Sɔntɛnde wi kin gɛt kɔf ɛn mɔkus we kin stɔp na wi trot ɛn chɛst, nɔto so i kin rili at? We di mכkus stכp na wi chεst we i nכ kכmכt, i kin fil lεk se wi nכ ebul fכ brith. Dis na tin we kin rili anɔynt ɛn mek dɛn at pwɛl fɔ di wan dɛn we gɛt lɔng tɛm lɔng sik lɛk asma ɛn COPD. Dɛn kayn tɛm dɛn de, wi de tɔk bɔt wan spɛshal kayn mɛrɛsin we de ɛp fɔ sɔlv da tik, stika mכkus de ɛn pul am izi wan. Dis na wetin dɛn kɔl Mucolytic mɛrɛsin na mɛrɛsin.
Wetin na mucolytic? Lɛ wi ɔndastand am simpul wan.
Okay, mek wi ɔndastand dis wit wan rili simpul ɛgzampul. Imajin se di mכkus we de insay yu lכng dεm tan lεk tik tik gכm we de stika. Dis gɔm kin mek di smɔl smɔl say dɛn we yu de blo na yu lɔng dɛn nɔ ebul fɔ blo, ɛn dis kin mek i nɔ izi fɔ blo. Nɔto dat nɔmɔ, dis tik tik mכkus de mek bak di jεm dεm trכp insay, we de mek i izi fכ yu go sik.
Mucolytics de ɛp fɔ mek da tik mucus de we tan lɛk gɔm, lɛk wata, tan. Fɔ tɔk di kɔrɛkt tin, dɛn kin brok di kemikal dɛn we kin mek di mɔytiks tik. We di mכkus tin, yu kin kכf am izi wan. I kin mek i izi fɔ blo, ɛn yu chɛst kin fil fayn pasmak.
Dis Mucolytic na pat pan wan big klas fɔ drɔgs. Wi kɔl da klas de mucoactive agents . Dat min se ɛni drɔg we de afɛkt di mɔkus difrɛn we dɛn ɛn ɛp fɔ klin am frɔm di lɔng dɛn na dis klas. Fɔ ɛgzampul, sɔm pan di tin dɛn we wi kin tek fɔ mek pɔsin kɔf nɔmal fɔ mek i kɔf kin mek di mɔk de bɔku, i kin mek i gɛt wata, ɛn ɛp fɔ mek i kɔmɔt. Bɔt Mucolytics difrɛn smɔl. dεn de afekt di tik mכkus mכlikul dεm sεf dεn dεn wan dεm.
Aw dis mucolytic mεdisin de wok insay di bכdi?
Fɔ ɔndastand dis, wi nid fɔ no smɔl fɔs bɔt aw wi lɔng dɛn kin klin dɛnsɛf bay insɛf.
Nɔmal wan, pɔsin we gɛt wɛlbɔdi in lɔng dɛn kin mek sɔm kayn mɔk ɔltɛm. Natin nɔ bad wit dat. Dis mכkus mεmbran rili imכtant. Bikɔs we wi de blo, na dis mכkus mεmbran de trap tin dεm we wi nכ want lεk dכst, pכlεn, εn jεm dεm we de go insay di briz εn protεkt di lכng dεm bay we i de mek dεn nכ go insay.
Dɔn, insay di say dɛn we wi de blo, bɔku bɔku tin dɛn de we rili fayn ɛn we tan lɛk ia. Lɛk di brist dɛn we de na smɔl brum. Wi kin kɔl dɛn cilia ya . dis cilia dεm de kip de muv na di sem dairekshכn, we de tכwεd di trot. Lɛk wef dɛn we de na di si. dis muvmεnt de push di mכkus we dεn kכl di jεm dεm sכmtεm sכmtεm to di trot. Dɔn, we wi nɔ no, wi kin swɛla da mכkus de, ɔ wi kin kɔf am, spit am. Dis na wɔndaful natura l prɔses we wi bɔdi gɛt fɔ kip wi lɔng dɛn klin.
Bɔt pan sɔm sik dɛn we kin gɛt lɔng tɛm na di lɔng, dis kin ambɔg.
- di mכkus we dεn de prodyuz de inkrεs bכku bכku wan.
- di mכkus we de fכm kin rili tik εn stika.
- Sɔm sik dɛn kin mek dɛn cilia dɛn de wok wik.
biכs fכ dεn rizin dεm ya, dεn nכ kin push di mכkus kכmכt εn i kin stכk insay di lכng dεm. Dis kin mek i nɔ izi fɔ blo ɛn i kin mek pɔsin gɛt infɛkshɔn.
Mucolytic mεdikeshכn dεm de εp wit dis mεs. Dɛn kin go stret fɔ brok di kemikal bond dɛn we de insay da tik, stika mכkus de, ɛn mek i tan. Da we de, ivin dɛn cilia dɛn we wik kin push di mucus kɔmɔt izi wan. Ɛn, yu kin kɔf am we yu nɔ nid fɔ wok tranga wan.
Us sik dɛn dɛn kin yuz mucolytic drɔgs fɔ?
Dɛn mɛrɛsin ya nɔto fɔ di kɔmɔn kol ɔ kɔf. Bɔku tɛm, dɔktɔ kin gi dɛn to pipul dɛn we gɛt sik dɛn we nɔ de mɛn na dɛn lɔng we kin mek tik tik mucus.
- Sistik Faybrosis: Dis na sik we pɔsin kin gɛt we i kam pan jɛnɛtiks. Pipul dεm wae gεt dis sik kin gεt bכku tik mכkus na dεn bכdi, spεshal wan na dεn lכng εn pankrias. Dis kin mek pɔsin gɛt infekshɔn na in lɔng bɔku tɛm.
- Bronchiectasis: Dis kכndyushכn kin apin we di aywe dεm (bronchi) na di lכng dεm kin dכn pwεl fכ כltεm, i kin big, εn fulכp wit mכkus. Dis kin mek pɔsin de kɔf ɔltɛm ɛn gɛt infɛkshɔn.
- Chronic Obstructive Pulmonary Disease (COPD): Dis na wan sik wae kin kam pan pɔrsin wae kin kam pan pɔrsin wae de smok fɔ lɔng tɛm. Dɛn tu tin ya we dɛn kɔl ɛmfisema ɛn kronik brɔnkayt de ɔnda dis kategori. di men sayn dεm fכ dis na bak tik mכkus prodakshכn εn i at fכ brith.
- Asma: Sɔm pipul dɛn we gɛt asma kin gɛt tik tik mɔk bak. If na so i bi, dɛn kin gi yu dis mɛrɛsin bay wetin di dɔktɔ disayd.
Wetin na di kayn Mucolytics we dɛn kin yuz mɔ?
Tu kayn Mucolytics de we dɛn kin yuz mɔ na Sri Lanka ɛn di wɔl.
1. Asetil sistayn: dεn kכl am bak N-asetil sistayn, N-asetil-L-sistayn, כ NAC fכ sכt. Mucomyst® na wan brand nem we pipul dɛn sabi fɔ dis mɛrɛsin. Na gud tin we de mek di blɔd tan, ɛn i gɛt bak anti-inflammatory ɛn antioxidant prɔpati.
Dis Acetylcysteine mɛrɛsin gɛt ɔda bɛnifit we de mek pɔsin sɔprayz, we de sev layf. Dɛn kin gi dis mɛrɛsin bak na ɔspitul tru di IV (intravenous) we fɔ mek di liva nɔ pwɛl if wi tek tumɔs pan di mɛrɛsin we wi kin tek fɔ fiva ɛn bɔdi pen, we dɛn kɔl Paracetamol (we dɛn kin kɔl bak Tylenol®), we na ɔvados.
2. Dornase Alfa (ோனேஸ அலா): Pulmozyme® na di brand nem fɔ dis. Dis na mɛrɛsin bak we de mek di blɔd nɔ tan lɛk. Bɔt dɛn kin advays dis fɔ di wan dɛn we gɛt Sistik Faybrosis. I nɔ fayn fɔ di wan dɛn we gɛt Bronchiectasis we nɔ gɛt Sistik Faybrosis.
Aw fɔ tek dis mɛrɛsin? (Di we aw dɛn kin yuz am)
Bɔku we dɛn de fɔ gi dis mucolytic mɛrɛsin to di bɔdi. Yu dɔktɔ go disayd di we we go fayn fɔ yu bay aw yu de mɛn yu.
- Tru Nebulizer: Dis na di we aw dɛn kin yuz mɔ. Yu go dɔn si we dɛn de gi pikin ɛn big pipul dɛn smɔl mask fɔ blo.Dɛn kɔl da mashin de nebulizer . Dɛn kin put dis mɛrɛsin insay dis mashin ɛn di pɔsin kin blo di fayn fayn vapour we tan lɛk mist we dɛn kin mek frɔm am fɔ sɔm minit. Dɔn di mɛrɛsin kin go dairekt insay di lɔng dɛn.
- bay IV (intravenous): Insay sɔm imejensi, mɔ pan kes dɛm lɛk Paracetamol ɔvados, dɛn kin gi dis mɛrɛsin dairekt insay di bɔdi tru wan kanula we dɛn put insay wan vein.
- Oral: Na sɔm kɔntri dɛn, dɛn kin gɛt dis mɛrɛsin bak lɛk tablɛt ɔ sachet we dɛn kin sɔlv insay wata ɛn tek am bay mɔt.
Mucolytic ɛn Expectorant: Wetin na di difrɛns bitwin di tu?
Dis na say we bɔku pipul dɛn kin kɔnfyus. Yu kin tink se, "Nɔto ɔl kɔf srɔp dɛn na di sem?" Bɔt nɔto so i bi. Mucolytics ɛn expectorants na tu kayn mɛrɛsin we de ɛp fɔ klin di mucus, bɔt dɛn de wok tu difrɛn we dɛn.
| Di kwaliti we pɔsin gɛt | Mucolytic we de mek pɔsin gɛt bɔdi | Expectorant we de mek pɔsin kɔmɔt |
|---|---|---|
| Aw i de wok | I de brok di mכkus bay we i de brok di kεmikכl bכnd dεm na di mכkus we dεn כlrεdi tik εn stika. | I de mek di mɔs we de na di say we yu de blo bɔku, i de mek di mכkus fכ fכm bכku, εn i de εp fכ pul mכkus kכmכt . |
| Men yus | Fɔ lɔng tɛm (krɔnik) lɔng sik dɛm lɛk COPD, Sistik Faybrosis, Bronchiectasis. | Sɔt tɛm kɔf ɛn flug we kin kam bikɔs ɔf tin dɛn lɛk kɔmɔn kol ɛn fluFɔ. |
| Di tin dɛn we pɔsin kin gɛt | Bɔku tɛm, dɛn kin nid fɔ gɛt prɛskrishɔn frɔm dɔktɔ . | Bɔku pan di mɛrɛsin dɛn kin bay ɔva-di-kɔnta (OTC) na di famasi we yu nɔ gɛt prɛskrishɔn. |
| Ɛgzampul dɛn | Asetilsistayyn, Dɔrnaz alfa | Guaifenesin (dɛn kin si am na bɔku kɔf srɔp dɛn) . |
Ɛni bad bad tin dɛn de we kin apin to am? Tin dɛn we wi fɔ no bɔt
Lɛk ɛni mɛrɛsin, di mucolytics kin mek sɔm sayd ɛfɛkt, pan ɔl we nɔto ɔlman kin gɛt dɛn.
Pipul wae gɛt asma fɔ tek tɛm mɔ wae dɛn de tek Acetylcysteine. dis na biכs sכmtεm dis mεdisin kin mek di brכnkiol dεm kכnstrikt mכr. Dɛn kɔl dis brɔnkɔspasm . So, if yu gɛt asma, yu fɔ rili tɛl yu dɔktɔ bifo yu tek dis mɛrɛsin. If nid de, i kin gi am ɔda mɛrɛsin (bronchodilator) we de opin di say dɛn we di briz de blo wit dis mɛrɛsin.
Di sayd ɛfɛkt dɛn we dɛn kin si:
- Nɔs ɔ vɔmit
- Indigestion ɔ bloating
- Skin rash ɔ it
- Trot de at
- Voys chenj ɔ lɔs vɔys
- I nɔ izi fɔ blo (dyspnea) .
- Chɛst de pen
Wan ɔda tin, dis Acetylcysteine mɛrɛsin gɛt smɔl bad smel. Bɔku pipul dɛn se i de smɛl lɛk rɔtin eg. Nɔto sik, na jɔs di natura kemikal kɔmpɔzishɔn fɔ di mɛrɛsin. So nɔ wɔri bɔt am.
Ustɛm a fɔ go to dɔktɔ?
We yu de yuz dis mɛrɛsin, mek shɔ se yu tɔk to yu dɔktɔ pan dɛn tin ya:
- If yu gɛt ɛni kwɛstyɔn ɔ dawt bɔt di mɛrɛsin we dɛn gi yu.
- If yu gɛt ɛnitin we nɔ fayn, we yu nɔ bin de ɛkspɛkt, ɔ we rili bad afta yu dɔn tek di mɛrɛsin.
- If yu fil lɛk se yu sik nɔ de bɛtɛ pan ɔl we yu de yuz di mɛrɛsin.
- If yu gɛt asma ɛn yu gɛt prɔblɛm fɔ blo afta yu dɔn tek dis mɛrɛsin, go to tritmɛnt kwik kwik wan .
Di tin we impɔtant pas ɔl na, nɔ ɛva yuz dɛn mɛrɛsin ya if yu nɔ gɛt dɔktɔ in advays. Nɔ tink se wetin bin wok fɔ yu padi go wok fɔ yu. Ɔlman in bɔdi ɛn in kɔndishɔn difrɛn.
Mɛsej we dɛn kin kɛr go na os
- Mucolytic na wan kayn mεdikal we de εp fכ tכn di tik, stika mכkus na di lכng εn mek i izi fכ kכl am.
- Dɛn kin yuse dɛn tin ya fɔ sik dɛn we nɔ de dɔn lɛk COPD ɛn Sistik Faybrosis, nɔto fɔ di kɔmɔn kol.
- Dis mɛrɛsin fɔ jɔs tek we dɔktɔ tɛl yu fɔ tek am .
- If yu gɛt asma, i rili impɔtant fɔ tɛl yu dɔktɔ bifo yu tek dis mɛrɛsin.
- If yu gɛt ɛni ɔda kayn sik ɔ sayd ɛfɛkt we yu de yuz di mɛrɛsin, tɛl yu dɔktɔ wantɛm wantɛm.
- Mucolytics ɛn ova-di-kɔnta kɔf srɔp (expectorants) na tu difrɛn tin. Nɔ kɔnfyus di tu.
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