Wi fɔ lan bɔt mɔt/bɛlɛ ɔlsa (mucositis) we kin kam wit kansa tritmɛnt?

We yu de du tritmɛnt fɔ kansa, sɔntɛnde yu kin gɛt pen we yu nɔ go ebul fɔ bia insay yu mɔt ɛn yu trot, nɔto so? Sɔntɛnde, yu nɔ kin ivin ebul fɔ it ɔ drink, ɛn i nɔ kin izi fɔ tɔk. Na da sik de wi go tɔk bɔt tide, we dɛn kɔl mucositis . Nɔ wɔri, dis na tin we kin apin to bɔku pipul dɛn, ɛn we dɛn de fɔ manej am. Lɛ wi tek tɛm luk am gud gud wan.

Wetin na Mucositis? Fɔ tɔk am simpul wan...

Mucositis na inflameshn ɛn injury na di layn na wi gastrointestinal (GI) tract , ɔ mucosa . Tink bɔt am lɛk di wet, smol, pink layn na wi mɔt. Dat na di layn we de layn wi ɔl di dijestiv trakt. Na in de protɛkt wi frɔm jem ɛn di harsh kemikal dɛn we de insay wi it.

Bɔt sɔm tritmɛnt dɛn we dɛn kin yuz fɔ mɛn kansa, mɔ di kemotɛrapi , redyushɔn tɛrapi , ɔ stem sɛl transplant , lɛk fɔ transplant bon mɛro , kin pwɛl dis dilik layn. Dis na we di mucositis de apin. dis kכndyushכn dεn kin si am mכst na di mכt as כral mכkosaytis .

Aw dis mכkus de afekt wi bכdi?

Naw, luk, kansa sɛl na wan kayn sɛl we kin sheb kwik kwik wan. So, dɛn mek di tritmɛnt dɛn we dɛn kin gi fɔ kansa fɔ pwɛl dɛn sɛl dɛn de we kin sheb kwik kwik wan. bכt di prכblεm na dat, di sεl dεm na wi mכkus mεmbran dεm bak na wan kayn sεl we de sheb εn nyu kwik kwik wan. So, di tritmɛnt fɔ kansa nɔ kin ebul fɔ no di difrɛns bitwin di tu. So, wit di kansa sel dεm, di sεl dεm we de insay wi protεktiv mεmbran dεm dεm dεn de pwεl bak.

nכmal wan, dis mכkus mεmbran de protεkt wi biכs i de rigεnεret kwik kwik wan. Ivin smɔl wund kin wɛl kwik kwik wan. bכt insay mכkusaytis, nכto nכmכ di sεl dεm na dis mεmbran de pwεl, bכt di abiliti fכ dεn sεl dεm fכ rigεnεret εn hεl wund dεm de rεdכks bak. Wetin kin apin da tɛm de? dis mεmbran de bigin fכ pwεl mכr bay כdinari tin dεm lεk fכ it εn tכk. Nɔto dat nɔmɔ, bɔt di risk fɔ gɛt infɛkshɔn kin bɔku bak.

Insay ɔral mucositis, di insay pat pan di mɔt kin rɛd, shayn, swel, ɛn sɔl kin kɔmɔt. Sɔntɛnde , wayt pat dɛn we gɛt pus kin kɔmɔt na di mɔt. Sɔm pipul dɛn nɔ kin fil pen, bɔt ɔda pipul dɛn kin fil pen we dɛn nɔ go ebul fɔ bia. Dɔktɔ dɛn dɔn sheb dis pen to lɛvul dɛn. Levεl 1 εn 2 na sכm kayn pen, bכt lεvεl 3 εn 4 na siriכs pen. Insay dɛn kayn bad bad tin ya, yu nɔ go ebul fɔ it ɔ drink, ɛn ivin di tritmɛnt fɔ kansa kin gɛt fɔ ridyus.

Sɔm pipul dɛn kin gɛt gastrointestinal mucositis, nɔto jɔs na dɛn mɔt, bɔt na dɛn intestinal bak. Dis kin mek yu gɛt sɔm sayn dɛm lɛk bɛlɛ pen, nɔs, ɛn vɔmit . If i de nia di bɛlɛ, dɛn sayn ya kin apin. If inflamɛns de na di kɔlon, yu kin gɛt dayarɛa ɔ pen we yu de muv yu bɔdi.

Udat kin gɛt mɔ sik?

Mukosaytis de divεlכ p pan lεk 50% pan di pipul dεm we de gεt kεmothεrapi, εn bitwin 80% εn 100% pan di pipul dεm we de du rεdyushכn tεrapi כ stεm sεl transplant. Dis min se i rili kɔmɔn.

Dɔn bak, yu kin gɛt bɔrku risk fɔ gɛt ɔr wɔs dis sik fɔ rizin dɛn lɛk:

• If yu de smok ɔ yu de it tabak .
• If yu de yuz rɔm pasmak.
• If di bɔdi nɔ gɛt wata .
• If prɔtin nɔ de .
• If yu bɔdi mas indeks (BMI) smɔl .
• If yu gɛt dɛnt implant ɔ yu de yuz dɛnt .
• If yu gɛt sik we de mek yu gɛt gɔm .
• If yu gɛt sik na yu kidni .
• If yu gɛt dayabitis mɛllitus .
• If yu gɛt HIV infɛkshɔn .

Wetin na di sayn dɛm fɔ Mucositis?

We inflamɛns apin, i kin mek i rɛd, i kin at, i kin wam, ɛn i kin swel . Along wit dis, e kin sho bak sayn wae de spεshal fכ εvri εria.

Di simptom dɛm fɔ ɔral mucositis:

• Di insay pat na di mɔt ɛn di gɔm kin rɛd, shayn, ɛn swel .
• Dray mɔt .
• Ekstra tik saliva .
• Ɔlsa na yu mɔt .
• Sɔft wayt pat dɛn we gɛt pus .
• I nɔ kin izi fɔ swɛla, tɔk, it, ɛn drink .
• Blɔd we de kɔmɔt .
• Wan wayt mucous coating pan di wayt na di mɔt.

Di simptom dɛm fɔ gastrointestinal mucositis:

• di mכkus mεmbran rεd (εrythematous mucosa) .
• Pɔsin we de fil pen na di bɛlɛ .
• Nɔs ɛn vɔmit .
• Rɔnbɛlɛ .
• Blɔd ɔ mכkus na yu poop .
• Di bɔdi we de muv yu bɔdi we de mek yu fil pen .

Wetin na di men tin dɛm wae kin mek pɔrsin gɛt mכkus?

We dɔktɔ dɛn kin tɔk bɔt mucositis, bɔku tɛm dɛn kin tɔk bɔt di inflamɛns we de na di layn na di mɔt ɛn di dijestiv trakt we kin kam bikɔs ɔf tritmɛnt dɛn we gɛt kansa. As wi bin dɔn tɔk, dɛn tritmɛnt ya kin pwɛl di sɛl dɛn we kin sheb kwik kwik wan, ivin di sɛl dɛn we de na wi myukɔs mɛmbran dɛn. di mכt כ di bεlε kin afekt dis we bay we dεn gi di כl bכdi we dεn de gi di כl bכdi we dεn de gi di mכt כ kεmothεrapi, כ we dεn gi di כl bכdi tritmεnt dεm we dεn gi am to wan patikyula εria nכmכ.

sכmtεm, inflameshn na di mכkus mεmbran kin apin wit כda kכndyushכn dεm, lεk infεkshכn. Bɔt afta dat, dɛn kin kɔl dɛn ɔda nem dɛn we rili spɛshal. Fɔ ɛgzampul, dɛn kɔl di inflamɛns na di mɔt stomatitis , ɛn inflamɛns na di mɔt bikɔs ɔf infekshɔn dɛn kɔl am gingivostomatitis .

Wetin na di prɔblɛm dɛn we kin apin we pɔsin gɛt Mucositis?

Dis na sɔntin we wi fɔ tek tɛm wit smɔl.

• Nɔ it fayn: If yu fil pen na yu mɔt, yu trot, yu it, ɔ yu bɛlɛ, dat kin mek i nɔ izi fɔ it ɔ drink. Dis kin rili siriɔs fɔ pipul dɛm wae gɛt kansa, wae dɔn ɔlrɛdi gɛt prɔblɛm wit fɔ it ɛn fɔ lɛf fɔ it bɔku bɔku it. I impɔtant fɔ gi dɛn gud it. Na lɛk 70% pan di pipul dɛn kin nid fɔ go na ɔspitul fɔ gi dɛn tiub.
• Dayarɛa we nɔ de dɔn: If yu gɛt dayarɛa ɔltɛm, ɔ if yu gɛt blɔd na yu stɔl, yu kin nid fɔ go na ɔspitul ɛn wach yu fɔ mek yu nɔ gɛt wata na yu bɔdi ɔ yu nɔ gɛt blɔd.
• Infεkshכn: We di mכkus mεmbran dεm dכn pwεl, wan pan di imכtant shild dεm we de protεkt na wi bכdi de lכs. Pipul dɛn we gɛt kansa nɔ kin gɛt bɛtɛ wayt blɔd sɛl, we min se dɛn imyun sistɛm bak kin wik. we wund dεm de divεlכp biכs fכ mכkusaytis, di jεm dεm kin go insay di bכdi. Pipul wae gɛt mucositis, wae de du kemotɛrapi, ɛn wae gɛt low wayt blɔd sɛl (neutropenia) kin gɛt siriɔs blɔd infekshɔn (septicemia).
• Ridyus di tritmɛnt fɔ kansa: If dɛn gɛt siriɔs mucositis, sɔm pipul dɛn we gɛt kansa kin gɛt fɔ delay ɔ ridyus dɛn tritmɛnt. Dis na ɔda prɔblɛm we kin ambɔg dɛn wɛlbɔdi. Dɛn se pas 30% pan di sik pipul dɛn kin stɔp tritmɛnt bikɔs ɔf dis kɔndishɔn.

Aw dɛn kin no se pɔsin gɛt Mucositis?

Mucositis na wan kɔmɔn sayd ɛfɛkt fɔ kansa tritmɛnt. Yu kin no am izi wan bay wae yu luk yu sayn dɛm, yu mɛrɛsin histri, ɛn di say dɛm wae yu gɛt inflamɛns. If yu gɛt gastrointestinal mucositis, luk insay imej tɛst.Yu go nid fɔ gɛt wan. Dɔn bak, yu dɔktɔ kin want fɔ chɛk if yu gɛt ɛni baktri ɔ fɛns infɛkshɔn. Dɛn kin du dis wit simpul blɔd tɛst .

Wetin na di tritmɛnt dɛm fɔ Mucositis?

Mucositis kin go insɛf afta yu kansa tritmɛnt dɔn. If yu de tek kimotɛrapi, di mucositis go apia insay wan ɔ tu wiks afta yu bigin fɔ trit yu ɛn i go dɔn insay wan to siks wik. If yu de tek redyushɔn tɛrapi, di mucositis go apia insay tu to tri wiks afta yu bigin fɔ trit yu ɛn i go go insay tu to 4 wiks afta yu dɔn di tritmɛnt. De tεm wae e kin tek fכ bεtε kin difrεn dipכnt pan aw e tranga εn aw yu de kia fכ am fayn so dat e nכ go wɔs. Pan ɔl we yu de wɛl, yu go nid dɛn tin ya:

Manejmɛnt fɔ di pen

Pen na di prɔblɛm we siriɔs pas ɔl wit di mucositis, mɔ we i de apin na di mɔt. Di tin dɛn we dɛn kin put pan pɔsin in bɔdi nɔ kin las fɔ lɔng tɛm ɔ i nɔ kin rich ɔl di say dɛn we dɛn de. Yu kin nid fɔ yuz ɔda kayn we fɔ kɔntrol yu pen. Yu kin nid fɔ was yu mɔt, mɛrɛsin fɔ mek yu nɔ gɛt pen we yu nɔ de bay, ɛn ivin opioid dɛn we dɛn kin gi yu. Nɔ tolɛret di pen. Yu nid fɔ ebul fɔ it ɛn drink fayn fɔ mek yu wɛl. Tɔk to yu dɔktɔ bɔt aw fɔ mɛn yu pen we yu de trit kansa.

Sɔm tritmɛnt dɛn we de mek pɔsin nɔ fil pen fɔ di sik we dɛn kɔl mucositis:

• tכpikכl anεsthεtik: dεn ya inklud tin dεm lεk `lidocaine`, `benzocaine`, `dyclonine hydrochloride (HCl)` εn `Ulcerease® (0.6% phenol)`.
• "Magic mouthwash": Dis na miksכp fכ `lidocaine`, `diphenhydramine`, εn `Maalox®`.
• Di mɛrɛsin dɛn we de mek pɔsin nɔ fil bad: Fɔ ɛgzampul, dɛn kin yuz prɛdnison.
• "GI kɔktɛl": Dis na miksɔp fɔ `Maalox®`, `Nystatin®` ɛn `Hurricane Liquid®`.
• Asetaminofen: I fiba `Tylenol®`.
• Di mɛrɛsin dɛn we dɛn kin gi yu fɔ mek yu fil pen: Dɛn fɔ tek dɛn tin ya wit tin dɛn we de mek yu stɔl sof fɔ mek yu nɔ gɛt kɔnstipɛshɔn.

Kia fɔ yu mɔt

We yu gɛt ɔral mucositis, yu nid fɔ tek kia spɛshal wan pan yu mɔt. Dis nɔ kin jɔs ridyus di pen, bɔt i kin protɛkt am bak frɔm ɔda damej ɛn infɛkshɔn. Ivin simpul tin dɛm lɛk fɔ it, tɔk, ɛn swɛla kin pwɛl yu myukɔs mɛmbran dɛm we wik. Dis min se yu fɔ pik sɔft it ɛn tin dɛn we go mek yu mɔt ɛn yu trot wet ɛn protɛkt. Bikɔs yu myukɔs mɛmbran dɛn we wik kin gɛt infekshɔn mɔ, i impɔtant bak fɔ klin .

Tritmɛnt fɔ ɔral mucositis:

• Brush yu tit mɔ – bɔt jisnɔ: At le tri to 4 tɛm insay di de. Yuz tut brɔsh we gɛt saf brist ɛn tut paste we gɛt fluoride we nɔ gɛt wan bɔt. Nɔ yuz tin dɛn we de mek pɔsin wayt. If tut paste de mek yu mɔt vɛks, yuz sɔl ɛn baking soda paste. Floss saful wan . Klin di denchɔ dɛn ɛvride.
• Rins yu mɔt: Rinse yu mɔt wit sɔl wata ɔ sɔl ɛn baking soda fayv to siks tɛm insay di de. Dis na di we we saful ɛn we go wok fayn fɔ klin di mɔt sos ɛn kil di smɔl smɔl smɔl smɔl smɔl smɔl smɔl smɔl smɔl smɔl smɔl smɔl smɔl smɔl smɔl smɔl smɔl smɔl smɔl smɔl smɔl smɔl smɔl smɔl smɔl smɔl smɔl smɔl smɔl smɔl smɔl smɔl smɔl smɔl smɔl smɔl smɔl. Yu kin yuz bak antiseptik we nɔ gɛt rɔm fɔ was yu mɔt.
• Di it: Di it we yu de it fɔ bi bland ɛn nɔ gɛt bɔku spays . Nɔ it it dɛn we gɛt asid, spaysi ɛn kranch. Nɔ it shuga ɛn rɔm. dis kin pwεl di mεmbran εn mek baktri dεm εn fכn dεm gro. Protein shake na gud tin fɔ mek yu gɛt mɔ it ɛn wata.
• Hydration: Yu kin nid fɔ drink mɔ wata fɔ kɔmpɛns yu mɔt we dɔn dray ɛn we di wata we de na yu dijestiv trakt dɔn go dɔŋ. Yu kin tray fɔ yuz atifishal saliva prodak we gɛt ɛnzaym lɛk Oral Balance®. Sɔm pipul dɛn kin si se we dɛn de sok ays chips, dat kin ɛp fɔ mek dɛn mɔt wet ɛn mek dɛn kol. Yu kin want bak fɔ protɛkt yu lip bay we yu de put lip balm.

Fɔ trit kɔmplikeshɔn dɛn

If yu nɔ gɛt bɛtɛ wata na yu bɔdi, yu nɔ de it fayn, ɔ yu gɛt di sik, yu kin nid:

• Di nyutrishɔn we de na di bɔdi
• Gi salin (IV fluid) .
• Antibayɔtiks

Wetin a fɔ it ɛn drink te di mucositis wɛl?

Gud tin dɛn fɔ it:

• Fɔd dɛn we gɛt bɔku prɔtin
• Nyutrishɔnal shek dɛn
• Sɔft it dɛn
• Popsikul dɛn we nɔ gɛt shuga

Tin dɛn we yu nɔ fɔ it:

• Fɔd dɛn we gɛt spays
• Fɔd dɛn we gɛt asid
• Fɔd dɛn we gɛt gris ɔ we dɛn dɔn frɛsh
• Fɔ it dɛn we gɛt bɔku shuga

Gud tin dɛn fɔ drink:

• Chamomile ti we dɛn kin mek
• Bɔku bɔku wata

Tin dɛn we nɔ fayn fɔ drink:

• Drink dɛn we gɛt kabon
• Rum

Yu tink se dɛn kin ebul fɔ avɔyd Mucositis?

Naw, nɔto bɔku tin wi kin du fɔ mek wi nɔ gɛt mucositis frɔm kansa tritmɛnt, bɔt dɔktɔ dɛn de du risach bɔt am. Naw dɛn de tɛst bɔrku mɛrɛsin wae kin ɛp fɔ ridyus de kayn sik ɛn aw kin te fɔ sɔm pipul dɛm. Sɔm pan dɛn na:

• Krayotɛrapi: If yu sok ays kiub bifo ɛn di tɛm we yu de tek di tritmɛnt fɔ di kemotɛrapi, dat kin ɛp fɔ protɛkt yusɛf frɔm ɔral mucositis.
• Palifermin: dis na sεntetik fכm fכ wan tin we wi bכdi de mek we dεn kכl kεratinosayt growth fכktכ (KGF). KGF de wok fכ protεkt εn ripa di sεl dεm na di mכt εn di dijestiv trakt. Dɛn dɔn sho se i kin ɛp fɔ ridyus di kayn we aw di mucositis kin tranga ɛn di tɛm we i kin tek pan pipul dɛn we gɛt blɔd kansa ɛn di wan dɛn we dɔn gɛt bon mɛrɔ ɔ stem sɛl transplant.
• di ejen dεm we dεn kin yuz fכ tכpik: dεn sho se Gelclair® εn Zilactin® de ridyus di mכkus we de na di כral bay we dεn de kכt εn protεkt di mכkus bifo dεn tek di rεdyushכn tεrapi.
• Amifostine: Dis mεdikeshכn kin ridyus di siriכs כral mכkusaytis pan pipul dεm we de du rεdyushכn tεrapi to dεn ed εn nεk. Bɔt, nɔs kin bi wan sayd ɛfɛkt.

If a gɛt dis sik, wetin a fɔ ɛkspɛkt?

Dis go ɔltɛm go insɛf afta yu dɔn dɔn yu kansa tritmɛnt, bɔt i kin tek tu to siks wik. Yu kin nid fɔ tek mɛrɛsin wae yu dɔktɔ gi yu fɔ mɛn yu pen fɔ ɛp yu fɔ bia wit dis tɛm. If yu tek kia ɔf yu mɔt mɔ ɛn kip am klin fɔ mek yu nɔ gɛt di sik, dat kin ɛp am fɔ wɛl kwik kwik wan. If yu gɛt infekshɔn ɔ i nɔ izi fɔ yu fɔ it ɔ drink, mek shɔ se yu go to dɔktɔ.

Ustɛm a fɔ go to mi dɔktɔ?

If yu notis dɛn sayn ya, go to dɔktɔ wantɛm wantɛm:

• We di fכs simptom dεm fכ mכkusayz de sho.
• If yu gɛt sayn dɛn we de sho se yu gɛt infekshɔn, lɛk fiva .
• If i nɔ izi fɔ yu fɔ it ɛn drink .
• If yu lɔs yu wet .
• If yu gɛt dayarɛa we nɔ de dɔn .
• If bɔku tɛm yu kin gɛt blɔd na yu mɔt ɔ yu stɔl.

Mucositis na wan pan di sayd ɛfɛkt dɛm wae kin kam wae pɔrsin gɛt kansa tritmɛnt. Aw e tranga kin dipen pan bɔrku tin, lɛk yu jenɛral wɛl bɔdi, di kayn tritmɛnt wae yu kin gɛt, ɛn aw yu kin kia fɔ yusɛf fayn fayn wan afta yu dɔn gɛt tritmɛnt.

Fɔ dɔn, mɛmba dis (Take-Home Message) .

Mucositis na fɔ sɔm tɛm, bɔt i nɔr nid fɔ bi lod, ɛn ɛp de. Di fɔs wik afta yu dɔn gɛt kansa tritmɛnt rili impɔtant fɔ mek yu wɛl. Rial risk de fɔ mek pɔsin nɔ it fayn ɔ fɔ gɛt infɛkshɔn insay dis tɛm. Ɔl tu fɔ kia fɔ yusɛf ɛn fɔ kia fɔ yu mɛrɛsin impɔtant we yu gɛt mucositis. Nɔr frayd fɔ tɔk to yu dɔktɔ ɛn gɛt di ɛp we yu nid. Nɔto yu wan de!

` Mucositis, kansa tritmɛnt, mɔt so, bɛlɛ inflamɛns, kemotɛrapi sayd ifɛkt, redyushɔn tritmɛnt sayd ifɛkt, ɔral kia