Yu dɔn ɛva wɔnda aw wi bɔdi kin fɛt ɛnimi lɛk vayrɔs we i kam insay wi bɔdi? Wi bɔdi gɛt wan wɔndaful difens sistɛm. wan pan di imכtant ‘sayn ejen dεm’ na da sistεm de dεn kכl am intafεron. Dis na rili prɔtin dɛn we wi bɔdi de mek insɛf. Dɔn bak, dɛn kin gi intafɛron we dɛn mek wit atifishin as drɔg as tritmɛnt fɔ sɔm mɛrɛsin dɛn. Lɛ wi tɔk bɔt dis simpul we tide.
Fɔ tɔk am simpul wan, wetin na intafɛron?
Imajin se wi bɔdi na big siti. Wan ami we dɛn kɔl di imyun sistɛm de protɛkt dis siti. Naw wan ɛnimi, lɛk vayrɔs ɔ kansa sɛl, de kam insay dis siti. na da tεm de, di sεl dεm (fכ egzampl, wayt blכd sεl dεm) we de na di εria we dis εnimi de, de mek wan wכning signal. di protin we de gi da signal de dεn kכl am intafεron.
Dis nem rili intrestin. dis dεm de "intafεr" wit jεm lεk vayrus frכm fכ mכltiply insay di bכdi, dat na frכm fכ bi infεkshכn. na dat mek dεn kכl dεm 'intafεrons'.
So, pan ɔl we dɛn kin mek dɛn tin ya na wi bɔdi na wi bɔdi, na sayɛnsman dɛn we de na lɛbɔretri kin mek dɛn bak wit atifishin ɛn dɛn kin yuz dɛn as tritmɛnt fɔ difrɛn sik dɛn. Dɛn bin fɔs mek intafɛron dis we insay 1986 fɔ trit sɔm kayn kansa.
Aw intafɛron de wok?
di intafεron dεm lεk di fכs layn fכ difεns na wi bכdi in difεns sistεm. We wan sɛl gɛt vayrɔs, da sɛl de kin mek intafɛron ɛn sɛn wɔnin to di wɛlbɔdi sɛl dɛn we de rawnd am. As if yu de se, "Na enimi de kam, aktiv yu difens dem tu!"
we dεn gεt dis signal, כda sεl dεm dεn tu de pripia fכ fכt di vayrus. intafεron de kכl כda fכt dεm bak na wi imyun sistεm (lεk כda kayn protin we dεn kכl saytokin) fכ jɔyn di fכt.
Dis na di sem tin we kin apin wit intafɛron we dɛn kin gi wit atifishal wan.
- i de tεl di imyun sistεm fכ "dεstroy dεn sεl dεm ya."
- I de stɔp di kansa sɛl ɛn vayrɔs dɛn fɔ sheb ɛn skata.
- I de ɛp di sɛl dɛn we gɛt wɛlbɔdi fɔ fɛt infɛkshɔn.
Tri men kayn intafɛron dɛn de.
- Intɛrfɛrɔn-alfa
- Intɛrfɛrɔn-beta
- Intɛrfɛrɔn-gama
Us sik dɛn kin trit wit intafɛron as mɛrɛsin?
difrεn kayn intafεron dεm dεn kin yus fכ trit difrεn kכndyushכn dεm. Si di tebul we de dɔŋ fɔ ɛksplen we izi fɔ ɔndastand.
| Tayp fɔ intafɛron | Di kɔndishɔn dɛn we dɛn de trit |
|---|---|
| Intɛrfɛrɔn-alfa |
|
| Intɛrfɛrɔn-beta | Fɔ difrɛn kayn ɔtoimyun sik we dɛn kɔl Multiple Sclerosis (MS). dis de εp fכ ridyus di inflameshn na di nεv dεm na di bren εn di spεnal kכd. |
| Intɛrfɛrɔn-gama |
|
Aw dɛn kin gi dis tritmɛnt?
Yu dɔktɔ go gi yu dis mɛrɛsin as injɛkshɔn ɔnda di skin ɔ insay wan mɔsul . Sɔntɛnde dɛn kin gi am bak as infushɔn insay wan vein na yu an. Dɛn kin gi dis tritmɛnt na ɔspitul ɔ klinik. Bɔt sɔntɛnde, yu dɔktɔ ɔ nɔs go tich yu aw fɔ gi yusɛf di injɛkshɔn na os.
Di kayn mɛrɛsin we dɛn go gi yu, di doz we dɛn go gi am, ɛn aw lɔng dɛn go gi am, go dipen pan di sik we yu gɛt.
Wetin na di sayd ɛfɛkt ɛn risk dɛm fɔ intafɛron tritmɛnt?
Lɛk ɛni pawaful mɛrɛsin, intafɛron tɛrapi kin gɛt sayd ɛfɛkt ɛn kɔmplikeshɔn. Bɔt mɛmba se yu dɔktɔ de tɛl yu fɔ du dis tritmɛnt bikɔs di bɛnifit dɛn pas di bad tin dɛn we kin apin to yu.
Nɔ fred fɔ tɔk opin wan bɔt ɛni wan pan dɛn sayd ɛfɛkt ya wit yu dɔktɔ so dat i go tek di step dɛn we i nid.
| Kɔmɔn sayd ɛfɛkt ɛn kin gɛt siriɔs kɔmplikeshɔn | |
|---|---|
| Kɔmɔn sayd ɛfɛkt dɛm wae bɔrku pipul kin gɛt | |
| Simptom dɛm we tan lɛk flu | Sɔm kayn sik lɛk fiva, kol, bɔdi we de at, ed we de at, ɛn nɔys kin apin sɔm awa afta yu tek di mɛrɛsin. Bɔku tɛm, dɛn tin ya kin stɔp insay 24 awa. |
| Ɔda sayd ɛfɛkt dɛn | Skin rash, taya pasmak, ia kin lɔs (alopecia), nɔ kin want fɔ it, ɛn i nɔ kin ebul fɔ tinap tranga wan pan man dɛn kin apin. |
| Pɔtɛnɛshɛl siriɔs kɔmplikeshɔn dɛm wae nid spɛshal atɛnshɔn | |
| Prɔblɛm dɛn we gɛt fɔ du wit at | Sɔm pipul dɛn kin gɛt lɔw blɔd prɛshɔn, dɛn at nɔ kin bit ɔltɛm ɔ dɛn kin bit kwik kwik wan. Yu dɔktɔ go wɔri mɔ if yu gɛt at sik. |
| Prɔblɛm dɛn we gɛt fɔ du wit wɛlbɔdi biznɛs | Sɔm pipul dɛn kin gɛt pwɛl hat ɔ dɛn kin tink bad bɔt layf. If yu dɔn gɛt prɔblɛm wit yu maynd, yu dɔktɔ go wach yu gud gud wan we yu de du dis tritmɛnt. |
| Prɔblɛm dɛn we gɛt fɔ du wit di yay | If yu gɛt tin dɛn lɛk dayabitik retinopathy, dis mɛrɛsin kin mek dɛn wɔs. So, yu dɔktɔ go tɛl yu fɔ chɛk yu yay bifo ɛn we dɛn de du tritmɛnt. |
| Tayrɔyd prɔblɛm dɛn | Sɔm pipul dɛn kin gɛt tin dɛn lɛk we dɛn gɛt tayroyd gland we de wok pasmak (haypa tayroyd) ɔ we dɛn gɛt tayroyd gland we nɔ de wok fayn (haypotayroydism). |
| Prɔblɛm dɛn we kin apin na di lɔng | If yu gɛt lɔng sik lɛk brɔnkayt ɔ nyumonia, dis mɛrɛsin kin mek dɛn wɔs. |
Mɛsej we dɛn kin kɛr go na os
- Intafɛron na natura l difεns mεkanism na wi bכdi we de fכt jεm εn kansa sεl dεm.
- Intafɛron, we dɛn kin mek na lɛbɔraytri, na pawaful tritmɛnt fɔ siriɔs sik dɛn lɛk epataytis, maltipul sklɛrosis (MS), ɛn sɔm kansa dɛn.
- Dis tritmɛnt kin mek yu gɛt sayd ɛfɛkt, lɛk fiva. Smɔl risk de bak fɔ gɛt siriɔs prɔblɛm dɛn. I impɔtant fɔ no bɔt dis.
- Fil fri fɔ tɔk to yu dɔktɔ bɔt ɛni prɔblɛm ɔ sayd ɛfɛkt we yu go gɛt.
- Nɔ ɛva chenj di doz ɔ stɔp fɔ tek yu mɛrɛsin if yu nɔ gɛt dɔktɔ advays. Yu dɔktɔ dɔn pik dis tritmɛnt fɔ yu yon wɛlbɔdi.
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