Tink bɔt am, wi ɔl kin tek am se ɛvri sɛl na yu bɔdi gɛt yu yon DNA, nɔto so? Na di bɛsis tin we wi no bɔt jenɛtiks. Bɔt, na smɔl tɛm nɔmɔ, pɔsin in bɔdi kin gɛt sɛl dɛn we gɛt sɛkɔn kayn DNA we nɔto in yon, ɛn we difrɛn atɔl. I tan lɛk se i strenj smɔl, nɔto so? Insay mɛrɛsin, wi kin kɔl dis wɔndaful kɔndishɔn ‘Chimerism’. Nɔ wɔri, i nɔto sik. Lɛ wi si wetin i rili bi.
Wetin na ‘Chimerism’?
Fɔ tɔk am simpul wan, chimerism na we tu sɛt sɛl dɛn de insay di sem pɔsin in bɔdi we kɔmɔt frɔm tu pipul dɛn we difrɛn frɔm dɛn jɛnɛtiks. Dis min se sɔm sɛl dɛn na yu bɔdi kin gɛt wan kayn DNA, ɛn ɔda sɛl dɛn kin gɛt difrɛn kayn DNA atɔl.
Wan pan di men we dɛn we dis kin apin na we dɛn bɔn twin pikin dɛn. Imajin se mama de kɛr twin pikin dɛn na in bɛlɛ. insay di fכs wik dεm we di bεlε de, wan pan di εmbrayo dεm kin nכ de divεlכp εn i kin dכn fכ sכm rizin. Dɛn kɔl dis Vanishing Twin Syndrome. we dis apin, di sεl dεm frכm di εmbriyo we nכ de, di כda εmbrayo we de divεlכp hεlty de abzכp. so, di pikin go gεt in yon sεl dεm εn di sεl dεm we de kכmכt frכm di bכda in bכda in bכdi we nכ de insay in layf.
di kayn sεl dεm we de kam togεda dis kayn we de difrεn frכm dεn wan dεm. Bɔku tɛm, dɛn kin si dis difrɛns na di blɔd. Dɛn kɔl am ‘blɔd chimerism’. dis na biכs di bכdi sεl dεm we de fכm na di bon mכro strכng εn i kin izi fכ pas tru di plasεnta. akɔdin to risach, lɛk 8% pan di nɔmal twin pikin dɛn kin gɛt dis sik. pan triplet dεm, dis prכbabiliti de inkrεs to 21%.
Wetin na di tin dɛn we kin mek pɔsin gɛt chimerism?
As wi bin dɔn tɔk, sɔm pipul dɛn kin bɔn wit dis sik. Bɔt sɔmbɔdi kin gɛt chimerism insay in layf. Tu men rizin dɛn de fɔ dis. Mek wi brok dem daun laik dis.
| Mek | Diskripshɔn bɔt aw i kin apin |
|---|---|
| Chimerism we dɛn bɔn wit | Dis na di ‘Vanishing Twin Syndrome’ we wi bin dɔn tɔk bɔt bifo tɛm. wan εmbrayo de lכs insay di bכdi εn in sεl dεm de tek di כda εmbrayo, we de mek tu kayn sεl dεm de na di bכdi כl di layf. |
| Chimerism we dɛn dɔn gɛt | Dɛn kin du dis as mɛrɛsin we go sev pɔsin in layf. Fɔ ɛgzampul, tink bɔt aw fɔ transplant wan ɔgan . We pɔsin gɛt kidni frɔm ɔda pɔsin we gɛt wɛlbɔdi, di nyu kidni de wok wit di pɔsin we gi am in DNA. Dɔn di pɔsin we gɛt di sik kin gɛt dɛn yon DNA ɛn di pɔsin we gi am in DNA. Na di sem tin kin apin to pɔsin we dɛn kin transplant bon mɛro . insay dis kes, dεn kin transplant di bon mכro fכ wan hεlty dona insted fכ di bon mכro we sik. Dɔn dɛn kin mek ɔl di nyu blɔd sɛl dɛn frɔm di pɔsin we gi di blɔd in DNA. Dis kin ivin chenj di kayn blɔd we pɔsin gɛt. |
Ɛni sayn de fɔ dis?
Di gud nyus na dat, bɔrku pipul dɛm wae gɛt chimerism nɔr kin gɛt ɛni sayn. Bɔrku pipul kin go dɛn ɔl dɛn layf ɛn nɔr kin no se dɛn gɛt dis sik. Bikɔs no patikyula tɛst nɔr de fɔ am, i nɔr kin izi fɔ gɛt diagnosis.
Bɔt sɔntɛnde dis kin mek wi gɛt prɔblɛm dɛn we wi nɔ go ebul fɔ imajin, mɔ we dɛn de tɛst DNA.
Imajin se, papa de du DNA tɛst fɔ no if pikin na papa. Bɔt di tin we kin apin kin kɔmɔt na do se nɔto in na di pikin in papa. I shɔ se na in yon pikin. wetin kin apin ya na dat if di papa de sɔfa wit chimerism, di DNA nɔ de insay in blɔd ɔ saliva, bɔt na in riprodaktiv sɛl dɛn (sperm). Na di DNA fɔ di brɔda we bin lɔs insay di bɛlɛ. Dɔn bay jɛnɛtiks di pikin gɛt fambul to am jɔs lɛk se na wan pan in brɔda dɛn pikin, dat na, in brɔda in pikin ɔ in sista in pikin.
Di sem tin kin apin to mama, insɛf. fכ dat, bכku tεm, dεn kin no se chimerism de bi as a rizulεt fכ wan random mismatch we dεn de du DNA tεst lεk dis.
Dis tin we kin apin kin mek wi gɛt siriɔs prɔblɛm?
Chimerism nɔto sik ɔr denja, bɔt i kin kam wit sɔm prɔblɛm dɛn if yu nɔ no bɔt am.
- Ligal Isyu: As wi bin dɔn tɔk, if dɛn nɔ kɔrɛkt di tɛst fɔ no if dɛn na papa, dat kin mek dɛn gɛt big big ligal prɔblɛm dɛn we gɛt fɔ du wit aw fɔ kia fɔ pikin. Dɛn dɔn ripɔt bɔku tin dɛn lɛk dis ɔlsay na di wɔl.
- Prɔblɛm dɛn we pɔsin kin gɛt na in maynd:Sɔm pipul kin gɛt smɔl saykilɔjik shɔk ɛn aydentiti prɔblɛm we dɛn kam fɔ no se dɛn gɛt pat pan ɔda pɔsin in bɔdi.
- di mεdikal minin: I kin imכtant fכ no dis kכndyushכn we di tisu dεm de mach bifo dεn transplant כgan.
Bɔt mama dɛn nɔ nid fɔ wɔri bɔt ‘vanishing twin syndrome’. If i apin insay di fɔs tri mɔnt we di bɛlɛ de, i nɔ go ambɔg di mama ɔ di pikin we gɛt wɛlbɔdi. Di mama nɔ kin notis ɛni ɔda sayn pas fɔ blɔd smɔl.
Mɛsej we dɛn kin kɛr go na os
- Chimerism na di prεsεns fכ tu tכp DNA insay wan כganism. dis kin apin bכku tεm tru di absכpshכn fכ sεl dεm frכm twin insay di bכdi כ tru wan כgan/bon mכro transplant.
- Dis nɔto tin we de mek pɔsin denja. Bɔrku pipul dɛm wae gɛt chimerism nɔr kin gɛt ɛni sayn.
- Di men prɔblɛm kin apin wit DNA tɛst, mɔ pan tin dɛn lɛk paternity test, usay di rizɔlt kin nɔ kin gri.
- If yu ɛva gɛt prɔblɛm we yu nɔ ɛksplen bɔt di rizɔlt fɔ DNA tɛst, tɔk to yu dɔktɔ bɔt di pɔsibul fɔ mek yu gɛt chimerism.
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