Yu gɛt blɔd bak na yu urine? Mek wi tok abaut IgA Nephropathy!

Yu dɔn ɛva notis smɔl blɔd na yu urine? Ɔ yu leg dɛn we swel, yu kin fil se yu wik, ɔ yu kin taya ɔltɛm? Dis kin bi sayn dɛm fɔ kidni sik, mi padi. Tide wi go tɔk bɔt wan sik we de na di kidni we gɛt sɔm kɔmplikɛt nem, bɔt we wi ɔl nid fɔ no bɔt. Na IgA Nɛfropati. Nɔ wɔri, lɛ wi tɔk bɔt am simpul wan.

Wetin na IgA Nɛfropati? Fɔ tɔk am simpul wan...

Fɔ tɔk am simpul wan, IgA nɛfrɔpati na wan kayn sik na di kidni. wetin de apin insay dis na dat wan `(Antibody)` na wi bכdi, dat na wan antibodi we dεn kכl `IgA`, de kכmכt insay di kidni dεm, we de mek inflameshn, dat na fכ swel. dis inflameshn de damej di sכm sכm bכdi vεsul dεm na di kidni dεm, di pat dεm we dεn kכl `(Glomeruli)` we de wok lεk filta. Imajin, wi kidni dɛn tan lɛk tu filta dɛn we de filta di dɔti tin dɛn we de na di bɔdi ɛn pul dɛn as urine. so, we dεn `(Glomeruli)` dεm dεn dכn pwεl, bכdi (`(Hematuria)`) εn protin (`(Proteinuria)`) de bigin kכmכt na di kidni dεm wit di urine.

Dɛn kin no am bak wit ɔda nem dɛm, lɛk `IgAN` ɛn `Berger's disease`. Di rizin fɔ dis na bikɔs tu Frɛnch dɔktɔ dɛm, Jean Berger ɛn Nicole Hinglas, bin fɔs fɛn dis sik insay di let 1960 dɛm.

Wetin dis nem min?

Di nem "IgA nephropathy" de saund likli long, no so? Lɛ wi si wetin i min.

• Immunoglobulin A (IgA): Dis na di antibodi we a bin dɔn tɔk bɔt. Na wan prɔtin we wi imyun sistɛm mek, di sistɛm we de protɛkt wi frɔm sik. Di men wok we i de du na fɔ protɛkt wi frɔm fɔrina dɛn we de kam insay wi lɛk baktri ɛn vayrɔs.
• Nɛfrɔpati: Dis na wɔd we dɛn kin yuz fɔ mɛn pipul dɛn. Fɔ tɔk am simpul wan, dɛn kin yuz am fɔ tɔk bɔt ɛni damej, sik, ɔ ɔda prɔblɛm we kin apin to di kidni.

Yu tink se dis de mek pɔsin in layf de pan denja?

Na dis na di impɔtant tin. If dɛn nɔ trit am, IgA nɛfrɔpati kin wɔs smɔl smɔl ɛn mek di kidni nɔ wok fayn. Kidni we nɔ de wok fayn kin mek pɔsin in layf de pan denja if dɛn nɔ trit am. Bɔt nɔr wɔri, if yu trit yu fayn fayn wan, yu kin kɔntrol aw dis sik de go bifo.

Aw dis sik kin bɔku?

IgA nefropathy na rili wan sik we kin rili kɔmɔn na di kidni. I kin afɛkt pipul dɛn we ol ɛni ej. Di we aw i bɔku kin difrɛn na difrɛn say dɛn na di wɔl. Dɛn ripɔt se dɛn kin si dis sik mɔ na di kɔntri dɛn na Ist Eshia, dat na di rijyɔn usay wi de. Dis sik na sɔntin bak we dɔktɔ dɛn kin si bɔku tɛm na Sri Lanka.

Wetin na di men sayn dɛm?

Bɔrku tɛm, nɔr kin gɛt ɛni sayn fɔs. Dis sik kin de fɔ lɔng lɔng tɛm ɔr ivin fɔ lɔng lɔng tɛm ɛn nɔr gɛt ɛni sayn. Bɔt we di sayn dɛn de sho, yu kin notis tin dɛn lɛk:

• Blɔd we de na di urine:Sɔntɛnde, di urine kin tɔn rɛd, brawn, ɔ di kɔlɔ we di ti wata gɛt. Dis na de fɔs sayn wae bɔrku pipul kin notis.
• Flank pen: Dis de tɔk bɔt pen na di tu say dɛn na di wɛst, usay di kidni dɛn de.
• Swɛlin (Edima): Swel kin apin, mɔ na di leg, anklɛ, bɛlɛ, ɛn sɔntɛnde na di fes.
• Fom urine: If i tan lɛk se yu urine de fom pas aw i fɔ bi, dat na sayn bak.

Imajin, Samantha (na lay lay nem) na yɔŋ ticha. Wan de, afta we i wɛl wit fiva, i notis se in urine de tɔn rɛd. I nɔ bin pe atɛnshɔn to am fɔs, i bin de tink se, "Sɔntɛm na jɔs taya." Bɔt afta sɔm dez, in leg dɛn bigin fɔ swel, ɛn i bin rili taya. Na afta we i go to dɔktɔ ɛn du tɛst, na in dɛn kam fɔ no se i gɛt IgA nɛfrɔpati.

Wetin mek dis sik kin apin? Wetin na di tin dɛn we kin mek i apin?

di mεdikal masta sabi pipul dεm biliv se IgA nεfropathy na ``autoimmune disease.`` Simpul wan, wetin de apin ya na dat wi כwn imyun sistεm, di sojaman dεm we dεn fכ protεkt wi frכm sik, de mistek atak wi כwn kidni dεm.

Pipul dεm we gεt IgA nεfropati gεt sכm kayn shuga we dεn kכl `(Galactose)` insay dεn `IgA` antibodi dεm pas nכmal. wi imyun sistεm de no dis `(Galactose)`-dεficient `IgA` as "fכrin invayda". Dɔn dis kin apin:

• כda antibodi dεm na wi bכdi de biεn dis `(Galactose)`-dεficient `IgA`.
• dis `IgA` de kam togεda fכ fכm sכm sכm kכlכm dεm we dεn kכl `Immune complexes`.
• dis ``Immune complexes'' kin stכk insay di sכm sכm filta dεm na wi kidni dεm, we dεn kכl ``Glomeruli''.
• Dɔn inflamɛns kin apin de ɛn di kidni dɛn kin bigin fɔ pwɛl.

we wi gεt kol, flu, כ trot we de at, dεn `IgA imyun kכmpleks dεm ya de sכkכt insay wi bכdi bכku bכku wan. Sɔm pan dɛn kin dɔn na di kidni, so sɔm pipul dɛn kin jɔs bigin fɔ gɛt di sayn dɛm fɔ IgA nɛfrɔpati afta dɛn dɔn gɛt kol ɔ flu.

Dis na sɔntin we kɔmɔt frɔm jɛnɛreshɔn?

Fɔ sɔm pipul dɛm, dis kin gɛt fɔ du wit di famili histri bɔt dis sik. Dat min se, i kin bi se wan jɛnɛtik inflɔwɛns de we de rɔn na famili dɛn. Dɔktɔ dɛn dɔn fɛn sɔm tin dɛn we kin mek pɔsin gɛt jɛnɛtiks. dat min se, i kin bi se wan link de bitwin sכm jin mכtεshכn dεm εn IgA nεfropati.

Udat dɛn kin gɛt dis sik pas ɔlman?

Pan ɔl we ɛnibɔdi kin gɛt IgA nɛfrɔpati, sɔm pipul dɛn kin gɛt mɔ risk. Dɛn tin ya na:

• If pɔsin na di famili gɛt IgA nɛfropati.
• If sɔmbɔdi na yu famili gɛt `IgA vasculitis` (dɛn kin kɔl am bak `(Henoch-Schönlein purpura)`).
• Sɔv we dɛn dɔn du na Amɛrika sho se man dɛn kin gɛt prɔblɛm tu tɛm pas uman dɛn.
• Fɔ yɔŋ pipul dɛn we ol bitwin 15-18 ia ɛn dɛn let 30 ia .
• Eshian ɔ YuropianDɛn se pipul dɛn we kɔmɔt na Eshia, lɛk Sri Lanka, kin si dis smɔl mɔ.

Us ej dis kin bigin?

Pan ɔl we dis sik kin afɛkt pipul dɛn we gɛt ɛni ej, di fɔs sayn dɛn kin bigin fɔ sho am we pɔsin yɔŋ, bitwin 15-18 ia ɛn let 30 ia.

Us prɔblɛm dɛn kin apin if dɛn nɔ trit am?

If dɛn nɔ trit IgA nɛfrɔpati fayn, difrɛn kɔmplikɛshɔn dɛn kin kam as tɛm de go. Di men wan dɛn na:

• Haypatɛnshɔn: Dis min se yu blɔd prɛshɔn go go ɔp .
• Akyu kidni failure: Wan wan tɛm we di kidni nɔ de wok fayn.
• Krכnik kidni fεil: Na di kidni dεm we de wik sכmtεm as tεm de go .
• Nεfrotik sεndrכm: Dis na kכndyushכn we di kidni dεm de kכl bכku bכku protin na di urine. Dis kin mek yu swel ɛn gɛt bɔku kɔlɔstrel.
• Prɔblɛm fɔ di at ɛn di blɔd sistɛm: Dis min se di risk fɔ gɛt at sik ɛn prɔblɛm wit di blɔd vesel kin bɔku.

Aw dɔktɔ dɛn kin no dis sik kɔrɛkt wan?

We yu go to dɔktɔ, i go aks yu bɔt yu sik, if ɛnibɔdi na yu famili dɔn gɛt dis sik, ɛn yu mɛdikal histri. Dɔn dɛn go du ɛgzam fɔ yu bɔdi, we kin min fɔ chɛk yu blɔd prɛshɔn ɛn chɛk fɔ si if yu swel. Apat frɔm dat, dɛn kin du dɛn tɛst ya:

• Urinalysis: I de chɛk fɔ blɔd ɛn protin na di urine.
• Blɔd tɛst: Chɛk di lɛvɛl we di kɔlɔstrel, prɔtin, ɛn dɔti we de na di blɔd gɛt.
• εstimat glomerular filtration rate (eGFR) bכdi tεst: Dis de mכsu כl di bכdi we yu kidni dεn de filta fayn fayn wan pan wan minit.
• Yurin protin tεst: I de chεk fכ protin εn/כ wan kayn protin we dεn kכl albumin insay di urine.
• 24 awa urine kolεkshכn tεst dεm: Kכlekt urine כl di de εn si aw bכku protin de kכmכt.

Yu tink se i nid fɔ tek di kidni bayɔpsi?

Yɛs, if ɔda tɛst dɛn mek pipul dɛn sɔprayz bɔt dis sik, di tɛst we impɔtant pas ɔl fɔ no if pɔsin gɛt di sik na fɔ tek di kidni bayɔpsi . Insay dis, dɔktɔ kin tek wan rili smɔl tisu na di kidni bay we i de yuz wan smɔl tin we tan lɛk nidul. Dɔn wan dɔktɔ we de stɔdi bɔt sik dɛn, we na spɛshal pɔsin we de chɛk di tisu dɛn, kin luk da pat de ɔnda maykroskɔp. Dɔn, dɛn kin tɔk klia wan if IgA de na di kidni, aw bɔku damej dɔn apin, ɛn us stej di sik de.

Wetin na di tritmɛnt dɛn we dɛn kin gɛt?

Di men gol fɔ tritmɛnt na fɔ kɔntrol aw di sik de go bifo ɛn mek i nɔ go bifo to ɛnd-stej rεnal sik (ESRD). If dɔktɔ tɛl yu se yu gɛt IgA nɛfrɔpati, i go mɔs bi se dɛn go sɛn yu to nɛfrɔlɔg, dɔktɔ we spɛshal pan kidni sik.

Di tritmɛnt fɔ IgA nɛfropati kin inklud dɛn mɛrɛsin ya:

• kכntrol bכdi prεshכn: mεdikeshכn dεm lεk `(Angiotensin-kכnvεrt εnzym - ACE) inhibito dεm` εn `(Angiotensin rεsεpכta blכk dεm - ARB dεm)`. Dɛn tin ya kin mek di blɔd prɛshɔn go dɔŋ ɛn i kin mek di kidni dɛn nɔ pwɛl bak.
• Rimov di wata we pasmak na di bɔdi: Diuretic medications, we dɛn kin kɔl "water pills."
• kכntrol di imyun sistεm: fכ ridyus di inflameshn na di kidni dεm, dεn kin gi כda mεdikeshכn dεm lεk stεroyd (e.g., prεdnison) כ sayklofosfamid. Dɛn kin gi dɛn tin ya dipen pan aw di sik tranga.
• di kכlestכl lεvεl dεm we lכs: Mεdikeshכn dεm lεk `(Statins)`.

Fɔ pul di tonsil (Tonsillectomy) kin ɛp fɔ dis?

Sɔm risach dɔn sho se smɔl nɔmba pan pipul dɛm wae gɛt IgA nɛfrɔpati kin bɛnifit if dɛn tek tonsilɛkt. Bɔt dis nɔto tritmɛnt fɔ ɔlman . I bɛtɛ fɔ tɔk to yu dɔktɔ fɔ si if dis fayn fɔ yu.

Wetin yu fɔ ɛkspɛkt we yu de liv wit dis sik?

Dis kin difrɛn frɔm wan pɔsin to ɔda pɔsin. Sɔntɛnde IgA nɛfrɔpati kin bɛtɛ wit simpul tritmɛnt. Na smɔl tɛm nɔmɔ, di sik kin wɔs kwik kwik wan, ɛn dis kin mek di kidni nɔ wok fayn insay sɔm ia.

Bɔt if dɛn tek di rayt tritmɛnt, bɔku pipul dɛn kin liv wit dɛn kidni dɛn we gɛt wɛlbɔdi ɛn kɔntrol aw di sik de go bifo.

Stɔdi dɔn sho se lɛk wan pan ɛvri 4 big pipul dɛn we gɛt IgA nɛfrɔpati kin gɛt prɔblɛm wit dɛn kidni as tɛm de go. pan pikin dεm, dis risk kin bכku lεk wan pan 10 to 20 pikin dεm.

Yu tink se i go nid fɔ transplant di kidni?

I kin difrɛn bak frɔm wan pɔsin to ɔda pɔsin. Nɔto ɔlman in sik kin go bifo di sem rit. Sɔm pipul dɛn kin du wɛl pan tritmɛnt ɛn kin liv wit de sik fɔ lɔng tɛm.

If yu kidni dɛn stɔp fɔ wok wantɛm wantɛm bikɔs ɔf IgA nɛfrɔpati, yu kin nid fɔ tink bɔt dayalaysis (we na wan we fɔ klin blɔd) ɔ fɔ transplant kidni. Yu mɛdikal tim go tɔk to yu ɔl dɛn tin ya we yu go ebul fɔ du.

Aw lɔng dis sik kin te?

IgA nefropati na wan sik we de go bifo pan di kidni we kin te fɔ ɔl yu layf. Dis min se i kin wɔs as tɛm de go. Bɔt, mɛrɛsin kin mek di rit we di sik de go bifo kwik kwik wan.

Wetin wi go se bɔt di layf we pɔsin de liv?

Stɔdi dɔn sho se di avɛrej layf we pipul dɛn we gɛt IgA nɛfropati kin liv kin ridyus bay lɛk 6 to 10 ia we yu kɔmpia am wit pɔsin we nɔ gɛt dis sik. Bɔt, dis na jɔs wan statystik. Nɔr fɔgɛt se wit gud tritmɛnt ɛn chenj na yu layf, dɛn kin kɔntrol dis sik bɔku pan.

A go ebul fɔ liv nɔmal layf?

Fɔ tru, na yɛs! If dɛn trit dɛn fayn ɛn liv dɛn layf lɛk aw dɛn dɔktɔ se, bɔku pipul dɛn we gɛt IgA nɛfropati kin liv lɔng, gladi layf. Dɛn kin kɔntinyu fɔ wok, go skul, ɛn du di tin dɛn we dɛn lɛk.

Yu tink se we de fɔ mek dis nɔ apin?

כnכfכs, no prכvεnt we de fכ prεvεnt IgA nεfropati. Bɔt if pɔsin na yu famili gɛt dis sik, i impɔtant fɔ tɔk to yu dɔktɔ bɔt aw fɔ gɛt wɛlbɔdi, mɔ fɔ mek yu nɔ kɔntrol yu blɔd prɛshɔn ɛn kɔlɔstrel.

Fɔ it ɛn drink kin afɛkt dis?

Risach nɔ dɔn fɛn yet dairekt link bitwin di it we yu de it ɔ di it we yu de it ɛn fɔ mek i nɔ gɛt IgA nɛfrɔpati.

Us it ɛn drink dɛn we wi fɔ avɔyd?

Dɔktɔ kin tɛl pɔsin we gɛt IgA nɛfrɔpati fɔ stɔp sɔm it ɛn drink dɛn, lɛk:

• Fɔ ridyus di sɔl .
• Fɔ stɔp fɔ it tin dɛn we gɛt bɔku prɔtin (lɛk mit, fish, eg, ɛn milk).

If yu gɛt bɔku kɔlɔstrel, dɛn kin advays yu fɔ ridyus di sɛtyuret fat ɛn it dɛn we gɛt bɔku kɔlɔstrel.

Wetin mek yu se fɔ ridyus di prɔtin?

sכm pan di tin dεm we de mek we dεn digεst di protin nid fכ filta dεm bay di kidni dεm. So, if yu it bɔku tin dɛn we gɛt bɔku prɔtin, yu kidni dɛn fɔ wok tranga wan, we kin mek yu kidni dɛn wik kwik kwik wan. Bɔt if yu nɔ it bɛtɛ prɔtin, yu kin gɛt prɔblɛm dɛn lɛk we yu nɔ de it fayn. So, i bεst fכ go to rεnal dεytishכn fכ εp yu fכ mek wan it we rayt fכ yu εn we gud fכ yu kidni dεm. If dɛn dɔn advays yu fɔ ridyus di prɔtin we yu de it, yu go nid fɔ du blɔd tɛst ɔltɛm fɔ chɛk yu prɔtin lɛvɛl.

A fɔ tek Omega-3 pils?

Fɔ sɔm pipul dɛn we gɛt IgA nɛfrɔpati, dɔktɔ dɛn kin tɛl dɛn fɔ tek fish ɔyl we gɛt omega-3 fat asid. Sɔm stɔdi dɔn sho se dɛn tin ya kin mek di blɔd prɛshɔn go dɔŋ ɛn mek di sik nɔ go bifo kwik kwik wan.

Bɔt i rili impɔtant fɔ mek yu nɔ ɛva bigin fɔ tek ɛni sɔpɔtmɛnt, ivin fish ɔyl pils, we yu nɔ go to dɔktɔ.

Ustɛm a fɔ go to dɔktɔ?

Fɔ mek yu gɛt wɛlbɔdi, i go fayn fɔ mek yu go to dɔktɔ ɔltɛm ɛn mek dɛn chɛk yu fɔ mɛn yu, jɔs lɛk ɔlman.If yu no am kwik kwik wan, i kin ɛp fɔ mek di IgA nɛfrɔpati nɔ go bifo te i nɔ ebul fɔ du di kidni. Dɔn bak, if yu gɛt ɔda tin dɛn we kin afɛkt yu kidni, lɛk ay blɔd prɛshɔn ɔ dayabitis, i impɔtant fɔ wok wit yu dɔktɔ fɔ mɛn dɛn fayn fayn wan.

Ustɛm yu fɔ go na Imejɛnsi Tritmɛnt Yunit (ETU) ?

If yu gɛt IgA nɛfrɔpati ɛn yu gɛt sayn dɛn we de sho se yu kidni nɔ de wok fayn, yu fɔ go na di imejensi rum we de nia yu wantɛm wantɛm. Dɛn kayn sayn ya na:

• Fɔ fil taya pas aw yu kin fil na ``Fatigue''.
• Di frɛkuɛns ɔ di amɔnt we pɔsin kin pis kin go ɔp ɔ dɔŋ pas aw dɛn bin de tink.
• Di it nɔ de te.
• Nɔ slip ɔ i nɔ kin izi fɔ pe atɛnshɔn pan sɔntin.

Wetin na di impɔtant kwɛstyɔn dɛn we wi fɔ aks di dɔktɔ?

We yu lan bɔt dis sik, yu kin gɛt bɔku kwɛstyɔn dɛn. I impɔtant fɔ aks yu dɔktɔ ɛn mek dɛn no klia wan. Na sɔm kwɛstyɔn dɛn we yu kin aks:

• Aw yu kin no di kɔrɛkt we aw yu gɛt IgA nɛfrɔpati?
• Wetin na di bɛst tritmɛnt fɔ mi?
• Wetin na di sayd ɛfɛkt dɛm fɔ di tritmɛnt dɛm we yu kin advays?
• We dɛn pul mi tɔnsil dɛn, dat go ɛp mi?
• A fɔ go to pɔsin we de mɛn di rεnal diet?
• I fayn fɔ mek a tek fish ɔyl sɔpɔtmɛnt?
• Aw ɔltɛm a fɔ du blɔd ɛn urine tɛst?
• A go nid fɔ transplant mi kidni?
• Ɛni klinik trial de we go fayn fɔ mi?
• Yu kin tɛl mi bɔt sɔpɔt grup fɔ pipul dɛn we gɛt IgA nɛfrɔpati?

We yu no se yu gɛt sik na yu kidni, dat kin mek yu sɔprayz. Bɔku infɔmeshɔn de kam na yu maynd wan tɛm, tɛst dɛn we dɛn fɔ du, apɔntinmɛnt fɔ si spɛshal pipul dɛn... Na nɔmal tin fɔ fil se yu dɔn ful-ɔp wit ɔl dat. Di tin we impɔtant pas ɔl na fɔ tek briz ɛn rili ɔndastand wetin na IgA nɛfrɔpati.

Fɔ sɔm pipul dɛm, dis nɔr so siriɔs, ɛn simpul tritmɛnt ɛn tɛst ɔltɛm kin ɛp fɔ mek dɛn kidni kɔntinyu fɔ wok. Fɔ ɔda pipul dɛn, dɛn nid mɛrɛsin fɔ protɛkt di kidni dɛn. Bɔt mɛmba se yu kin ebul fɔ mɛn dis sik, ɛn if yu trit yu fayn, yu go ebul fɔ liv fayn fɔ lɔng tɛm.

Gɛt ɛp frɔm yu famili ɛn padi dɛn. Sɔpɔt grup fɔ pipul dɛm wae gɛt dis kayn sik kin bi bak fayn ples fɔ tɛl yu bɔt aw yu de tink. No hesitate fo aks dokta if yu geht eni kweshon, mi padi.

Faynal Mɛsej fɔ Tek-Hom

Okay, so wi don tok plenti boht IgA nephropathy, no so? Fɔ dɔn, na di impɔtant tin dɛn we yu fɔ mɛmba:

• Fɔ no am kwik kwik wan rili impɔtant: so, if yu gɛt sɔm sayn dɛn lɛk blɔd na yu urine ɔ yu de swel, mek shɔ se yu go to dɔktɔ.
• Fɔ fala di tritmɛnt instrɔkshɔn dɛn fayn fayn wan: Tek di mɛrɛsin we di dɔktɔ tɛl yu fɔ tek di mɛrɛsin di rayt tɛm. Fɔ fala di instrɔkshɔn dɛn.
• Di chenj dɛn we yu fɔ du na yu layf: Du wetin yu dɔktɔ tɛl yu bɔt aw fɔ it ɛn ɛksesaiz. If dɛn tɛl yu fɔ kɔntrol di sɔl ɛn prɔtin we yu de it, du dat.
• Chek-ap ɔltɛm wit dɔktɔ: Tek tɛm chɛk-ap ɔltɛm lɛk aw yu dɔktɔ tɛl yu ɛn kip yu yay pan di kɔndishɔn na yu kidni.
• Dis na sik we pɔsin kin ebul fɔ kɔntrol: Nɔ wɔri. If yu gɛt di rayt tritmɛnt ɛn wɛl bɔdi layf, yu kin liv gladi ɛn wɛl bɔdi layf wit IgA nɛfrɔpati.
• Nɔto yu wan de: yu gɛt fambul dɛn, padi dɛn, ɛn dɔktɔ dɛn fɔ ɛp yu. Yu kin gɛt bɔku trɛnk bak na sɔpɔt grup dɛn.

Tek kia ɔf yu kidni wɛlbɔdi, padi!

` IgA Nεfropati, IgA Nεfropati, Kidni Sik, Buerger in Sik, Blɔd insay Yurin, Proteinuria, Kidni Failure, Kidni Bayopsi, Kidni Transplant