Yu pikin gɛt lumps na in bon? Lɛ wi lan bɔt HMO (Hereditary Multiple Osteochondromas)!

Yu go dɔn notis smɔl smɔl smɔl smɔl smɔl smɔl smɔl smɔl smɔl smɔl smɔl smɔl smɔl smɔl smɔl smɔl smɔl smɔl smɔl smɔl smɔl smɔl smɔl smɔl smɔl smɔl smɔl smɔl smɔl smɔl smɔl smɔl smɔl smɔl smɔl smɔl smɔl smɔl smɔl smɔl smɔl smɔl smɔl smɔl smɔl smɔl smɔl smɔl smɔl smɔl smɔl smɔl smɔl smɔl smɔl smɔl smɔl smɔl smɔl smɔl smɔl smɔl smɔl smɔl smɔl smɔl smɔl smɔl smɔl smɔl smɔl smɔl smɔl smɔl smɔl smɔl smɔl smɔl smɔl smɔl smɔl smɔl smɔl smɔl smɔl smɔl smɔl smɔl. Sɔntɛnde, dɛn tin ya kin mek pɔsin fil pen ɔ nɔ kin mek i fil pen. Nɔ wɔri , nɔto ɔl lumps denja. Bɔt tide wi go tɔk bɔt wan sik we de sho dɛn kayn sik ya, we nɔ kin rili kɔmɔn bɔt i rili impɔtant fɔ mek wi ɔl no bɔt. dis kכndyushכn dεn kכl am HMO, we tinap fכ `Hεreditary Multiple Osteochondromas`.

Wetin na HMO (Hɛritɛri Mɔltipɛl Ɔstiɔkɔndrɔmas)?

Fɔ tɔk am simpul wan, HMO na wan sik we pɔsin kin gɛt frɔm in jɛnɛtiks . Na smɔl chenj, ɔ muteshɔn, na wi jin, ɔ di men blueprint we de sho aw wi bɔdi de gro, kin kam. Dis chenj kin mek sɔm pan wi bon dɛn gɛt benign, ɔ nɔ bad, tumbu , we wi kin kɔl ɔsteochondroma , we dɛn kin kɔl ɔsteochondroma , ɛn dɛn kin bigin fɔ gro bɔku bɔku wan. Dɛn tin ya nɔto rili kansa, so natin nɔ de fɔ wɔri bɔt.

Yu tink se ɔda nem dɛn de fɔ dis HMO?

Yɛs, yu kin kam fɔ no sɔm ɔda nem dɛn we yu de luk fɔ dis sik. Sɔntɛnde, dɔktɔ dɛn kin yuz dɛn nem ya:

• `Hɛridit Mכltipl כstiokכndrכmas (HMO)` (dis na di wan we dεn kin yus mכst naw)
• `Multiple Hereditary Exostoses` (bifo dis na bin di nem we dɛn kin kɔl pas ɔl)
• `Diaphyseal aklasis`

I nɔ mata us nem yu yuz, na di sem mɛrɛsin. So if yu si wan pan dɛn nem ya, nɔ kɔnfyus, okay?

So wetin na dis ɔstiɔkɔndroma?

Osteochondroma, lɛk aw a bin dɔn tɔk, na wan bɔdi we nɔ gɛt kansa, in ɔda wɔd dɛn, we nɔ gɛt wan prɔblɛm . Imajin, dɛn tumbu ya kin fɔm we di sɛl dɛn na wi bon dɛn, instead fɔ gro nɔmal wan, bigin fɔ gro difrɛn smɔl, we nɔ kin gro.

dis tכmכro dεm kin kכmכt na di flat say na di bon כ insay di fleksibul tisu we dεn kכl kכtilaj we de na di εnd dεm na di bon dεm, we dεn kכl growth plet, we de εp pikin dεm fכ gro εn dεn bon dεm de gro. dis tכmכro dεm de kכba bak wit wan katilej kכp. Di impɔtant tin na dat dɛn nɔ gɛt kansa , so dɛn nɔ de skata ɔlsay na di bɔdi. Yu nɔ tink se dat kin mek pɔsin fil fayn?

Udat kin gɛt dis sik? Aw i kɔmɔn?

Dɔktɔ dɛn kin no se i gɛt HMO we dɛn smɔl ɔ we dɛn yɔŋ . I kin afɛkt bɔy pikin ɛn gyal pikin dɛn ikwal.

Bɔt HMO nɔto wan sik we kin rili kɔmɔn . Fɔ tɔk smɔl, i kin afɛkt lɛk wan pan ɛvri 50,000 pipul dɛn. So i nɔ go sɔprayz if yu nɔ yɛri bɔt am.

Wetin kin mek pɔsin gɛt HMO? Yu tink se sɔntin de we gɛt fɔ du wit di jɛnɛtiks?

Yɛs, HMO na sik we pɔsin kin gɛt we i kam pan jɛnɛtiks . Dat min se i gɛt fɔ du wit wi jin dɛn.

Naynti pasεnt (90%) pan pipul dεm we gεt HMO de divεlכp am if chenj, כ m כtεshכ n , de na di jin dεm we dεn kכl `EXT1` כ `EXT2` (dεn jin dεm ya na di instrכkshכn dεm na wi `DNA` we de tεl wi bכdi aw fכ mek sכm imכtant protin dεm). כnכfכs, dεn nכ fכnshכn di εksakεt jεnεtik kכz we de afekt di כda 10 pasεnt (10%) .

Bɔku tɛm , dɛn jɛnɛtik chenj ya kin kɔmɔt frɔm mama ɛn papa to pikin dɛn . Dis min se if di mama ɔ papa gɛt di muteshon, di pikin kin gɛt am bak. Bɔt sɔm pipul dɛn we gɛt HMO nɔ gɛt ɛni wan pan dɛn mama ɛn papa we gɛt di muteshon. Dis min se ivin if nɔbɔdi na di famili nɔr gɛt HMO, sɔmtɛm pɔrsin kin gɛt dis sik fɔ di fɔs tɛm. Dɛn kɔl dis nyu muteshon.

Wetin na di sayn dɛm fɔ HMO? Us kayn tin yu de si?

HMO kin mek lump dɛn we de mek yu fil pen pan wan ɔ mɔ bon dɛn. Dɛn kɔl dɛn lumps ya ɔsteochondroma. Apat frɔm dat, yu kin gɛt sɔm sayn dɛn lɛk:

• di bon dεm we nכ de gro , inklud di chenj dεm na di bon dεm na di fכs an. Sɔntɛnde, di an kin tan lɛk se i lɔng smɔl.
• Bɔn dɛn kin brok bɔku tɛm ɛn di growth plet kin brok.
• Difrɛns we di limb lɔng . Tink bɔt wan leg shɔt smɔl pas di ɔda wan, ɔ wan an shɔt pas di ɔda wan.
• Nɔ ebul fɔ muv di jɔyn dɛn fayn fayn wan, yu kin fil se di jɔyn dɛn stif.
• di nεv dεm we dεn pinch kin bi fכ di bon spur dεm, we kin mek yu sכmtεm sכmtεm sכmtεm εn pen.
• Premature osteoarthritis , we min se yu fɔ wɛr joyn bifo tɛm we yu yɔŋ.
• Prɔblɛm wit anklɛ ɔ ni, pen we yu de waka.
• Pen fɔ shɔt tɛm ɛn fɔ lɔng tɛm . Sɔntɛnde, dis pen kin at fɔ bia.
• Short ayt .

Sɔm pikin dɛn kin fil mɔ pen we dɛn tumbu ya de kam nia di blɔd vesel ɔ di nerv dɛn. Bɔt sɔntɛnde, dɛn tumbu ya nɔ kin gɛt pen ɛn dɛn kin jɔs tan lɛk wan lump.

Impɔtant: If yu si ɛni lumps lɛk dis na yu pikin in bɔdi, ɔ if yu pikin kin kɔmplen bɔku tɛm se in bon de pen, duya go to dɔktɔ.

Dis HMO kɔndishɔn kin pas frɔm wan pɔsin to ɔda pɔsin?

Nɔ, HMO nɔto sik we pɔsin kin pas . Dat min se i nɔ de skata frɔm wan pɔsin to ɔda pɔsin bay we i tɔch ɔ de nia am, lɛk kol. Na wan sik we pɔsin kin gɛt we i kam pan jɛnɛtiks.

Bɔt if yu gɛt HMO, na lɛk 50% chans de fɔ mek yu pas di jin muteshon we de mek dis sik to yu pikin.Yɛs. Dat min se 50% chans de insay ɛvri bɛlɛ.

Aw dɔktɔ dɛn kin no if pɔsin gɛt HMO?

Yu ɔ yu pikin in dɔktɔ kin notis wan lump pan ɔ nia wan bon, ɔ ɔda sayn dɛm fɔ HMO (e.g., smɔl swel, pen). Dɔktɔ dɛn go fɔs:

1. Fɔ tek tɛm aks bɔt di famili in mɛrɛsin istri . Fɔ chɛk fɔ si if ɛnibɔdi na di famili dɔn gɛt dis sik.

2. Wan kɔmplit ɛgzam fɔ di bɔdi . Fɔ chɛk fɔ si if dɛn gɛt lumps, dɛn saiz, ɛn fɔ muv di jɔyn dɛn.

Us kayn mɛdikal tɛst dɛn kin du?

Afta dɛn dɔn chɛk dɛn bɔdi, dɔktɔ dɛn kin se dɛn fɔ du imej tɛst fɔ no if HMO de.

• Bɔku tɛm, di fɔs tin we dɛn kin du na fɔ tek ɛkstrem rayt . X-ray kin sho klia wan dɛn ɔstiochondroma tumor dɛn ya.
• Sɔntɛnde, fɔ no mɔ bɔt di tumbu, ɔ fɔ si if i de afɛkt tin dɛn lɛk di nerv, yu kin nid fɔ du dɛn tɛst ya bak:
• `CT skan`
• `MRI` (M.R.I.) ɛn di ɔda wan dɛn.

Na di infɔmeshɔn we dɛn kin gɛt frɔm dɛn tɛst ya kin mek dɔktɔ dɛn no if dɛn fɔ gɛt HMO ɔ dɛn nɔ fɔ gɛt am.

Aw dɛn kin trit HMO? Wetin na di tin dɛn we yu go ebul fɔ du?

Di tritmɛnt fɔ HMO nɔto di sem fɔ ɔlman. I dipen pan di sayn dɛm we yu gɛt, di nɔmba fɔ di tumbu dɛm, usay dɛn de, ɛn di ifɛkt dɛm we dɛn gɛt . Dɔktɔ dɛn kin tɛl yu fɔ gi yu tritmɛnt dɛn lɛk:

• Wach di tumbu / wachful wet: Sɔntɛnde, if di tumbu nɔ de kɔz ɛni big prɔblɛm ɔ pen, dɔktɔ dɛn kin se yu fɔ wet fɔ sɔm tɛm fɔ si if di tumbu de gro ɔ mek ɛni prɔblɛm. Dɛn kɔl dis "watchful waiting."
• aw fɔ kɔntrol di pen: If pen de, dɛn kin gi am mɛrɛsin (lɛk paracetamol ɔ ibuprofen) fɔ kɔntrol am. Sɔntɛnde, dɛn kin nid fɔ yuz mɛrɛsin dɛn we strɔng fɔ mek pɔsin fil pen.
• Fizik tritmɛnt: Fizik thɛrapist kin tich ɛksesaiz fɔ ɛp fɔ mek di jɔyn dɛn kɔntinyu fɔ muv ɛn fɔ mek di mɔsul dɛn strɔng. Dis kin ɛp bak fɔ ridyus di pen.
• Ɔpreshɔn:
• Ɔpreshɔn fɔ pul wan ɔ mɔ tumbu: If di tumbu de mek pɔsin fil pen we i nɔ ebul fɔ bia, i de prɛs pan wan nerv, i de ambɔg di muvmɛnt fɔ wan jɔyn, ɔ if pɔsin tink se di tumbu kin gɛt kansa, dɛn kin ɔpreshɔn di tumbu.
• Ɔpreshɔn fɔ mek di limb dɛn we nɔ de gro fayn ɔ lɔng ɔ stret: If dɛn shɔt ɔ strɛch wan an ɔ leg bikɔs ɔf HMO, spɛshal ɔpreshɔn dɛn de fɔ kɔrɛkt am.

Yu tink se prɔblɛm dɛn kin apin we dɛn de trit am?

Sɔm pipul dɛn we dɛn kin du ɔpreshɔn fɔ pul di ɔstiochondroma tumor dɛn kin gɛt skata.Jɔs lɛk ɛni ɔpreshɔn, smɔl risk de fɔ mek pɔsin gɛt infɛkshɔn ɔ fɔ mek di nerv pwɛl. Bɔt, dɔktɔ dɛn kin du ɔl wetin dɛn ebul fɔ mek dɛn prɔblɛm dɛn ya nɔ bɔku.

I gɛt we fɔ avɔyd di HMO sityueshɔn?

Fɔ tru, natin nɔ de we yu go du fɔ mek yu nɔ gɛt HMO bikɔs na jenɛtik kɔndishɔn.

Bɔt if yu no se sɔmbɔdi na yu famili gɛt HMO, ɛn yu de op fɔ bɔn pikin, yu kin tink bɔt fɔ du di jenɛtik tɛst bifo yu bɔn we yu gɛt bɛlɛ fɔ no if yu pikin dɔn gɛt di sik. Fɔ ɛgzampul:

• ``Kɔriɔnik Vilɔs Sampling (CVS)''.
• `Jɛnɛtik amniocentesis`

dis tεst dεm kin εp fכ no if di εmbrayo gεt HMO bifo tεm. Sɔntɛnde, if yu de yuz atifishal inseminɛshɔn we (lɛk IVF), prɛ-implant jenɛtik tɛst kin bi bak wan opshɔn. Tɔk to yu dɔktɔ bɔt dis fɔ no mɔ.

Aw a go no if mi pikin de pan denja fɔ gɛt HMO?

If yu, yu man/wɛf, ɔ yu fambul we de nia yu gɛt HMO, i rili impɔtant fɔ tɛl yu dɔktɔ bɔt am, bikɔs di pikin sɛf kin de pan denja.

If no famili histri nɔ de, di risk fɔ mek pikin gɛt HMO rili smɔl. Bɔt, lɛk aw a bin dɔn tɔk, i kin bi bak bikɔs ɔf nyu muteshon, so i nɔ kin izi fɔ du am atɔl.

Wetin a kin ɛkspɛkt if mi pikin gɛt HMO?

If yu pikin gɛt HMO, di sik kin difrɛn frɔm wan pikin to ɔda pikin. Sɔm pikin dɛn kin gɛt jɔs sɔm ɔstiochondroma tumor, ɔ dɛn kin gɛt bɔku tumor.

di gud nyus na dat , bכku tεm, afta di pikin in growth plet dεm klos, we min se di pikin in ayt εn in bon lεngth stכp fכ inkrεs, dεn tכmכro dεm ya nכ go gro igen.

Bɔt fɔ sɔm pipul dɛn, ivin afta di plet dɛn we de gro dɔn lɔk, dɛn kin kam bak. I de rare smɔl.

HMO kin mek ɔda sayn dɛn bak. Sɔm pikin ɛn big pipul dɛn kin taya , fil pen, ɛn i nɔ kin izi fɔ muv dɛn bɔdi ɔ du wok.

Nɔto ɔlman we gɛt HMO go nid tritmɛnt. Bɔt sɔm kin nid ɔpreshɔn ɔ tritmɛnt fɔ dɛn bɔdi. Dɔktɔ dɛn kin tɛl yu bak fɔ tek mɛrɛsin ɔ ɔda tritmɛnt dɛn fɔ ɛp fɔ kɔntrol di pen.

Aw lɔng dis tin go las?

HMO na wan sik we pɔsin kin gɛt fɔ ɔl in layf . Dis min se i nɔ go ebul fɔ wɛl ɔl. Bɔt bɔku pipul dɛn we gɛt dɛn benign ɔsteochondromas ya kin gɛt nɔmal layf we dɛn kin liv .I pɔsibul fɔ liv. Di tin we impɔtant pas ɔl na fɔ kɔntrol di sik dɛn, gɛt di tritmɛnt we yu nid, ɛn kɔntinyu fɔ gɛt gud kwaliti layf. Ɔltɛm tɔk to yu dɔktɔ bɔt di tritmɛnt we go ɛp yu pikin fɔ gɛt wɛlbɔdi ɛn gladi at.

Yu tink se di ɔsteochondroma tumor dɛn kin bi kansa? Dis na wetin bɔku pipul dɛn kin fred.

Dis na rili impɔtant kwɛstyɔn. Yes, very rarely , dat na, very rarely , ɔsteochondroma tumors na pipul dɛm wae gɛt HMO kin bi malignant. Bitwin 2% ɛn 5% pan pipul dɛm wae gɛt HMO (dat na bitwin 2 ɛn 5 pan 100) kin gɛt dis kayn kansa. we dis apin, dεn benign tכmכro dεm ya de tכn to bon kεnsar dεm we dεn kכl `chondrosarcoma` כ `osteosarcoma`.

Yu dɔktɔ kin tink se ɔsteochondroma kin gɛt kansa if:

• If yu pikin gɛt nyu mɔl afta we i dɔn yɔŋ , ɔ if wan mɔl we dɔn de bigin fɔ gro kwik kwik wan wantɛm wantɛm.
• If wan ɔsteochondroma we nɔ bin de pen bifo, de fil pen wantɛm wantɛm , ɔ if di pen we bin dɔn de bigin fɔ fil bad bad wan.
• if di katilej kap we de pan tap pan tכmכro tik pas 2 sεntimita (dεn kin si dis wit MRI skan).

Dɛn kin pul bɔku pan di tumbu dɛn we gɛt kansa bay we dɛn du ɔpreshɔn. Dipen pan di stej we di kansa gɛt, if i dɔn skata (metastasized), yu pikin nɔ go nid ɔda tritmɛnt (lɛk kemotɛrapi ɔ rediotɛrapi). Na dat mek i impɔtant fɔ mek yu de chɛk yu ɔltɛm.

Aw fɔ kia fɔ pikin we gɛt HMO? Wetin wi go du as mama ɛn papa?

If yu pikin gɛt HMO, i rili impɔtant fɔ pe atɛnshɔn to di sik dɛn we yu pikin gɛt .

• If yu pikin gɛt ɛni nyu sayn , mɔ di sayz we di bɔdi chenj wantɛm wantɛm, i de fil pen mɔ ɛn mɔ, ɔ i nɔ de fil fayn, tɛl yu dɔktɔ wantɛm wantɛm.
• Fɔ fala di dɔktɔ in instrɔkshɔn dɛn gud gud wan (aw fɔ tek yu mɛrɛsin, aw fɔ ɛksesaiz, ɛn ustɛm fɔ kam fɔ tɛst).
• If yu pikin de fil pen, nɔ mek dɛn bia am. Tɔk to yu dɔktɔ ɛn fɛn we fɔ kɔntrol di pen.
• Tink bɔt yu pikin in maynd wɛl bɔdi bak. Sɔntɛnde, fɔ liv wit dis kayn tin kin tranga fɔ pikin. Tɔk to yu pikin, sɔpɔt yu pikin.

Ustɛm a fɔ go to dɔktɔ if mi pikin gɛt HMO? Wetin na di imejensi dɛn?

If dɛn dɔn no se yu pikin gɛt HMO, go to dɔktɔ wantɛm wantɛm pan dɛn kayn tin ya:

• If di pikin gɛt nyu tumbu dɛn .
• If yu fil lɛk se wan lump de big wantɛm wantɛm .
• If di pen go ɔp wantɛm wantɛm ɔ if nyu, bad bad pen kam (espɛshali afta yu dɔn rich di pikin).
• Usay wan lump deIf di skin rεd, swεla, εn fil wam (dis kin bi sayn fכ infεkshכn).
• If yu gɛt swɛt ɔ wik na yu an ɔ yu leg.

Nɔ ignore dɛn sayn ya. If yu go to dɔktɔ kwik kwik wan, dat kin mek big big prɔblɛm nɔ kam.

Pikin dɛm wae gɛt HMO kin gɛt ɔtizm?

Sɔm mama ɛn papa dɛn kin aks bɔt dis bak. di mεdikal masta sabi pipul dεm dכn ripot sεvεra kes dεm we pikin dεn gεt HMO εn wan kכndyushכn we dεn kכl `autism spectrum disorder`. Bɔt dɛn stil nɔ no fɔ tru if wan patikyula, dairekt link de bitwin di tu kɔndishɔn dɛn. Risach pipul dεm stil de stכdi if di jεnεtik mכtεshכn dεm (`EXT1`, `EXT2` jin dεm) we de mek HMO de kכntribyut bak fכ divεlכp כtizm. Naw, dɛn nɔ dɔn rich ɛni strɔng kɔnklushɔn bɔt dis.

Fɔ dɔn, di tin dɛn we impɔtant pas ɔl we yu fɔ mɛmba

HMO, we tinap fכ `Hereditary Multiple Osteochondromas` (sכmtεm dεn kin kכl am `Multiple Hereditary Exostoses`), na jεnεtik kכndishכn we benign tכmכro dεm (osteochondromas) de fכm along di bon dεm εn insay di growth plet dεm fכ pikin dεm εn yכng big pipul dεm.

Pan ɔl we HMO na sik we pɔsin kin gɛt fɔ ɔl in layf, i kin mek pɔsin fil pen ɛn chenj in skel. Bɔt tritmɛnt dɛn lɛk ɔpreshɔn, fyzikal tritmɛnt, ɛn aw fɔ mɛn yu pen kin rili pul di sik dɛn, kɔrɛkt di bon dɛn we nɔ fayn, ɛn ɛp yu fɔ liv gud layf.

Di tin we impɔtant pas ɔl na fɔ nɔ panik ɔ panik if yu pikin gɛt dɛn sik ya, bɔt fɔ go to dɔktɔ we sabi du di wok kwik kwik wan. Tɔk wit di dɔktɔ opin wan ɛn disayd us tɛst yu pikin nid ɛn wetin na di bɛst tritmɛnt. Yu sɔpɔt ɛn ɔndastandin go bi big trɛnk fɔ yu pikin fɔ liv fayn fayn wan wit dis sik.

` Hεreditary Multiple Osteochondromas, Multiple Hereditary Exostoses, Osteochondromas, Bon Tכmכr, Jεnεtik Sik, Pikin dεm Sik, Bon Pen