosis, no we nɔ de fɔ no ɔ fɔ mek HRS nɔ kam. Bɔt, Spɔntan Bakterial Pɛritonaytis (SBP) .Dat se, yu kin avɔyd di mɔs kɔmɔn "trig" fɔ dis. SBP na in de ripɔtabl fɔ lɛk 25% pan di kes dɛm fɔ HRS pan pipul dɛm wae gɛt sirosis. So, if yu dɔktɔ tink se yu de pan ay risk fɔ gɛt SBP, fɔ tek antibayɔtik as prɛvɛntiv mɛsej kin ridyus dis trig ɛn ridyus yu chans fɔ gɛt HRS.

Yu tink se dɛn go ebul fɔ mɛn dis? Yu tink se i de mek pɔsin in layf de pan denja?

If dɛn nɔ transplant dɛn liva, bɔku pipul dɛn kin gɛt siriɔs sik. If HRS wɔs wantɛm wantɛm ɛn dɛn nɔ ebul fɔ transplant am, di avɛrej tɛm we pɔsin kin liv na tu wiks nɔmɔ . Wit kronik HRS, di avrej tɛm fɔ liv we dɛn nɔ transplant na tri to siks mɔnt . Dipen pan aw di liva de wok tranga wan, de sik kin wɔs kwik kwik wan. Dɔn bak, if di sik wɔs kwik kwik wan, yu kin sik tumɔs fɔ mek dɛn transplant yu, ɛn dis kin tranga.

Bɔt if dɛn transplant yu liva, yu sik go rili bɛtɛ . Pipul wae gɛt HRS gɛt 60% chans fɔ liv tri ia afta dɛn dɔn transplant dɛn liva. Dis sכmtεm sכmtεm pas di tri ia rεt fכ pipul dεm we kin gεt liva transplant (75%). Bɔrku pipul dɛn kidni wok go kam bak to nɔrmal insay sɔm wiks. Wan rili smɔl nɔmba (lɛk 5%) kin nid fɔ kɔntinyu fɔ dayalaysis .

Ilɛksɛf yu na pɔsin we gɛt di ɛnd-stej liva we de pwɛl smɔl smɔl ɔ we gɛt ɛpatorenal sindrom (HRS) we de bigin wantɛm wantɛm we mek yu tɛm kwik, fɔ de na di liva we de wet fɔ di wan dɛn we de gi yu liva nɔto fayn tin. Na bikɔs nɔto inɔf dona liva de fɔ pipul dɛn we de na da list de. Bɔt if yu ebul fɔ fɛn pɔsin we de gi yu liva we de alayv , yu nɔ go nid fɔ de pan di list, ɛn yu ɔl wɛlbɔdi biznɛs kin bɛtɛ.

Di wan dɛn we de gi di blɔd we de alayv na volontia dɛn we gɛt wɛlbɔdi, bɔku tɛm na di wan dɛn we yu lɛk, we fit fɔ yu blɔd tayp ɛn yu bɔdi saiz. Ivin smɔl pat pan di liva we dɛn tek frɔm ɔda pɔsin we gɛt layf kin gro bak to kɔmplit liva insay yu ɛn di pɔsin we gi am. Dɔn bak, i go mɔs bi se di liva dɛn we de alayv go bɛtɛ pas di liva dɛn we dɛn tek frɔm di wan dɛn we dɔn day. Di dɔktɔ dɛn we de du ɔpreshɔn kin tray tranga wan fɔ mek di ɔpreshɔn pan dɛn heroic living donors ya nɔ gɛt bɛtɛ invasive as dɛn ebul.

Fɔ dɔn, tin dɛn we wi fɔ mɛmba

So, yu go dɔn ɔndastand naw se di ɛpatɔrɔnal sindrom na siriɔs sik we nid fɔ pe atɛnshɔn bikɔs i kin afɛkt di kidni dɛn bikɔs ɔf di liva prɔblɛm.

• Liva wɛlbɔdi rili impɔtant:If yu gɛt ɛni sik na yu liva, i rili impɔtant fɔ manej am fayn, mɔ fɔ mek i nɔ go bifo to sik lɛk sirosis.
• Pe atɛnshɔn to di sayn dɛm: If yu gɛt sɔm sayn dɛm wae gɛt fɔ du wit liva sik ɔr yu de fil lɛk yu nɔr wɛl, go to dɔktɔ kwik kwik wan.
• Tink bɔt yu kidni: We yu gɛt prɔblɛm wit yu liva, yu nid fɔ tek kia ɔf yu kidni bak. If yu gɛt sayn dɛn lɛk we yu nɔ de pis, tɛl yu dɔktɔ.
• Tritmɛnt de: Pan ɔl we HRS na siriɔs sik, tritmɛnt lɛk fɔ transplant liva kin sev pipul dɛn layf. So nɔ giv ɔp fɔ gɛt op.
• Di we aw yu de liv yu layf impɔtant: Tin dɛn lɛk fɔ liv fayn layf, fɔ it tin dɛn we nɔ fayn, ɛn fɔ avɔyd fɔ drink rɔm kin ɛp fɔ mek di liva gɛt wɛlbɔdi.

A op se dis infɔmeshɔn go ɛp yu. If yu ɔ pɔsin we yu sabi gɛt dis kayn prɔblɛm, di bɛst tin fɔ du na fɔ go to dɔktɔ wantɛm wantɛm.

` Epatorenal sεndrכm, liva sik, kidni fεil, sirosis, liva transplant, pכtal haypatεnshכn, ascites