Yu nɔ gɛt ɔl di tri kayn blɔd sɛl dɛn? Lɛ wi tɔk bɔt pansitɔpenia!

Sɔntɛnde, yu kin fil taya ɔltɛm? Ɔ yu kin sik pan smɔl tin, ɔ yu notis brus ɔlsay na yu bɔdi? Dɛn tin ya kin bi bikɔs ɔf sɔm chenj dɛn na yu blɔd. Tide wi go tɔk bɔt wan sik we kin apin na dɛn kayn tɛm ya, we dɔktɔ dɛn kin kɔl "pancytopenia". Nɔ wɔri, wi go tɔk bɔt dis simpul wan.

Wetin na pansaytopenia?

Fɔ tɔk am simpul wan, pansaytopenia na wan sik we ɔl di tri men kayn blɔd sɛl dɛn na wi bɔdi – rɛd blɔd sɛl, wayt blɔd sɛl, ɛn pletlɛt – de smɔl pas aw i nɔmal. Tink bɔt am lɛk big faktri. Difrɛn wokman dɛn de na dis faktri fɔ difrɛn wok dɛn. Na so dɛn blɔd sɛl dɛn ya de du. Ɛni kayn we gɛt wan patikyula wok.

Naw luk wetin kin apin we dɛn kayn sɛl ya dɔn go dɔŋ:

• Rɛd blɔd sɛl dɛn we de go dɔŋ: Na dɛn sɛl ya de kɛr ɔksijɛn ɔlsay na wi bɔdi. Dɛn sɛl dɛn ya gɛt wan spɛshal prɔtin we dɛn kɔl ɛmoglobin . Na dat de ol di ɔksijɛn. So, we di rεd bכdi sεl dεm כ hεmoglobin dכn dכn, wi kin kכl am "anemia" כ "blכd dεficiency."
• Wait blɔd sɛl dɛn we dɛn kin kɔnt: Wait blɔd sɛl dɛn ɔ lukosayt dɛn tan lɛk di bɔdi in difens sɛl dɛn. Dɛn kin fɛt jem ɛn protɛkt wi frɔm sik. Pan dɛn wayt sɛl ya, di wan we bɔku pas ɔl na nyutrofil . We di wayt blɔd sɛl dɛn de dɔŋ, dɛn kin kɔl am lukɔpania . we di nyutrofil dεm dכn dכn dεn kכl am bak nyutropenia .
• di pletlet dεm we de kכmכt sכmtεm sכmtεm: di pletlet dεm na sכm sכm sכm sεl dεm. Bɔt dɛn de du big wok. We wi kɔt, dɛn pletlɛt ya kin ɛp fɔ stɔp di blɔd. Dɛn rili impɔtant fɔ mek blɔd klɔt. So, we di pletlɛt dɛn nɔ bɔku, dɛn kin kɔl di sik trombocytopenia .

If yu gɛt pancytopenia, yu kin gɛt sɔm sayn dɛm wae kin kam wit wan, sɔm, ɔr ɔl dɛn sik ya, i kin dipen pan aw yu blɔd sɛl dɛn smɔl.

Aw kɔmɔn tin na pansaytopenia?

Infakt, di sik we dɛn kɔl pancytopenia nɔ kin bɔku lɛk aw yu kin tink. Bikɔs bɔku tin dɛn de we kin mek pɔsin gɛt dis sik, i nɔ kin izi fɔ tɔk klia wan ɔmɔs pipul dɛn kin gɛt am.

Wetin na di sayn dɛm fɔ pansaytopenia?

Sɔntɛnde, pancytopenia kin rili smɔl. Yu nɔ go notis ɛni big big sayn. Sɔntɛnde, dɔktɔ go fɛn am we dɛn de du rutin blɔd wok. Bɔt sɔm tɛm dɛn de we de sik kin rili bad ɛn kin mek pɔsin in layf de pan denja. If na so i bi, yu fɔ go to tritmɛnt wantɛm wantɛm.

Naw lɛ wi si wetin na di difrɛn sayn dɛm we dɛn kayn blɔd sɛl ya de go dɔŋ.

Di sayn dɛn we de sho se di rɛd blɔd sɛl dɛn nɔ de bɔku (anemia) .

If yu nɔ gɛt inof rɛd blɔd sɛl, yu bɔdi in ɔda ɔgan ɛn tisu dɛn nɔ go gɛt inof ɔksijɛn. Yu kin gɛt sɔm kayn sik lɛk:

• Fɔ fil taya ɔltɛm (Fatigue): Na filin fɔ taya ɛn nɔ want fɔ du ɛnitin.
• I nɔ izi fɔ blo (dyspnea): Fɔ fil shɔt fɔ blo ivin if yu tray smɔl.
• Fɔ fil se yu gɛt diziz.
• Ed de at.
• Aritmia na wae pɔrsin kin fil wae de at de bit kwik kwik wan ɔr nɔr de bit ɔltɛm.
• Pale skin ɔ kol, swet filin.

Di sayn dɛn we de sho se di wayt blɔd sɛl dɛn nɔ de bɔku (lukopenia) .

We yu nɔ gɛt bɛtɛ wayt blɔd sɛl, di ebul we yu bɔdi ebul fɔ fɛt di sik kin go dɔŋ. Dis min se yu kin gɛt infɛkshɔn izi wan. Dɛn infɛkshɔn ya kin mek yu gɛt sɔm sayn dɛm lɛk:

• Fɔ fil taya ɔltɛm (Fatigue).
• Fiva ɛn kol kol.
• Trot we de at ɔ infekshɔn (farinjitis).
• Sɔl dɛn na yu mɔt.
• Fɔ kɔf bɔku bɔku wan.
• Rɔnbɛlɛ.
• I nɔ kin izi fɔ yu fɔ blo.
• Di limf no dɛm we dɔn swel.
• Pus we de drayn frɔm di kɔt dɛn.

Di sayn dɛn we de sho se di pletlɛt dɛn nɔ bɔku (thrombocytopenia) .

We yu pletlɛt dɛn smɔl, yu blɔd nɔ kin klot fayn. Dis kin mek tin dɛn lɛk:

• Fɔ gɛt brus na yu bɔdi frɔm ivin di smɔl tin.
• Blɔd we nɔ kin izi fɔ stɔp ɔ we kin te fɔ lɔng tɛm.
• Blɔd we de kɔmɔt pasmak we uman dɛn de gɛt mɔnt.
• Blɔd we de kɔmɔt wit stɔl, urine , ɔ vɔmit.
• Rɛd ɔ pepul spat dɛn na di skin (petechiae) – we fiba lɛk we yu gɛt rash. Sɔntɛnde, rɛd, pepul, ɔ brawn spat (purpura) kin apia bak.

Wetin kin mek dis sik wae gɛt pansaytopenia?

Pancytopenia kin kam bikɔs ɔf wan prɔblɛm we de na di prɔses fɔ mek blɔd sɛl dɛn na wi bon mɛro . Yu no se wi blɔd sɛl dɛn de kɔmɔt na di bon mɛro? Dɛn kɔl dis prɔses ɛmatopoɛsis . Dɛn sɛl ya kin kɔmɔt na di bon mɛro ɛn go insay wi blɔd jɔs afta dɛn dɔn machɔ.

So, pancytopenia kin apin if yu bon mכro nכ de prodyuz inof hεlty bכdi sεl dεm, כ if dεn blכd sεl dεm ya dכn pwεl tu kwik afta dεn dכn prodyuz dεm.

Bɔku tin dɛn de we kin mek dɛn blɔd sɛl ya nɔ mek dɛn ɔ pwɛl dɛn:

• Sik dɛn we gɛt fɔ du wit bon mɛrɔ:Sɔm sik dɛn de we kin mek di bon mɛro mek blɔd sɛl dɛn we nɔ fayn. Mɔs pan dɛn tin ya na `acquired` insay wi layf. Sɔm na `inherited`. Fɔ ɛgzampul:
• Aplastik anemia we dɛn kin gɛt
• Fankɔni anemia
• Daymɔnd-Blakfan anemia

• Kansa: We di kansa sɛl dɛn skata to di bon mɛro, dɛn kin ambɔg di blɔd sɛl dɛn we gɛt wɛlbɔdi. Sɔm kayn kansa wae kin mek pɔrsin gɛt pancytopenia na:
• Lukimiya
• Limfoma we dɛn kɔl Limfoma
• Bɔku bɔku mayloma
• Maylofibrosis we dɛn kɔl myelofibrosis
• Maylodysplastic sindrom dɛn we dɛn kin gɛt
• Spread of kansa frɔm ɔdasay to di bon mɛro (metastatic cancer) .

• Di it we yu nɔ gɛt bɛtɛ it ɛn we yu de drink rɔm: If yu bɔdi nɔ gɛt bɛtɛ tin fɔ it lɛk vaytamɛn B12 ɛn folate , i nɔ go ebul fɔ mek blɔd sɛl dɛn we gɛt wɛlbɔdi. Dɔn bak, fɔ drink tumɔs rɔm kin bi wan men tin we kin mek pɔsin gɛt pansaytopenia.

• Sik dɛm wae kin kam pan pɔrsin: Dis sik kin kam bak frɔm sɔm kayn vayrɔs dɛm. Ɛgzampul dɛn:
• Mononucleosis `(Mononukleosis - mono)`
• HIV (vayrɔs we de mek mɔtalman nɔ ebul fɔ fɛt di sik) .
• Epataytis C we dɛn kɔl C
• Parvovayrɔs B19 `(Parvovayrɔs B19)`
• Tubakulosis sik we dɛn kɔl Tuberculosis
• Malaria we pɔsin kin gɛt

• Autoimyun kondishכn dεm: Dis na we yu bכdi in כwn imyun sεl dεm de atak hεlty bכdi sεl dεm. Di sik dɛm wae kin kam wit ɔtoimyun wae kin mek pɔrsin gɛt pansaytopenia na:
• Lupus we gɛt di sik
• Rimatɔyd at at sik

• Drug tritmɛnt: Sɔm mɛrɛsin, mɔ di kemotɛrapi drɔgs fɔ kansa, kin mek di blɔd sɛl nɔ bɔku.

• If yu gɛt pɔyzin: Pɔyzin we de na di say we yu de liv lɛk bɛnzin ɛn asɛnik kin pwɛl yu blɔd sɛl dɛn. If yu gɛt raytin, dat kin mek yu blɔd sɛl dɛn nɔ bɔku bak.

• Splenik sikwɛstreshɔn: .Sɔm mɛrɛsin kin mek di blɔd sɛl dɛn gɛda na yu splin. Di sik dɛn we pɔsin kin gɛt we i de fɛt insɛf, sirosis na di liva, ɛn sɔm kansa kin mek pɔsin gɛt dis. we dis apin, di splin kin swεla εn i kin fil pen (splenomegaly).

Sɔntɛnde, dɔktɔ dɛn nɔ kin ebul fɔ fɛn di rayt tin we kin mek di blɔd sɛl dɛn de dɔŋ dis kayn we. Dɛn kɔl dis idiopatik pansaytopenia .

Udat de pan ay risk fɔ gɛt pancytopenia?

Ɛnibɔdi we gɛt di kɔndishɔn we wi bin dɔn tɔk bɔt kin gɛt pancytopenia. Bɔt if pɔsin na yu famili gɛt dis sik, ɔ if yu de tek kemotɛrapi we de afɛkt di we aw blɔd sɛl dɛn de mek, yu go gɛt dis sik.

Aw dɛn kin no se pɔsin gɛt pansaytopenia?

If yu kɔnt ɔl di blɔd (CBC) ɔltɛm, dat kin chɛk fɔ si if di blɔd sɛl dɛn nɔ bɔku. Dɛn valyu ya kin difrɛn smɔl dipen pan tin dɛm lɛk ej, rays, ɛn wɛl bɔdi.

Dis na di lεvεl dεm we dεn kin kכnsidr fכ lכw:

• Rɛd blɔd sɛl dɛn: Fɔ uman dɛn, i nɔ rich 4.2 milyɔn sɛl dɛn pan wan maykrolita blɔd ɔ i nɔ rich 12 gram (g) ɛmoglobin (fɔ wan dɛsilita). Fɔ man dɛn, i nɔ rich 4.7 milyɔn sɛl dɛn pan wan maykrolita blɔd ɔ i nɔ rich 13 gram ɛmoglobin (fɔ wan dɛsilita).
• Wait blɔd sɛl dɛn: I nɔ rich 4,000 wayt blɔd sɛl dɛn pan wan maykrolita blɔd, ɔ nyutrofil kɔnt we nɔ rich 1,800 pan wan maykrolita blɔd. Nyutrofil na di kayn wayt blɔd sɛl we bɔku pas ɔl, so dis kɔnt rili impɔtant.
• Plɛtlɛt dɛn: I nɔ rich 150,000 pletlɛt dɛn pan wan maykrolit blɔd.

Us ɔda tɛst dɛn de du fɔ no di rizin?

Wae yu dɔktɔ dɔn no se yu gɛt pancytopenia, dɛn kin du sɔm ɔda tɛst fɔ no wetin de mek yu gɛt am. Yu kin nid bak fɔ go to dɔktɔ we spɛshal pan blɔd sik dɛn (hematologist) .

Dɛn tɛst ya kin bi:

• Peripheral blood smear: Dis tɛst de luk yu blɔd sɛl dɛn ɔnda maykroskɔp. If ɛni sɛl de we nɔ gɛt shep, i kin gi wi no bɔt di tin we mek i apin.
• di tεst dεm fכ di vitamin B12 εn folate lεvεl dεm: Pancytopenia kin kכmכn bak fכ di it we dεn nכ de it. So we yu chɛk dɛn lɛvul ya, dat kin ɛp fɔ no if na dat mek yu gɛt am.
• Bone marrow aspiration and biopsy: Insay dis prosidur, dɔktɔ kin tek smɔl sampul pan yu bon marrow ɛn tɛst am fɔ si if ɛni sik de we kin mek pɔsin gɛt pancytopenia, lɛk kansa.

Dipen pan yu tɛst rizɔlt, mɛdikal histri, ɛn di sayn dɛm, yu dɔktɔ kin du tɛst dɛm lɛk dis bak fɔ luk fɔ ɔda tin dɛm wae de mek yu gɛt dis sik:

• Vayrɔs tɛst dɛn.
• Test fɔ si if pɔsin gɛt infɛkshɔn.
• Tεst fכ כtoimyun kכndishכn dεm.
• Tεst fכ jεnεtik mכtεshכn (chεnj dεm na yu DNA).

Aw dɛn kin trit pansaytopenia?

Di tritmɛnt de mɔ fɔ fɛn di ɔndalayn kɔz fɔ di sik, fɔ trit am, ɛn fɔ ridyus di sayn dɛm. Tritmɛnt dɛn de bak we kin mek yu blɔd sɛl dɛn bɔku dairekt wan. Dɛn tin ya na:

• Mɛrɛsin: Sɔm mɛrɛsin dɛn de we de mek di bon mɛrɔ wok ɛn ɛp am fɔ mek mɔ blɔd sɛl dɛn.
• Blɔd transfyushɔn: If yu blɔd sɛl nɔ bɔku ɛn i kin ambɔg yu wɛlbɔdi, dɛn kin gi yu rɛd blɔd sɛl ɔ pletlɛt.
• stεm sεl כ bon mכro transplant: dεn prosidכs dεm ya na fכ pul stεm sεl dεm we nכ de wok fayn (dεn na di bεs sεl dεm na di bon mכro we de mek bכdi sεl dεm) εn transplant stεm sεl dεm we gεt hεlty.

If yu nyutrofil lɛvɛl rili smɔl ɛn yu de pan big risk fɔ gɛt infɛkshɔn, dɛn kin gi yu bak bɔku bɔku antibayɔtik .

Wetin pɔsin we gɛt pancytopenia fɔ ɛkspɛkt?

Di chans fɔ mek yu wɛl dipen pan wetin mek di blɔd sɛl dɛn nɔ bɔku. Naw, no difinitiv data nɔ de bɔt di sakrifays we di tritmɛnt dɛn fɔ pansaytopenia gɛt. Bifo dat, di wan dɛn we de stɔdi bɔt dis kin luk aw di tritmɛnt dɛn kin wok fɔ di sik we de ɔnda dis sik.

Di impɔtant tin na dat as di tritmɛnt fɔ di ɔndalayn kɔndishɔn dɛn de impɔtant, di tin dɛn we kin apin to pipul dɛn we gɛt pansaytopenia kin bɛtɛ bak. So, e fayn fɔ tɔk to yu dɔktɔ bɔt dis. I kin tɛl yu di laytst risach infɔmeshɔn ɛn ɛksplen aw i kin afɛkt yu sik.

Yu tink se pansaytopenia na siriɔs sik?

Yɛs, i kin rili siriɔs. I dipen bak pan wetin de mek yu blɔd sɛl nɔ bɔku. If yu gɛt pancytopenia, yu dɔktɔ go luk fɔ di kɔz ɛn no aw i siriɔs.

Ustɛm a fɔ go na ɔspitul (ETU) kwik kwik wan?

Pancytopenia kin rili bad ɛn i kin mek pɔsin in layf de pan denja if dɛn nɔ trit am. If yu gɛt ɛni wan pan dɛn sik ya, go na imejensi rum (ETU) wantɛm wantɛm:

• If di fiva pas 101 digri F (38 digri sɛlshiɔs).
• If yu lɔs kɔnshɛns (blak ɔt).
• If yu gɛt siriɔs prɔblɛm fɔ blo.
• Kɔnfyushɔn we kin apin wantɛm wantɛm.
• If yu bigin fɔ gɛt nyu ed we de at.
• If blɔd de kɔmɔt bad bad wan.
• If yu gɛt pen na yu chɛst.
• If wan sik we dɛn kɔl seizure apin.

Pancytopenia kin afɛkt yu difrɛn we dɛn. I dipen pan aw yu blɔd sɛl dɛn smɔl ɛn wetin na di men tin we de mek yu blɔd. If yu blɔd sɛl dɛn de put yu pan denja fɔ gɛt anemia, infɛkshɔn, ɔ blɔd pasmak, fala yu dɔktɔ in instrɔkshɔn dɛn gud gud wan. Aks bak bɔt ɛni sayn we go sho se yu fɔ go to yu dɔktɔ.

Fɔ dɔn, tin dɛn fɔ mɛmba (Take-Home Message) .

So, yu go dɔn ɔndastand naw se pancytopenia na wan sik we ɔl tri wi blɔd sɛl dɛn, dat na rɛd sɛl dɛn, wayt sɛl dɛn, ɛn pletlɛt dɛn, kin ridyus wan tɛm. Bɔrku tin kin de fɔ dis, ɛn de sayn dɛm bak kin difrɛn.

De tin wae impɔtant pas ɔl na fɔ go to dɔktɔ if yu gɛt dɛn kayn sik ya. Dɔn i kin no wetin nɔ rayt ɛn bigin di tritmɛnt we yu nid. If yu kech am kwik, bɔku tɛm yu kin ebul fɔ manej dɛn tin ya fayn fayn wan. So, tek kia ɔf yu bɔdi, ɛn if yu notis ɛni ɔda tin, pe atɛnshɔn to am. Stay wit wɛlbɔdi!

` Pancytopenia, Pancytopenia, Blɔd sɛl dɛfisiɛns, Rɛd blɔd sɛl, Wayt blɔd sɛl, Plɛtlɛt, Bɔn mɛro, Anemia, Lukopenia, Thrombocytopenia