Lɛ wi lan ɔltin bɔt Stem Cell Transplant insay wan simpul we.

Yu go mɔs dɔn yɛri bɔt stem sɛl transplant. Dɛn na rili wan tritmɛnt we rili yusful, we de sev layf fɔ sɔm sik dɛn. Bɔt dɛn kin tek sɔm tɛm fɔ mek dɛn wɛl ɔl. Wi go tɔk bɔt dis smɔl mɔ, lɛk se wi de tɔk to wi padi?

Wetin na Stem Sɛl dɛn?

Fɔ tɔk am simpul wan, stem sɛl na wan spɛshal kayn sɛl na wi bɔdi. Dɛn sɛl dɛn ya gɛt di wɔndaful pawa fɔ divɛlɔp to bɔku difrɛn kayn sɛl dɛn. di stεm sεl dεm we wi de tכk bכt na dis stεm sεl transplant na dεn de gi di imכtant sεl dεm na wi bכdi. Dat na:

• Rɛd blɔd sɛl dɛn: Na dɛn wan ya kin kɛr ɔksijɛn go ɔlsay na di bɔdi.
• Wait blɔd sɛl: Dɛn sɛl ya de protɛkt wi bay we dɛn de fɛt di jem ɛn sik dɛn we de kam insay wi bɔdi.
• Plɛtlɛt: Na dɛn wan ya kin ɛp fɔ mek blɔd klɔt we pɔsin gɛt injury.

Tink bɔt am lɛk se dɛn stem sɛl ya tan lɛk kle we dɛn kin mek ɛnitin. Dipen pan di nid, dɛn kin yuz am fɔ mek rɛd blɔd sɛl, wayt blɔd sɛl, ɔ pletlɛt.

Wetin mek dɛn kin du dɛn stem sɛl transplant ya?

Naw, lɛ wi si us kayn we dɛn stem sɛl transplant ya kin ɛp. Dis nɔto tin we dɛn kin du fɔ ɛvri sik, bɔt pan sɔm kayn bad bad tin dɛn, dis na di bɛst sɔlv.

• Fɔ pipul dɛn we gɛt siriɔs blɔd sik: Fɔ ɛgzampul, sɔm kayn lukimiya, we kin apin we di bon mɛrɔ nɔ de wok fayn.
• Fɔ pipul dɛm wae gɛt sɔm kayn kansa: Kansa lɛk lymphoma ɔr multiple myeloma.
• Fɔ di wan dɛn we gɛt siriɔs imyun dɛfisiɛns: Dɛn imyun sistɛm wik so dat dɛn bɔdi nɔ kin ebul fɔ fɛt sik dɛn.
• Fɔ pipul dɛm wae gɛt sɔm ɔtoimyun sik dɛm: Fɔ ɛgzampul, na sik dɛm lɛk lupus, we di bɔdi in yon sɛl dɛm atak di bɔdi.
• Dis tritmɛnt kin rili wok bak fɔ ɔda blɔd sik dɛn we pɔsin kin gɛt frɔm in mama ɛn papa: Thalassemia ɔ Sickle Cell Disease.

Usay wi kin gɛt dɛn stem sɛl ya?

Okay, naw yu go mɔs de wɔnda usay wi kin gɛt dɛn prɛshɔ stem sɛl ya. Tri men ples dɛn de we dɔktɔ dɛn kin gɛt dɛn sɛl ya:

1. Bon Marrow: Dis na di we we pipul dɛn lɛk pas ɔl. Bɔku tɛm dɛn kin kɔl dis ‘Bɔn Mɛro Transplant’. Bɔn mɛro na di pat we saf ɛn we tan lɛk spɔnj insay wi big bon dɛn. Na de dɛn de mek blɔd sɛl dɛn.

2. Tru di Blɔd: We dɛn gi spɛshal mɛrɛsin, di stem sɛl dɛn we kɔmɔt na di bon mɛro kin kɔmɔt na di blɔd, dɔn dɛn kin gɛda dɛn sɛl ya tru wan mashin we fiba di blɔd we dɛn kin gi ɔltɛm. Dɛn kɔl dis Pɛriferal Blɔd Stem Sɛl (PBSC) kɔlɛkshɔn.

3. 3. .di כmbilik kכd Blכd: afta dεn bכn di pikin, we dεn pul di כmbilik kכd, di bכdi we de lεf biεn de gεt dεn valyu stεm sεl dεm ya. Sɔmbɔdi we nid ɛp kin gɛda dɛn tin ya ɛn yuz dɛn.

dis we ya, wi kin kכl di pכsin we de gi di stεm sεl dεm ‘dכna' . Wetin rili impɔtant na dat, pan sɔm sik dɛn, di pɔsin we gɛt di sik kin bi in yon dona bak. Dat min se dɛn kin tek in yon stem sɛl dɛn bifo dɛn bigin fɔ trit di sik, dɛn kin frɔz dɛn, dɔn dɛn kin transplant dɛn bak to am we nid de. Dɛn kɔl dis ‘Autologous Transplant’ .

Bɔt bɔku tɛm, ɔda pɔsin kin gi dɛn sɛl dɛn ya. dis dεn kכl am ‘Allogeneic Transplant’ . if dεn tek stεm sεl dεm frכm כda pכsin, di jεnεtik mεkכp fכ dεn sεl dεm, spεshal wan di HLA (Human Leukocyte Antigen) mak dεm, fכ rili fiba. Fɔ tɔk am simpul wan, ɔl di sɛl dɛn na wi bɔdi gɛt smɔl ID kad. Dɛn tu ID kad ya fɔ rili fiba, if nɔto dat, di bɔdi nɔ go tek di nyu sɛl dɛn. Bɔku tɛm, na pikin in brɔda ɛn sista na di bɛst pɔsin fɔ mared. Sɔntɛnde, dɛn kin fɛn wan mach frɔm mama ɔ papa ɔ pɔsin we nɔ gɛt fambul fɔ gi mɔni. Big big database (rɛjista) dɛn de fɔ dis fɔ fɛn kɔmpatib donɔ dɛn.

Wetin kin apin if dɛn nɔ fɛn pɔsin we fit fɔ gi mɔni?

Imajin, if di stem sel dεm frכm di dכna nכ de εksakכt mach (sכmtεm ivin if dεn na pafεkt mach, dεn tin ya kin apin to big כ sכm), tu men prכblεm dεm kin kam:

1. Rijekshכn: Dis na we di sikman in imyun sistεm de atak di nyu dכna sεl dεm we dεn transplant. I de tink se, "Dis nɔto wi yon sɛl, dɛn tan lɛk fɔrina invayda dɛn," ɛn tray fɔ pwɛl dɛn. Dis kin bi bay we dɛn de yuz mɛrɛsin dɛn we de mek di bɔdi nɔ gɛt bɛtɛ wɛlbɔdi.

2. Graft-versus-Host Disease (GVHD): Dis na di ɔpɔzit. di nyu transplant dכna in imyun sεl dεm (spεshal wan di T-limfosayt dεm) de bigin fכ atak di hεlty sεl dεm na di sikman in bכdi, dεn de tink se, "Dis bכdi nכto wi yon." Dis kin afɛkt say dɛn lɛk di skin, di liva, ɛn di insay. Mɛrɛsin dɛn de fɔ kɔntrol dis bak.

Aw dis stεm sεl transplant prכsεs de apin?

Okay, so lɛ wi si aw dis transplant prɔses de wok. Na wan prɔses we gɛt bɔku tin dɛn fɔ du.

1. Aw fɔ pripia:

bifo dεn transplant stεm sεl, dכkta dεn go put sכmtin we dεn k כl ‘sεntral layn’, כ ‘sεntral venus kateta’ . Dis tan lεk wan big, spεshal IV (intravenous) layn. Dɛn kin put am insay big vein nia di at, ɔnda di skin na di nɛk, chɛst, ɔ groin. dis sεntri layn kin lεf in ples fכ lכng tεm pas wan rεgulεr IV. Dis kin mek am izi fɔ dɔktɔ ɛn nɔs dɛn fɔ gi yu mɛrɛsin, tek blɔd sɛmpul, ɛn gi yu di sɛl dɛn we dɛn dɔn transplant. Yu nɔ nid fɔ gɛt nidul ɔltɛm.

2. Kɔndishɔn tritmɛnt:

Dɛn kin du stem sɛl transplant na wan spɛshal yunit na di ɔspitul. Fɔs, dɛn kin gi di pɔsin we go gɛt di sɛl dɛn we de gi di mɔni (di pɔsin we gɛt di sik) ay dos fɔ kemotɛrapi ɛn/ɔ raytin fɔ sɔm dez. Dɛn kɔl dis kɔndishɔn tritmɛnt. Dɛn kin du dis fɔ tu men rizin dɛn:

• pwεl bad, bad bad sεl dεm (e.g. kεnsar sεl dεm, bon mכro sεl dεm we nכ de wok fayn) we de mek sik.
• Wik in imyun sistɛm so dat dɛn go ebul fɔ graft di nyu sɛl dɛn we dɛn dɔn gi fayn fayn wan we dɛn nɔ go rijɛkt dɛn.

3. Stem sel transplant: .

Afta di tritmɛnt dɔn, afta wan ɔ tu dez we dɛn rɛst, dɛn kin put di stem sɛl dɛn frɔm di pɔsin we gi di pɔsin tru wan sɛntral layn (jɔs lɛk aw dɛn de gi blɔd). Dis na tin we kin tek sɔm awa. Dɛn sɛl ya kin travul tru di blɔd ɛn setul na di bon mɛro, usay dɛn kin bigin fɔ mek nyu blɔd sɛl dɛn we gɛt wɛlbɔdi.

Wetin kin apin afta di transplant?

Afta pɔsin dɔn transplant stem sɛl, i kin tek sɔm tɛm fɔ mek in bɔdi mek nyu rɛd blɔd sɛl, wayt blɔd sɛl, ɛn pletlɛt. i kin tek lεk 2-4 wik fכ dεn nyu sεl dεm ya fכ bigin wok. Insay dis tɛm, di risk fɔ gɛt infɛkshɔn, blɔd, ɛn ɔda prɔblɛm dɛn kin rili bɔku. Dis na bikɔs di nɔmba fɔ di blɔd sɛl dɛn rili smɔl we dɛn de pwɛl di ol blɔd sɛl dɛn ɛn mek nyu wan dɛn.

Bɔrku pipul dɛn kin de na spɛshal rum na ɔspitul fɔ 3 to 5 wik (ɔ ivin lɔng pas dat) afta dɛn dɔn transplant dɛn. Insay dis tɛm, di mɛdikal tim kin rili tek tɛm wit dɛn tin ya:

• Dɛn kin du blɔd tɛst ɛvride fɔ si if dɛn de mek nyu blɔd sɛl dɛn frɔm di stem sɛl dɛn we dɛn dɔn transplant.
• Dɛn kin gi mɛrɛsin fɔ mek dɛn nɔ rijɛkt am ɛn fɔ mek dɛn nɔ gɛt Graft-versus-Host Disease (GVHD).
• Dɛn kin gi mɛrɛsin lɛk antibayɔtik, antifɔngal, ɛn antivayrɔs fɔ mek dɛn nɔ gɛt di sik.
• If nid de, dɛn kin gi rɛd blɔd sɛl ɛn pletlɛt dɛn na do (transfyushɔn).
• I de chɛk if ɔgan dɛn lɛk di liva ɛn di kidni de wok fayn fayn wan.
• Ɛni prɔblɛm lɛk we yu gɛt mɔt sos, vɔmit, dayarɛa, infɛkshɔn, blɔd, we yu nɔ gri fɔ tek, ɔ GVHD, dɛn kin trit am kwik kwik wan.
• Mek shɔ se di pɔsin de gɛt di rayt it. dis kin inklud tכb fכ it כ tכtal parenteral nyutrishכn (TPN).
• Dɛn kin chɛk ɔlman we kam na di ɔspitul fɔ mek shɔ se dɛn de fala di lɔ dɛn we de fɔ mek dɛn nɔ gɛt di sik. Dat min se:
• Nɔbɔdi wae gɛt ɛni sik (ivin kol) nɔr kin kam fɔ si di pɔrsin.
• Ɔlman fɔ was dɛn an fayn fayn wan bifo dɛn go insay di rum.
• Ɔlman fɔ wɛr mask, glɔv, ɛn klos.

Aw mama ɛn papa (if na pikin) go ɛp?

Afta we dɛn dɔn transplant di pikin we gɛt stem sɛl, in...I kin tek 6 to 12 mɔnt, ɔ ivin lɔng pas dat, fɔ mek di imyun sistɛm wɛl ɔlsay. Te da tɛm de, ivin smɔl smɔl sik dɛn kin rili at fɔ pikin dɛn. Ivin kɔmɔn kol kin denja. Na sɔm tin dɛn ya yu kin du fɔ ɛp fɔ protɛkt yu pikin frɔm infɛkshɔn:

• Yu pikin, yu fambul dɛm, ɛn pipul dɛm we de kam fɛn yu (we dɛn alaw fɔ kam fɛn yu) fɔ was dɛn an fayn fayn wan ɛn ɔltɛm wit antibakterial sop ɛn/ɔ han sɛnitayza. Dis na di tin we impɔtant pas ɔl.
• Nɔ briŋ ɛnibɔdi we sik nia di pikin.
• Bat yu pikin ɛvride wit shampoo ɛn sop we nɔ gɛt wan bɔt. Kip di skin klin.
• Fɔ fala di dɔktɔ in instrɔkshɔn dɛn gud gud wan:
• Ustɛm di pikin kin go na skul ɔ ɔda say dɛn we pipul dɛn kin gɛda (ples we pipul dɛn kin bɔku, sinima, shopin mal).
• Ustɛm pikin fɔ wɛr mask we i de go na do?
• Us it dεm we gud fכ di pikin fכ it εn us it dεm bad fכ di pikin fכ it (e.g. raw salad, mit we dεn nכ kuk εn fish).
• Di pikin kin de nia animal dɛn we i de mɛn ɛn tɔch dɛn?

Wetin bak wi nid fɔ no?

Bɔku pikin dɛn (ɛn big pipul dɛn) kin wɛl afta dɛn dɔn gɛt stem sɛl transplant. Bɔt di tɛm we dɛn kin spɛn na ɔspitul ɛn di tɛm we dɛn kin spɛn fɔ wɛl na os kin bi prɔblɛm fɔ di pɔsin ɛn in famili, pan dɛn maynd ɛn bɔdi.

"No tray fɔ go dis joyn yu wan. Aks fɔ ɛp."

Gɛt sɔpɔt frɔm ɔda famili mɛmba dɛm, padi dɛm, yu mɛdikal tim, advaysa, ɔr soshal woka. Yu kin jɔs tek kia ɔf yu pasɛnt (ɔ pikin, if na pikin) gud gud wan if yu tek kia ɔf yusɛf gud gud wan.

Fɔ ɛp yu pɔsin fɔ wɛl ɛn fɔ gɛt wɛlbɔdi, du dɛn tin ya:

• Kip ɔl di fɔlɔp dɔktɔ visit dɛm ɛn gi yu mɛrɛsin di rayt tɛm.
• Sɔpɔt ɛn ɛnkɔrej di pɔsin we sik we i de chenj in bɔdi (e.g., in ia de lɔs, i taya, i de chenj in skin) we kin apin bikɔs ɔf kemotɛrapi ɛn/ɔ redyushɔn.
• Ɛp dɛn fɔ dil wit de wanwɔd ɛn isolation wae kin kam wae dɛn kin de fa frɔm padi ɛn fambul wae dɛn de wɛl. Gi chans fɔ tɔk, ivin bay vidio kɔl.
• Aks di sikman if i go lɛk fɔ tɔk to advays ɔ soshal woka fɔ ɛp am fɔ dil wit filin lɛk pwɛl hat, fred, ɛn vɛks we kin kam we i de wɛl.
• Ɛp di pɔsin (espɛshali pikin) fɔ mek wan simpul tin fɔ du ɛvride we gɛt fɔ du wit layt ɛksesaiz (if di dɔktɔ gri fɔ am), it ɔltɛm, ɛn tin dɛn we i lɛk fɔ du, lɛk fɔ ple, fɔ rid, ɛn fɔ drɔ.

Ustɛm wi nid fɔ go to dɔktɔ kwik kwik wan?

Sɔm risk dɛn de we yu go bak na os afta yu transplant. If yu gɛt ɛni wan pan dɛn sayn ya:Yu nid fɔ kɔl di dɔktɔ wantɛm wantɛm, ɛn yu nɔ fɔ delay fɔ ivin wan minit, ɔ dɛn nid fɔ kɛr yu go na ɔspitul:

• If di tɛmpracha na 38.0°C (100.4°F) ɔ pas dat we yu si am frɔm yu mɔt (dis na di sayn we denja pas ɔl).
• If yu nos de rɔn, yu kɔf, yu chɛst tayt, ɔ yu nɔ ebul fɔ blo.
• If yu de vɔmit ɔ dayarɛa kɔntinyu fɔ de.
• If yu de pas blak, tarry stɔl (poops) (dis kin bi sayn fɔ blɔd na di intestines).
• If yu brus izi wan ɔ yu gɛt blɔd we yu nɔ go ebul fɔ stɔp (e.g. frɔm yu nos ɔ yu gɔm).
• If blɔd de na di urine, ɔ if di urine in kɔlɔ dɔn chenj.
• If yu gɛt siriɔs ed pen, yu ed de tɔn, ɔ yu nɔ de si fayn.
• I nɔ bad fɔ kɔf blɔd, bɔt if yu nɔ ebul fɔ kɔntrol di blɔd we de kɔmɔt na yu nos insay sɔm minit, .
• If nyu tin apia na di bɔdi, lɛk fɔ gɛt rash.

Fɔ dɔn, sɔm impɔtant tin dɛn we wi fɔ mɛmba

So, wan stem sel transplant kin bi wan tritmɛnt we rili saksesful, we kin chenj layf fɔ sɔm siriɔs sik dɛn. Bɔt na big tin we dɛn kin du, ɛn fɔ mek pɔsin wɛl, i kin tek tɛm, peshɛnt, ɛn gi in layf to Gɔd. Di tin we impɔtant pas ɔl na fɔ fala di dɔktɔ in instrɔkshɔn dɛn gud gud wan, gi di pɔsin (if na pikin, di pikin) lɔv, lɔv, ɛn sɔpɔt we nɔ de shek, ɛn mɔ fɔ protɛkt am frɔm infɛkshɔn.

Mɛmba se nɔto yu ɛn yu pasɛnt nɔmɔ de du dis tranga waka! Di mɛdikal tim, famili, ɛn padi dɛn ɔl de wit yu. If yu gɛt ɛni kwɛstyɔn ɔ dawt, ilɛksɛf i smɔl, nɔ fred fɔ aks di mɛdikal tim. Dɛn de de fɔ ɛp yu.

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