Bɔku tɛm, tritmɛnt fɔ kansa kin tranga ɛn i nɔ kin izi fɔ waka. Wi no se difrɛn tin dɛn kin apin to di bɔdi we dɛn de du dis tritmɛnt. Bɔt spɛshal mɛrɛsin dɛn de we kin protɛkt yu frɔm dɛn sayd ɛfɛkt dɛn de ɛn ɛp fɔ mek di waka izi smɔl fɔ yu. Tide wi go tɔk bɔt dis kayn "ɛlpa" we de protɛkt wan impɔtant pat na yu bɔdi we yu de trit kansa. Dat na di Mesna vaysin.
Wetin na Mesna? Fɔ tɔk am simpul wan...
Imajin se dɛn gi yu wan kemotɛrapi drɔg we dɛn kɔl `ifosfamide` fɔ kansa. Dis drɔg rili pawaful fɔ kil kansa sɛl dɛn. Bɔt i kin mek yu blad pwɛl sɔm tin dɛn bak, mɔ we yu de blɔd wit yu urine.
Dis na di say we wan drɔg we dɛn kɔl Mesna de kam in. Mesna nɔto kansa drɔg. i de akt lεk "bodiguard" fכ di blad. Di men wok we Mesna de du na fɔ mek i nɔ pwɛl di blad we ifosfamide kin du ɛn fɔ mek i nɔ blɔd.
di imכtant tin na dat, Mesna de כnli mek di blad bכdi we di drog `ifosfamide` kכz. I nɔ kin ebul fɔ mek ɔda bad bad tin dɛn we kin apin we pɔsin gɛt kansa, lɛk we in ia kin lɔs ɛn we i kin gɛt nɔys.
Di impɔtant tin dɛn we yu fɔ tɛl yu dɔktɔ bifo yu yuz dis mɛrɛsin na:
Bifo yu bigin fɔ tek Mesna tritmɛnt, i impɔtant fɔ mek yu dɔktɔ no gud gud wan bɔt yu wɛlbɔdi kɔndishɔn. Mek shɔ se yu tɛl am bɔt dɛn tin ya mɔ:
- If yu gɛt ɔtoimyun sik: Fɔ ɛgzampul, if yu gɛt sik dɛn lɛk lupus, nephritis (wan sik we kin afɛkt di kidni dɛm), ɔr rεumatoid arthritis (wan inflammatory condition of the joints).
- If yu gɛt ɛni alɛji: Tɛl yu dɔktɔ if yu gɛt alɛji fɔ Mesna, fɔ bɛnzil alkol, we kin de insay di mɛrɛsin, fɔ mɛrɛsin we gɛt sɔlfɔ, fɔ ɛni ɔda mɛrɛsin, fɔ it, fɔ day, ɔ fɔ tin dɛn we de mek yu nɔ pwɛl.
- If yu gɛt bɛlɛ, yu de tray fɔ gɛt bɛlɛ, ɔ yu de gi pikin in bɛlɛ: I rili impɔtant fɔ tɛl yu dɔktɔ bɔt dɛn tin ya.
Aw dɛn kin gi di Mesna vaysin?
Dis mɛrɛsin nɔto sɔntin we yu kin kɛr go na os. Na injεkshכn we dεn kin gi insay wan vein, lεk salin. So na pɔsin we de kia fɔ wɛlbɔdi biznɛs na ɔspitul ɔ klinik de gi am. So yu nɔ nid fɔ wɔri bɔt fɔ mis wan doz ɔ fɔ mis wan doz.
Pikin dɛn kin nid spɛshal kia we dɛn de gi dis mɛrɛsin. Yu dɔktɔ we de mɛn pikin dɛn go disayd dis ɛn gi am as nid de.
Wetin a go du if a tek bɔku mɛrɛsin?
Dɛn kin gi dis na ɔspitul, so di chans fɔ mek dis apin rili smɔl. Bɔt if yu tink se yu dɔn tek di mɛrɛsin pasmak, go to di Nashɔnal Pɔyzin Infɔmeshɔn Sɛnta na di Kɔlɔmbɔ Nashɔnal Ospital wantɛm wantɛm . Ɔ go na di Imejɛnsi Tritmɛnt Yunit (ETU) we de nia yu .
Tin dɛn we wi fɔ pe atɛnshɔn mɔ to we wi de tek dis mɛrɛsin:
Yu dɔktɔ go de wach yu kɔndishɔn ɔltɛm we yu de trit yu Mesna, ɛn i impɔtant fɔ mek yu no bɔt dɛn tin ya.
1. Drink plɛnti wata: Yu fɔ drink at le wan lita wata (lɛk 4 glas) ɛvride we yu de tek dis mɛrɛsin. Dis go ɛp fɔ mek yu blad klin.
2. Pe atɛnshɔn to di kɔlɔ we yu urine gɛt: If yu notis se yu urine de tɔn pink ɔ rɛd, i kin bi sayn fɔ se yu de blɔd. As yu notis dis so, tɛl yu dɔktɔ ɛn nɔ de te.
3. Skin chenj: Sɔntɛnde, siriɔs skin kin apin ivin sɔm wiks afta yu dɔn bigin dis mɛrɛsin. Wach fɔ dɛn sayn ya:
- Wan rash we kin kam wantɛm wantɛm wit sɔm sayn dɛn lɛk fiva ɛn kol.
- Di lɛsin dɛn kin tɔn rɛd ɔ pepul, dɔn dɛn kin tɔn to blista ɔ di skin kin kɔmɔt.
- Rɛd, it skin wit swɛlin limf no dɛm na yu fes, lip, nɛk, ɔ armpit.
If yu si sɔntin lɛk dis, go to dɔktɔ wantɛm wantɛm.
Wetin na di bad tin dɛn we kin apin to pɔsin?
Lɛk ɛni mɛrɛsin, Mesna kin mek sɔm sayd ɛfɛkt dɛn. Sɔm pan dɛn tin ya fɔ ripɔt wantɛm wantɛm, ɛn ɔda wan dɛn nɔ siriɔs.
| Sayd Ifɛkt we i kin gɛt |
|---|
| Siriɔs sayd ɛfɛkt dɛm we yu fɔ ripɔt to yu dɔktɔ wantɛm wantɛm |
| Alɛji lɛk we yu skin de rɔsh, it ɔ ayv, yu fes, yu lip ɔ yu tɔng de swel |
| I nɔ kin izi fɔ yu fɔ blo |
| Blɔd na di urine ɔ pink/rɛd urine |
| Fiva, kol, ɔ trot we de at |
| Di skin we de rɛd ɔ we de flash |
| Sɔl dɛn na yu mɔt |
| Pen ɔ rɛdnɛs na di say we dɛn injekt |
| Rɛd, blista, pil pan di skin (ivin insay di mɔt) . |
| Anklɛ ɔ fut we de swel |
| Fɔ vɔmit |
| Sayd ɛfɛkt dɛm we dɛn fɔ ripɔt to di dɔktɔ if dɛn kɔntinyu ɔ de mɔna am |
| Bɔdi de at ɛn pen |
| Fɔ fil wan teys we nɔ fayn na yu mɔt |
| Rɔnbɛlɛ |
| Diziz we pɔsin kin gɛt |
| Di ia we de lɔs |
| Ed de at |
| Vɔmit |
If yu gɛt ɛni ɔda kayn sik we nɔ kɔmɔn we dɛn nɔ tɔk bɔt na dis list, duya tɛl yu dɔktɔ bɔt dɛn bak.
Mɛsej we dɛn kin kɛr go na os
- Mesna nɔto wan mɛrɛsin we de mek pɔsin gɛt kansa. Na wan mɛrɛsin we de protɛkt pɔsin we de mek di blad nɔ pwɛl we di kansa drɔg `ifosfamide` de mek.
- Bifo yu bigin fɔ trit yu, tɛl yu dɔktɔ bɔt ɔl yu mɛrɛsin ɛn alɛji.
- Nɔ fɔgɛt fɔ drink bɔku wata di de dɛn we yu de tek dis mɛrɛsin.
- If yu urine tɔn rɛd/pink ɔ yu notis siriɔs skin riakshɔn, tɛl yu dɔktɔ wantɛm wantɛm.
- Bikɔs dɛn kin gi dis mɛrɛsin na ɔspitul, yu nɔ nid fɔ wɔri fɔ mis wan doz ɔ fɔ gɛda am.
- If yu gɛt ɛni kwɛstyɔn ɔ dawt bɔt dis mɛrɛsin, nɔ fred fɔ aks yu dɔktɔ.
👩🏽 ⚕️ Ɔda kwɛstyɔn dɛn (FAQ dɛn)
💬 Mesna / Mesnex vaccine/pills na wan mɛrɛsin we dɛn kin gi fɔ us sik?
Dis nɔto ɔdinari pil/antikansa drɔg! Dis na di onli layf-sev (Chemoprotectant) drɔg we kin stɔp Ɛmorajik Sistayt (blɔd wit urine) ɛn ‘protɛkt di blad 100%’ fɔ kansa sik pipul dɛn we dɛn kin gi kansa injɛkshɔn we rili siriɔs/pɔtɛnt we dɛn kɔl ‘Cyclophosphamide (Cytoxan)’ ɛn ‘Ifosfamide’, we na di pɔyzin we de kil (Acrolein) we dɛn mek bay dɛn injɛkshɔn dɛn de, we kin wund di pɔsin in blad kpatakpata ɛn mek i blɔd!
💬 We kansa vaysin go bɔn di blad, aw dis vaysin (Mesna) de protɛkt di blad?
We dɛn gi di kansa vaysin (Ifosfamide) to di bɔdi, i de mek wan pɔyzin we dɛn kɔl ‘Acrolein’ we so bad dat i de bɔn di blad in bɔdi. Dis pɔyzin kin go na di blad. Bɔt if dɛn gi dis ‘Mesna’ injɛkshɔn bifo dɛn gi di kansa drɔg, i go go dairekt to di blad (Thiol grup de tay Acrolein) ɛn tɔn da bad bad pɔyzin de to sɔntin we nɔ bad, lɛk swit wata! Dɔn dɛn kansa vaysin dɛn de go jɔs kil di kansa ɛn nɔ go ambɔg di blad.
💬 Wetin na di mistek ɛn sayd ɛfɛkt dɛm we pipul dɛn we de yuz dis drɔg (Mesna) fɔ rili no bɔt?
Di big mistek we pipul dɛn kin tink na dat dis nɔ de protɛkt ɔda ɔgan dɛn pas di blad (liva, kidni, nɛv) frɔm di denja dɛn we da kansa drɔg de gɛt (ɔda sik dɛn go kam ɛni we)! Dɔn bak, afta dɛn dɔn tek dis mɛrɛsin, sɔm pipul dɛn kin gɛt alɛji (Hypersensitivity) ɛn gɛt rash ɔlsay na dɛn bɔdi ɛn dɛn blɔd prɛshɔn kin go dɔŋ to ziro. Wan ɔda tin we de mɔna yu na dat ivin if yu tek am bay mɔt ɔ injɛkt am, yu go mɔs gɛt ‘Nɔs/Vɔmit’ we yu nɔ go ebul fɔ bia.
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