Yu kɔlon gɛt pɔyzin bad bad wan? (Toxic Megacolon) Lɛ wi lan bɔt am.

Yu dɔn ɛva gɛt bad bad bɛlɛ, yu bɔdi de blo, ɛn yu bɔdi nɔ de fil fayn ɔltɛm? Sɔntɛnde, dis kin bi di biginin fɔ wan big prɔblɛm. Tide wi go tɔk bɔt wan sik we siriɔs smɔl, bɔt i kin mɛn if dɛn no am kwik. Dat na in dɛn kɔl `(Toxic Megacolon)`. Di nem de mek yu fred smɔl, nɔto so? Bɔt lɛ wi ɔndastand dis simpul wan.

Wetin na `(Toxic Megacolon)`? Fɔ tɔk am simpul wan...

Fɔ tɔk am simpul wan, `(Toxic Megacolon)` na wan rili siriɔs, imejensi kɔndishɔn we kin apin na yu big intestin (dɛn kin kɔl am bak `(Colon)`). i kin kכz fכ siriכs inflameshn, dat na, swel כ injuri (`(Colitis)`) na di big intestin.

Tink bɔt dis we: wi big intestinal tan lɛk tyub we kin chenj. I gɛt wan tint mɛmbran insay. Bɔrku tɛm, we yu gɛt kɔlayt, i kin afɛkt dis mɛmbran. Bɔt if di inflamɛns rili bad, i kin go na di dip layt dɛn na di insay, dat na di mɔsul dɛn we de na di wɔl dɛn na di insay.

Wetin kin apin we dis kin apin? di mכsul dεm na di wכl dεm na di intestinal dεm stכp fכ wok fayn fayn wan. na dεn mכsul dεm ya de push it εn briz dכn na di intestinal dεm. We dɛn stɔp fɔ wok, it ɛn briz kin trɔp insay di insay. Dɔn di wɔl dɛn na di insay kin wik, strɛch, ɛn pan. Dɛn kin ful-ɔp lɛk balyɔn. Di tin we denja pas ɔl na dat di dɔti tin dɛn we kin gɛda dis we kin mek pɔyzin ɛn lik tru dɛn wɔl dɛn we wik ɛn go insay di blɔd. Dɔn di wan ol bɔdi kin bigin fɔ gɛt pɔyzin. Wi kin kɔl dis pɔyzin mɛgakolon ɔ ``Toxic Megakolon``.

Wetin na di difrɛns bitwin `(Toxic Megacolon)` ɛn ɔda kayn `(Megacolon)`?

Naw yu kin de tink se, "Nɔto ɔda sik dɛn de we kin mek di kɔlon swel?" Yɛs, dɛn de. sכmtεm di kכlon kin swεla bikoz fכ tin dεm we de ambɔg (`(Obstructions)`), כ sכmtεm dεn nכ de nכ gεt εni tin we de ambɔg am (`(Pseudo-obstructions)`). Dɛn kin kɔl dis bak `(Megacolon)`.

כltu, di spεshal tin fכ `(Toxic Megacolon)` na dat, lεk aw wi bin dכn tכk, di pכyzin de spre כlsay na di bכdi (`(Systemic Toxicity)`) . Dis nɔ kin apin ɔltɛm na ɔda kayn `(Megacolon)`. patikyular, dεn kin si dis tכxik kכndyushכn mכst wit `(Colitis)` we kin apin wit inflameshn na di intestinal (`(Colitis)`, dat na, bikoz fכ difrεn infεkshכn dεm כ `(Inflammatory)` kכndishכn dεm.Na we di simptom dεm lεk lכw bכdi prεshכn, at bit kwik, εn kכnfyushכn de sho.

Wetin na di siriɔs kɔmplikeshɔn dɛm we kin apin bikɔs ɔf `(Toxic Megacolon)`?

Dɛn kin tek dis as mɛdikal imejensi , bikɔs i kin mek pɔsin gɛt bɔku siriɔs prɔblɛm dɛn we kin mek pɔsin in layf de pan denja.

• Gastrointestinal perforation / rupture : Wetin a de se na dat di wol dεm na di intestin de wik εn strεch. We dat apin, i kin izi fɔ brok ɔ bɔs.
• Sivɛri blɔd we de kɔmɔt na di bɛlɛ ɛn blɔd we de lɔs : Di intestinal kin wund ɛn i kin blɔd bɔku.
• Sistem infεkshכn εn sεpsis: We di tכxin dεm we de kכmכt na di intestines go insay di bכdi, di infεkshכn kin spre כlsay na di bכdi, we kin mek i gεt wan denja kכndyushכn we dεn kכl sepsis.
• Abdominal compartment syndrome: we di prεshכn we de insay di bכdi de go כp kin afekt כda כgan dεm.

I rili impɔtant: If yu gɛt sayn dɛn lɛk dis, di bɛst tin fɔ du na fɔ go to dɔktɔ ɛn nɔ de te.

Aw Toxic Megacolon kin ivin mek pɔsin day?

Dis na siriɔs tin. As wi bin dɔn tɔk, di wɔl dɛn na di kɔlon we wik ɛn strɛch kin rɔtin izi wan ɛn gɛt pɔt. If dis kayn perforeshɔn apin, bad bad blɔd kin kɔmɔt insay di bɛlɛ, ɛn tin dɛn lɛk fes kin lik insay di bɛlɛ, we kin mek infɛkshɔn insay di bɛlɛ (peritonitis). Dis infekshɔn kin gɛda kwik kwik wan na di blɔd ɛn pɔyzin di wan ol bɔdi, we kin mek pɔsin gɛt wan sik we dɛn kɔl pɔyzin shɔk. Dɔn bak, we di prɛshɔn we de insay di bɛlɛ go ɔp tumɔs, di blɔd kin flɔ to ɔda impɔtant ɔgan dɛn (lɛk di kidni ɛn di lɔng) nɔ kin wok fayn, ɛn dɛn kin nɔ gɛt ɔksijɛn ɛn dɛn nɔ kin wok fayn. Dis na di men tin we kin mek pɔsin day.

Wetin na di sayn dɛm fɔ `(Toxic Megacolon)`?

We dis kayn tin kin apin, difrɛn kayn sayn dɛn kin sho. Sɔm pan dɛn kin fil lɛk se na nɔmal bɛlɛ de at. Bɔt if yu gɛt pas wan pan dɛn sayn ya, ɔ if dɛn tranga, yu fɔ wɔri.

• Daya (bɔku tɛm blɔd kin kɔmɔt) : Kɔntinyu fɔ muv yu bɔdi, ɛn if blɔd de kam wit am, dat na sayn we denja.
• Bεlε pen εn tεndεns : Pen wae de fil lεk se dεn de sכk yu bεlε, εn i de at ivin we yu tכch am.
• Distended abdomen : di bכdi de big, lεk se i fulכp wit briz.
• Flatulens ɛn gas pen (`(Gas ɛn gas pen)`) : Di bɛlɛ ful-ɔp wit gas, we de mek yu fil pen.
• Nɔs ɛn vɔmit : Fɔ fil sik to yu bɛlɛ, fil lɛk se yu go vɔmit.
• Diziz (`(Diziz)`)
• Dihaydreshɔn : Wata de lɔs na di bɔdi. Di sayn dɛm na we yu mɔt dray ɛn yu nɔ de pis.
• Rapid at rate : Na di rit we di at de bit de go ɔp.
• Fiva (`(Fiva)`)
• Lכw bכdi prεshכn (`(Lכw bכdi prεshכn)`) : Na di prεshכn we de dכn.
• Mental kɔnfyushɔn : Nɔr kin ebul fɔ ɔndastand wetin de apin, fil fɔ kɔnfyus.
• Fatigue/malaise : Na filin fɔ wikɛd.

Wetin na di men tin we kin mek pɔsin gɛt `(Toxic Megacolon)`?

Infakt, ɛni kayn siriɔs kɔlayt kin mek pɔyzin mɛgakolon. Bɔt bɔku tɛm, na wan sik we dɛn kɔl inflammatory bowel disease (IBD) kin kam wit am.Inflammatory bowel disease (IBD) na wan jεnarכl tεm fכ sεvεra kayn kolεt dεm we de kכlכs, we min se dεn kin las fכ lכng tεm εn i at fכ trit. Fɔ ɛgzampul, Ulcerative Colitis ɛn Crohn’s Disease de ɔnda dis kategori. If dɛn nɔ kɔntrol dɛn kɔndishɔn ya fayn fayn wan wit it ɛn mɛrɛsin, dɛn kin dɔn afɛkt di dip layers na di kɔlon, we kin mek i gɛt Tɔxik Mɛgakolon.

Wetin na ɔda tin dɛn we kin mek pɔsin gɛt Toxic Megacolon?

`(Toxic Megacolon)` na wan kɔmplikɛshɔn we de mek pɔsin gɛt siriɔs `(Colitis)`. So bɔku tin kin de fɔ dis `(Colitis)`. dat min se, `(Toxic Megacolon)` kin kכz difrεn kayn `(Colitis)` kכndishכn dεm. Lɛ wi si wetin dɛn bi:

• Ulcerative Colitis : Dis na di kayn IBD we kɔmɔn pas ɔl ɛn na in bak na di men tin we kin mek pɔsin gɛt Tɔxik Mɛgakolon. Bɔku tɛm, Toxic Megacolon kin apin insay di fɔs sɔm ia afta dɛn dɔn no se i gɛt am.
• Crohn’s Disease : Dis na ɔda kayn IBD. I kin afɛkt di smɔl intestin mɔ, bɔt i kin afɛkt di big intestin bak. Pipul wae gɛt Crohn’s Disease kin gɛt risk bak fɔ gɛt Toxic Megacolon ali na di sik.
• Ischemic Colitis : We di intestinal nɔ de gi blɔd fayn fayn wan (Intestinal Ischemic Syndrome), dis kin mek yu gɛt Ischemic Colitis. Dis kin tranga smɔl fɔ trit, ɛn i kin go bifo to Toxic Megacolon.
• Radiation Colitis : Radiation therapy fɔ sik dɛm lɛk kansa kin mek yu gɛt shɔt tɛm colitis as sayd ɛfɛkt. Bɔt pan sɔm pipul dɛn, i kin de fɔ lɔng tɛm ɛn mek prɔblɛm dɛn.
• Infεkshכn Kolayt : Baktri, parasayt, כ vayral infεkshכn kin mek yu gεt kolεt. Sɔm kayn infɛkshɔn kin afɛkt sɔm pipul dɛn. Ivin simpul it pɔyzin ɔ bɛlɛ flu kin mek sɔm pipul dɛn gɛt siriɔs kɔlayt. Pipul wae gɛt wik imyun sistɛm kin de pan risk fɔ gɛt infεkshɔn lɛk saytomegalovayrɔs.
• Pseudomembranous Colitis : Dis na wan kayn infεkshכn kolεtis we di baktri we de kכlכs we dεn kכl Clostridium difficile (C. diff) de kכz. Bɔku tɛm dɛn kin kɔl am bak as risk factor fɔ pɔyzin megakolon. Bɔrku tɛm e kin apun pan pipul dɛm wae de tek antibayɔtik fɔ ɔda infekshɔn. dis na biכs we di gud baktri dεm na di intestinal dεn kil dεm wit antibaytik, di C. diff baktri dεm kin bigin fכ gro aut כf kכntrol. Dis C. diff infεkshכn kin bi siriכs kwik kwik wan.

Wetin na di risk factor dɛm fɔ divɛlɔp `(Toxic Megacolon)`?

Sɔm pipul dɛn kin gɛt dis sik. Udat dɛn na dɛn?

• Pipul wae gɛt `(Inflammatory Bowel Disease (IBD))`.
• Pipul dεm we gεt כtoimyun sik dεm (i.e. sik dεm we di imyun sistεm de atak di bכdi in כwn sεl dεm)
• Pipul dɛn we gɛt `(HIV/AIDS)`.
• Pipul dɛn we dɔn gɛt ɔgan transplant ɔ we de tek immunosuppressants.
• Pipul dɛn we gɛt dayabitis.
• Pipul dɛn we gɛt sik na dɛn kidni.
• Pipul wae gɛt krɛse sik (Kronik Obstruktiv Pulmonary Disease - COPD).
• Pipul dεm wae gεt hat kכndyushכn (`(Congestive Heart Failure)`).

Dɔn bak, sɔm mɛrɛsin dɛn we yu kin tek kin mek dis sik (Toxic Megacolon) wɔs:

• Di kayn mɛrɛsin dɛn we dɛn kin yuz fɔ mɛn pen (`(Opioids)`)
• Nכn-stεroyd anti-inflammatory drכg dεm (NSAID dεm - fכ egzampl Ibuprofen, Diclofenac) .
• Sɔm mɛrɛsin fɔ pwɛl hat (`(Antidepressants)`)
• Antikolinɛrijik dɛn
• Antidiarrheals (yuz dɛn wan ya wit kɔt, bikɔs dɛn kin mek di kɔndishɔn wɔs bay we dɛn de blok di bɔdi we de muv) .
• Bowel prep (mɛrɛsin we dɛn kin gi fɔ klin di bɛlɛ bifo dɛn du kɔlon skɔpi) (Dis kin denja fɔ pɔsin we dɔn ɔlrɛdi gɛt kɔlayt)

Aw dɛn kin no di sik we dɛn kɔl Toxic Megacolon?

Dɔktɔ go aks yu bɔt yu sik dɛn, ɛni sik we yu bin gɛt trade, ɛn ɛni mɛrɛsin we yu bin de tek. Dis infɔmeshɔn impɔtant bikɔs sɔm sik ɔ mɛrɛsin kin mek yu gɛt Toxic Megacolon. Sɔm mɛrɛsin dɛm lɛk stɛroyd kin stɔp bak di sayn dɛm fɔ Toxic Megacolon. Dɔn di dɔktɔ go du yu bɔdi ɛgzam.

We yu de chɛk yu bɔdi, yu dɔktɔ go chɛk fɔ si if yu bɛlɛ dɔn swel, yu gɛt sɔri-at, ɛn yu nɔ de fil fayn. Dɛn kin yuz stetɔskɔp bak fɔ lisin if di bɔdi nɔ de muv igen. Dɛn go chɛk yu impɔtant sayn dɛm (puls, tɛmpracha, ɛn blɔd prɛshɔn) fɔ si if yu gɛt sayn dɛm we de sho se yu gɛt pɔyzin, lɛk fiva, blɔd prɛshɔn we de dɔŋ, ɛn at rit kwik kwik wan.

pan tap dat, dεn kin nid fכ du bכdi tεst εn bכdi imej tεst (e.g., εks-ray, bכdi כltra saund, כ CT skan) fכ kכnfכm di diagnosis. dis imej tεst dεm de luk aw di kכlon dilayt εn if εni כda kכmplikεshכn de. Blɔd tɛst kin chɛk di nɔmba fɔ di wayt blɔd sɛl ɛn rɛd blɔd sɛl, ɛn i kin no if bad bad inflamɛns de.

Bɔku krayteria dɛn de we dɛn kin yuz fɔ no if pɔsin gɛt `(Toxic Megacolon)`:

• Pruf fɔ se di kɔlon waid pas 6 sɛntimita.
• Fɔ gɛt at le tri pan dɛn kwaliti dɛn ya:
• Fiva we pas 100.4 Fahrenheit (38 Sɛlshiɔs).
• di at rit we pas 120 bit pan wan minit.
• Di wayt blɔd sɛl dɛn we de bɔku.
• Anemia (we di rɛd blɔd sɛl dɛn nɔ bɔku).
• Fɔ gɛt at le wan pan dɛn kwaliti dɛn ya:
• Dihaydreshɔn (`(Dihaydreshɔn)`).
• Ilektrolayt/fluid imbalans.
• Altered mental stetmɛnt.
• Lɔw blɔd prɛshɔn (`(Lɔw blɔd prɛshɔn)`).

Apat frɔm dat, di dɔktɔ kin want fɔ tɛst yu blɔd ɔ yu stɔl fɔ si if ɛni patikyula infekshɔn de.

Wetin na di tritmɛnt dɛm fɔ `(Toxic Megacolon)`?

Dis sik kin nid fɔ gɛt tritmɛnt fɔ sɔm dez na ɔspitul. Di gol fɔ di fɔs tritmɛnt na fɔ mek yu kɔndishɔn stebul ɛn fɔ ridyus di kayn we aw di kɔlayt de tranga. If yu gɛt wan sik lɛk sepsis, yu kin nid tritmɛnt na di intensiv kia yunit (ICU). Fɔ ɛgzampul, mɛkanikal ventileshɔn fɔ mek yu gɛt prɔblɛm wit yu brith ɔ dayalaysis fɔ mek yu kidni nɔ wok fayn.

If nɔto dat, dis na di ɔspitul fɔs tritmɛnt fɔ `(Toxic Megacolon)`:

• IV fluid : Trit di wata we de kɔmɔt na di bɔdi ɛn balans ilɛktrɔlayt dɛn.
• Antibayɔtik : Trit infɛkshɔn if i de ɔ mek infɛkshɔn nɔ apin.
• `(Corticosteroids)` : Na wan kayn mɛrɛsin we dɛn kin gi fɔ ridyus inflamɛns (swelling).
• Bowel rεst : εnteral nyutrishכn / Tiub fכ it.

If kɔtikosterɔyd nɔ mek di sik bɛtɛ, di dɔktɔ kin yuz ɔda kayn mɛrɛsin lɛk wan mɛrɛsin we de chenj di we aw pɔsin de fɛt di sik. Dɛn tin ya kin ɛp fɔ ridyus di imyun sistɛm in ɔva riakshɔn, we kin mek di bɔdi inflamɛns pasmak ɛn di wayt blɔd sɛl dɛn na di tisu dɛn go bɔku.

Ɔpreshɔn

Na lɛk 50% pan di sik pipul dɛn nɔmɔ kin wɛl wit mɛrɛsin. Ɔda pipul dɛn kin nid fɔ gɛt ɔpreshɔn, mɔ if prɔblɛm dɛn de we go mek dɛn day. We dɛn de trit pɔsin we gɛt pɔyzin mɛgakolon, bɔku tɛm dɔktɔ dɛn kin tɔk to dɔktɔ dɛn we de du ɔpreshɔn kwik kwik wan fɔ ɛp fɔ disayd fɔ du sɔntin. Sɔntɛnde, di dɔktɔ kin disayd se i bɛtɛ fɔ pul di pat we dɔn pwɛl na di kɔlon (wan kɔlektɔmi) fɔ mek dɛn nɔ gɛt mɔ prɔblɛm ɔ risk dɛn.

If yu gɛt kɔlektɔmi, bɔku tɛm yu go nid fɔ du ɔstomi bak. Ostomy na wan opin we dɛn mek na yu bɛlɛ fɔ mek di stɔl pas. Dis na di opin we di stɔl de pas we yu insay nɔ de wok fayn. Dipen pan di kayn kɔlektɔmi we yu gɛt, yu kin nid fɔ gɛt ostomy fɔ sɔm tɛm ɔ fɔ ɔltɛm. Ilɛksɛf na fɔ shɔt tɛm ɔ fɔ lɔng tɛm, fɔ ajɔst to di ostomy kin bi big chenj ɛn i kin at smɔl, mɔ we i gɛt imejensi. Bɔt yu go gɛt di sɔpɔt we yu nid fɔ go tru am.

Yu tink se dɛn kin mɛn pɔyzin mɛgakolon?

Yɛs, if yu go to tritmɛnt kwik, yu chans fɔ liv rili bɔku. Na lɛk 93% pan di pipul dɛm wae dɛn kin trit fɔ `(Toxic Megacolon)` kin mek dɛn wɛl ful wan. כltu, if komplikashכn dεm lεk intestinal pεrforeshכn apin, di rεt we de liv na bכt 75%. כl di komplikashכn dεm kin apin we dεn nכ trit `(Toxic Megacolon)` fכ lכng tεm. So, e fayn fɔ ɔndastand aw yu sik siriɔs ɛn du tin kwik kwik wan.

Pɔyzin mɛgakolon na mɛdikal imejensi we kin kam wantɛm wantɛm ɛn we yu nɔ bin de ɛkspɛkt. Yu de pan big risk if dɛn nɔ tu te yet we dɛn dɔn no se yu gɛt inflammatory bowel disease (IBD) we dɛn nɔ kin kɔntrol fayn. Bɔt i kin apin bak we pɔsin gɛt siriɔs infɛkshɔn ɔ ɔda bad bad kɔlayt. Yu fɔ no bɔt ɛni chenj ɔr wɔs pan yu ɔspitul sayn dɛm.

If yu gɛt siriɔs kɔlayt ɛn yu bigin fɔ fil bad ɔ yu gɛt pɔyzin, go to dɔktɔ wantɛm wantɛm. Fɔ trit yu kwik na di bɛst we fɔ mek yu nɔ gɛt prɔblɛm dɛn we go mek yu layf de pan denja. I kin ɛp yu bak fɔ avɔyd ɔpreshɔn. Ivin if yu fɔ du imejensi colectomy ɛn ostomy, mɛmba se yu go gɛt ɔl di ɛp we yu nid fɔ ajɔst to di chenj dɛn.

Di tin we impɔtant pas ɔl (Take-Home Message) .

Toxic Megacolon na wan rili siriɔs, imejensi kɔndishɔn we kin apin na di big intestinal. I kin kam wit siriɔs kɔlayt (inflammation/injury of the colon). If yu gɛt sɔm sayn dɛn lɛk fɔ blo, yu bɛlɛ de at bad bad wan, yu gɛt blɔd dayarɛa, fiva, ɛn yu at de bit kwik kwik wan, nɔ ignore dɛn. Dis na mɛdikal imejensi. If yu gɛt ɔspitul tritmɛnt kwik, yu kin mek yu wɛl ful wan. So, if yu gɛt dɛn sik ya, go to dɔktɔ wantɛm wantɛm. Di mɔ yu wet, na di mɔ yu go gɛt prɔblɛm dɛn ɛn na di mɔ yu go day. Tek kia ɔf yu wɛlbɔdi.

` Toxic Megacolon, Colitis, Inflameshɔn na di kɔlon, Bɛlɛ pen, Dayarɛa, Ɔpreshɔn, Imejɛnsi