Lɛ wi lan gud gud wan bɔt di strenj sik dɛn we kin kam wit kansa (Paraneoplastic Syndromes)!

Yu dɔn ɛva yɛri bɔt pɔrsin wae gɛt kansa kin gɛt sɔm kayn sik wae nɔr kin kɔmɔt frɔm di kansa insɛf, bɔt na ɔda sik kin kam wit am? I tan lɛk se di kansa de na wan pat na di bɔdi, bɔt di tin dɛn we i kin du de go ɔda pat dɛn. Na dat wi kin kɔl (Paraneoplastic Syndromes) . Dis kin tan lɛk se i kɔmplikt smɔl, bɔt lɛ wi tɔk bɔt wetin de apin. Nɔr frayd, i rili impɔtant fɔ no bɔt dis.

Wetin na paraneoplastic syndrome?

Fɔ tɔk am simpul wan, we yu gɛt kansa, wi kin kɔl am Paraneoplastic Syndrome , we na we ɔda sayn dɛn kin apia na di bɔdi we nɔ gɛt di kansa sɛl dɛn dairekt wan. Imajin, kansa de na di bɔdi, bɔt sɔm ɔmon ɔ prɔtin dɛn we i de pul kin mek wan patikyula sistɛm na di bɔdi bigin fɔ wok difrɛn we. Ɔ, sɔntɛnde wi imyun sistɛm , pan ɔl we i de tray fɔ pwɛl di kansa sɛl dɛn, i kin mistek atak gud sɛl dɛn bak. Wi kin kɔl dis ɔtoimyun rispɔns . Dɛn sayn ya kin apin bak pan dɛn kayn tin ya.

Paraneoplastic syndrome kin afekt plεnti difrεn sistεm dεm na di bכdi. Fɔ ɛgzampul, yu nervɔs sistɛm , ɛndokrin sistɛm (di sistɛm we de mek ɔmon), kidni , bon , jɔyn , skin, ɛn blɔd ɔl kin afɛkt.

Bɔku tɛm, di sayn dɛm fɔ wan pan dɛn tin ya (Paraneoplastic Syndromes) na di fɔs sayn dɛm fɔ gɛt kansa. So, i rili impɔtant fɔ mek wi no bɔt dis.

Udat dɛn kin gɛt dis sik pas ɔlman? (Udat kin afɛkt di sik we dɛn kɔl paraneoplastic syndromes?)

Paraneoplastic syndromes kin mɔs pan pipul dɛm wae dɔn ol ɛn ol pipul dɛm, mɔr lɛk di wan dɛm wae gɛt sik dɛm lɛk lɔng kansa , limfatik kansa , ovarian kansa , ɔ brɔst kansa . Di sem tin wae kin mek pɔrsin gɛt kansa kin mek pɔrsin gɛt dɛn sik ya bak.

Aw dɛn tin ya kɔmɔn? (Aw kɔmɔn tin dɛn we gɛt fɔ du wit paraneoplastic syndromes?)

Paraneoplastic Syndrome kin apin bitwin 8% ɛn 20% pan pipul dɛm wae gɛt kansa. Dis min se nɔto ɔl di wan dɛn we gɛt kansa kin gɛt dɛn, bɔt dɛn kin afɛkt bɔku bɔku wan.

Us kansa wae gɛt fɔ du wit paraneoplastic syndromes?

Ɛnibɔdi we gɛt kansa tumbu (Paraneoplastic Syndrome) .Pan ɔl we ɛni wan kin apin, bɔku kayn kansa de we kin gɛt fɔ du wit dɛn tin ya:

• Brɔst kansa
• Bɛlɛ kansa
• Lukimiya
• Limfoma we dɛn kɔl Limfoma
• Lכng kansa (especially sכm sכm sεl lכng kεnsar) .
• Kansa na ovarian
• Kansa na di pankrias
• Prɔstat kansa
• Kidni kansa
• Testikul kansa

Wetin kin mek yu gɛt paraneoplastic syndrome?

Wi dɔn tɔk se tu men rizin dɛn de fɔ dis.

1. Sɔbstans dɛn we di kansa sɛl dɛn kin pul: Sɔm kansa dɛn kin pul ɔmon ɛn prɔtin dɛn . Dɛn tin ya kin mek sɔm ɔgan dɛn na di bɔdi nɔ de wok fayn. If dɛn nɔ trit dis, i kin ivin mek i pwɛl sote go.

2. Imyun sistεm nכ de wok fayn: Wi bכdi in imyun sistεm de fכ protεkt wi frכm sik dεm. Dis sistɛm de mek tin dɛn we dɛn kɔl antibodi . Dɛn antibodi dɛm ya kin no ɛn pwɛl di sɛl dɛm we nɔrmal, lɛk di kansa sɛl dɛm. bכt sכmtεm, dεn signal dεm ya kin miks εn di antibodi dεm kin bigin fכ atak hεlty sεl dεm bak. Na da tɛm de di sayn dɛm fɔ wan (Paraneoplastic Syndrome) de sho.

Wetin na di sayn dɛm fɔ paraneoplastic syndromes?

De sayn dɛm wae de sho pan dis kin difrɛn frɔm pɔrsin to ɔda pɔrsin. I dipen pan us sistɛm na di bɔdi de afɛkt. I sɔprayz fɔ no se pan pas 60% pan di kes dɛm, di sayn dɛm fɔ dis sik kin apin bifo dɛn ivin no di kansa. So, if dɛn no dɛn sayn ya kwik kwik wan, dɛn kin no di kansa ɛn trit am kwik kwik wan. Dɔn di chans fɔ mek di tritmɛnt go bifo kin bɔku.

Di kɔmɔn sayn dɛm

Dis na sɔm pan de sik wae kin kam pan pɔrsin:

• Fiva
• I nɔ kin want fɔ it ɛn i nɔ kin gɛt bɔku bɔku bɔdi
• Nayt swet dɛn

We di nervɔs sistɛm kin afɛkt

If yu sεntri nεv sεstem (dat na yu bren εn spεnal kכd) εn pεrifεral nεv sεstem (di nεv dεm we de kכmכt na di bren εn spεnal kכd) afekt, yu kin gεt sכmtεm dεm lεk:

• Diziz we pɔsin kin gɛt
• Dabl vishɔn
• I nɔ izi fɔ tɔk
• Di mɛmori we yu nɔ ebul fɔ mɛmba
• Di kɔndishɔn dɛn we pɔsin kin gɛt we i gɛt ɛpilepshɔn ( seizure ) .
• Di mɔsul dɛn we wik
• Rifleks dεm, sεns כ kכdכnayshכn dεm dεn dכn ridyus
• Fɔ lɔs filin na yu an ɛn yu fut

Imajin, sɔmbɔdi gɛt kansa na in lɔng, bɔt wantɛm wantɛm i kin bigin fɔ mɛmba tin, i kin swɛ in wɔd dɛn we i de tɔk, ɛn i nɔ kin izi fɔ mek i balans we i de waka. Na da tɛm de dɔktɔ dɛn kin sɔprayz se dis na (Paraneoplastic Syndrome) .

we di εndokrin sistεm de afekt

If yu ɔmon sistɛm afɛkt, yu kin gɛt sɔm sayn dɛn lɛk:

• Taya pasmak
• Di ay blɔd prɛshɔn
• Di mɔsul dɛn we wik
• Nɔs ɛn vɔmit
• We yu de gɛt bɔku bɔku wet wantɛm wantɛm ɛn nɔ gɛt ɛni rizin

we di joyn dεm, di bon dεm εn di mכsul dεm de afekt (Joints, bon dεm εn mכsul dεm - rεumatologic) .

If dɛn sistɛm ya afɛkt:

• Kɔndishɔn dɛn lɛk at at sik
• Joint pen, swel ɔ stiffness

We i de afɛkt di skin (Skin) .

Sɔntɛnde, di skin kin afɛkt bak:

• I de it
• Fɔ mek yu flash
• Skin we dɔn tik
• Benign (nɔ gɛt kansa) skin growth

Wetin na di kayn paraneoplastic syndromes?

Bɔku kayn Paraneoplastic Syndromes de . Dɛn kin sheb dɛn akɔdin to di we aw dɛn kin afɛkt ɛni sistɛm.

Nεv sistεm paranioplastik sεndrכm dεm

Sɔm ɛgzampul dɛn:

• `(Sεribεl dεjεnεreshכn)`: dis na damej pan di sεribεl, we de afekt tin dεm lεk bεlε εn waka.
• Dysautonomia: I de afɛkt di wok we di ɔtonomik nεv sistεm de du.
• Ɛnsɛfalaytis: Na inflamɛns na di bren.
• Ɛnsɛfalomaylaytis: Na inflamɛns na di bren ɛn spɛshal kɔd.
• Lambert-Eaton myasthenic syndrome (LEMS): I kin mek di mɔsul dɛn wik.
• Myasthenia gravis (MG): Dis na ɔda tin we kin mek di mɔsul dɛn wik.
• Maylopathy: Sik dɛn we kin afɛkt di spɛshal kɔd.
• Nyuromyotonia: Di mɔsul dɛn we de wok ɔltɛm.
• `(Opsoclonus-myoclonus syndrome)`: di abnכmal muvmεnt dεm na di yay εn mכsul dεm.
• `(Nyuropati (pεrifεral nyuropati))`: Dεmεj to di pεrifεral nεv dεm.
• `(Stiff-person syndrome)`: di mכsul dεm de stiff εn di kכntrikshכn dεm we de mek yu fil pen.

εndokrin sistεm paranioplastik sεndrכm dεm

Ɛgzampul dɛn:

• `(Cushing's syndrome): Na kכndyushכn we de kכz we di כmon kכtisol de inkrεs.
• Hypercalcemia: I de mek di kalsiɔm we de na di blɔd go ɔp.
• `(Syndrome of Inappropriate Antidiuretic Hormone Secretion (SIADH))`: Na wan kכndyushכn we de mek wata de rεtεn in bכdi bכku bכku wan.

Riumatik paranioplastik sindrom dɛn

(i de afekt di joyn dεm, di bon dεm, di mכsul dεm εn di kכnektiv tisu dεm)

Ɛgzampul dɛn:

• `(Eosinofilik fasciitis)`
• `(Eritromelaljia)`
• `(Haypertrofik ɔstiɔ-atrɔpati)`
• `(Palmar fasciitis)`
• `(Paraneoplastik polyarthritis)`

Blɔd paraniɔplastik sindrom dɛn

Ɛgzampul dɛn:

• `(Paraneoplastic erythrocytosis)`: di rεd bכdi sεl dεm de inkrεs.
• `(Paraneoplastic thrombocytosis)`: di blכd pletlet dεm de inkrεs.

Skin paranioplastik sindrom dɛn

Ɛgzampul dɛn:

• Acanthosis nigricans: Dak, tik pat dɛn na di skin.
• Dɛmatomyosaytis: Na inflamɛns na di skin ɛn di mɔsul dɛm.
• Leukocytoclastic vasculitis: Inflamεshכn pan sכm sכm bכdi vεsul dεm.
• `(Paraneoplastic pemphigus)`: Na wan kכndyushכn we de mek di skin blista.
• `(Sweet syndrome)`: Fiva ɛn pen na di skin.

Kidni paranioplastik sindrom dɛn

Paraneoplastic glomerulonephritis na wan sik wae de afɛkt di kidni dɛm.

Aw dɛn kin no bɔt paraneoplastic syndromes?

Yu dɔktɔ go no dis sik bay we i aks yu bɔt yu mɛdikal histri, du yu bɔdi ɛgzam, ɛn du sɔm ɔda tɛst dɛn.

• Nyurolɔjik ɛgzam: Bikɔs dis sik kin afɛkt di nervɔs sistɛm bɔku tɛm, yu dɔktɔ go aks yu fɔ du sɔm tin dɛn fɔ chɛk aw yu bren ɛn mɔsul dɛn de wok. Dɛn go chɛk fɔ si if yu gɛt chenj dɛn na yu trɛnk, yu mɛmori, ɛn yu kɔdineshɔn.
• Imej tɛst: Dɛn kin yuz tɛst lɛk CT skan , MRI , ɛn ɔltra saund fɔ si if tumbu de we de mek di sik de.
• Blɔd tɛst: Blɔd tɛst kin sho tin dɛn we kin mek pipul dɛn sɔprayz bɔt kansa. Dɛn kin chɛk bak fɔ antibodi dɛm we gɛt fɔ du wit paraneoplastic syndromes . Dɛn tɛst ya kin no bak if ɔda tin dɛn kin mek i gɛt dis sik, lɛk infekshɔn ɔ ɔmon nɔ balans.
• spεnal tap / lכmba pankshכn: sכm tεm dεn kin tεst yu sεribrospεnal fכluid (CSF) fכ si if antibodi dεm de we de atak hεlty sεl dεm. Dis min se yu fɔ put smɔl nidul na yu bɔdi we de dɔŋ ɛn tek wan sɛmpul pan di wata. Dɔn dɛn kin chɛk am.

Aw dɛn kin manej ɔ trit dɛn sik ya? (Aw dɛn kin manej ɔ trit di paraneoplastic syndromes?)

De tin wae impɔtant pas ɔl na fɔ trit de ɔndalayn kansa wae de kɔz yu sik. Na di sem tɛm, yu kin manej yu sik dɛn bak fɔ ridyus di damej pan yu bɔdi ɔgan ɔ sistɛm dɛn.

Sɔm pan di tritmɛnt dɛm wae dɛn kin yuse fɔ mɛn Paraneoplastic Syndromes :

• Kɔtikosterɔyd dɛn:Mεdikeshכn dεm lεk `(Cortisone)` כ `(prednisone)`. Dɛn tin ya de wok bay we dɛn de ridyus di inflamɛns (swɛlin) na di bɔdi.
• Immunosuppression: Na mεdikeshכn dεm we de ridyus di rεspכns fכ yu bכdi in imyun sistεm. Yu dɔktɔ go gi yu di mɛrɛsin bay di kayn paraneoplastic syndrome we yu gɛt.
• Intravenous immunoglobulin (IVIG): Dis tritmɛnt de wok bay we i de pwɛl di antibodi dɛm we de ambɔg am. insay dis, dεn kin gi hεlty antibodi dεm lεk injεkshכn, we de pwεl di antibodi dεm we de du bad.
• Plasmapheresis: Dis min se dɛn kin pul plasma (di wata pat na di blɔd) na di blɔd fɔ ridyus di antibodies, we de insay dis plasma ɛn we kin pwɛl di tisu we gɛt wɛlbɔdi.
• Fyzikal ɛn tɔk tɛrapi: Dis kin min fɔ ɛksesaiz di mɔsul dɛm fɔ mek yu ebul fɔ du tin dɛm lɛk fɔ tɔk ɛn muv fayn fayn wan. Yu kin nid dis tritmɛnt if yu gɛt paraneoplastic syndrome we gɛt fɔ du wit di nervous system.

Wetin a kin ɛkspɛkt if a gɛt paraneoplastic syndrome?

Yu prɔgnosis de dipen mɔ pan di stej we yu kansa de. Sɔmtɛm, de sayn dɛm wae dis sik kin kam wit kin nɔr kin sote ɛn fɔ sɔm tɛm. Ɔda tɛm, de sik kin tranga ɛn dɛn kin nid fɔ mɛn am fɔ lɔng tɛm.

Tɔk to yu dɔktɔ bɔt aw di stej we yu kansa gɛt ɛn di we aw yu de du tritmɛnt go afɛkt aw yu go wɛl.

Us kɔmplikɛshɔn dɛn kin gɛt fɔ du wit paraneoplastic syndromes?

Dis kin mek yu gɛt difrɛn prɔblɛm dɛn. Sɔm kin bi smɔl smɔl, ɛn ɔda wan dɛn kin siriɔs ɛn ivin de pan denja fɔ day if dɛn nɔ trit dɛn. Yu dɔktɔ go ɛksplen to yu di prɔblɛm dɛn we kin apin ɛn di tritmɛnt dɛn we yu kin gɛt.

Ustɛm a fɔ kɔl di dɔktɔ bɔt paraneoplastic syndromes?

If yu gɛt sayn dɛn fɔ paraneoplastic syndrome fɔ no rizin, go to dɔktɔ. Ɛspɛshali if yu dɔn gɛt tritmɛnt fɔ kansa insay di las fayv ia ɛn yu de gɛt dɛn kayn sik ya, i go fayn fɔ mek dɛn du tɛst bak. Dis go ɛp yu dɔktɔ bak fɔ no if di kansa dɔn kam bak.

Us kwɛstyɔn dɛn a fɔ aks mi dɔktɔ?

Sɔm kwɛstyɔn dɛn we yu kin aks yu dɔktɔ:

• Wetin na di kɔz fɔ mi sik dɛn?
• Aw mi (Paraneoplastic Syndrome) de afɛkt mi kansa tritmɛnt plan?
• Us tritmɛnt opshɔn dɛn a gɛt?
• MiAw Paraneoplastic Syndrome de afɛkt di we aw a de wɛl?
• Yu tink se di sik dɛn we a kin gɛt go bɛtɛ afta a dɔn trit mi kansa?
• Aw fɔ kɔntrol di sayn dɛm fɔ shɔt tɛm? Aw fɔ mɛn di sayn dɛm fɔ lɔng tɛm?

Fɔ dɔn, mɛsej we yu kin kɛr go na os

Tכmכro dεm we gεt kansa kin mek di bכdi chenj dεm we yu nכ bin de εkspεkt. Sɔntɛnde, dɛn kin gɛt sayn dɛn bak fɔ wan paraneoplastic syndrome . Bikɔs difrɛn kayn sik ya de ɛn de sik kin difrɛn, i kin tek sɔm tɛm fɔ mek yu dɔktɔ no se yu sik gɛt fɔ du wit kansa. Bɔt we dɛn dɔn no se i gɛt di sik, i kin trit di sayn dɛn ɛn di tin we impɔtant pas ɔl na fɔ trit di kansa we de ɔnda am .

Di bɛst we fɔ mɛn wan Paraneoplastic Syndrome na fɔ gɛt di tritmɛnt we go wok fayn fɔ di kansa. So, nɔ ignore ɛni symptom. If yu gɛt ɛni dawt, go to dɔktɔ kwik kwik wan. Na da tɛm de nɔmɔ wi ɔl go ebul fɔ gɛt wɛlbɔdi.

` Paraneoplastic sεndrכm, kεnsar, simptom dεm, nεv sεstem, εndokrin sistεm, imyun sistεm, kεnsar tritmεnt