Yu gɛt smɔl pletlɛt dɛn na yu blɔd? Lɛ wi tɔk bɔt dis (Thrombocytopenia)!

Aw di bɔdi? Tide wi go tɔk bɔt wan sik we kin tan lɛk se i siriɔs smɔl, bɔt if dɛn ɔndastand am fayn, dɛn kin kɔntrol am to bɔku bɔku wan. Dat na di rεdukshכn fכ di pletlεt dεm na di bכdi, wan kכndyushכn we dεn kכl (Thrombocytopenia) insay mεdikal tεm dεm. Yu go dɔn yɛri dis wɔd frɔm dɔktɔ, ɔ yu go dɔn si am na blɔd ripɔt. Nɔ wɔri, wi go tɔk bɔt dis simpul wan, di we we yu go ɔndastand.

Fɔs, lɛ wi si wetin na dɛn blɔd pletlɛt ya ɛn wetin mek dɛn rili impɔtant to wi?

Tink bɔt dis we: pletlɛt na di smɔl smɔl tin dɛn we tan lɛk sojaman we de rɔn tru wi blɔd vesel dɛn. Fɔ tɔk di kɔrɛkt tin, dɛn na wan kayn sɛl we rili smɔl ɛn we nɔ gɛt kɔlɔ. Lɛk di ɔda sɛl dɛn na wi blɔd, dɛn kin mek pletlɛt dɛn na di sɔft tisu we de insay wi bon dɛn we dɛn kɔl bon mɛro.

Naw yu de aks, so wetin mek wi nid dɛn smɔl sojaman ya? Na di impɔtant tin ya: We wi wund sɔmsay ɛn bigin fɔ blɔd, lɛk we wi de go fɛt wɔ, na dɛn pletlɛt ya kin rɔsh go de ɛn jɔyn togɛda fɔ mek blɔd klot (`(klɔt)`) fɔ stɔp di blɔd. I tan lɛk we yu put sɔm simen na ol na wɔl. So, if yu nɔ gɛt pletlɛt, ivin smɔl wund nɔ go ebul fɔ stɔp di blɔd. Yu ɔndastand aw dat impɔtant?

So, wetin na dis low pletlet count, ɔ trombocytopenia?

Fɔ tɔk am simpul wan, trombocytopenia na we yu blɔd gɛt smɔl pas di nɔmal nɔmba fɔ di pletlɛt dɛn. Nɔmal wan, pɔsin we gɛt wɛlbɔdi kin gɛt bitwin 1.5 ɛn 4.5 milyɔn pletlɛt dɛn pan wan maykrolita blɔd. we dis nכmba dכn dכn dis, wi kin kכl am trombocytopenia.

Bɔt na di tin ya: we di pletlɛt dɛn we de na di bɔdi go dɔŋ smɔl, nɔto big tin ɔltɛm. I dipen pan aw i smɔl, wetin mek i fɔdɔm, ɛn aw i fɔdɔm kwik kwik wan. Na dat mek i impɔtant fɔ go to dɔktɔ to advays.

Wetin mek wi nɔ gɛt bɔku bɔku pletlɛt? Wetin na di tin dɛn we kin mek i apin?

Difrɛn rizin dɛn kin de fɔ mek di blɔd pletlɛt dɛn nɔ bɔku. Lɛ wi sheb dɛn to tri men kategori.

1. If di bon mכro we de mek bכdi pletlet dεm dכn dכn:

Wi bin dɔn tɔk bɔt aw dɛn kin mek pletlɛt dɛn na di bon mɛro. So, if prכblεm de wit dis bon mכro εn di pletlet dεm we de mek di pletlet dεm dכn dכn, di nכmba fכ di pletlεt dεm na di bכdi de dכn. Bɔku rizin dɛn de we kin mek dis apin:

• Sɔm vayral infɛkshɔn: Fɔ ɛgzampul, infɛkshɔn lɛk dengi fiva, ɛpatitis C, ɛn HIV kin mek yu bon mɛro nɔ wok fayn.
• Sɔm mɛrɛsin dɛn: Di mɛrɛsin dɛn we dɛn kin yuz fɔ mɛn kansa (Kemotherapy), sɔm antibayɔtiks, ɛn diuretics kin afɛkt di bon mɛrɔ bak.
• If yu drink pasmak: Dis kin pwɛl di bon mɛrɔ bak.
• di vaytamin dεm we de dכn: If di bכdi nכ gεt inof vaytam in B12 (`(Vitamin B12)`) כ fכlet (`(Folate)`), di prodakshכn fכ di bכdi pletlet dεm kin dכn.
• Blɔd kansa: Blɔd kansa lɛk lukimiya kin mek di bon mɛro stɔp fɔ mek nɔmal sɛl dɛn.
• Aplastic Anemia: Dis na we di bon mɛro nɔ de mek ɛni blɔd sɛl fayn fayn wan.
• Myelodysplastic Syndromes: Dis na kכndyushכn bak we di bon mכro nכ de wok fayn fayn wan.
• di jεnεtik kכndishכn dεm we nכ kin apin: sכmtεm, di lכw pletlεt prodakshכn kin kכz fכ jεnεtik kכz dεm we de de we dεn bכn am.

2. If di pletlet dεm we dεn prodyuz de pwεl kwik כ if dεn yuz dεm pasmak na di bכdi:

Sɔntɛnde, ivin if di bon mɛrɔ de mek inof pletlɛt, if dɛn pwɛl kwik kwik wan insay di bɔdi, ɔ if dɛn yuz am tumɔs bikɔs ɔf big blɔd, di pletlɛt dɛn kin go dɔŋ.

• ITP (Immune Thrombocytopenic Purpura): Dis na we wi imyun sistɛm mistek atak ɛn pwɛl wi yon blɔd pletlɛt dɛn. Dis kin apin to yɔŋ pikin dɛn afta dɛn dɔn gɛt vayral fiva, bɔt i kin apin bak to big pipul dɛn.
• Dis kin apin bak pan ɔda sik dɛm wae de mek pɔrsin ebul fɔ fɛt insɛf, lɛk lupus ɛn rεumatoid at.
• Sɔm mɛrɛsin dɛn: Sɔm mɛrɛsin dɛn kin mek di imyun sistɛm pwɛl di blɔd pletlɛt dɛn, ivin as alɛji.
• Sivεr infεkshכn (sepsis): Insay siriכs infεkshכn, kכndyushכn lεk DIC (Disseminated Intravascular Coagulation) kin apin, we kin mek di blɔd pletlεt dεm dכn kwik kwik wan.
• TTP (Thrombotic Thrombocytopenic Purpura) (`(Thrombotic Thrombocytopenic Purpura)`) ɛn HUS (Hemolytic Uremic Syndrome) (`(Hemolytic Uremic Syndrome)`): Dɛn tin ya nɔ kin apin so ɔltɛm bɔt dɛn kin denja. pan dis kכndyushכn, sכm sכm blכd kכlכt dεm de fכm insay di bכdi vεsul dεm εn di pletlεt dεm de yus כp.

3. If di splin big ɛn di pletlɛt dɛn gɛda de:

di splin na wan כgan we de na di כp pat na di lεft say na wi bכdi. I de filta blɔd ɛn pul di ol blɔd sɛl dɛn. if di splin big bikoz fכ sכm sik dεm (e.g., liva sik - sirosis, sכm infεkshכn, bכdi kεnsar), i kin gεt mכr pletlet dεm pas nכmal, we kin mek di nכmba fכ di pletlet dεm na di bכdi dכn.

Us sayn dɛn kin apin we di blɔd pletlɛt dɛn nɔ bɔku?

Di sayn dɛm wae de sho se pɔrsin gɛt bɔrku pletlet kin difrɛn frɔm wan pɔrsin to ɔda pɔrsin. I dipen bak pan aw yu pletlɛt dɛn smɔl ɛn aw dɛn kin drɔp kwik kwik wan. Sɔmtɛm pipul dɛm wae gɛt smɔl pletlɛt nɔr kin gɛt ɛni sayn atɔl. Bɔt, na sɔm pan di sayn dɛm wae kin kam pan pɔrsin wae gɛt dis sik:

• Brus: Brus na big, blu ɔ pepul spat na di skin. Ivin smɔl bɔmp ɛnisay kin mek big brus.
• Smɔl rɛd dɔt dɛn na di skin:sכmtεm, sכm rεd כ pepul dכt dεm (`(petechiae)`) de apin כlsay na di bכdi, lεk sכm sכm ant, na di lεg εn an. Dɛn tin ya nɔ kin dɔn we yu luk dɛn.
• I kin tek lɔng tɛm fɔ mek di blɔd stɔp afta we pɔsin wund.
• Gɔm we de blɔd, blɔd we de kɔmɔt na yu nos ɔltɛm.
• Blɔd we de kɔmɔt na di urine ɔ di stɔl (di urine kin rɛd, di stɔl kin blak ɔ blɔd).
• Fɔ uman dɛn, di mɔnt we dɛn kin gɛt kin ebi ɛn i kin las fɔ mɔ dez pas aw i kin bi.
• Fɔ fil taya, taya.
• Sɔntɛnde, if i gɛt fɔ du wit liva prɔblɛm, di yay kin tɔn yɔlɔ (jaundice).

Impɔtant: If yu gɛt sɔm sayn dɛn lɛk ed we de at, fil lɛk yu nɔ ebul fɔ tɔk, ɔ i nɔ izi fɔ tɔk, yu fɔ go na ɔspitul wantɛm wantɛm, bikɔs dis kin bi sayn fɔ se blɔd de kɔmɔt insay yu bren!

If wi gɛt sayn dɛn lɛk dis, wetin wi fɔ du? Yu tink se wi fɔ go to dɔktɔ?

Yɛs, fɔ tru! If yu gɛt ɛni blɔd we nɔ kɔmɔn, blɔd spat na yu skin, ɔ yu taya pasmak, nɔ ignore am ɛn go to dɔktɔ. Nɔ panik, bɔt nɔ delay sɛf. Di dɔktɔ go aks yu kwɛstyɔn dɛn, chɛk yu, ɛn rifer yu fɔ mek dɛn du tɛst if nid de.

Aw di dɔktɔ kin no bɔt dis? Us kayn tɛst dɛn kin du?

We yu go to dɔktɔ, dɛn go aks yu fɔs bɔt di sik dɛn we yu gɛt, di mɛrɛsin dɛn we yu de tek, ɛn if ɛnibɔdi na yu famili dɔn gɛt dis kayn prɔblɛm. Dɔn dɛn go chɛk yu ɛn chɛk fɔ si if yu gɛt blɔd, yu skin dɔn chenj, ɛn if yu splin dɔn big.

Apat frɔm dat, i pɔsibul fɔ du tɛst dɛn lɛk:

• Ful Blɔd Kɔnt (FBC) : Dis na di men tɛst we de sho di rayt nɔmba fɔ di pletlɛt dɛn we de na di blɔd. I de gi infɔmeshɔn bak bɔt rɛd blɔd sɛl ɛn wayt blɔd sɛl.
• Peripheral Blood Smear : Dis min se yu tek wan sεmpl fכ bכdi εn luk di shep εn saiz fכ di pletlet dεm כnda maykroskכp. Sɔntɛnde, dɛn kin luk bak fɔ si if di pletlɛt dɛn dɔn stɔp togɛda ɔ if ɛni sɛl dɛn de we nɔmal.
• Ɔda blɔd tɛst: Ɔda tɛst dɛn de we kin ɛp fɔ no di tin we mek i kam. fכ egzampl, tεst fכ chεk di liva fכnshכn (liva fכnshכn tεst), kidni fכnshכn tεst, tεst fכ chεk fכ vayral infεkshכn, εn tεst fכ chεk fכ כtoimyun mak dεm.
• Bone Marrow Aspiration and Biopsy : Sɔntɛnde, if blɔd tɛst nɔmɔ nɔ sho di kɔz, dɛn kin du dis tɛst fɔ si if di bon mɛro de mek pletlɛt fayn fayn wan. Dis min se yu fɔ tek smɔl bon mɛrɔ frɔm smɔl say lɛk di hip ɔnda anestezi.

Wetin na di tritmɛnt fɔ di blɔd pletlɛt dɛn we nɔ gɛt bɛtɛ blɔd?

Dis na prɔblɛm we bɔku pipul dɛn gɛt. Di tritmɛnt fɔ di pletlɛt dɛn we nɔ gɛt bɛtɛ trɛnk de dipen ɔl pan wetin mek i kam ɛn aw di sik siriɔs. No wan saiz-fit-ɔl sɔlv nɔ de.

• Fɔ di wan dɛn we gɛt smɔl smɔl pletlɛt kɔnt: If di pletlɛt kɔnt nɔ tu smɔl ɛn nɔ sayn de fɔ se dɛn de blɔd, sɔntɛnde dɛn nɔ nid ɛni tritmɛnt, jɔs fɔ wach wit blɔd tɛst ɔltɛm.
• Fɔ trit di ɔndalayn kɔz:
• If wan mɛrɛsin dɔn mek yu pletlɛt dɛn nɔ bɔku, yu dɔktɔ go tɛl yu fɔ stɔp fɔ tek di mɛrɛsin ɔ chenj yu to ɔda mɛrɛsin. Yu tink se i bɛtɛ fɔ lɛ yu nɔ stɔp fɔ tek di mɛrɛsin?
• If na bikɔs ɔf infekshɔn, dɛn kin trit da infɛkshɔn de.
• If na ɔtoimyun sik, dɛn kin trit am.
• Tritmɛnt dɛn we spɛshal fɔ di blɔd pletlɛt dɛn we nɔ gɛt bɛtɛ blɔd:
• Kɔtikosterɔyd : Fɔ ɛgzampul, mɛrɛsin dɛn lɛk prɛdnisolon. dεn kin gi dεn tin ya fכ stכp di imyun sistεm fכ pwεl di bכdi pletlet dεm (insay kכndishכn lεk ITP).
• Intravenous Immunoglobulin (IVIG): Dis na mɛrɛsin we tan lɛk salin we dɛn kin gi insay wan vein. Dɛn kin yuz am fɔ mek di pletlɛt dɛn bɔku kwik kwik wan pan siriɔs kes dɛn usay di imyun sistɛm de pwɛl di blɔd pletlɛt dɛn.
• Ɔda mɛrɛsin dɛn we de kɔntrol di imyun sistɛm (immunosuppressants): Dɛn kin gi dɛn tin ya if stɛroyd nɔ de wok ɔ if di sayd ɛfɛkt dɛn tu bad.
• thrombopoietin receptor agonists (TPO-RAs): dis mεdikeshכn dεm de mek di bon mכro fכ mek mכr pletlet dεm.
• Plɛtlɛt Transfyushɔn: If yu de blɔd bɔku ɔ if yu pletlɛt kɔnt rili smɔl ɛn i denja fɔ smɔl (e.g. bifo dɛn du ɔpreshɔn), dɛn kin gi yu pletlɛt na do. Bɔt, dis na jɔs fɔ sɔlv di prɔblɛm fɔ sɔm tɛm.
• Splenectomy: If dɛn si se di splin de pwɛl di pletlɛt, ɛn ɔda tritmɛnt dɛn nɔ de wok (espɛshali we dɛn de du ITP fɔ lɔng tɛm), dɛn kin du ɔpreshɔn fɔ pul di splin. Bɔt we yu pul di splin, i kin mek yu gɛt di sik mɔ ɛn mɔ.
• Plasma exchange (ɔ Plasmapheresis): Dɛn kin yuz dis tritmɛnt na spɛshal kɔndishɔn lɛk TTP.

Wetin wi fɔ wɔri bɔt we wi de liv wit dis sik?

Pipul dɛn we gɛt smɔl blɔd pletlɛt nid fɔ tek tɛm smɔl na dɛn layf ɛvride.

• Nɔ du tin dɛn we go mek pɔsin fɔdɔm ɛn wund. Fɔ ɛgzampul, kɔntakt spɔt nɔ fayn.
• Tek tɛm bad bad wan we yu de yuz shap tul ɔ we yu de kɔt vɛjitebul.
• Yuz saf tut brɔsh we yu de brus yu tit. Tek tɛm mek yu nɔ wund yu gam.
• Fɔ tek blɔd tin dɛn lɛk aspirin, NSAID (lɛk ibuprofen) we yu nɔ gɛt dɔktɔ in advaysNɔ yuz dɛn tin ya. Dɛn tin ya kin mek di blɔd bɔku. Tɛl ɔl dɔktɔ ɛn dɛntist we yu si se yu gɛt smɔl pletlɛt.
• Yu fɔ no ɛni sayn we de sho se yu de blɔd (skin spat, blɔd na yu nos, yu gɔm we de blɔd). Tɛl yu dɔktɔ if yu notis ɛni nyu sayn.
• It di it we balans. If yu pletlɛt nɔ bɔku bikɔs yu nɔ gɛt bɛtɛ vaytamɛn, it nɔmɔ nɔ go mɛn am. Bɔt, i impɔtant fɔ gɛt di it we yu bɔdi nid.
• Limit ɔ stɔp fɔ drink rɔm ɔltogɛda .

Yu tink se dis kin rili siriɔs? Wetin na di prɔblɛm dɛn we kin apin?

Yɛs, dis kin bi siriɔs sik if di pletlɛt kɔnt go dɔŋ bad bad wan ɔ wantɛm wantɛm.

Di men tin we kin mek pɔsin gɛt prɔblɛm na we i de blɔd bad bad wan. dis kin bi fכ si (frכm wund, nos) כ insay (e.g., insay di bren, bεlε, intestines). Blɔd we de kɔmɔt insay pɔsin in bɔdi kin mek pɔsin in layf de pan denja.

Na dat mek i rili impɔtant fɔ tek di tritmɛnt jɔs lɛk aw di dɔktɔ se ɛn fɔ tek tɛm.

Sɔma ɛn las wɔd dɛn

Okay, so a op se naw yu dɔn ɔndastand mɔ bɔt wetin wi bin tɔk bɔt tide (Thrombocytopenia) ɔ di blɔd pletlɛt dɛn we nɔ bɔku. Mɛmba se dis min se di pletlɛt dɛn we de na di blɔd smɔl pas aw i fɔ bi. Bɔrku tin kin de wae kin mek pɔrsin gɛt dis sik, ɛn de sik kin difrɛn fɔ ɛnibɔdi.

Di tin we impɔtant pas ɔl na dat, if yu gɛt dɛn sik ya, instead fɔ disayd fɔ yusɛf, ɔ luk fɔ mɛrɛsin na di Intanɛt, fɛn gud dɔktɔ, fɛn di rayt tin we mek yu gɛt dis sik, ɛn gɛt di rayt tritmɛnt fɔ am.

Nɔr wɔri, bɔrku tɛm, wit di rayt tritmɛnt ɛn manejmɛnt, yu kin kɔntrol dis sik ɛn liv gud layf. Bi opin ɛn ɔnɛs to yu dɔktɔ bɔt ɔltin, ɛn aks ɛni kwɛstyɔn we yu gɛt. Dis go ɛp yu fɔ ɔndastand dis mɔ ɛn ɛp yu fɔ bia wit di prɔblɛm.

` trombocytopenia, pletlet kaunt, pletlet, bon mכro, blɔd, brus, ITP, blɔd sik, Sinhala mεdikal atikul, petechiae