Yu no bɔt dis fɛns we de ɔlsay? - Lɛ wi tɔk bɔt Aspergillus fumigatus

As yu no, bɔku bɔku smɔl smɔl tin dɛn de na di say we wi de liv, dat na di briz, di grɔn, ɛn di plant dɛn. Sɔm pan dɛn tin ya na fɛns. Di Aspergillus fumigatus we wi go tɔk bɔt tide na wan pan dɛn kayn fungus ya we rili kɔmɔn na wi envayrɔmɛnt. Fɔ pɔsin we gɛt wɛlbɔdi ɛn we gɛt gud imyun sistɛm, dis fɛns nɔ kin du ɛni bad tin ilɛksɛf i go insay di bɔdi. Di difens sistɛm na wi bɔdi de kɔntrol am. Bɔt if pɔsin in imyun sistɛm wik bikɔs ɔf wan patikyula sik ɔ mɛrɛsin, dis fɛns kin mek i gɛt denja infɛkshɔn.

Wetin mek dis fungus denja fɔ sɔm pipul dɛn nɔmɔ?

Fɔ tɔk am simpul wan, dis fɛns na pɔsin we de tek chans. Dat min se, i nɔ go ebul fɔ du ɛnitin as lɔng as wi bɔdi in difɛns, ɔ di imyun sistɛm, strɔng. Bɔt jɔs afta dɛn difens dɛn ya wik, i kin es in ed ɔp ɛn bigin fɔ mek prɔblɛm.

Wetin na di situeshɔn dɛm wae di imyuniti kin wik?

• We di bɔdi wik bikɔs ɔf rizin dɛn lɛk siriɔs sik, we i nɔ de it fayn, ɔ we i dɔn ol.
• Immunosuppression bikɔs ɔf sɔm sik dɛn (fɔ ɛgzampul, AIDS) ɔ mɛrɛsin (fɔ ɛgzampul, kansa tritmɛnt, mɛrɛsin we dɛn kin gi afta dɛn dɔn transplant ɔgan).
• Implant di prɔstɛtik divays dɛn.
• Kכndishכn dεm lεk nyutropenia fכ lכng tεm.

If pɔsin we de na dis kayn sik gɛt dis fεnshכn, i kin ivin put in layf pan denja.

Aw dis fεn infεkshכn (Aspergillosis) de divεlכp εn in simptom dεm

di spכr dεm fכ dis fכn de go insay di bכdi wit di briz we wi de blo. Dɛn kin rich fɔs na di nos, di trot, di sayn dɛn we de na di sayn, ɛn di lɔng dɛn. Di imyun sɛl dɛm fɔ pɔsin we gɛt wɛlbɔdi nɔ de alaw dɛn fɔ gro. Bɔt insay pɔsin in bɔdi we nɔ gɛt bɛtɛ imyun sistɛm, dɛn spɔt ya kin gro, gro to fɛns hayfa, ɛn bigin fɔ kam insay di tisu dɛn, mek blɔd klɔt (thrombosis), ɛn mek i gɛt alɛji.

Bɔku tin dɛn de we dis infɛkshɔn kin kam wit. Di sayn dɛm de dipen pan di ɔgan we gɛt di sik ɛn yu imyun sistɛm.

Alɛji fɔ fɛns

Sɔntɛnde dis fɛns kin mek yu gɛt alɛji pas fɔ mek yu gɛt invasiv infɛkshɔn. Bɔku tɛm, dɛn tin ya nɔ kin mek pɔsin in layf de pan denja, bɔt dɛn kin mek pɔsin sik.

Di wan we kin bɔku pan dɛn na Alɛji Brɔnkopulmonari Aspɛrgilɔsis (ABPA) . Dis kin bɔrku pan pipul dɛm wae gɛt lכng sik we bin dɔn de bifo. Fɔ ɛgzampul, pipul dɛm wae gɛt sik lɛk asma, sistik fibrosis, ɔr bronchiectasis kin gɛt bɔrku risk.

dis na we di bכdi de riak pasmak to fכn spכr dεm we de kam insay tru brith. Dis kin mek yu gɛt sayn dɛn we tan lɛk asma, lɛk we yu de swɛt, kɔf, ɛn i nɔ kin izi fɔ blo.

Yu dɔktɔ go ɔda sɔm tɛst fɔ no if yu gɛt ABPA.

• Tεst fכ chεk fכ εlevεt lεvεl fכ wan kayn wayt blכd sεl we dεn kכl eosinophils insay di bכdi.
• Skin test fɔ Aspergillus antijen.
• Test di blɔd lɛvɛl fɔ Aspergillus antibodies ɛn IgE.
• X-ray na di chɛst.

Wetin na di tritmɛnt dɛn we yu kin gɛt?

Fɔ trit dis fεn infεkshɔn kin kɔmplikt smɔl. I rili nid fɔ gɛt dɔktɔ in advays. Nɔ ɛva tray fɔ trit am fɔ yusɛf.

• Antifungal drugs: Dipen pan di kayn infekshɔn ɛn aw i siriɔs, yu dɔktɔ kin gi yu mɛrɛsin lɛk amphotericin B ɛn voriconazole. Dɛn tritmɛnt ya kin nid fɔ tek sɔm wiks ɔr fɔ lɔng tɛm.
• כpεrayshכn: big fכn bכl dεm (aspergillomas) we de fכm na di lכng dεm nכ de trit wit mεdikeshכn nכmכ. Dɛn nid fɔ du ɔpreshɔn fɔ pul dɛn. Dɔn bak, if yu gɛt fɛns sayɛns, i kin nid fɔ ɔpreshɔn fɔ klin di sayn dɛn ɛn alaw di wata fɔ kɔmɔt.
• Alɛji tritmɛnt: If yu gɛt alɛji kɔndishɔn lɛk ABPA, di men tritmɛnt na fɔ gi stɛroyd (e.g. prednisolone). Dɛn tin ya kin kɔntrol di we aw di bɔdi de du tin pasmak. Sɔntɛnde dɛn kin gi antifungal mɛrɛsin bak fɔ ridyus di doz fɔ stɛroyd ɛn fɔ mek di sayd ɛfɛkt dɛn nɔ bɔku.

Di wan dɛn we nɔ de tek drɔgs

כnכfכs, sכmtεm dis fכns kin bi rεsistant to di antifכngal dεm we wi de yuz, spεshal wan di azol dεm. Dis kin mek di tritmɛnt nɔ izi fɔ am. So, i rili impɔtant fɔ tek di mɛrɛsin jɔs lɛk aw yu dɔktɔ tɛl yu fɔ tek am, ɛn fɔ di rayt tɛm.