Yu bɔdi in imyun sistɛm na wɔndaful difens sistɛm. Bɔt sɔntɛnde dis sistɛm kin wok difrɛn we smɔl. Sɔntɛnde i kin bi ɔva aktiv ɛn ambɔg wi yon bɔdi, ɔ sɔmtɛm i kin nid ɛp fɔ fɛt ɛnimi lɛk kansa sɛl. Insay dɛn kayn tin ya, wi de tɔk bɔt wan spɛshal tritmɛnt we de ɛp wi imyun sistɛm ɛn kɔntrol di wok we i de du. Dat na fotofɛrɛsis.
Fɔ tɔk am simpul wan, wetin na fotofɛrɛsis?
Fɔtofɛresis na tritmɛnt we de yuz layt fɔ chenj di wok we yu wayt blɔd sɛl dɛn de du, we dɛn kɔl limfosayt. Dɛn sɛl ya we dɛn kɔl limfosayt na di men sojaman dɛn fɔ wi imyun sistɛm. Dɛn kin pwɛl tin dɛn lɛk kansa sɛl, baktri, ɛn vayrɔs. So, if prכblεm de wit dεn limfosayt dεm ya, fכtofεresis tritmεnt de bכku yusful.
Tink bɔt am dis we. Dɛn kin tek sɔm pan yu blɔd, put am na mashin, ɛn na di wayt blɔd sɛl dɛn nɔmɔ we dɛn kɔl limfosayt dɛn kin sheb am. Dɔn, dɛn kin miks am wit wan spɛshal mɛrɛsin ɛn put am na UV layt, we kin chenj di we aw dɛn sɛl dɛn de wok. Fɔ dɔn, dɛn kin put dɛn sɛl ya we dɛn dɔn trit bak insay yu bɔdi wit di ɔda pat dɛn na yu blɔd.
Tru dis we, wi kin mek wi imyun sistɛm strɔng, ɔ kɔntrol am if i de du tin di we we wi nɔ want. In ɔda wɔd, dis tritmɛnt gɛt di abiliti fɔ ‘tɔn di swich ɛn ɔf’ di imyun sistɛm as nid de.
Us kɔndishɔn dɛn kin yuz dis tritmɛnt fɔ?
Fɔtofɛrɛsis na wan kayn imyunotɛrapi. Dat min se na we fɔ trit sik dɛn bay we wi de yuz wi yon imyun sistɛm. Bɔku men tin dɛn de we dɛn kin yuz fɔ am.
| Mɛdikal kɔndishɔn | Wan simpul ɛksplen |
|---|---|
| Kutan T-sεl limfoma (CTCL) . | Dis na wan kayn blɔd kansa we nɔ kin bɔku ɛn we kin afɛkt di skin. Dɛn bin fɔs bigin fɔ yuz fotofɛresis tɛrapi as tritmɛnt fɔ dis sik. we di limfosayt dεm we dεn trit de kam bak na di bכdi, dεn de εp fכ pwεl di kεnsar sεl dεm. |
| Graft versus Ɔs sik (GVHD) . | Afta sɔntin lɛk bon mɛro transplant, di nyu stem sɛl dɛn we dɛn dɔn gɛt kin bigin fɔ atak yu yon bɔdi lɛk se na ‘ɛnimi.’ Dis tritmɛnt kin stɔp ɔ kɔntrol da atak de we dɛn nɔ want. |
| Ɔgan transplant we dɛn nɔ gri wit | Afta dɛn dɔn transplant wan big ɔgan, lɛk lɔng, liva, ɔ at, di bɔdi in imyun sistɛm kin rijɛkt di nyu ɔgan. Dis tritmɛnt de ɛp fɔ mek dat nɔ apin. |
Ɔda tin dɛn we kin apin to pɔsin we sik
Apat frɔm dɛn men tin ya, dɔktɔ dɛn kin se dɛn fɔ yuz fotofɛrɛsis fɔ sɔm ɔda mɛrɛsin dɛn.
- Di sik we dɛn kɔl Crohn in sik
- Ekzema (Atɔpik dɛmatitis) .
- Sklɛrodama
- Psoriasis, we na wan sik we de na di skin
- Tayp 1 dayabitis
Aw wi fɔ rɛdi bifo wi gɛt tritmɛnt?
Yu dɔktɔ go ɛksplen dis to yu. Bɔrku tɛm, dɛn go aks yu fɔ tek kia ɔf dɛn tin ya bifo yu gɛt tritmɛnt.
- Drink bɔku wata: Drink at le 8 glas wata ɛvride fɔ tu dez bifo yu trit yu. Dis go ɛp yu blɔd fɔ flɔ fayn fayn wan, ɛn dis go mek i izi fɔ pul blɔd we yu de trit yu.
- Nɔ it kafinɛ ɛn rɔm: Tin dɛn lɛk ti, kɔfi, ɛn rɔm kin mek di bɔdi nɔ gɛt wata, ɛn dis kin mek di blɔd nɔ flɔ sloslo.
- Nɔ it tin dɛn we gɛt fat: We yu it tin dɛn we gɛt bɔku fat, lɛk it dɛn we dɛn dɔn frɛsh ɛn swit, i kin at smɔl fɔ mek di mashin we de sheb di wayt blɔd sɛl dɛn frɔm di blɔd du in wok.
Aw dis tritmɛnt kin wok?
Dis ɔltin kin apin we yu de ledɔm fayn fayn wan na bed. Na tin we pɔsin kin du we nɔ de mek pɔsin fil pen.
1. Blɔd pul: Nɔs ɔ dɔktɔ go pul blɔd frɔm wan vein na yu an ɔ tru wan spɛshal tiub (kateta) we dɛn put na yu chɛst. If nid de, dɛn kin put krim we de mek pɔsin nɔ fil fayn na di say we i de fɔ mek i nɔ fil pen.
2. Sεl dεm we de separet:Di blɔd we yu tek kin go dairekt insay wan spɛshal mashin. Dis mashin de separet di wayt blɔd sɛl dɛn nɔmɔ we dɛn kɔl limfosayt frɔm di rɛd blɔd sɛl dɛn ɛn di pletlɛt dɛn we de na yu blɔd.
3. Ad mεdikeshכn: dεn ad wan sef εbul mεdisin we dεn kכl `8-methoxypsoralen (8-MOP)` to di wayt bכdi sεl dεm we dεn separet. Dis mɛrɛsin kin wok nɔmɔ we dɛn put am na layt.
4. Layt tɛrapi: Naw, di wayt blɔd sɛl dɛn we de wit dis mɛrɛsin de put ɔltra vayolɛt A layt (UVA layt) insay di mashin. Dɔn, di mɛrɛsin kin bigin fɔ wok ɛn chenj di we aw di wayt blɔd sɛl dɛn de wok.
5. Riinfusion: Fɔ dɔn, di wayt blɔd sɛl dɛn we dɛn dɔn trit dis we ya, dɛn kin put am bak insay yu bɔdi, wit di ɔda blɔd komponent dɛn we dɛn bin dɔn separet bifo.
Dis ɔl prɔses kin tek lɛk 3-4 awa.
Wetin na di sayd ɛfɛkt ɛn tin dɛn we wi fɔ no bɔt?
Dɛn kin tek fotofɛresis as tritmɛnt we rili sef , ɛn bɔku pipul dɛn nɔ kin gɛt ɛni sayd ɛfɛkt.
Bɔt, sɔntɛnde, smɔl smɔl tin dɛn kin apin.
- Yu blɔd prɛshɔn kin go dɔŋ smɔl we yu de trit yu. If dis apin, dɛn kin gi yu wata we de insay yu bɛlɛ fɔ mek i kam bak to nɔmal.
- Yu kin fil nɔys, diziz, ɔ kol, jɔs lɛk we yu de gi blɔd. If yu fil dis kayn we, tɛl di nɔs wantɛm wantɛm.
- Yu kin gɛt rɛd, diziz, ɔr yu kin gɛt fiva 6-8 awa afta yu dɔn trit yu. If yu fiva pas 37.8 digri sɛlshiɔs (100 digri F), tɛl yu dɔktɔ. I kin se yu fɔ tek mɛrɛsin lɛk paracetamol.
Tin dɛn we wi nid fɔ tek tɛm mɔ bɔt afta wi dɔn gɛt tritmɛnt
Dis rili impɔtant. Fɔtofɛresis tritmɛnt kin mek yu skin ɛn yay rili sɛnsitiv to san layt.
Nɔ put yusɛf pan dairekt ɛn indayrɛkt san fɔ 24 awa afta yu dɔn trit yu. Indaykt san layt na layt we de kɔmɔt na winda ɔ kɔtin.
- If yu go na do, wɛr klos we kɔba yu wan ol bɔdi. Yuz sanskrin we gɛt SPF we na 30 ɔ pas dat.
- Wear sanglas we de protɛkt yu frɔm UVA rayt, insay os ɛn na do, fɔ 24 awa. "wraparound" sanglas we de kɔba ɔl tu di yay dɛn na di bɛst.
Aw lɔng i kin tek fɔ si di rizɔlt?
Dis go difrɛn difrɛn wan fɔ yu kɔndishɔn ɛn di nɔmba fɔ di tritmɛnt dɛn. Sɔm pipul kin si bɔrku impɔtant improvement pan dɛn symptoms insay 3-4 mɔnt. Fɔ sɔm kayn tin dɛm (lɛk sklɛrodama), i kin tek 6-12 mɔnt fɔ mek di sayn dɛm bɛtɛ. So, i impɔtant fɔ peshɛnt wit dis tritmɛnt. Aks yu dɔktɔ bɔt di tɛm we yu kin ɛkspɛkt fɔ si di rizɔlt bay aw yu sik.
Mɛsej we dɛn kin kɛr go na os
- Fɔtofɛresis na sef tritmɛnt we de yuz layt fɔ trit yu yon wayt blɔd sɛl ɛn kɔntrol di wok we di imyun sistɛm de du.
- Dɛn kin yuz dis mɔ fɔ tin dɛn lɛk CTCL kansa, GVHD kɔndishɔn, ɛn fɔ mek dɛn nɔ rijɛkt afta dɛn dɔn transplant ɔgan.
- Di tritmɛnt nɔ de mek pɔsin fil pen, bɔt i fɔ protɛkt am frɔm di san fɔ 24 awa afta dɛn dɔn trit am.
- I kin tek sɔm tɛm fɔ si di rizɔlt, so i impɔtant fɔ peshɛnt ɛn go to tritmɛnt.
- Tɔk to yu dɔktɔ opin wan bɔt ɛni prɔblɛm, fred, ɔ dawt we yu gɛt pan dis.
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