Yu bɔdi in difens dɛn smɔl? Lɛ wi tɔk bɔt nyutropenia!

Yu kin sik bɔku tɛm? Ɔ dɔktɔ dɔn ɛva luk yu blɔd tɛst ɛn se, "Yu wayt blɔd sɛl dɛn dɔn smɔl?" Sɔntɛm yu gɛt fiva, yu kin fil wik smɔl, bɔt yu nɔ ebul fɔ no wetin mek. Sɔmtɛm lɛk dis, i kin rili impɔtant fɔ mek yu no bɔt dis sik we dɛn kɔl nyutropenia, we wi de tɔk bɔt tide. Nɔ wɔri, lɛ wi ɛksplen am simpul wan.

Wetin na nyutropenia? I rili simpul!

Fɔ tɔk am simpul wan, nyutropenia na wan sik we yu blɔd gɛt wan kayn wayt blɔd sɛl we dɛn kɔl nyutrofil we smɔl pas di nɔmal. Tink bɔt dɛn nyutrofil ya as polisman dɛn we dɛn tren spɛshal wan insay wi bɔdi. Na dɛn wan ya de fɛt di jem dɛn lɛk baktri ɛn vayrɔs we de kam insay wi bɔdi ɛn protɛkt wi frɔm sik.

Dɛn kin mek dɛn sojaman dɛn ya we dɛn kɔl nyutrofil mɔ na wan faktri we de insay wi bon mɛro. So, we di nכmba fכ dεn nyutrofil dεm ya dכn, di ebul we wi bכdi fכ fכt di jεm dεm de dכn bak. Dat min se di chans fɔ gɛt infɛkshɔn kin bɔku pasmak. Sɔntɛnde, ivin baktri dɛm wae nɔrmal nɔr kin kɔz bɔrku trɔbul to pɔrsin wae gɛt wɛl bɔdi, lɛk di wan dɛm wae de na wi mɔt ɔr intestinal, kin mek pɔrsin gɛt siriɔs sik. Yu ɔndastand?

Wetin di nכmal lεvεl fכ di nyutrofil dεm fכ bi?

Dɛn kin sheb nyutropenia akɔdin to di nɔmba fɔ di nyutrofil dɛn we de na wan blɔd sɛmpul. Dɛn kin gri se big pɔsin fɔ gɛt at le 1,500 nyutrofil pan wan maykrolit blɔd. (Sɔm pipul dɛn kin tek dis limit as 1,800). Na dis na aw i kin brok dɔŋ:

• Mild nyutropenia: bitwin 1,000 – 1,500 nyutrofil dεm.
• mכdarεt nyutropenia: bitwin 500 – 1,000 nyutrofil dεm.
• Sivεr nyutropenia: I nɔ rich 500 nyutrofil.

Dis kכndyushכn kin bi fכ sכm tεm (akyu) כ lכng tεm (krכnik). I kin bi bak we dɛn bɔn am ɔ we pɔsin gɛt am.

Udat kin gɛt nyutropenia mɔ?

Sɔntɛnde, nyutropenia kin kam bikɔs ɔf infekshɔn. Bɔt bɔku tɛm dɛn kin si am as sayd ɛfɛkt we pɔsin kin gɛt we i de mɛn kansa, mɔ di kemotɛrapi. Risach pipul dɛm se te to 50% pan di pipul dɛm wae de gɛt kemotɛrapi kin gɛt nyutropenia.

כda kayn de we dεn kכl `Benign Ethnic Neutropenia (BEN).` Dis na wan kכndyushכn we dεn kin bכn pikin, we kin de fכ lכng tεm. I kin bɔku pan pipul dɛn we kɔmɔt na Afrika, Midul Ist, ɛn Wɛst Indian. Dɛn pipul ya gɛt nyutrofil kɔnt we nɔ rich 1,500, bɔt dɛn nɔ de pan big risk fɔ gɛt infɛkshɔn.

Aw nyutropenia kin afɛkt mi bɔdi?

di ifekt dεm we nyutropenia kin gεt kin difrεn dipכnt pan yu nyutrofil kכnt. Pɔsin wae gɛt mild nyutropenia nɔr kin gɛt ɛni sayn. Bɔku tɛm, dɛn kin no am bay we dɛn de du blɔd tɛst fɔ ɔda sik. Bɔt if yu gɛt mɔdaret to siriɔs nyutropenia, yu de pan bɔku bɔku risk fɔ gɛt infɛkshɔn. Siriv nyutropenia kin mek yu layf de pan denja if yu nɔ trit yu fayn. Dis na wae mek e fayn fɔ no bɔt dis sik.

Wetin mek nyutropenia kin apin? Wetin na di tin dɛn we kin mek i apin?

Nyutropenia kin bi bikɔs ɔf tri men tin dɛn:

1. Yu bon mכro nכ de mek inof nyutrofil.

2. di rεpid brεk dכwn (dεstrukshכn) fכ nyutrofil dεm we dεn de prodyuz.

3. Ɔ, fɔ pwɛl di nyutrofil dɛn we dɔn fɔm.

Na sɔm pan di rizin dɛn we mek:

• di jεnεtik kכndishכn dεm: sכmtεm dis kכndyushכn kin kכmכt frכm mama εn papa to pikin dεm tru di jin dεm. Benign Ethnic Neutropenia (BEN), Cyclic neutropenia, ɛn Severe congenital neutropenia na sɔm pan di kayn dɛn we kin kam bikɔs ɔf dɛn kayn jɛnɛtik kɔz ya.
• Infεkshכn: Nyutropenia kin kכz bak bay vayral, baktri, εn parasayt infεkshכn. Sɔm ɛgzampul dɛn na HIV, epataytis, TB, sɛpsis (we kin gɛt bad bad sik na di blɔd), ɛn Laym sik.
• Kansa: Kansa lɛk lukimiya, limfoma, ɛn ɔda sik dɛn we gɛt fɔ du wit di blɔd ɔ bon mɛrɔ kin mek di bɔdi nɔ ebul fɔ mek di wayt blɔd sɛl dɛn we gɛt wɛlbɔdi we i nid, ɛn dis kin mek i gɛt nyutropenia.
• Mɛrɛsin: Di tritmɛnt fɔ kansa, lɛk kemotɛrapi ɛn redyushɔn tɛrapi, kin pwɛl di nyutrofil ɛn di bon mɛro we de mek dɛn. Dɔn bak, sɔm mɛrɛsin fɔ ɔda tin dɛn we nɔ gɛt kansa kin mek di nyutrofil lɛvɛl go dɔŋ as sayd ɛfɛkt.
• Di tin dɛn we yu nɔ de it: Nyutropenia kin apin if di bɔdi nɔ gɛt inof vaytamɛn ɛn minral, lɛk vaytamɛn B12, folate, ɔ kɔpa.
• כtoimyun dεfisiεns: Dis na we wi כwn imyun sistεm nכ de כndastand wi yon imyun sistεm εn mek antibodi dεm we de pwεl nyutrofil dεm we gεt hεlty. I tan lɛk se wi yon ami de atak dɛnsɛf. Kron sik, lupus, ɛn rεumatoid at at na sɔm pan dɛn sik ya.

sכmtεm wan kכndyushכn de we dεn kכl `Chronic idiopathic neutropenia`. Dat min se, nyutropenia de, bɔt dɛn nɔ ebul fɔ fɛn di rayt tin we mek i apin .

Wetin mek di tritmɛnt fɔ kansa kin mek pɔsin gɛt nyutropenia?

Kansa tritmɛnt lɛk kemotɛrapi na rili pawaful mɛrɛsin. Dɛn kin kil di kansa sɛl dɛn. Bɔt dɛn kin pwɛl di sɛl dɛn bak we gɛt wɛlbɔdi ɛn we kin sheb kwik kwik wan. wi nyutrofil dεm εn di bon mכro sεl dεm we de mek dεn tu na sεl dεm we de sheb kwik kwik wan. Na dat mek nyutropenia kin apin we dɛn de tek kimotɛrapi. di nyutrofil lεvεl dεm kin dכn mכst insay di fכs tu wik dεm we dεn trit am. Afta dat, dɛn kin bɔku bak smɔl smɔl.

I rili impɔtant fɔ tek ɛkstra step fɔ protɛkt yusɛf frɔm infɛkshɔn insay dis tɛm, bikɔs dis na di tɛm we di bɔdi in difɛns kin wik pasmak.

Wetin na di sayn dɛm fɔ nyutropenia?

Nyutropenia insɛf nɔ gɛt ɛni patikyula sayn. Bɔt if yu gɛt infɛkshɔn bikɔs ɔf nyutropenia, yu kin gɛt sayn dɛn fɔ dɛn infɛkshɔn dɛn de. Infekshɔn ɔltɛm kin bi sayn bak fɔ nyutropenia. Na sɔm pan di sayn dɛm wae de sho se yu gɛt dis sik:

• Fiva (especially wan sik we dɛn kɔl febrile neutropenia) .
• Taya
• Trot we de at (Pharyngitis) .
• Di limf no dɛm we dɔn swel
• Ɔlsa na di mɔt ɔ rawnd di an
• Pen, swel, ɛn rɛd rɛd na di say we di sik de
• Indigestion, dayarɛa
• Urinary symptoms, lɛk fɔ bɔn we yu de pis ɛn fɔ pis ɔltɛm

If yu gɛt smɔl nyutropenia, yu kin gɛt inof nyutrofil na yu bɔdi fɔ fɛt infɛkshɔn. If na so i bi, yu nɔ go gɛt ɛni sik.

Aw dɛn kin no if pɔsin gɛt nyutropenia?

di men εn simpul tεst fכ no dis na komplit blכd kכnt (CBC) wit difrεns . If yu de du tritmɛnt lɛk kemotɛrapi, yu dɔktɔ go du dis tɛst ɔltɛm fɔ wach yu nyutrofil lɛvɛl.

If yu dɔktɔ nɔ shɔ wetin de mek yu gɛt nyutropenia, i kin ɔda fɔ mek dɛn du mɔ tɛst. Fɔ ɛgzampul, dɛn kin tek wan sɛmpul pan yu bon mɛro ɛn chɛk am wit maykroskɔp. dis tεst kin no if nyutrofil dεm de prodyuz fayn fayn wan na yu bon mכro, כ if dεn de pwεl afta dεn dכn prodyuz dεm. Dis infɔmeshɔn kin ɛp yu dɔktɔ fɔ kɔnfirm di sik.

Wetin na di tritmɛnt fɔ nyutropenia?

Sɔm kayn nyutropenia kin nɔ nid tritmɛnt. Ɔda tritmɛnt opshɔn dɛn de dipen pan di tin we mek yu nɔ gɛt bɛtɛ nyutrofil lɛvɛl.

Dɛn kin du dɛn tin ya as tritmɛnt:

• Antibayɔtik: If yu gɛt fiva nyutropenia wit fiva, antibayɔtik kin sev yu layf. Bɔku tɛm dɛn go admit yu na ɔspitul ɛn gi yu antibayɔtik, lɛk salin, insay yu bɛlɛ. Insay dis tɛm, dɛn go du tɛst fɔ no wetin mek di sik kam.
• Kɔtikosterɔyd: If yu gɛt nyutropenia we kɔmɔt frɔm wan ɔtoimyun kɔndishɔn, yu dɔktɔ kin gi yu wan mɛrɛsin we dɛn kɔl kɔtikosterɔyd. Dɛn mɛrɛsin ya kin mek yu imyun sistɛm nɔ wok fayn, ɛn dis kin pwɛl yu nyutrofil dɛn.
• Granulocyte colony-stimulating factor (G-CSF): Yu dɔktɔ kin gi yu mɛrɛsin dɛn bak we go mek yu bon mɛrɔ mek wayt blɔd sɛl dɛn. If yu de tek kemotɛrapi, dɛn kin gi yu dis G-CSF injɛkshɔn.

If dɛn no se na wan mɛrɛsin we yu de tek de mek nyutropenia, yu dɔktɔ go tɛl yu fɔ stɔp fɔ tek da mɛrɛsin de ɔ chenj di doz.

Yu tink se dɛn kin mek nyutropenia nɔ apin?

Wi nɔ kin ebul fɔ stɔp di kayn nyutropenia we dɛn bɔn wit. Bɔt if yu de tek kemotɛrapi, if yu dɔktɔ sɔprayz se yu nyutrofil lɛvɛl nɔ bɔku, i kin delay di nɛks raun fɔ kemotɛrapi ɔ i kin ridyus di doz. Dɛn kin se bak fɔ gi yu G-CSF injɛkshɔn fɔ mek yu gɛt mɔ wayt blɔd sɛl.

Aw a go protɛkt misɛf frɔm infɛkshɔn if a gɛt nyutropenia?

If yu no se yu nyutrofil dɛn nɔ bɔku, bɔku tin dɛn de we yu kin du fɔ protɛkt yusɛf frɔm infɛkshɔn. Dɛn tin ya rili impɔtant fɔ mɛmba.

• Was yu an ɔltɛm wit sop ɔ yuz han sɛnitayza we gɛt rɔm.
• Inklud flu ɛn Covid-19 `(COVID-19)`Gɛt ɔl yu vaysin dɛn di rayt tɛm.
• Nɔ de fa frɔm pipul dɛn we sik ɛn na say dɛn we pipul dɛn kin gɛda usay yu go mit pɔsin we sik.
• Tek tɛm wit skrach, kɔt, ɛn wund (inklud tatu ɛn bɔdi piercing). Trit ɛnitin we dɔn pwɛl na yu skin wantɛm wantɛm.
• Wash frut ɛn vɛjitebul dɛn fayn fayn wan, separet mit ɛn fish frɔm ɔda it dɛn, ɛn pripia it na klin kichin, kuk am fayn. Dis we ya, yu kin mek di jem nɔ skata.
• Nɔ sheb tin dɛn fɔ it, kɔp, ɔ it ɛn drink wit ɔda pipul dɛn.
• Nɔ sheb tin dɛn lɛk tawɛl, reza, ɛn tut brɔsh wit ɔda pipul dɛn.
• If yu de wok na gadin, wɛr glɔv.
• Nɔ pul di dɔti we yu kin yuz fɔ mɛn yu animal ɛn chenj di dayapɛt we yu jɔs bɔn as yu ebul (if yu fɔ du am, wɛr glɔv ɛn was yu an fayn fayn wan afta yu dɔn).
• Nɔ yuz lek, pɔnd, riva, ɛn ɔt tub.
• Yuz di mɛrɛsin dɛn jɔs lɛk aw yu dɔktɔ tɛl yu fɔ mek yu nɔ gɛt di sik.

Bɔku pan dɛn advays ya na tin dɛn we wi kin du fɔ gɛt wɛlbɔdi. Bɔt if yu gɛt nyutropenia, yu nid fɔ tek tɛm mɔ. Aks yu dɔktɔ wetin ɔda tin yu kin du fɔ protɛkt yusɛf frɔm infɛkshɔn, i go dipen pan aw yu de liv yu layf ɛn aw yu gɛt wɛlbɔdi.

Wetin na di prɔgnosis fɔ pipul dɛm wae gɛt nyutropenia? (Prɔgnosis) .

Nyutropenia kin trit, so de luk fɔ bɔrku pipul dɛn kin fayn. Di tin we impɔtant pas ɔl na fɔ mek yu nɔ gɛt di sik ɛn go to tritmɛnt kwik kwik wan (if yu sik).

Ustɛm a fɔ go to dɔktɔ?

If yu de tek kemotɛrapi ɔ yu gɛt ɔda sik we kin mek yu gɛt nyutropenia, go to dɔktɔ wantɛm if yu gɛt ɛni wan pan dɛn sik ya, ɔ kɔl yu dɔktɔ wantɛm wantɛm fɔ advays yu bɔt wetin fɔ du:

• Fiva we gɛt 100.4 digri F (38 digri sɛlshiɔs) ɔ pas dat.
• Swet ɔ shek shek bikɔs ɔf kol.
• I nɔ kin izi fɔ yu fɔ blo.
• Nasal kɔnjɛshɔn.
• Trot ɔ nɛk kin at we kin stif.
• Nyu kɔf ɔ kɔf we dɔn de we dɔn wɔs.
• Dayarɛa ɛn/ɔ vɔmit.
• Dischaj na di vagina ɔ i de it.
• Pen, rɛd, ɔ swel ɛnisay na di bɔdi.
• Chenj we yu de pis (pen, bɔn, nid fɔ pis ɔltɛm).
• Nyu biginin fɔ pen, mɔ na di bɛlɛ ɔ rɛktum.
• Fɔ fil se yu kɔnfyus ɔ yu maynd difrɛn frɔm aw yu kin fil.
• Fɔ fil se yu taya pasmak ɔ yu nɔ gɛt wɛlbɔdi.

Aw yu kin gɛt nyutropenia de dipen pan wetin mek yu nyutrofil lɛvɛl dɛn go dɔŋ. If yu lɛvɛl smɔl bikɔs ɔf wan infekshɔn we yu jɔs gɛt, i go mɔs bi se dɛn go kam bak to nɔmal as yu bɔdi de wɛl. If yu nyutropenia na bikɔs yu gɛt lɔng tɛm sik ɔ kemotɛrapi, yu dɔktɔ go de wach yu nyutrofil lɛvɛl ɔltɛm fɔ mek yu nɔ gɛt prɔblɛm dɛn frɔm infɛkshɔn. Aks yu dɔktɔ if yu nyutropenia nid fɔ de du mɛrɛsin tɛst ɔltɛm ɛn mɛrɛsin fɔ mek yu nɔ gɛt di sik.

Fɔ dɔn, tin dɛn fɔ mɛmba (Take-Home Message) .

Nyutropenia na wan sik we di bɔdi in wayt blɔd sɛl dɛn we dɛn kɔl nyutrofil, nɔ kin bɔku. Dis kin mek di risk fɔ gɛt di sik bɔku. Dis sik kin mɔna pipul dɛm wae de gɛt kansa tritmɛnt lɛk kimotɛrapi.

Na nɔrtin fɔ wɔri bɔt, tritmɛnt dɛn de fɔ dis. Di tin we impɔtant pas ɔl na:

• Fɔ fala yu dɔktɔ in instrɔkshɔn dɛn di rayt we.
• Fɔ tek ɛvri step fɔ protɛkt yusɛf frɔm infekshɔn.
• If yu notis ɛni sayn fɔ se yu gɛt di sik, lɛk fiva , go to dɔktɔ wantɛm wantɛm.

If yu no dis ɛn tek tɛm, yu kin gɛt wɛl bɔdi ivin wit nyutropenia. Nɔ ɛva shem fɔ tɔk to yu dɔktɔ bɔt ɛni kwɛstyɔn ɔ tin we de mɔna yu.

` Nyutropenia, nyutrofil, wayt blɔd sɛl, imuniti, infɛkshɔn, kansa, kemotɛrapi