Yu gɛt dɛn strenj sayn ya bak? Lɛ wi tɔk bɔt Plasmacytoma

Pen we yu nɔ ebul fɔ ɛksplen na difrɛn pat dɛn na di bɔdi, sɔm tɛm dɛn kin gɛt prɔblɛm wit di bon dɛn we yu nɔ kin ebul fɔ imajin, ɔ di tin dɛn we nɔ kin apin na di sɔft tisu dɛn na say dɛn lɛk di nɛk ɛn ed... Dɛn tin ya na tin dɛn we sɔm tɛm dɛn nɔ kin pe bɔku atɛnshɔn to. Bɔt insay sɔm kayn tin dɛn we nɔ kin apin so ɔltɛm, dɛn tin ya kin bi sayn fɔ wan sik we nɔ kin apin so ɔltɛm we dɛn kɔl Plasmacytoma. Nɔr wɔri, dis nɔto sik wae de ambɔg bɔrku pipul dɛm. Bɔt i rili impɔtant fɔ no bɔt dis.

Wetin na dis plasmacytoma? Lɛ wi ɔndastand am rili simpul wan.

Fɔ tɔk am simpul wan, Plasmacytoma na wan sik we fiba Multiple Myeloma, bɔt i nɔ kin apin so ɔltɛm. Wi ɔl gɛt wan kayn sɛl na wi bɔdi we dɛn kɔl Plasma sɛl . Sɔm pipul dɛn kin kɔl dɛn B sɛl ya bak. Dɛn tin ya na impɔtant pat pan wi imyun sistɛm. Plasma sɛl dɛn we gɛt wɛlbɔdi de mek antibodi ɔ immunoglobulins we de ɛp wi bɔdi fɔ fɛt sik.

Bɔt sɔntɛnde, dɛn wɛlbɔdi plasma sɛl dɛn ya kin bi abnɔmal ɛn bigin fɔ sheb ɛn bɔku tumɔs kwik kwik wan. afta dat dεn abnכmal sεl dεm ya kin gεt εn fכm tכmכro. Dɛn tumbu ya kin fɔm na wi bon dɛn, na di saf saf tisu dɛn na wi ed ɛn nɛk, ɔ na ɛni ɔgan lɛk blad, lɔng, ɔ kidni.

Aw Plasmacytoma de afɛkt mi bɔdi?

As wi bin dɔn tɔk bɔt bifo tɛm, dis prɔblɛm kin bigin we di wɛlbɔdi plasma sɛl dɛn nɔ kin wok fayn. dis abnכmal plasma sεl dεm de mכltiply εn mek wan abnכmal tכp antibodi we dεn kכl M protin dεm . we dεn M protin dεm ya de inkrεs, di nכmba fכ rial, hεlty plasma sεl dεm we rili εp fכ protεkt wi frכm sik de dכn. Dis min se wi imyuniti kin wik.

Tu men kayn plasmacytoma de, i dipen pan us pat na di bɔdi i kin afɛkt:

1. Solitary Plasmacytoma of Bone (SPB): Dis na we abnכmal plasma sεl dεm de fכm tכmכro na wan bon na yu bכdi. Tink bɔt am lɛk jɔs wan vertebra na yu spayna, ɔ jɔs wan spat na yu hip. Dis SPB kin mek yu bon dɛn pwɛl ɛn mek yu fil pen. Na lɛk 50% pan di pipul dɛm wae gɛt SPB go dɔn gɛt mɔltipɛl mayloma.

2. Extramedullary Plasmacytoma (EMP): Insay EMP, wan tכmכro we dεn mek wit abnכmal plasma sεl dεm de afekt sכft tisu . Sɔft tisu na di tisu we de rawnd, kɔnɛkt, ɛn sɔpɔt wi ɔgan ɛn bon dɛn. Fɔ ɛgzampul, dis kin min wi mɔsul dɛn, di tɛndon dɛn, wi skin, wi fat, ɛn di fascia. EMP kin apin na eni sכft tisu na di bכdi, bכt i kin kכmכn mכst na di כp rεspiretכri trakt.. Dat min se, na ples dεm lεk di nos, di sayn dεm, di nos, εn di larynx. Bɔt i kin apin na ɛni ɔgan. Na lɛk 15% pan di pipul dɛm wae gɛt EMP kin leta gɛt mɔltipɛl mayloma.

Udat kin gɛt dis plasmacytoma? Aw i kɔmɔn?

Dɛn kin si plasmacytoma pan pipul dɛm wae ol bitwin 55 ɛn 60. Dɛn dɔn si bak se man kin gɛt dis sik pas uman dɛm.

Plasmacytoma na rili wan sik we nɔ kin apin so ɔltɛm . Dɔktɔ dɛn kin jɔs no lɛk 450 nyu kes dɛm fɔ SPB ɛn lɛk 300 nyu kes dɛm fɔ EMP ɛvri ia. Bɔt sɔm pipul dɛn we dɔn de fɛt fɔ lɔng tɛm wit di sik we dɛn kɔl multiple myeloma kin gɛt plasmacytoma bak.

Wetin na di sayn dɛm fɔ SPB?

Solitary Plasmacytoma of Bone (SPB) na wan sik we de mek yu bon gɛt pen ɔ we yu bon brok . Fɔ ɛgzampul, yu kin gɛt bak pen wantɛm wantɛm fɔ no rizin, ɔ yu kin gɛt pen na yu rib. Ɔda sayn dɛm fɔ SPB na:

• Pen ɔ frakt na say dɛn lɛk yu rib, yu tɔrɔsik vɛrbra, yu fim, ɛn yu bɛlɛ .
• Kכmpreshכn frakshכn dεm na di spayna. Dis kin mek yu spɛnal kɔd ɔ yu nerve rut dɛn pwɛl. If dis apin, yu kin gɛt shap pen we de chuk yu ɛn we kin travul dɔŋ yu leg ɛn go insay yu bak.
• Na smɔl tɛm nɔmɔ if SPB afɛkt di skel, i kin mek yu ed at, yu ed kin tɔn, ɛn yu nɔ kin si fayn .

So wetin na di sayn dɛm fɔ EMP?

di simptom dεm fכ Extramedullary Plasmacytoma (EMP) kin apin we di tכmכro prεs pan sכft tisu, we kin mek i fil pen εn i kin disrupt di bכdi fכ wok.

Fɔ ɛgzampul, if yu gɛt EMP insay yu nos, yu kin fil lɛk se sɔntin dɔn stɔp na yu nos, ɛn i kin at fɔ blo tru yu nos. pan ɔl we EMP kin apin ɛnisay na di bɔdi, 80% to 90% pan di kes dɛm kin apin na di ed ɛn nɛk eria. Di kɔmɔn simptom dɛm fɔ EMP na:

• Ed de at
• Dischaj we de kɔmɔt na di nos
• I nɔ kin izi fɔ swɛla (Dysphagia) .
• Trot we de at ɔ infekshɔn (Pharyngitis) .
• Nɔs blɔd (Epistaxis) .

Na smɔl tɛm nɔmɔ, if di EMP afɛkt yu larynx (voys bɔks), yu kin gɛt sɔm sayn dɛn bak lɛk:

• Fɔ mek pɔsin ala lawd lawd wan
• Di say we di briz de blo we dɔn ambɔg
• We pɔsin de swɛt

Impɔtant:Bɔrku tɛm, dɛn plasmacytoma simptom ya kin tan lɛk ɔda sik dɛm wae nɔr kin siriɔs. So nɔ panik if yu si sɔntin lɛk dis. Bɔt if dɛn sayn ya nɔ de fɔ pas tu wiks ɔ i de wɔs, yu fɔ rili go to dɔktɔ.

Wetin mek dis plasmacytoma de fɔm? Wetin na di kɔz?

Infakt, wi no naw se plasmacytoma kin kam bikɔs di plasma sɛl dɛn we gɛt wɛlbɔdi kin tɔn to sɛl dɛn we nɔmal ɛn we kin bɔku we wi nɔ ebul fɔ kɔntrol. Bɔt, di wan dɛn we de stɔdi bɔt dis stil nɔ no bɛtɛ bɛtɛ wan wetin de mek dis chenj. Dat min se dɛn nɔ dɔn fɛn ɛni patikyula rizin yet.

Aw dɔktɔ dɛn kin no se pɔsin gɛt Plasmacytoma?

Dɔktɔ dɛn kin yuz bɔku tɛst fɔ no di kayn plasmacytoma ɛn if i de, fɔ no di stej we EMP gɛt.

Na sɔm pan dɛn tɛst dɛn de:

• CT scan (Computed Tomography - CT scan): Dis de yuz X-ray ɛn kɔmpyuta fɔ mek wan tri-dimɛnshɔnal (3D) pikchɔ fɔ yu sɔft tisu ɛn bon dɛn. Dɔktɔ dɛn kin yuz CT skan fɔ luk fɔ di bon dɛn we dɔn pwɛl bikɔs ɔf plasmacytomas.
• MRI skan (Magnetic Resonance Imaging - MRI): Dis tεst kin tek ditayli pikchכ dεm fכ yu bכdi we yu nכ yuz rεdyushכn. MRI kin ɛp fɔ asɛs di sɔft tisu damej we EMP kin mek.
• Blɔd ɛn urine tɛst: Dɛn kin yuz dɛn tɛst ya fɔ no di lɛvɛl dɛn na dɛn M protin dɛn we wi bin tɔk bɔt.
• Nasal endoscopy: if dεn sכspεkt se EMP kכndishכn de, dεn kin yuz dis prosidכs fכ egzamin di pasej dεm εn di sayn dεm insay di nos. Dis min se yu fɔ pas wan tiub we gɛt smɔl kamɛra insay di nos.
• fayn-nidul bayopsi: dεn kin yuz dis mεtכd fכ gεt sεmpl fכ tisu εn fכluid frכm sכft tisu dεm we EMP afekt.
• Bayopsi: Dɛn kin du dis bak fɔ tek sɛmpul pan tisu ɔ wata fɔ chɛk di plasma sɛl dɛn. dis na fכ kכnfכm if eni sεl dεm de we nכ nכmal.

Wetin na di stej dɛm fɔ EMP?

Dɔktɔ dɛn kin tink bɔt dɛn tin ya fɔ no di stej we di Extramedullary Plasmacytoma (EMP) gɛt:

• Stej I: Tεst dεn sho se na wan tכmכro nכmכ de na wan ples na yu bכdi.
• Stej II: di tεst dεm sho se di EMP sεl dεm de insay yu limf no dεm bak.
• Stej III: Tεst dεm sho se i pas wan EMP tכmכro.

Wetin na di tritmɛnt dɛm fɔ Plasmacytoma?

Di bɛst tin na dat, tritmɛnt dɛn de fɔ dis sik. Dɔktɔ dɛn kin trit solitary plasmacytoma of bone (SPB) wit redyushɔn tɛrapi.Sɔntɛnde, if pɔsin gɛt dɛn abnɔmal prɔtin (M protin) dɛn de na in blɔd ɔ urine ɛn i gɛt plasmacytoma bak, dɔktɔ dɛn go yuz tritmɛnt bak fɔ multiple myeloma.

Dɛn kin trit ɛkstra ɔs plasmacytoma (EMP) wit ɔpreshɔn ɛn/ɔ kemotɛrapi ɔ imyunotɛrapi . Yu dɔktɔ go disayd di tritmɛnt we go fayn fɔ yu bay di sik we yu gɛt.

Yu tink se dɛn kin stɔp di divɛlɔpmɛnt fɔ plasmacytoma?

infakt, lεk mכltipכl maylכma, nכ we dεn nכ no fכ mek di plasmacytoma nכ gεt divεlכpmεnt. Bikɔs wi nɔ no di rayt tin we kin mek i apin, i nɔ kin izi fɔ tɔk aw fɔ mek i nɔ apin.

Aw lɔŋ yu kin liv wit Plasmacytoma?

Dis na prɔblɛm fɔ bɔku pipul dɛn. Na lɛk 60% pan di pipul dɛm wae gɛt SPB stil de alayv fayv ia afta dɛn dɔn no bɔt dɛn sik. Na lɛk 82% pan di pipul dɛm wae gɛt EMP stil de alayv fayv ia afta dɛn dɔn no bɔt dɛn sik. Dis na jɔs statystik, dis kin difrɛn frɔm wan pɔsin to ɔda pɔsin.

Bɔt i sɔri fɔ no se sɔntɛnde, plasmacytoma kin kam bak , ɔr kin kam ɔdasay na di bɔdi. Dɔn bak, sɔm pipul dɛn we gɛt SPB ɔ EMP kin leta gɛt mɔltipɛl mayloma. Dis kin afɛkt aw lɔng dɛn de liv.

Aw a kin kia fɔ misɛf? Wetin a fɔ du?

Bikɔs wan sik we dɛn kɔl plasmacytoma kin divɛlɔp to multiple myeloma, if yu gɛt plasmacytoma, yu go nid fɔ kia fɔ yu fɔ ɔl yu layf ivin afta dɛn dɔn dɔn di tritmɛnt. Dis rili impɔtant.

Dis fכlכ-ap kεriכn kin inklud rεgulεr blכd tεst εn imej tεst (lεk CT εn MRI). Dɛn dɔktɔ ya go wach yu fɔ si if yu gɛt sayn dɛn we de sho se yu gɛt bɔku bɔku mayloma. If yu gɛt plasmacytoma, aks yu dɔktɔ us kayn fɔlɔp kia yu fɔ ɛkspɛkt.

Plasmacytoma na wan blɔd sik we nɔ kin apin so ɔltɛm we fiba di multiple myeloma. Bɔt gud tin na dat, dɔktɔ dɛn kin ebul fɔ trit bɔku pan di wan dɛn we gɛt plasmacytoma fayn fayn wan, ɛn dis kin mek di tumbu smɔl ɛn mek dɛn nɔ gɛt di sik. Bɔt fɔ no se yu gɛt plasmacytoma min se yu go gɛt fɔ liv wit mɛdikal fɔlɔp fɔ di res ɔf yu layf. E nɔr izi fɔ liv wit wan sik wae nɔr de ɛva go ɔlsay. If yu de liv wit plasmacytoma, aks yu dɔktɔ bɔt aw fɔ ɛp yu fɔ bia wit dis sik we nɔr de dɔn. Dɛn go gladi fɔ ɛp yu.

Fɔ dɔn, tin dɛn fɔ mɛmba (Take-Home Message) .

Okay, so lɛ wi rikap sɔm pan di tin dɛn we yu nid fɔ mɛmba frɔm wetin wi dɔn tɔk bɔt:

• Plasmacytoma na sik we nɔ kin apin so ɔltɛm we di tɔŋ dɛn we de kɔmɔt na di plasma sɛl dɛn nɔ kin apin .
• tu men kayn dis de: SPB, we de afekt di bon dεm , εn EMP, we de afekt di sכft tisu dεm .
• Di sayn dɛm kin bi we yu gɛt bon pen, yu bon dɛn kin brok, ed kin at, yu nos kin rɔn, ɛn i nɔ kin izi fɔ swɛla . If dɛn sayn ya kɔntinyu ɔr de wɔs, go to dɔktɔ.
• Dɛn nɔ dɔn fɛn wan patikyula tin we kin mek dis apin yet , so no we nɔ de fɔ mek i nɔ apin.
• Sɔm tritmɛnt dɛn de lɛk redyushɔn tɛrapi, ɔpreshɔn, kemotɛrapi, ɛn imyunotɛrapi .
• Fɔ fala ɔl yu layf afta tritmɛnt rili impɔtant, bikɔs dis kin divɛlɔp to mɔltipɛl mayloma ɔ kam bak.
• Fɔ liv wit dis sik kin tranga. Tɔk to yu dɔktɔ ɛn gɛt di sɔpɔt we yu nid.

A op se dis infɔmeshɔn go yusful to yu. Stay wit wɛlbɔdi!

` plasmacytoma, kansa, blɔd sik, bon kansa, sɔft tisu kansa, multiple myeloma