Sɔntɛnde, yu kin fil bad bad wan, wɔri, ɔ yu kin jɔs bost wit layf? Insay mɛrɛsin, wi kin kɔl dis kɔndishɔn ``Dipreshɔn``. So, dɔktɔ dɛn kin gi wi sɔm mɛrɛsin dɛn fɔ ɛp wi insay tɛm lɛk dis. fכ egzampl, wan spεshal mεdikeshכn we dεn kin yus fכ trit wan kכndyushכn we dεn kכl diprεshכn na ``Isocarboxazid``. ``Marplan`` na ɔda brand nem fɔ dis mɛrɛsin.
Us kayn mɛrɛsin na `Isocarboxazid`?
Fɔ tɔk am simpul wan, `Isocarboxazid` na mɛrɛsin wae de ɛp fɔ ridyus yu sɔri, wɔri ɛn impɔtant yu mud. wi bren gεt kεmikכl mεsenja dεm we dεn kכl `Dopamine`, `Norepinephrine` εn `Serotonin`. Dis na di kemikal dɛm wae de ɛp fɔ kɔntrol wi filin fɔ gladi ɛn pwɛl hat. `Isocarboxazid` de wok bay we i de inkrεs di lεvεl dεm fכ dεn kεmikכl dεm ya na di bren.
Dis mɛrɛsin de pan di grup we dɛn kɔl `MAOI`. `MAOI` tinap fɔ `Monoamine Ɔksidayz Inhibitɔ dɛn`. dis εnzym (`Monoamine Oxidase`) de brok dכn di kεmikכl dεm we wi bin dכn tכk bכt lεk `Dopamine`, `Norepinephrine`, `Serotonin` na wi bכdi. so, biכs `MAOI` mεdisin de stכp di aktiviti fכ da εnzym de, dεn gud kεmikכl dεm de de na di bren fכ lכng tεm. Na dat kin ɛp fɔ ridyus pwɛl hat. Bɔt dɔktɔ dɛn kin gi dis mɛrɛsin bak fɔ ɔda sik dɛn. So if yu gɛt ɛni kwɛstyɔn, aks yu dɔktɔ ɔ fama.
Tin dɛm wae yu fɔ tɛl yu dɔktɔ bifo yu bigin dis mɛrɛsin
Bifo yu bigin fɔ tek `Isocarboxazid`, sɔm tin dɛn de we yu fɔ rili tɛl yu dɔktɔ. Na bikɔs dis mɛrɛsin nɔ fayn fɔ ɔlman. So, yu fɔ tɛl yu dɔktɔ bɔt dɛn tin ya rili ɔnɛs wan.
- Yu gɛt di ay sik `Glaucoma`?
- Yu kin gɛt ed pen ɔ maygren ɔltɛm?
- Yu gɛt at sik?
- Yu gɛt ay blɔd prɛshɔn?
- Yu dɔn gɛt at bit we nɔ de bit ɔltɛm?
- Yu dɔn gɛt strok bifo?
- Yu na pɔsin we de drink ɔltɛm?
- Yu gɛt sik na yu kidni?
- Yu gɛt liva sik?
- Ɛni ɔda sik dɛn de we pɔsin kin gɛt na in maynd?
- wan kεnsar kכndyushכn de na di adrenal gland we dεn kכl `Pheochromocytoma`?
- Yu dɔn gɛt injuri na yu ed i nɔ tu te yet (ed trauma)?
- Ɛni sik de we kin mek pɔsin sik?
- Yu dɔn tink bɔt fɔ kil yusɛf, plan fɔ kil yusɛf, ɔ tray fɔ kil yusɛf bifo? Ɛnibɔdi na yu famili dɔn ɛva du dat?
- Yu gɛt alɛji fɔ di mɛrɛsin `Isocarboxazid`, ɔda mɛrɛsin, it, day, ɔ prɛzɛvɛtiv?
- Yu gɛt bɛlɛ ɔ yu de tray fɔ gɛt bɛlɛ?
- Yu na mama we de gi pikin in bɛlɛ?
If ɛni wan pan dɛn tin ya apin to yu, i rili impɔtant fɔ tɛl yu dɔktɔ bɔt am.
Aw a fɔ yuz dis mɛrɛsin?
Dis mɛrɛsin kin kam lɛk tablɛt. Yu fɔ tek am wit yu mɔt wit wan glas wata. I bɛtɛ fɔ tek am lɛk aw yu dɔktɔ tɛl yu fɔ tek am, di sem tɛm ɛvride. Kɔntinyu fɔ tek dis mɛrɛsin te yu dɔktɔ tɛl yu fɔ stɔp.
We di famasi gi yu dis mɛrɛsin, i kin gi yu spɛshal instrɔkshɔn liflet bak (wan `MedGuide`). Yu fɔ rid dis `MedGuide` fayn fayn wan ɛvri tɛm we yu de tek di mɛrɛsin ɛn we yu chenj di mɛrɛsin bɔtul. I gɛt rili impɔtant tin dɛn bɔt dis mɛrɛsin.
Mɛmba se: Dis mɛrɛsin na fɔ yu nɔmɔ. Nɔ sheb yu mɛrɛsin wit ɔda pipul dɛn, ilɛksɛf dɛn gɛt di sem sayn lɛk yu.
If yu de gi dis mɛrɛsin to yɔŋ pikin dɛn, yu fɔ tek tɛm spɛshal. So, tɔk to yu dɔktɔ bɔt am ɛn gɛt advays.
If yu tink se yu dɔn tek dis mɛrɛsin tumɔs, go na di ɔspitul imejensi dipatmɛnt we de nia yu wantɛm wantɛm, ɔ kɔl pɔyzin kɔntrol sɛnta, ɛn nɔ de te.
Wetin fɔ du if yu mis wan doz fɔ mɛrɛsin?
If yu fɔgɛt fɔ tek wan doz, tek am jɔs lɛk aw yu mɛmba. Bɔt if i dɔn lɛf smɔl fɔ lɛ yu tek yu nɛks doz, skip di doz we yu mis ɛn tek yu nɛks doz di tɛm we yu dɔn sɛtul. Nɔ ɛva tek tu dos wan tɛm. If yu du dat, dat kin mek di doz go ɔp.
Ɔda tin dɛm wae kin intarakt wit dis mɛrɛsin (intarakshɔn dɛm) .
Dis na sɔntin we wi fɔ rili tek tɛm wit . Di drɔg `Isocarboxazid` kin intarakt bad bad wan wit sɔm it ɛn ɔda mɛrɛsin dɛm. Dis kin mek yu gɛt bad bad sayd ɛfɛkt.
Nɔ it it dɛn we gɛt `Tyramine`!
I nɔ fayn fɔ it it dɛn we gɛt bɔku kemikal tyramine we yu de tek `Isocarboxazid`. if dεn tu tin ya kam togεda, kכndyushכn dεm we de mek yu layf de pan denja lεk ed we de at bad bad wan, hεy blכd prεshכn (`Hypertensive crisis`), כ at bit we nכ de bit kin apin.
Us it dɛn we gɛt bɔku `Tyramine`?
- Chiz dɛn we dɔn ol
- Mit we dɛn dɔn prosɛs - tin dɛn lɛk sosish, salami, pepperoni
- Bia ɛn ale (ivin bia we nɔ gɛt rɔm) .
- Wayn (especially red wayn), sheri
- Hard liquor, Likɔr dɛn
- Avokado we dɛn kɔl
- Banana (especially di wan dɛn we dɔn rayp fayn) .
- Fig, Resin dɛn
- Soya sos, Miso sup
- Yist/protɛin ɛkstrakt dɛn
- Tofu (Bin kɔd) .
- Fava ɔ brayt bin pɔd dɛn
- Ɛni frut we dɔn rayp pasmak
Dis list nɔ kɔmplit, so aks yu dɔktɔ, fama, ɔ pɔsin we sabi bɔt it fɔ wan kɔmplit list fɔ di it dɛn we gɛt tayramin.
Dɔn bak, i fayn fɔ lɛ yu nɔ drink bɔku tin dɛn we gɛt kafinɛ (lɛk ti, kɔfi, chɔklɛt, ɛn kola) we yu de tek dis mɛrɛsin.
Aks yu dɔktɔ aw lɔng yu fɔ avɔyd dɛn it ɛn drink ya afta yu dɔn stɔp dis mɛrɛsin.
Mɛrɛsin wae nɔr fɔ ɛva tek wit dis mɛrɛsin
di mεdikeshכn dεm we de kam biεn kin mek yu gεt rili siriכs riakshכn if dεn tek dεm tכgeda wit `Isocarboxazid`. So, if yu de tek dɛn mɛrɛsin ya naw, yu fɔ tɛl yu dɔktɔ.
- Atomoxetin we dɛn kɔl
- `Buspirone`
- `Karbamazɛpin`
- Sɔm mɛrɛsin dɛn we gɛt ay blɔd prɛshɔn: `Guanabenz`, `Guanadrel`, `Guanethidine`, `Reserpine`
- `Kɔkɛyn`
- `Sayklɔbɛnzaprin`
- Dextromethorphan (we gɛt sɔm kɔf srɔp dɛn) .
- Drug ɔ tin dɛn we de mek pɔsin nɔ gɛt bɔku bɔku bɔdi: Amphetamines, Ephedra
- `Difenoksilet`
- `Ɛfɛdrin`
- Jɛnɛral ɔ lokal anestetik (if yu de tek dɛn mɛrɛsin ya bifo yu du di ɔpreshɔn, yu fɔ tɛl yu dɔktɔ ) .
- `Ginseng`
- Grin ti (we yu de it pasmak) .
- `Guarana`
- Linezolid (wan antibayɔtik) .
- Ɔda kayn `MAOI`: `Fɛnɛlzin` (fenɛlzin), `Rasagilin` (rasagilin), `Safinamid` (safinamid), `Selegilin` (sɛlɛjilin), `Tranilsaypromin` (tranilsaypromin)
- Mɛrɛsin fɔ maygren ed we de at
- Mεdisin dεm fכ muvmεnt dizayd lεk Pakinsin sik: `Entacapone`, `Levodopa`, `Selegiline`, `Tolcapone`
- Meperidine (we de mek pɔsin nɔ fil pen) .
- `Methylene blu`
- Mɛrɛsin fɔ ɔda pwɛl hat, wɔri, ɔr prɔblɛm wit aw pɔrsin de fil
- Di mɛrɛsin dɛn we dɛn kin gi pɔsin we de mek pɔsin fil pen
- `Prokarbazin`
- `SAM-e`
- `St. John’s Wort` (na ɛbul mɛrɛsin we sɔm pipul dɛn kin tek fɔ mek dɛn gɛt wɛlbɔdi)
- `Tramadol` (dɛn mɛrɛsin we de mek pɔsin fil pen) .
- `Triptofan`
- Tyramine (dɛn kin de na it ɛn dɛn kin de bak na sɔm supamakit dɛn) .
- `Vilɔksazin`
- `Yohimbine`
Ɔda mɛrɛsin dɛm wae kin miks wit dis mɛrɛsin
di mεdikeshכn dεm we de kam biεn kin intarakt bak wit `Isocarboxazid`. So, if yu de tek dɛn tin ya, tɛl yu dɔktɔ bɔt dɛn bak.
- Barbiturates (e.g. Fɛnobarbital) .
- Diuretiks we dɛn kin yuz fɔ pul wata
- Isoniazid (na mɛrɛsin fɔ TB) .
- Mɛrɛsin fɔ di sayn dɛm lɛk kol, alɛji, ɛn flu
- Mɛrɛsin fɔ gɛt dayabitis
- Mεdisin dεm we de na di `Fεnotiazin` grup (e.g. `Klɔrpromazin`, `Proklɔrpɛrazin`, `Thioridazin`)
Dis list nɔ kɔmplit. So tɛl yu dɔktɔ bɔt ɔl di mɛrɛsin dɛn we yu de tek (we dɛn gi yu, we yu nɔ de bay, ɛbul, vaytamɛn, nyutrishɔn sɔpɔtmɛnt). Tɛl yu dɔktɔ bak if yu de smok, drink rɔm, ɔ yuz ɔda drɔgs. Sɔm tin kin miks wit dis mɛrɛsin.
Ɔda tin dɛn we yu fɔ tek tɛm wit we yu de tek dis mɛrɛsin
- If yu sik nɔr de bɛtɛ ɔr i tan lɛk se yu de wɔs, tɛl yu dɔktɔ wantɛm wantɛm. Kɔntinyu fɔ tɔk to yu dɔktɔ fɔ si aw di mɛrɛsin de wok. I kin tek sɔm wiks fɔ mek dis mɛrɛsin bigin fɔ wok. So, e fayn fɔ kɔntinyu fɔ tek di tritmɛnt lɛk aw yu dɔktɔ tɛl yu.
- Fɔ tink bɔt fɔ kil yusɛf ɔ fɔ mek yu at pwɛl mɔ ɛn mɔ: Dis rili impɔtant . Wae yu de tek dis mɛrɛsin, mɔr lɛk wae yu bigin fɔ trit yu ɔr afta yu dɔn chenj di doz, wach yu maynd fayn fayn wan fɔ no nyu tin wae yu de tink bɔt fɔ kil yusɛf ɔr pwɛl hat sik wae de wɔs. Dɔn bak, if yu gɛt ɛni chenj wantɛm wantɛm na yu maynd, lɛk fɔ fil wɔri, nɔ de rɛst, fɔ vɛks, fɔ et yu, fɔ fɛt, fɔ traŋa, fɔ rili rɛst, fɔ vɛks pasmak ɛn fɔ du tin pasmak, ɔ fɔ gɛt prɔblɛm fɔ slip, kɔl yu dɔktɔ wantɛm wantɛm. Tɛl yu famili ɛn aks dɛn fɔ wach fɔ dɛn chenj ya bak.
- Yu kin fil lɛk se yu de slip ɔ yu diziz. So, te yu no aw dis mɛrɛsin de afɛkt yu, nɔ drayv, yuz mashin, ɔ du ɛnitin we nid fɔ pe atɛnshɔn. Nɔ grap ɔ sidɔm kwik kwik wan, mɔ if yu dɔn ol. If yu du dat, i go mek yu nɔ gɛt bɔku chans fɔ mek yu ed de tɔn ɛn fɔdɔm.
- Rɔm kin ambɔg di wok we dis mɛrɛsin de du, so nɔ drink rɔm.
- Dis mɛrɛsin kin mek yu yay dray ɛn yu nɔ kin si fayn. If yu wɛr kɔntakt lens, yu kin gɛt sɔm prɔblɛm dɛn. Fɔ rɔb di ay drɔp dɛn kin ɛp. If dis prɔblɛm de kɔntinyu ɔ i rili bad, go to dɔktɔ fɔ di yay.
- Dray mɔt kin bi prɔblɛm. If yu chef gɔm we nɔ gɛt shuga, we yu sok had kandy we nɔ gɛt shuga, ɛn drink bɔku wata, dat kin ɛp yu. If dis prɔblɛm de kɔntinyu ɔ i de kam tranga, tɔk to yu dɔktɔ.
- Kɔnsul yu dɔktɔ bifo yu tek ɛni mɛrɛsin fɔ yusɛf fɔ tin dɛn lɛk kɔf, kol, ɛn alɛji. Dɔn bak, nɔ tek ɛni mɛrɛsin fɔ mek yu nɔ gɛt bɔku bɔku bɔdi we yu dɔktɔ nɔ gri fɔ tek yu wet. Di tin dɛn we de insay sɔm pan dɛn prɔdak ya kin mek di sayd ɛfɛkt dɛn bɔku.
- Dis mɛrɛsin kin afɛkt di blɔd shuga lɛvɛl. If yu gɛt dayabitis, tɔk to yu dɔktɔ bifo yu chenj di it we yu de it ɔ di doz fɔ yu dayabitis mɛrɛsin.
- If yu go gɛt ɛni ɔpreshɔn, mɛdikal tɛst, ɔ prɔsidyu, tɛl yu dɔktɔ se yu de tek dis mɛrɛsin. Bɔku tɛm, dɛn kin nid fɔ stɔp dis mɛrɛsin lɛk 10 dez bifo dɛn du ɔpreshɔn we dɛn kin pik fɔ du.
- Dis mɛrɛsin kin mek yu gɛt smɔl vaytamɛn B6. So mek shɔ se yu de gɛt inof vaytamɛn B6 we yu de tek dis mɛrɛsin. Tɔk to yu dɔktɔ bɔt di it ɛn vaytamɛn dɛn we yu de tek.
Wetin na di sayd ɛfɛkt dɛm we dis mɛrɛsin kin gɛt?
Lɛk ɔl di mɛrɛsin dɛn, Isocarboxazid kin mek sɔm pipul dɛn gɛt sayd ɛfɛkt. Sɔm siriɔs, sɔm nɔ so siriɔs.
Di sayd ɛfɛkt dɛm we yu fɔ tɛl yu dɔktɔ wantɛm wantɛm:
If yu gɛt ɛni wan pan dɛn sik ya, tɛl yu dɔktɔ we nɔ de te :
- Alɛji : Skin de rɔsh, it, rɛd spat na di skin, swel na di fes, lip, tɔng ɔ trot.
- Serotonin Syndrome Symptoms : Yu kin vɛks, yu kin kɔnfyus, yu at kin bit fast ɔ yu nɔ kin bit ɔltɛm, yu mɔsul dɛn kin stif ɔ yu kin twit, yu kin swet pasmak, yu kin gɛt ay fiva, yu kin gɛt sik, yu kin kol, yu kin vɔmit, yu kin gɛt dayarɛa. Dɛn tin ya kin bi sayn fɔ wan denja sik we dɛn kɔl Serotonin Syndrome, bikɔs dis mɛrɛsin de mek di lɛvɛl we di sɛrotonin de na di bren go ɔp.
- Di sayn dɛm fɔ di liva injuri : Pen na di ɔp rayt bɛlɛ, yu nɔ de want fɔ it, yu nɔ de fil fayn, yu de stɔl we gɛt layt kɔlɔ, yu urine we gɛt dak yɔlɔ ɔ brawn, yu skin ɔ yu yay de yɔlɔ, yu wik ɔ taya we nɔ kɔmɔn.
- Lɔw blɔd prɛshɔn : Diziz, fɔdɔm, nɔ de si fayn.
- Di sik dɛn we kin mek pɔsin sik .
- blɔd prɛshɔn we de go ɔp bad bad wan : Wantɛm we yu ed de at bad bad wan, yu nɔs, yu de vɔmit, yu nɛk stif, yu at bit kwik ɔ i nɔ de bit ɔltɛm (dis kin bi sayn fɔ `Tyramine` riakshɔn).
- Tin fɔ tink bɔt fɔ kil yusɛf ɔ fɔ du bad to yusɛf, fɔ mek yu fil bad, ɛn fɔ gɛt mɔ pwɛl at .
Sayd ɛfɛkt dɛn we nɔ kin rili denja, bɔt dɛn fɔ ripɔt to di dɔktɔ if dɛn kɔntinyu fɔ de:
Bɔku tɛm, dɛn sayd ɛfɛkt ya nɔ kin siriɔs, bɔt if dɛn kɔntinyu ɔ de mɔna yu, tɛl yu dɔktɔ:
- Banbɛlɛ
- Diziz we pɔsin kin gɛt
- Dray mɔt
- Ed de at
- Vɔmit
- Di we aw pɔsin kin shek shek
If yu notis ɛni ɔda kayn ɔr nyu sayn wae yu de tek dis mɛrɛsin wae nɔr de na di list, tɛl yu dɔktɔ. Yu kin ripɔt bak di sayd ɛfɛkt to di FDA na 1-800-FDA-1088.
Aw yu kin kip dis mɛrɛsin?
- Kip dis mɛrɛsin usay pikin ɛn animal dɛn we yu lɛk nɔ go ebul fɔ rich .
- Stɔr na rum tɛmpracha (bitwin 15 ɛn 30 digri sɛlshiɔs / 59 ɛn 86 digri Fahrenheit). Kip di mɛrɛsin bɔtul/paket tayt tayt wan .
- Nɔ yuz mɛrɛsin dɛn we dɔn pas. Trowe dɛn go.
Aw fɔ trowe mɛrɛsin we yu nɔ yuz ɔ we dɔn pas:
- Program dɛn de fɔ tek mɛrɛsin bak. Yu kin no bɔt dɛn na yu famasi ɔ na di polis.
- If dat nɔ pɔsibul, chɛk di mɛrɛsin lɛbl ɔ di liflet we de insay fɔ si if dɛn fɔ trowe am na di dɔti ɔ flɔsh am dɔŋ di tɔylɛt. If yu nɔ shɔ, aks yu dɔktɔ.
- If i sef fɔ trowe di dɔti, pul di mɛrɛsin kɔmɔt na di kɔntena. Miks am wit ɔda tin lɛk pusi dɔti, dɔti, ɔ kɔfi grɔn. Put di miksɔp insay bag ɔ kɔntena, sial am fayn fayn wan, ɛn trowe am na dɔti.
Fɔ dɔn, tin dɛn we wi fɔ mɛmba
`Isocarboxazid` na wan impɔtant mɛrɛsin fɔ trit pwɛl hat. Bɔt bikɔs i de na di `MAOI` klas, i kin mek siriɔs intarakshɔn wit it (espɛshali it dɛn we gɛt `Tyramine`) ɛn ɔda mɛrɛsin dɛn.
We yu de tek dis mɛrɛsin, tek tɛm bad bad wan bɔt di chenj dɛn we de apin na yu maynd, mɔ we yu de tink bɔt fɔ kil yusɛf. If yu gɛt ɛni prɔblɛm, tɛl yu dɔktɔ wantɛm wantɛm. Tek di rayt doz, di rayt tɛm, jɔs lɛk aw yu dɔktɔ tɛl yu. Na da tɛm de nɔmɔ yu go ebul fɔ gɛt di bɛst pan dis mɛrɛsin ɛn mek yu maynd gɛt wɛlbɔdi.
Dis atikul na jɔs sɔm tin dɛn. If yu gɛt ɛni ɔda kwɛstyɔn bɔt dis mɛrɛsin, duya tɔk to yu dɔktɔ, fama, ɔ ɔda pɔsin we de kia fɔ yu wɛlbɔdi biznɛs.
` Isocarboxazid, MAOI, dipreshɔn, mental wɛlbɔdi, dopamin, sɛrotonin, tyramine, sayd ifɛkt, drɔg intarakshɔn
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