I at fɔ put insay wɔd wetin yu kin fil we yu kam fɔ no se yu gɛt kansa. Bɔt we di dɔktɔ tɔk bɔt tritmɛnt ɛn yu yɛri wɔd dɛn lɛk ‘kimotɛrapi’, i nɔmal fɔ mek yu fil mɔ fred, want fɔ no mɔ, ɛn kɔnfyus. Wan pan di kemo drɔgs we dɛn kin yuz fɔ mɛn kansa na ‘Taxane.’ Tide, wi go tɔk bɔt dis simpul wan, di we we yu go ɔndastand, lɛk se yu de tɔk to yu tayt padi.
Wetin na Taxane rili?
Fɔ tɔk am simpul wan, taksan na wan klas ɔf kemotɛrapi drɔgs we de kil kansa sɛl dɛn ɛn stɔp di tumor dɛn we de gro. Kimotɛrapi min fɔ ad dɛn mɛrɛsin ya to wi blɔd, we de travul ɔlsay na di bɔdi fɔ fɛn ɛn pwɛl kansa sɛl dɛn.
Wetin mek dɛn taxane drɔgs ya spɛshal na bikɔs dɛn kɔmɔt na tik dɛn bay dɛnsɛf. Dɛn bin fɔs pul dɛn frɔm di bark fɔ di ‘Yew’ tik . Infakt, taksan na wan pan tu kayn kemo drɔgs we dɛn kin pul frɔm plant. di כda kayn na wan grup fכ dכg dεm we dεn kכl ‘Vinca alkaloids’, we kכmכt frכm di ‘Mella’ plant.
Naw, sayɛnsman dɛn de stɔdi di kemikal strɔkchɔ fɔ di taksan dɛn we dɛn kin gɛt frɔm dɛn plant ya ɛn dɛn de ivin wok fɔ mek dɛn sintetik wan na lɛbɔretri.
Aw dis mɛrɛsin de kil di kansa sɛl dɛn?
Fɔ ɔndastand dis, wi nid fɔ ɔndastand fɔs aw di kansa sɛl dɛn kin skata. Kansa kin skata bay we i sheb wan kansa sɛl to tu, we insɛf kin sheb to 4, dɔn i kin bɔku kwik kwik wan. Insay mɛrɛsin, di we aw wan sɛl de sheb to tu, dɛn kɔl am maytosis .
wetin taksan dכg dεm de du na fכ intafεr di prכsεs we di sεl dεm de sheb.
Imajin se we wan sɛl sheb, di jɛnɛtik tin we de insay da sɛl de fɔ sheb to tu ɛn sɛn am to di tu nyu sɛl dɛn. strכkchכ dεm de insay di sεl we de εp fכ dis wok, lεk sכm sכm kebul tay. Dɛn kɔl dɛn tin ya maykrotubul dɛn . Na dɛn tin ya de pul di pat dɛn we dɛn nid fɔ mek di tu nyu sɛl dɛn kɔmɔt.
we dεn tek di taksan dכg insay di bכdi, i de mek dεn kεbul dεm ya we dεn kכl maykrotubul stif we nכ nid . Dɔn dɛn nɔ kin ebul fɔ fol ɔ opin fayn fayn wan. So, di we aw dɛn kin sheb di sɛl to tu kin stɔp af-af. we dis divεlכpmεnt nכ kin bi, di mama εn papa sεl de day afta sכm tεm.
Taxane drɔgs de kɔntrol kansa bay we dɛn de pwɛl di abiliti we di kansa sɛl dɛn gɛt fɔ sheb ɛn gro.
Us kayn kansa dɛn kin yuz taxane drɔgs fɔ?
Taxanes na wan rili impɔtant klas fɔ drɔgs we dɛn kin yuz fɔ trit bɔku bɔku kansa dɛn. Sɔm pan dɛn tin ya dɛn kin yuz as fɔs layn tritmɛnt fɔ sɔm kansa dɛn, ɛn ɔda wan dɛn kin yuz fɔ kansa dɛn we dɔn pas ɔlsay.
| Tayp dɛm fɔ kansa we dɛn trit wit Taxane | |
|---|---|
| Di men wan we dɛn kin yuz kansa | |
| Kansa na ovarian | Brɔst kansa |
| Ɔda kayn kansa we dɛn kin trit | |
| Blada kansa | Kansa na di sɛvikal |
| Kansa we de na di bɛlɛ | Kansa na ed ɛn nɛk |
| Prɔstat kansa | Lɔng kansa (Nɔn-smɔl sɛl lɔng kansa) . |
| Kansa na di uterin | Limfoma we dɛn kɔl Limfoma |
Sɔntɛnde, dɛn kin gi taksan wit ɔda kemotɛrapi drɔgs. Yu dɔktɔ go disayd us tritmɛnt go fayn fɔ yu sik.
Aw dɛn kin gi dis tritmɛnt? Ɛn wetin na di bad tin dɛn we kin apin to am?
Aw dɛn kin gi di tritmɛnt
Dɛn kin gi taksan insay di bɛlɛ (IV) . Dɛn kin gi dɛn tru wan kanula (kateta), we fiba salin sɔlvushɔn. Dis tritmɛnt kin tek wan awa ɔ sɔm awa. Yu kin nid fɔ gɛt dis tritmɛnt wan tɛm insay di wik, ɔr wan tɛm ɛvri sɔm wik. Yu dɔktɔ go disayd aw fɔ trit yu bay aw yu de fil.
Di sayd ɛfɛkt dɛn we dɛn kin si bɔku tɛm
Pan ɔl we di mɛrɛsin dɛn we dɛn kin yuz fɔ kimotɛrapi kin tɔch di kansa sɛl dɛn we de sheb kwik kwik wan, sɔntɛnde dɛn kin afɛkt di sɛl dɛn we gɛt wɛlbɔdi ɛn we kin sheb kwik kwik wan na wi bɔdi bak. Fɔ ɛgzampul, tin dɛn lɛk wi ia fɔlikul sɛl, skin sɛl, ɛn blɔd sɛl. Dis na di rizin we mek sayd ɛfɛkt kin apin.
| Sayd Ifɛkt we i kin gɛt | Wan simpul ɛksplen |
|---|---|
| Nyutropenia we pɔsin kin gɛt | di nyutrofil dεm we de dכn, we na wan kayn wayt blכd sεl we de fכt infεkshכn na di bכdi, we de mek di risk fכ gεt infεkshכn bכku. |
| Nyuropathy we de na di periferik | Di nerve damej na di an ɛn leg. Dis kin mek yu an ɛn fut nɔ gɛt bɛtɛ trɛnk, pen, ɔ wik . |
| Di ia we de lɔs | Dis na kɔmɔn sayd ɛfɛkt, bɔt di ia go gro bak afta di tritmɛnt dɔn. |
| Vɔmit ɛn nɔs | I kin kɔmɔn insay di de dɛn we dɛn de trit am. Dɛn kin gi mɛrɛsin fɔ kɔntrol dis. |
| Mɔsul ɛn jɔyn pen | I kin gɛt pen na di bɔdi ɛn di jɔyn dɛn kin stif. |
| Blɔd prɛshɔn kin chenj | Blɔd prɛshɔn kin go ɔp ɔ dɔŋ. |
| Di blɔd sɛl dɛn we de go dɔŋ | we di rεd bכdi sεl dεm dכn dכn kin mek yu gεt anemia εn if di pletlεt dεm dכn (thrombocytopenia) i kin mek i gεt risk fכ bכn. |
Dɛn sayd ɛfɛkt ya nɔ kin apin to ɔlman. Dɔn bak, wi kin ebul fɔ kɔntrol bɔku pan dɛn. I rili impɔtant fɔ tɛl yu dɔktɔ ɔr nɔs wokman dɛm bɔt ɛni diskɔmfɔt we yu fil.
Ɛni risk de fɔ dis tritmɛnt?
Taxanes na wan tritmɛnt we rili woke we dɔn mek di wan dɛn we gɛt kansa liv lɔng. Bɔt lɛk ɔl di tritmɛnt dɛn, sɔm prɔblɛm dɛn de we kin mek pɔsin gɛt prɔblɛm.
Sɔntɛnde, de sayd ɛfɛkt wae wi dɔn tɔk bɔt kin siriɔs. If na so i bi, yu dɔktɔ kin disayd fɔ chenj yu tritmɛnt schedule ɔ stɔp am fɔ sɔm tɛm.
Wan ɔda impɔtant tin na dat as tɛm de go, di kansa sɛl dɛn kin bigin fɔ ‘yuz to’ dis mɛrɛsin. Dat min se dɛn kin gɛt kemoresistɛns . Dɔn di tin we di drɔg de du kin go dɔŋ. Bɔt if dat apin, yu dɔktɔ go tɔn to tin dɛn lɛk fɔ tray fɔ tek ɔda mɛrɛsin ɔ fɔ tɛl yu difrɛn tritmɛnt we yu go yuz.
Mɛsej we dɛn kin kɛr go na os
- Taxane na wan rili pawaful klas fɔ kemotɛrapi drɔgs we dɛn kin pul frɔm plant dɛn we kin stɔp di kansa sɛl dɛn fɔ sheb.
- Dis kin trit bɔku kayn kansa fayn fayn wan, lɛk di bɔdi, di ovarian, ɛn di lɔng.
- Sɔm sayd ɛfɛkt lɛk we yu ia de lɔs, yu bɔdi nɔ de fil fayn, ɛn yu bɔdi de at, bɔt yu kin ebul fɔ kɔntrol bɔku pan dɛn.
- I rili impɔtant fɔ tɛl yu dɔktɔ ɔ nɔs bɔt ɛni smɔl prɔblɛm we yu fil we yu de trit yu.
- Kansa tritmɛnt na wan joyn. Mɛmba ɔltɛm se nɔto yu wan de pan dis waka ɛn yu gɛt wan tim we sabi du mɛrɛsin fɔ ɛp yu.
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