Yu no bɔt dis sik we nɔ kin bɔku na yu bren we dɛn kɔl PML? (Progresiv Maltifokal Lukoɛnsɛfalɔpati - PML)

Yu ɔ pɔsin we yu sabi dɔn ɛva gɛt yu bɔdi we nɔ gɛt bɛtɛ trɛnk, i nɔ izi fɔ waka, ɔ yu abit chenj wantɛm wantɛm? Pan ɔl we dɛn tin ya kin tan lɛk kɔmɔn tin, sɔntɛnde, siriɔs rizin kin de biɛn dɛn. Tide wi go tɔk bɔt wan pan dɛn kayn bren infɛkshɔn ya we nɔ kin apin so ɔltɛm, bɔt we rili siriɔs. Dɛn kɔl dis Progressive Multifocal Leukoencephalopathy , ɔ PML fɔ shɔt tɛm.

Fɔ tɔk am simpul wan, wetin na PML?

PML na wan sik we rili siriɔs ɛn we nɔ kin apin so ɔltɛm we kin afɛkt wi bren. Di men rizin fɔ dis na bikɔs wi bɔdi in ebul fɔ fɛt sik, dat na di imyun sistɛm, rili wik.

Naw luk, wi bren gɛt sɔntin we de protɛkt am rawnd di nɛv sɛl dɛn. I tan lɛk di plastic sheath we de rawnd ilɛktrik waya. Wi kɔl dis maylin . dis maylin sεt de εp di mεsej dεm fכ travul tru di nεv dεm kwik εn kכrekt wan. we PML de apin, dis maylin sεt de pwεl. I tan lɛk se di plastic sheath we de pan da waya de de mɛlt. Dɔn di mɛsej dɛn we de na di bren nɔ de travul fayn, we kin mek i gɛt prɔblɛm wit aw i de waka, aw i de tink, ɛn aw i de fil.

Dis sik na wan vayrɔs we dɛn kɔl JC vayrɔs . I sɔprayz fɔ no se lɛk 85% pan di big pipul dɛn kin kɛr dis vayrɔs na dɛn bɔdi we nɔ gɛt ɛni prɔblɛm. As lɔng as wi imyun sistɛm strɔng, dis vayrɔs nɔ de tɔk natin. Bɔt if wi imyun sistɛm wik bad bad wan, dis vayrɔs kin bigin fɔ wok wantɛm wantɛm ɛn bigin fɔ atak di bren.

Wetin na di sayn dɛm fɔ PML?

Di sayn dɛm fɔ PML kin difrɛn difrɛn wan bay usay na di bren di damej de. Lɛ wi tek wan luk pan di fɔs ɛn let simptom dɛm fɔ dis sik.

Udat de pan denja fɔ gɛt dis sik?

Dis na sik we nɔ kin apin so ɔltɛm. Bɔku tɛm, i kin afɛkt lɛk wan pan ɛvri tu ɔndrɛd tawzin pipul dɛn. Bɔt sɔm pipul dɛn kin gɛt mɔ prɔblɛm. Lɛ wi si udat dɛn bi.

• Pipul dɛn we gɛt HIV/AIDS: Na bikɔs dis sik de atak di imyun sistɛm dairekt wan.
• Sɔm pipul dɛn we gɛt kansa: Ɛspɛshali di wan dɛn we gɛt kansa we gɛt fɔ du wit blɔd lɛk lukimiya ɛn limfoma.
• Di wan dɛn we dɛn kin transplant ɔgan: We dɛn transplant ɔgan (lɛk kidni ɔ liva) frɔm ɔda pɔsin, dɛn kin gi dɛn tin dɛn we de mek dɛn nɔ ebul fɔ fɛt di bɔdi fɔ mek di bɔdi nɔ gri fɔ tek am. Dɛn pipul ya kin gɛt ay risk bak.
• Pipul dɛn we de tek mɛrɛsin we de chenj ɔ stɔp di imyun sistɛm: Sɔm sik dɛn de we wi yon imyun sistɛm kin atak wi yon bɔdi. Sɔm ɛgzampul dɛn na sik dɛn lɛk multiple sclerosis, Crohn’s disease, rεumatoid arthritis, ɛn lupus. Sɔm mɛrɛsin dɛm wae dɛn kin yuse fɔ trit dɛn kayn sik ya kin mek pɔrsin gɛt PML.

Aw fɔ no di sik kɔrɛkt wan?

If yu dɔktɔ sɔspɛkt PML bay di sayn dɛm we yu gɛt, i go tɛl yu fɔ du sɔm tɛst dɛm.

1. MRI skan we dɛn kin du:Dis na di tɛst we impɔtant pas ɔl. MRI mashin kin tek rili klia, ditayli pikchɔ dɛn bɔt di bren. i kin si klia wan di εria dεm (lεsin dεm) usay di maylin na di bren dεn dכn pwεl bay PML.

. Dɛn kin tɛst dis wata fɔ si if di JC vayrɔs de.

3. Bren Bayopsi: Dɛn nɔ kin du dis, ɛn na if ɔda tɛst dɛn nɔ kin kɔmɔt fayn. Insay dis, dɛn kin ɔpreshɔn wan rili smɔl pat pan di tisu na di bren ɛn chɛk am wit maykroskɔp.

Aw dɛn kin trit PML?

Di tin we impɔtant pas ɔl fɔ trit PML na fɔ trit di kɔndishɔn we mek yu imyun sistɛm wik.

• Lɛ wi se yu gɛt PML bikɔs ɔf HIV. Dɔn yu nid fɔ yuz antiretroviral therapy (anti-HIV drugs) kɔrɛkt wan ɛn bil yu imyuniti bak.
• If yu gɛt PML bikɔs ɔf wan mɛrɛsin we de mek yu nɔ gɛt di sik, yu fɔ tɔk to yu dɔktɔ wantɛm wantɛm fɔ disayd if yu fɔ stɔp ɔ chenj di mɛrɛsin.
• Sɔntɛnde, dɛn kin yuz wan tritmɛnt we dɛn kɔl plasma exchange fɔ pul dɛn mɛrɛsin ya we de mek di bɔdi nɔ gɛt bɛtɛ trɛnk na di blɔd. dis de gi di imyun sistεm di trεnk fכ fכt di JC vayrus bak.

Risach stil de go bifo pan mɛrɛsin dɛm we de wok agens di JC vayrɔs sɛf, bɔt dɛn nɔ dɔn fɛn ɛni mɛrɛsin we go wok fayn yet.

Bɔt i sɔri fɔ no se di wayt tin ɔ maylin na di bren we di vayrɔs dɔn pwɛl nɔ kin kam bak. So, ivin afta di sik dɔn dɔn, sɔm sayn dɛm (e.g., yu nɔr de fil fayn, yu nɔr de mɛmba fayn) kin de fɔ ɔl yu layf. Dis kin tan lɛk di tin dɛn we kin apin we pɔsin gɛt strok fɔ lɔng tɛm.