Lɛ wi no bɔt Primary Biliary Cholangitis (PBC), we na wan sik we nɔ de tɔk natin ɛn we kin afɛkt di liva

Bɔku tɛm yu kin fil taya ɔ yu kin it fɔ natin? Sɔntɛnde, wi nɔ kin pe atɛnshɔn tumɔs to dɛn tin ya as nɔmal tin na wi ɛvride layf. Bɔt sɔntɛnde, dɛn tin ya kin bi sayn we de wɔn wi frɔm insay wi bɔdi. Mɔtalman, dɛn kin bi di fɔs sayn dɛn we de sho se wi gɛt prɔblɛm wit wi liva. Tide wi go tɔk bɔt wan sik we kin afɛkt di bɔdi kwayɛt wan. Dat na Praymari Biliary Cholangitis, ɔ PBC fɔ shɔt.

Fɔ tɔk am simpul wan, wetin na Praymari Biliary Cholangitis (PBC)?

Imajin se insay yu liva, wan sistem de we gɛt fayn fayn smɔl smɔl tiub dɛn. I tan lɛk di branch dɛn na tik we de branch. Dis na wetin wi kin kɔl bayl dakt. di men wok we dεn dakt ya de du na fכ kכri di wata we dεn kכl ‘Bile’ we di liva de mek kכmכt na di liva, dat na fכ go insay wi dijestiv sistεm. Dis bayl impɔtant fɔ wi, bikɔs na dis bayl de ɛp fɔ sɔlv di fat dɛn we de insay di it we wi de it.

Naw, insay wan sik we dɛn kɔl Primary Biliary Cholangitis (PBC), wi yon imyun sistɛm kin mistek atak dɛn bayl dakt ya. Dis kin mek di bayl dakt dɛn inflamɛns ɔ swel. As tɛm de go, dis inflamɛns kin pwɛl di bayl dakt dɛn ɛn smɔl smɔl i kin pwɛl dɛn.

Wetin kin apin da tɛm de? lεk wata paip we klos, di bayl nכ kin fכ fכlכ εn i kin stכk insay di liva. di bayl we stik de bigin fכ damej di liva sεl dεm. as dis damej de kכntinyu, ska tisu de bigin fכ fכm in ples fכ di hεlty liva tisu. Afta sɔm tɛm, di liva kin at smɔl smɔl ɛn di wok we i de du nɔ kin wok igen. Wi kin kɔl dis kɔndishɔn sirosis . Trade, dɛn bin de kɔl dis sik bak Primary Biliary Cirrhosis.

Yu tink se dis sik rili siriɔs?

PBC na sik we de go bifo ɛn we nɔ de mɛn. Dis min se i nɔ kin bɛtɛ wan nɛt, ɛn di sayn dɛm kin wɔs as tɛm de go. Na di fɔs tɛm, i nɔ kin gɛt ɛni sayn atɔl. Bɔt if dɛn nɔ kɔntrol di sik, leta i kin mek di liva nɔ wok fayn. Da tɛm de, i kin mek pɔsin in layf de pan denja if dɛn nɔ transplant di liva.

Udat kin gɛt dis sik pas ɔlman?

Wan tin we de sho se wi de tɔk bɔt dis sik na dat i kin rili bɔku pan uman dɛn.Dat na. Fɔ ɛvri man we gɛt dis sik, na lɛk 10 uman dɛn kin gɛt am. Na gap de we tan lɛk dat.

• Bɔrku tɛm, dɛn kin no dis sik afta dɛn dɔn ol 40 ia.
• Dɔn bak, if sɔmbɔdi na yu famili gɛt ɔda sik dɛn we pɔsin kin gɛt we i de fɛt insɛf , yu kin gɛt wan sik, we kin sho se i kin gɛt sɔntin fɔ du wit in jɛnɛtiks.

Wetin na di simptom ɛn kɔmplikeshɔn dɛm fɔ PBC?

Bɔrku pipul nɔr kin gɛt ɛni sayn wae de sik kin bigin. Sɔmtɛm dɛn kin kam fɔ no am bay we dɛn du blɔd tɛst fɔ ɔda rizin. Bɔt as di sik de go bifo, sɔm sayn dɛn kin bigin fɔ sho.

Kɔmɔn sayn dɛm wae kin kam fɔs

• Taya: Dis na di sayn wae de sho se yu taya pas ɔl. I nɔ mata aw yu de slip ɔ rɛst, di taya we yu de fil nɔ de go.
• Itchy skin: I kin apin, mɔ na di an ɛn di fut dɛn we de na di fut. Bɔt, i kin apin ɛnisay na di bɔdi. Fɔ sɔm pipul dɛn, di it kin mek dɛn nɔ ebul fɔ bia.

Dɛn sayn ya nɔ kin apin di sem we fɔ ɔlman. Fɔ sɔm, dɛn kin apia rayt we di sik bigin, bɔt fɔ ɔda pipul dɛn, dɛn kin apin leta.

Kɔmplikɛshɔn dɛm wae kin apun as de sik de go bifo

We di bayl nɔ ebul fɔ flɔ fayn, i kin bigin fɔ gɛda na wi blɔd. Dɔn bak, prɔblɛm kin apin bikɔs di dijestiv sistɛm nɔ de gɛt bayl. As di liva skata de go ɔp, prɛshɔn de bɔku bak pan di blɔd vesel dɛn we de pas na di liva. Dis kin mek yu gɛt difrɛn prɔblɛm dɛn. Lɛ wi luk dɛn tin ya na wan tebul.

Wetin na di rial tin we kin mek pɔsin gɛt PBC?

As wi bin dɔn tɔk, PBC na sik we pɔsin kin gɛt we i de fɛt insɛf . Fɔ tɔk am simpul wan, wi bɔdi in "ami" (di imyun sistɛm) kin mistek atak wi yon gud sɛl dɛn. I tan lɛk se wi de atak wi yon kɔntri pipul dɛn, tink se dɛn na ɛnimi. insay PBC, dis "atכk" de apin pan di bayl dakt dεm na di liva.

Dɔktɔ dɛn stil nɔ no bɛtɛ bɛtɛ wan wetin mek dis kin apin, bɔt dɛn biliv se sɔm tin dɛn de we kin mek i apin:

1. Jɛnɛtik factor: If pɔsin na di famili gɛt dɛn sik ya, ɔda pipul dɛn kin gɛt dɛn sik ya bak.

2. Di tin dɛn we de apin na di envayrɔmɛnt: We wan vayrɔs, baktri, ɔ kemikal kam insay di bɔdi, di imyun sistɛm fɔ pɔsin we gɛt di jenɛtiks kin mek i nɔ wok fayn.

Aw dɛn kin no dis sik? (Diagnosis) .

We yu tɛl yu dɔktɔ bɔt yu sik, i go chɛk yu ɛn ɔda fɔ du bɔku tɛst fɔ no if yu gɛt di sik.

1. Blɔd Tɛst: Dis na di tɛst we impɔtant pas ɔl. Tu tin dɛn de we dɛn kin luk fɔ spɛshal wan.

• Antibodi: Na lɛk 95% pan di pipul dɛm we gɛt PBC gɛt wan patikyula antibodi we dɛn kɔl Antimitochondrial Antibody (AMA) na dɛn blɔd.
• di liva εnzym dεm: we di liva dεn dכn pwεl, sכm εnzym dεm (especially Alkaline Phosphatase - ALP ) de inkrεs na di bכdi.

2. Imej Tɛst: If blɔd tɛst sho se yu gɛt PBC, yu dɔktɔ kin ɔda fɔ mek dɛn skan yu fɔ luk yu liva ɛn gal blad. Dis kin ɛp bak fɔ pul ɔda tin dɛn we kin mek yu gɛt di sik. Bɔku tɛm, na ɔltra saund skan na di fɔs tɛst we dɛn kin du. Dɛn kin du MRI skan fɔ mek dɛn gɛt klia pikchɔ dɛn.Yu kin rifer bak to wan.

3. Liva Bayopsi: Sɔntɛnde (espɛshali pan pipul dɛn we nɔ gɛt AMA antibodi na dɛn blɔd), dɛn kin tek wan rili smɔl pat pan di liva tisu ɛn chɛk am ɔnda maykroskɔp fɔ kɔnfɔm di diagnosis ɛn fɔ no di rayt we aw di liva dɔn pwɛl.

Wetin na di tritmɛnt dɛm fɔ PBC?

No mɛrɛsin nɔ de fɔ PBC yet. Bɔt, tritmɛnt dɛn de we rili fayn fɔ ridyus di damej we di sik de mek di liva nɔ pwɛl, fɔ kɔntrol aw di sik de go bifo, ɛn fɔ kɔntrol di sayn dɛm.

Mɛrɛsin we dɛn kin gi

• Ursodeoxycholic acid (UDCA): Dis na di men mɛrɛsin fɔ PBC. Na wan bayl asid we de na di wɔl. Dis mɛrɛsin de ɛp fɔ pul di bayl na di liva ɛn i de ridyus di liva we de pwɛl. I kin rili woke wae yu bigin fɔ gɛt di sik kwik kwik wan.
• Ɔda mɛrɛsin dɛn: Fɔ di wan dɛn we nɔ de tek UDCA fayn, yu dɔktɔ kin tɛl yu fɔ tek ɔda mɛrɛsin lɛk ɔbikolik asid . Apat frɔm dat, dɛn de yuz nyu mɛrɛsin dɛn lɛk seladelpar ɛn elafibrinor naw.
• Mɛrɛsin fɔ di sayn dɛm:
• Fɔ di skin we de it: Dɛn kin yuz mɛrɛsin dɛn lɛk Cholestyramine, antihistamines, ɛn ultraviolet light therapy.
• Fɔ di wan dɛn we nɔ gɛt vaytamɛn: Dɛn kin gi sɔpɔtmɛnt dɛn we gɛt vaytamɛn A, D, E, ɛn K.
• Fɔ taya: Sɔm pipul dɛn kin gɛt sɔm rilif frɔm mɛrɛsin dɛn we de mek pɔsin fil fayn lɛk modafinil.

Ɔpreshɔn

If yu liva de kɔntinyu fɔ wok fayn ɛn dɛn nɔ de kɔntrol am wit mɛrɛsin, yu dɔktɔ kin put yu pan di list fɔ wet fɔ mek dɛn transplant yu liva . Liva transplant fɔ PBC kin rili wok fayn. Yu kin liv nɔmal layf afta di transplant. pan ɔl we i pɔsibul fɔ mek PBC kam bak na di nyu liva, i nɔ kin apin so ɔltɛm.

Wetin a fɔ no bɔt fɔ liv wit dis sik?

Bɔku tɛm, PBC kin go bifo smɔl smɔl. I kin tek 15-20 ia fɔ mek di sik rich in las stej. If dɛn no di sik ɛn trit am kwik, dɛn kin ebul fɔ avɔyd di sik bad bad wan ɔ dɛn kin delay. Bɔrku pipul dɛn kin kɔntrol dɛn sik wit mɛrɛsin ɛn liv fɔ lɔng tɛm ɛn nɔr kin gɛt big prɔblɛm wit dɛn ɛvride layf.

Bɔt sɔm pipul dɛn kin gɛt dis sik kwik kwik wan. If yu taya pasmak ɛn di bilirubin we de na di blɔd go ɔp, dat kin bi sayn fɔ sho se di sik de go bifo kwik kwik wan.

Tin dɛn we yu kin du fɔ protɛkt yu liva

If yu fala gud layf ɛn it, dat go ɛp fɔ mek yu liva gɛt wɛlbɔdi fɔ lɔng tɛm.

• Stɔp fɔ smok, fɔ drink rɔm, ɛn fɔ tek drɔgs we nɔ nid fɔ du am kpatakpata.Dɛn tin ya kin rili ambɔg di liva.
• It mɔ ɔl it dɛn lɛk fresh vɛjitebul, frut, ɛn ɔyl instead fɔ it tin dɛn we dɛn dɔn prosɛs ɛn pak.
• Ridyus di satεrayt fεt dεm εn pik it dεm we gεt כnsatyuret כ "gud" fεt dεm (e.g. avokado, nכt, כliv כyl).
• Gɛt sɔm ɛksesaiz ɛvride. Ivin sɔntin we simpul lɛk fɔ waka fayn. We yu de du ɛksɛsayz fɔ bia wet, dat kin ɛp fɔ mek yu bon dɛn strɔng.

Fɔ liv wit wan sik wae nɔr de dɔn lɛk dis kin mek yu taya na yu maynd. Tɔk to yu dɔktɔ bɔt aw fɔ ridyus yu bɔdi, maynd, ɛn filin. Luk fɔ advays if nid de. Mɛmba se yu ɔl yu wɛl bɔdi bɛtɛ pas dis sik.