Yu dɔn ɛva tink se difrɛn kayn tumbu kin kam insay wi kidni? Sɔntɛnde, dɛn kin si dɛn tumbu ya bay aksidɛnt we dɛn de du tɛst fɔ ɔda tin we nɔ gɛt ɛni sayn. fכ egzampl, wan kayn tכmכro we de divεlכp na di kidni, bכt bכku tεm nכ de kεnsar (i.e. benign), dεn kכl am `(Renal Angiomyolipoma)` כ `(AML)`. Pan ɔl we di nem kin tan lɛk se i kɔmplikt smɔl, lɛ wi tɔk bɔt am simpul wan, di we we yu go ɔndastand.
Wetin na dis `(Rεnal Angiomyolipoma)` כ `(AML)`?
Fɔ tɔk am simpul wan, Renal Angiomyolipoma na wan tumbu we de divɛlɔp na yu kidni. di bεst pat na dat bכku pan dεn tכmכro dεm ya nכto kansa (benign) . Dis min se i nɔ go izi fɔ mek dɛn kɔz ɛni big prɔblɛm. Bɔt nɔ kin apin so ɔltɛm, dɛn tumbu ya kin brok ɛn mek blɔd kɔmɔt , we kin rili siriɔs, ɛn sɔntɛnde i kin ivin mek pɔsin in layf de pan denja.
Naw yu kin de wɔnda, "Wetin i min fɔ gɛt tumbu?" Wi bɔdi gɛt sɛl dɛn we de sheb ɛn gro nɔmal wan fɔ mek wi bɔdi kɔntinyu fɔ de. Bɔt sɔntɛnde, dɛn sɛl ya kin bigin fɔ gro we dɛn nɔ ebul fɔ kɔntrol ɛn dɛn kin gro pasmak . Na da tɛm de wan tumbu kin fɔm. dis tכmכro we dεn kכl `(Renal Angiomyolipoma)` na tri men pat dεm:
- Blɔd vesel dɛn
- Mɔsul sɛl dɛn
- ɛn fat sɛl dɛn (fat) .
Dɛn tri tin ya kin kam togɛda fɔ mek dis spɛshal frut.
Aw kɔmɔn dis kɔndishɔn we dɛn kɔl `(AML)`?
infakt, dis na di kayn tכmכro we kכmכn pas כl we nכ gεt bεnεs (nכn kεnsar) kidni tכmכro. Fɔ sho se dis sik kin afɛkt bitwin 2 ɛn 6 pan ɛvri 1,000 pipul dɛn . I kin apin mɔ pan uman dɛn we dɔn pas 50. So if yu na uman we de na dis ej grup, i fayn fɔ mek yu no bɔt dis.
Dis `(Renal Angiomyolipoma)` gɛt fɔ du wit ɔda sik dɛn?
Yes, sכmtεm dεn kin si dis `(Renal AML)` kכndyushכn tכgeda wit sεvεra כda hεlth prכblεm dεm. dat min se, wan sכm tεndens de fכ dεn `(AML)` tכmכro dεm fכ divεlכp bitwin pipul dεm we gεt dεn sik dεm de. Sɔm pan dɛn kayn sik ya na:
- Lymphangioleiomyomatosis (LAM) - Dis na sik we nɔ kin apin so ɔltɛm we kin afɛkt di lɔng dɛn mɔ.
- Nyurofibromatosis tayp 1 - dis na jεnεtik kכndishכn we de mek tכmכro dεm na di nεv sεstem.
- Tuberous Sclerosis Complex (TSC) - Dis na jεnεtik kכndyushכn bak. Benign tumor dεm de divεlכp na difrεn pat dεm na di bכdi, lεk di bren, kidni, at, lכng, εn skin. AML tumor dεm dεn kin si bak wit dis kכndyushכn.
- `(von Hippel-Lindau disease)` - Dis na jεnεtik kכndishכn bak, we kin mek tכmכro dεm εn sist dεm we fulכp fכ fכm na difrεn כgan dεm.
So, if yu gɛt dis kɔndishɔn, dɔktɔ dɛn go luk fɔ `(AML)` bak.
Wetin mek dis `(Rεnal Angiomyolipoma)` de divεlכp? Wetin na di kɔz?
Di men rizin fɔ dis na wiWe pɔsin chenj wan jin, dɛn kɔl am jɛnɛtik muteshɔn. fכ bi prεsis, dis chenj de apin insay tu jin dεm we dεn kכl `(TSC1)` כ `(TSC2)`. dεn kכl dεn jin dεm ya "tumor suppressor genes" . Dat min se di wok we dɛn jin ya de du na fɔ kɔntrol di we aw wi sɛl dɛn de gro we wi nɔ want.
dis `(TSC)` jin de mek wan protin we dεn kכl tuberin . dis protin de εp fכ kכntrכl di growth εn saiz fכ di sεl dεm. So, imajin, wetin kin apin if mכtεshכn כ chenj de na dis `(TSC)` jin? afta dat di prodakshכn fכ di tuberin protin de disrupt. afta dat di signal fכ "stכp" di sεl dεm nכ de go fayn. as a rizulכt, di sεl dεm de stat fכ gro we dεn nכ de kכntro , εn leta wan tכmכro lεk `(AML)` de fכm. Yu ɔndastand?
Wetin na di simptom dɛm fɔ `(Renal Angiomyolipoma)`?
Bɔku pipul dɛn nɔ ivin no se dɛn gɛt Renal AML! Dis na bikɔs bɔku tɛm dɛn nɔ kin gɛt ɛni sayn . Dɛn kin jɔs no am bay we dɛn du di kidni tɛst (lɛk ɔltra saund skan) fɔ ɔda rizin.
כltu, sכm tεm, dis `(AML)` tכmכro kin mek yu gεt simptom dεm. sכmtεm dεn kin fכnshכn di tכmכro bikoz fכ wan kכndyushכn we dεn kכl `(retroperitoneal hemorrhage)` . Dis na tin we siriɔs smɔl. Fɔ tɔk am simpul wan, wan pat pan di tɔŋ kin brok ɛn bigin fɔ blɔd go na di say we de biɛn di bɛlɛ. Dis na imejensi ɛn i kin mek pɔsin in layf de pan denja.
Apat frɔm dat, sɔm ɔda sayn dɛn de we nɔr kin rili si:
- Anemia - Dis min se di bɔdi nɔ gɛt inof wɛlbɔdi rɛd blɔd sɛl.
- Fɔ fil pen ɔ nɔ fil fayn na yu bɛlɛ, bak, ɛn yu bɛlɛ .
- blɔd ɔ blɔd sɛl dɛn de na di urine (Hematuria) .
- Ay blɔd prɛshɔn (Hypertension) .
- Kidni failure - Dis kin rili rare.
- Fɔ fil wan lump we de fil lɛk se dɛn de kech am na di an .
- Infεkshכn na di urinary tract .
If yu gɛt wan ɔ mɔ pan dɛn sayn ya, i go fayn fɔ mek yu go to dɔktɔ.
Aw dɛn kin no dis sik `(Renal Angiomyolipoma)`?
as wi bin se, bכku tεm, dεn kin fכnshכn dεn ``AML'' tכmכro dεm ya insidεnt wan. Dɛn kin si dɛn we dɛn de chɛk dɛn bɛlɛ fɔ ɔda rizin, ɔ we dɛn de du rutin skrinin fɔ pipul dɛn we gɛt sik dɛn we gɛt fɔ du wit dis, lɛk di ``Tuberous Sclerosis'' we wi bin dɔn tɔk bɔt bifo tɛm.
Dɔktɔ kin no fɔ tru if yu gɛt renal AML bay we i du sɔm imej tɛst dɛn we de tek pikchɔ dɛn insay yu bɛlɛ :
- (CT skan) (Kɔmpyut Tomografi skan) .
- (MRI) (Magnetik Rizɔnans Imej) .
- `(Skan ɔltra sawnd)` (Skan ɔltra sawnd)
Bɔrku tɛm, wan pan dɛn imej tɛst ya kin du fɔ mek dɛn no di sik. Bikɔs dɛn Renal Angiomyolipomas ya gɛt fat, bɔku tɛm dɛn kin tan lɛk golden yɔlɔ we dɛn skan. dis tכmכro dεm kin in sayz frכm 1 cm to lεk 20 cm . di saiz we dεn kin si mכst na bכt 9 cm.
Bɔt, wetin fɔ du if sɔntɛnde di mɛdikal tim nɔ kin ebul fɔ no fɔ tru if di tumbu nɔ fayn ɔ i gɛt kansa? If na so i bi, dɛn kin se dɛn fɔ tek di kidni bayɔpsi . Dis min se dɛn kin du ɔpreshɔn fɔ pul wan smɔl pat pan di tumbu ɛn chɛk am wit maykroskɔp. Dis go ɛp fɔ no if di sɛl dɛn gɛt kansa ɔ nɔ gɛt kansa.
Wetin na di tritmɛnt dɛm fɔ `(Renal Angiomyolipoma)`?
di tritmεnt fכ `(Renal Angiomyolipoma)` kin difrεn bכku. I dipen pan bɔku tin, lɛk di saiz fɔ di tumbu, if i gɛt sayn dɛn, ɛn yu ɔl yu wɛlbɔdi. Bɔku men tritmɛnt dɛn de we yu kin pik:
1. Aktiv sɔvɛlayshɔn:
Dɛn kin kɔl dis bak "watch ɛn wet." If di Renal Angiomyolipoma smɔl (bɔku tɛm i nɔ kin rich 4 sɛntimita) ɛn nɔ gɛt ɛni sayn , yu dɔktɔ kin tɛl yu fɔ du dis. Dɛn nɔ go gi yu ɛni tritmɛnt. Bɔt dɛn go de wach yu fɔ ɛni chenj na di tɔŋ wit skan ɔltɛm .
2. Mɛrɛsin:
sכm AML tכmכro dεm de rεspכnd to wan klas dεm we dεn kכ l mTOR inhibito dεm . Dis na tεrapi dεm we dεn de tכk bכt we de tכk bכt di jin mכtεshכn. Dɛn mɛrɛsin ya kin stɔp di tumbu fɔ mek i nɔ gro ɔ mek i smɔl.
3. Ɔpreshɔn:
Di dɔktɔ kin tɛl yu fɔ du ɔpreshɔn pan dɛn kayn tin ya:
- If `(AML)` de mek yu si di sik (e.g. pen, blɔd we de kɔmɔt).
- if di tכmכro 4 sεntimita כ big pas dat (biכs di tכmכro dεm we big kin bכs εn blכd).
- If pɔsin de tink se di tumbu kin bi kansa .
- If yu na uman we dɔn rich di ej fɔ bɔn pikin (di chenj we di ɔmon chenj we yu gɛt bɛlɛ kin ridyus di risk fɔ mek di tumbu gro ɛn bɔs).
- Yu de liv na say we i nɔ izi fɔ gɛt imejensi kia ɔ fɔ fala-fala savis (bikɔs, if yu gɛt imejensi, lɛk we yu de blɔd, dɛn nid fɔ gɛt tritmɛnt kwik kwik wan).
Bɔku we dɛn de we dɛn kin yuz ɔpreshɔn fɔ trit pɔsin:
- Embolization: Dis involv fɔ blok di blɔd vesel dɛm we de gi blɔd to di tumor. Dis na wan we we rili yusful we yu de blɔd bikɔs ɔf di Renal AML.
- `(Nεfrεktכmi)` (Nεfrεktכmi): .insay dis, dεn kin pul pat כ כl di kidni we afekt.
- Partial nephrectomy ɔ Nephron-sparing surgery: Dis involv fɔ pul di tumor nɔmɔ, ɛn lɛf di wɛlbɔdi pat pan di kidni intact. Dɔktɔ dɛn kin tray fɔ yuz dis we ɛnitɛm we i pɔsibul.
- raydiofrikyuεns ablashכn: dis de yuz hכy כt fכ pwεl abnכmal tisu (tכmכro).
A kin ridyus di risk fɔ gɛt Renal AML?
fכ bi כnεst, nכtin de we wi kin du fכ mek di jεnεtik mכtεshכn dεm we de mek di divεlכpmεnt fכ `(Renal Angiomyolipoma)`. Na tin dɛn we kin apin we wi nɔ ebul fɔ kɔntrol.
Bɔt if yu gɛt ɛni wan pan di kɔndishɔn dɛn we gɛt fɔ du wit am we wi bin dɔn tɔk bɔt (e.g. Tuberous Sclerosis Complex, Lymphangioleiomyomatosis, Neurofibromatosis type 1, von Hippel-Lindau disease) , i rili impɔtant fɔ mek yu gɛt imej tɛst ɔltɛm . Dɔn, if AML dɔn divɛlɔp, dɛn kin no am kwik kwik wan . Da we de, dɛn kin bigin di tritmɛnt we dɛn nid kwik kwik wan ɛn di risk fɔ gɛt prɔblɛm dɛn kin ridyus.
If a gɛt dis sik, wetin a fɔ ɛkspɛkt?
Di gud nyus na dat bɔku pan di Renal Angiomyolipomas na smɔl tin ɛn nɔ kin mek siriɔs prɔblɛm . Bɔt smɔl pan dɛn kin bi bad bad sik ɔ dɛn kin blɔd bad bad wan. So, i impɔtant fɔ tek tɛm wach dɛn if yu gɛt Renal AML. Yu dɔktɔ go tɛl yu aw ɔltɛm yu nid fɔ du imej tɛst.
Mɛmba se AML kin kam bak ivin afta dɛn dɔn trit am. So, i rili impɔtant fɔ de tɔk to yu mɛdikal tim ɛn de chɛk yu ɔltɛm lɛk aw dɛn se.
Ustɛm a fɔ go to dɔktɔ?
If dɛn dɔn no se yu gɛt renal AML, ɔ if yu gɛt wan sik we gɛt fɔ du wit AML, i impɔtant fɔ no di sayn dɛn we de sho se yu gɛt blɔd we de kɔmɔt na yu bɔdi . If yu gɛt ɛni wan pan dɛn sik ya, go to dɔktɔ wantɛm wantɛm :
- If blɔd de na yu urine.
- If yu gɛt pen we nɔ de dɔn, we nɔ de stɔp na yu bɛlɛ we de ɔp ɔ yu hip eria.
- If yu si sayn dɛm fɔ shok:
- Kɔnfyus
- Di at rit kwik kwik wan
- Diziz we pɔsin kin gɛt
- Shalo brith we yu de blo
- Pale skin
If yu si sɔntin lɛk dis, nɔ delay.
Fɔ dɔn, wetin fɔ mɛmba (Take-Home Message) .
Okay, so di `(Renal Angiomyolipoma)` כ `(AML)` we wi bin de tכk bכt na tכmכro we de fכm na di kidni, εn i kin bi nכn-kansa (benign).. Bɔrku tɛm, dis kin bi bay chans, wae dɛn de du ɔda tɛst. If dɛn dɔn no se yu gɛt dis kayn `(Renal AML)`, nɔ panik . Tɔk to yu dɔktɔ fɔ disayd us tritmɛnt ɔ monitarin we go fayn fɔ yu.
Di tin we impɔtant pas ɔl na fɔ wach dɛn tumbu ya ɔltɛm . If yu du dat, yu go mek wan siriɔs sik lɛk fɔ blɔd nɔ kam. Bikɔs if sɔntin lɛk dat apin, i kin mek pɔsin in layf de pan denja. So, fala wetin yu dɔktɔ tɛl yu ɛn du tɛst di rayt tɛm. Yu wɛlbɔdi de na yu an!
👩🏽 ⚕️ Ɔda kwɛstyɔn dɛn (FAQ dɛn)
💬 Yu tink se Renal Angiomyolipoma na kidni kansa?
Nɔ! dis na di tכmכro we kכmכn pas כl, bכt nכto kεnsar (benign) tכmכro we de fכm na di kidni dεm. as di nem sho, dis tכmכro de fכm bay di kכmbaynshכn fכ di bכdi vεsul dεm (Angio), mכsul dεm (Myo), εn fεt/כyl (Lipo). I nɔ de ɛva skata to ɔda pat dɛn na di bɔdi.
💬 Dis no bi problem ivin as no bi kansa?
If dis tumbu smɔl pas 4 sɛntimita (dayamita), no prɔblɛm nɔ de, ɛn di pɔsin nɔ kin ivin fil se i de. Bɔt we di tumbu gro, di blɔd vesel dɛn we de insay am kin bɔs ɛn blɔd kin bigin fɔ flɔ insay di kidni wantɛm wantɛm (blɔd kin kɔmɔt insay), ɛn dis kin mek i fil bad bad wan ɛn ivin day.
💬 If di tumor big, a nid fo kot di ohl kidni en komot am?
Trade, dɛn bin de pul di wan ol kidni. Bɔt naw nyu we dɛn de fɔ sev di kidni. wan tכb de pas tru di leg εn di vein we de gi bכdi to di tכmכro de blכk (embolization), we de mek di tכmכro shrink insεf. כ, na di pat pan di tכmכro we de de nכmכ dεn de kכl (partial nephrectomy).
` Rεnal Angiomyolipoma, AML, Kidni Tכmכr, Kidni Sik, Tuberous Sklerosis, Kidni Blidin, Jεnεtik Mכtεshכn
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