Wali olabye omuntu ng’agolodde emikono gye mu maaso ge, ate amangu ago emikono gye ne gigwa wansi ate n’adda waggulu nate nga talina ky’afuga? Kiringa ekiwujjo ekikuba ebiwaawaatiro byakyo. Kino osanga ggwe kennyini okifunyeemu. Kino si kukankana kwa bulijjo. Mu busawo, tugiyita Asterixis. Mu butuufu si bulwadde, wabula kabonero ka mbeera ya bujjanjabi. Kale lwaki kino kibaawo? Kino kintu kya kutya? Ka twogere ku nsonga eno mu ngeri ennyangu era mu ngeri entegeerekeka.
Ddala Asterxis kye ki?
Mu ngeri ennyangu, asterixis bw’oba okozesa ekinywa (okugeza, ng’ogolola omukono mu maaso), ekinywa ekyo kiwummulamu okumala akaseera. Kino kiva ku kutaataaganyizibwa okumpi ennyo mu bubonero obuva mu bwongo.
Kuba akafaananyi ng’osika ku bbugwe. Kiki ekibaawo singa ebinywa by’omukono gwo biwummudde mu bwangu okumala ekiseera ekitakka wansi wa sikonda emu? Omukono gwo gugenda mu maaso n’oluvannyuma ne gudda mu kifo we gwali? Asterixis kintu ng’ekyo. Erinnya eddala lye tuwa kino mu ddagala lye `(Negative myoclonus)`. Wano, ``Negative'' tekozesebwa mu makulu ga ``kibi''. Mu budde obwabulijjo, ekinywa bwe kikankana, tugamba nti ``(Positive myoclonus)``, ekitegeeza ``okweyongera kw'emirimu.'' Ekibaawo wano kiri nti ekinywa ekyali kyakola edda kiyimirira okumala akaseera, kale kiyitibwa ``(Negative myoclonus)``, ekitegeeza ``okukendeera kw'emirimu.''
Embeera eno eyinza okuva ku kizibu ekikwata butereevu ku bwongo, oba eyinza okubaawo ng’embeera ey’okubiri ekosa obwongo olw’ekizibu ekiri awalala mu mubiri (e.g., ekibumba, ensigo).
Omuntu alina obulwadde bwa asterixis otegeera otya?
Obulwadde bwa Asterixis butera okukwata enjuyi zombi ez’omubiri. Kyokka oluusi kiyinza okukosa oludda lumu lwokka oba oludda olusukka mu lumu. Ng’oggyeeko obubonero buno, obubonero ng’otulo, okutabulwa, n’okubulwa ekifo n’obudde nabyo bulabibwa.
Waliwo engeri bbiri enkulu omusawo gy’agenda okukebera kino:
1. Enkola y’okuggyamu engalo: Omusawo ajja kukugamba okukwata emikono gyo butereevu mu maaso go, engalo nga zitunudde wala okuva gy’oli, ng’olinga azibye bbugwe atalabika. Engalo zo zirina okusaasaanyizibwa nga zigazi. Singa okwata ekifo kino okumala sekondi nga 30 n’emikono gyo ‘gikuba’ wansi mu bwangu n’oluvannyuma n’odda waggulu nga tolina buyinza, kiyinza okuba nga kya asterixis.
2. Enkola y’okukwata: Mu nkola eno, osabibwa okunyweza emikono gy’omusawo n’egyammwe. Bw’oba okola bw’atyo, omusawo ajja kuwulira singa enkwata yo enafuwa mpolampola era enafuwa.
Ekikulu nti obubonero bwa Asterixis buyinza obutalabika mangu mu kukebera kuno. N’olwekyo, omusawo ayinza okukusaba okusigala mu mbeera eyo waakiri okumala eddakiika emu.
Lwaki Asterxis eno ebaawo? Biki ebikulu ebivaako?
Waliwo ensonga eziwerako lwaki asterixis esobola okubaawo. Ensonga enkulu eri nti ebitundu ebikulu mu mubiri gwaffe tebikola bulungi. Ka tulabe ensonga zino kye ziruwa.
| Ekika ky’ensonga | Ennyinyonnyola ennyangu |
|---|---|
| Obuzibu mu kibumba n’ensigo | Ekibumba n’ensigo bisengejja obutwa mu musaayi gwaffe. Ebitundu bino bwe biba tebikola bulungi, obutwa obwo bukuŋŋaanyizibwa mu musaayi. Okuva obutwa buno bwe bukwata ennyo ku bwongo, busobola okwonoona obutoffaali bw’obwongo ne bukosa enkola y’obwongo. Embeera ng’ekibumba okulemererwa, ekibumba okulemererwa, n’obulwadde bwa cirrhosis ziyinza okuvaako kino . |
| Okwonooneka kw’obwongo | Obuvune oba endwadde ku bwongo busobola okuleeta okwonooneka (ebiwundu) mu bitundu ebimu eby’obwongo. Singa ebiwundu bino bikosa ebitundu ebifuga ebinywa, asterixis esobola okubaawo. Mu mbeera ng’ezo, obubonero buno butera okulabibwa ku ludda olumu lwokka olw’omubiri. |
| Embeera endala ez’obujjanjabi | Embeera eno era esobola okuva ku nkyukakyuka mu kemiko mu musaayi. Eby’okulabirako: ssukaali omutono mu musaayi (hypoglycemia), potassium omutono (hypokalemia), magnesium omutono (hypomagnesemia), omutima okulemererwa, n’okulemererwa okussa. Ekirala, obulwadde obuva mu buzaale obuyitibwa Wilson disease, obuleetera ekikomo okukuŋŋaanyizibwa mu mubiri, bwe buvaako. |
Obulwadde bwa Asterixis obuva ku ddagala
Oluusi, asterixis nayo esobola okubaawo okumala akaseera ng’ekizibu ky’eddagala erimu lye tumira. Obulabe buno buba bungi naddala mu bantu abalina obuzibu mu kibumba oba ekibumba.
Bino bye bimu ku byokulabirako:
- Eddagala eriweweeza ku bulwadde bw’okusannyalala: naddala phenytoin. Obulwadde bwa Asterixis obuva ku kino era buyitibwa "phenytoin flap". Era kiyinza okuva ku ddagala nga gabapentin, valproate, ne carbamazepine.
- Ebirungo ebiyitibwa barbiturates
- Eddagala lya Benzodiazepines
- Eddagala erimu eritta obuwuka
- Lithium (eddagala erikozesebwa okutebenkeza ebirowoozo) .
- Metoclopramide (eddagala eriziyiza okusesema) .
Kino kikwatibwa kitya?
Tewali ddagala butereevu ku kabonero ka asterixis. Abasawo bagezaako okuzuula ekivaako ne bakijjanjaba okusinziira ku mbeera.
Okugeza nga:
- Singa ekivaako kizibu kya kibumba, kijja kujjanjabibwa.
- Singa ekivaako kizibu kya kibumba, kijja kujjanjabibwa.
- Singa ekivaako kiva ku ddagala erikozesebwa, omusawo ajja kusalawo oba akyusa eddagala oba okukendeeza ku ddoozi.
N’olwekyo bw’oba olina obulwadde bwa asterixis, ekisinga obukulu kwe kuzuula ekituufu ekivaako n’otandika okubujjanjaba. Kino si kintu ky’osobola okujjanjaba awaka ku bubwo.
Biki ebiyinza okuvaamu singa tebijjanjabwa?
Obulabe obusinga obuli mu kubuusa amaaso obulwadde bwa asterixis kwe kuba nti buyinza okuvaako embeera z’obujjanjabi ez’amaanyi eziyinza okutta omuntu. Singa tebujjanjabwa, kiyinza okukosa obwongo obw’olubeerera, omuli okubulwa endowooza, okutambula, n’okukozesa ebitundu by’omubiri.
Singa obulwadde bwa asterixis bukosa amagulu oba omugongo, buyinza okuvaako okugwa okw’amangu ekiyinza okuvaako omuntu okufuna obuvune obw’amaanyi.
Ddi lw’osaanidde okunoonya amagezi mu bwangu omusawo?
Bw’oba olina n’okuteebereza okutono nti olina obubonero bw’obulwadde bwa Asterxis, mazima ddala wandibadde olaba omusawo.
Wabula bw’oba olina obubonero buno wammanga, kitwale ng’embeera ey’amangu ey’obujjanjabi :
- Singa wabaawo okutabulwa mu birowoozo wamu n’obubonero bw’obulwadde bwa asterixis.
- Bw’oba olina okutaataaganyizibwa (okufiirwa ekifo, obudde, oba endagamuntu ).
- Singa enkyukakyuka endala mu birowoozo ziragibwa.
Obubonero buno bulaga nti enkola y’obwongo ekosebwa nnyo. Nolwekyo, mu mbeera ng’ezo , kikulu nnyo okugenda mu ddwaaliro mu kitongole ekikola ku bujjanjabi obw’amangu (ETU) mu bwangu.
Obubaka Obutwala Awaka
- Obulwadde bwa Asterixis si bulwadde. Kabonero akalaga embeera ey’amaanyi eyinza okukosa ekibumba, ensigo, omutima oba obwongo.
- Bw’oba ggwe oba omuntu gw’omanyi alina akabonero kano ak’okuwuubaala emikono, tokabuusa maaso. Laba omusawo amangu ddala nga bwe kisoboka.
- Singa akabonero kano kawerekerwako okutabulwa, otulo oba okulemererwa okutegeera, kiba kya mangu. Genda mu kitongole ky’abalwadde ab’amangu (ETU) mu bwangu.
- Embeera eno erina okuzuulibwa n’okujjanjabibwa omusawo yekka. Weewale okugezaako okwejjanjaba oba okwezuula.
👩🏽 ⚕️ Ebibuuzo ebirala (FAQs)
💬 Empeke za Macitentan (Opsumit) ddagala ddene nnyo eriweebwa ku bulwadde ki?
Lino si ddagala lya bulijjo! Lino ddagala erikola obulungi ennyo (Endothelin Receptor Antagonist) erijjanjaba ‘Pulmonary Arterial Hypertension (PAH),’ obulwadde obutta abantu ng’emisuwa egiva ku mutima okutuuka mu mawuggwe gifunda/gyekaluba, era puleesa munda mu misuwa egyo n’efuuka waggulu nnyo n’ekutuka n’omulwadde n’afa. ‘Elwawo okukulaakulana kw’obulwadde’ n’okuwangaaza obulamu, okusinga obubonero bwokka!
💬 Bw'oba ofa omusaayi ogukutte mu mawuggwe, ogaziya otya emisuwa gyo/ofuga obulwadde nga omira empeke zino (Macitentan)?
Emisuwa mu mawuggwe gilagirwa okukonziba n’okukaluba (Fibrosis) olw’eddagala ery’akabi mu mubiri gwaffe lyennyini eriyitibwa ‘Endothelin-1’! Amangu ddala ng’empeke eno eyingira mu musaayi, eziyiza emikisa 100% egy’eddagala eryo okwesiba ku bikwata mu misuwa (both ETA ne ETB receptors - Dual block). Tekikoma awo, eddagala lino era liyimiriza emisuwa okugonza nga liyingira mu butoffaali mu mawuggwe (Tissue penetration).
💬 'Black Box Warnings' abakyala/abasajja abamira eddagala lino (Opsumit) gye balina okumanya?
Obulabe obusinga obunene kwe kuba nti kino kikugirwa nnyo eri ‘Bamaama ab’embuto’! Singa ofuna olubuto ng’onywa kino, omwana mazima ddala ajja kuba mulema (Major Birth Defects) era afiire munda (bamaama balina okuba nga bagoberera pulogulaamu ya REMS). Okugatta ku ekyo, kino mazima ddala kijja kuleeta ‘Decreased sperm count / Infertility’ mu basajja! Ekirala, hemoglobin (Anemia) y’abantu abamu esobola okukka ennyo n’evaako okukendeeza ku musaayi.
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