Yu kin si se ivin nɔmal pen nɔ kin ebul fɔ bia? Lɛ wi tɔk bɔt Hyperalgesia!

Imajin se yu gɛt smɔl bɔn na yu an we yu de wok na kichin. Ɔ yu gɛt smɔl skrach we yu de ple kriket. Na nɔmal tin fɔ fil smɔl pen sɔntɛnde lɛk dis. Bɔt wetin yu go du if da smɔl pen de tɔn to pɔsin we yu nɔ go ebul fɔ bia, so bad dat yu go fil lɛk fɔ ala? Na di kɔndishɔn we wi de tɔk bɔt tide, `Hyperalgesia`. Dis na sayn pas sik. Lɛ wi tɔk bɔt dis smɔl mɔ .

Wetin na hyperalgesia simpul wan?

Pen na rili wɛlbɔdi, nɔmal pat na wi bɔdi. I tan lɛk wan bɛl we de wɔn pipul dɛn. Pen de tɛl wi se sɔntin nɔ fayn, sɔmtin nɔ fayn wit wi bɔdi. We wi fil pen, wi kin ansa am ɔtomɛtik wan, ɛn tray fɔ stɔp di pen. Imajin aw bɔku siriɔs aksidɛnt dɛn wi kin gɛt if wi nɔ fil pen.

Hyperalgesia na wan sik wae de fil pen na wan lɛvɛl wae de pasmak pas aw i fɔ bi, ivin we i fɔ bi. Fɔ tɔk am simpul wan, di we aw pɔsin kin fil we i de fil pen kin bɔku. Dis kin kam bikɔs ɔf difrɛn rizin, ɛn bɔrku tɛm dɛn kin kɔntrol am wit di rayt tritmɛnt.

Wetin na di difrɛns bitwin Hyperalgesia ɛn Allodynia?

Pan ɔl we dɛn tu wɔd ya fiba smɔl, difrɛns de bitwin dɛn tu tin ya. Fɔ ɔndastand dis klia wan, luk di tebul we de dɔŋ ya.

Yu ɔndastand di difrɛns? Na hyperalgesia, de pen kin kam frɔm sɔmtin wae fɔ at, bɔt e kin tranga. Insay allodynia, di pen kin kɔmɔt frɔm sɔntin we nɔ fɔ at.

Aw dis tin we dɛn kɔl Hyperalgesia kin apin na wi bɔdi?

Hyperalgesia de chenj di we aw wi bɔdi de mek ɛn prosɛs di pen signal dɛm. Dis kin apin pan sɔm men we dɛn:

• di threshold fכ fil pen de dכn: Di pen threshold we sכmtin we dεn nכmal fכ fil se i nכ kɔmfyut kin bi pen de dכn bכku pan dis kכndyushכn. Dis min se ivin di smɔl tin kin mek pɔsin fil pen.
• di rispכns kin strכng bכku: di pen rεsεpכta dεm na wi bכdi kin bכku εn aktiv pas aw i nכmal. Dis kin mek di pen fil mɔ ɛn mɔ.
• di pen signal dεm nכ de stכp: Ivin afta dεn dכn pul di kכz fכ di pen, di pen risεptor dεm kin bi haypa sεnsitiv εn kכntinyu fכ sεnd pen signal to di bren.

Wi kin sheb dis to tu men kayn:

1. Primary hyperalgesia: Dis na we dɛn kin fil pen nɔmɔ na di say we di injury de. Fɔ ɛgzampul, di skin we di san dɔn bɔn kin fil mɔ pen na di say we di wund de.

2. Sɛkɔndari haypa aljɛsia: Dis na we dɛn kin fil pen na di say dɛn we de rawnd di injuri, we nɔ gɛt natin fɔ du wit di say we di injuri de. dis kin apin bikoz fכ di chenj na di we aw wi nεv sεstem de proכses di pen signal dεm.

Wetin na di kɔmɔn tin dɛm wae kin mek pɔrsin gɛt hyperalgesia?

wi no naw se dis kכndyushכn de kכz fכ di pen rεsεpכta dεm na wi bכdi de bi haypa sεnsitiv. Bɔku tin dɛn de we kin mek dis apin.

• Bɔn (inklud san bɔn) .
• Sting ɔ bit frɔm insɛkt, reptayl, ɔ ɔda animal
• Di tin dɛn we kin mek pɔsin gɛt kansa
• Di prɔblɛm dɛn we kin apin we pɔsin de yuz sɔm mɛrɛsin dɛn fɔ lɔng tɛm (wi go tɔk bɔt dis dɔŋ ya)
• Di nerve damej we pɔsin kin gɛt we i gɛt dayabitis (Diabetic Neuropathy) .
• Imyun sistεm sik dεm (e.g. Lupus, Multiple Sclerosis) .
• Infεkshכn dεm we de afekt di nεv sεstem (e.g. Shingles, Herpes virus) .
• Kɔndishɔn dɛn lɛk maygren
• Krכnik pen dizכrd dεm lεk `Kכmpleks rijyכnal pen sεndrכm`
• Ɛni kayn injuri we de na do (lɛk we di bon dɛn brok, di mɔsul dɛn we dɔn rɔtin, di nerve injury) .

Pen we de go ɔp bikɔs ɔf di mɛrɛsin dɛn we de mek pɔsin fil pen (Opioid-induced hyperalgesia - OIH) .

Dis na pɔynt we rili impɔtant ɛn we impɔtant fɔ pe atɛnshɔn to. We yu de yuz opioid pen kil (smɔl strɔng) fɔ lɔng tɛm, sɔmtɛm wan sayd ɛfɛkt we dɛn kɔl `Opioid-induced hyperalgesia (OIH)` kin apin. Dis min se di bɔdi in sɛnsitiviti to pen kin go ɔp bikɔs ɔf di pen kil we dɛn tek fɔ ridyus di pen, we kin mek di pen wɔs.

Dis na di rizin we mek dɔktɔ dɛn kin tink tu tɛm bɔt fɔ gi dɛn opioid pen kil fɔ lɔng tɛm. If pɔsin gɛt OIH, bɔku tɛm di dɔktɔ go ridyus di doz fɔ di mɛrɛsin smɔl smɔl ɛn afta dat i go stɔp am kpatakpata. Dis nɔ kin bi wan tɛm, bikɔs i kin mek pɔsin gɛt bad bad sayd ɛfɛkt. So, dɛn fɔ jɔs du dis ɔnda di advays ɛn sɔpɔt we dɔktɔ de gi.

Wetin na di tritmɛnt dɛm fɔ hyperalgesia?

Di tritmɛnt dipen pan di kɔz ɛn di kayn aypaaljɛsia. Dɛn kin yuz wan tritmɛnt ɔ wan tritmɛnt we dɛn kin yuz togɛda. Na yu dɔktɔ nɔmɔ go no us tritmɛnt bɛtɛ fɔ yu sik.

Na sɔm tritmɛnt dɛn we dɛn kin yuse:

• Mɛrɛsin: Dɛn kin yuz difrɛn kayn mɛrɛsin fɔ dis. Fɔ ɛgzampul, `Acetaminophen` (Paracetamol), `NSAIDs` (Nonsteroidal anti-inflammatory drugs), `Antidepressants`, sɔm mɛrɛsin fɔ ɛpilepsi, ɛn lokal anestetik lɛk `Lidocaine`.
• Nεv ablashכn: Dis kin min fכ disable fכ sכm tεm di nerv dεm we de sεnd di rכng pen signal dεm. Dɛn kin du dis bay we dɛn de yuz rediofrikyuɛnsi ablashɔn ɔ bay we dɛn injɛkt kemikal lɛk Bɔtɔks.
• Nεv blכk: We yu injεkt wan anεsthεtik drog insay di nerv fכ stכp di pen signal dεm fכ rich di bren.
• TƐNS (Transcutaneous electrical nerve stimulation): Na we fɔ kɔntrol di pen signal dɛn bay we dɛn de gi wan rili smɔl ilɛktrik kɔrɛnt tru di skin in safa.

Wetin na di bɛst tɛm fɔ go to dɔktɔ?

De pen wae kin kam wae yu kin fil smɔl, lɛk wae yu kin bɔn yu na di san, kin dɔn afta sɔm dez. Bɔt if di pen so bad dat yu nɔ go ebul fɔ bia ɛn mek i nɔ pɔsibul fɔ du di tin dɛn we yu de du ɛvride , ɔ if di pen kɔntinyu fɔ sɔm wiks , i go mɔs bi sayn fɔ se yu fɔ go to dɔktɔ.

I impɔtant mɔ fɔ go to dɔktɔ fɔ advays we yu bɔn bad bad wan (sɛkɔn digri ɔ pas dat), ɔ we yu bɔn na yu ed, yu fes, ɔ yu bɔdi. Yu dɔktɔ go advays yu bak if yu pen bad so dat yu go nid fɔ go na di Imejɛnsi Dipatmɛnt (ETU).

Pipul wae gɛt dis sik nɔr de mek lɛk se dɛn de fil pen ɔr de akt dɛn pen. Na bikɔs prɔblɛm de wit dɛn bɔdi in pen prɔses we de fil so tranga. So if yu ɔr pɔrsin wae yu sabi de gɛt dis kayn pen wae nɔr kɔmɔn, wae yu de fil bad bad wan, di bɛst ɛn sef tin fɔ du na fɔ go to dɔktɔ.