Bw’omanya nti olina kookolo, owulira ng’otya nnyo n’okukankana. Olwo abasawo bwe boogera ku bujjanjabi, owulira eddagala eppya lingi n’ebigambo ebipya by’ototegeera. Oluusi, ebintu bino bw’otobitegeera bulungi, okutya kwo kweyongera. Avastin ddagala lya njawulo katono erikozesebwa mu kujjanjaba kookolo . Kale leero, ka twogere ku ddagala lino eriyitibwa Avastin (Bevacizumab) mu ngeri ennyangu gy’osobola okutegeera.
Okusooka, ka tulabe eddagala lino eriziyiza Angiogenesis ki.
Okusobola okutegeera kino, ka tukozese ekyokulabirako eky’enjawulo. Teebereza ekizimba ky’obutoffaali bwa kookolo ng’omuddo omubi ogumera mu lusuku lwaffe. Omuddo guno gwetaaga ki okukula n’okusaasaana mu lusuku lwonna? Mazima ddala kyetaaga amazzi. Mu ngeri y’emu ekizimba kya kookolo nakyo kyetaaga omusaayi okusobola okukula n’okusaasaana mu bitundu by’omubiri ebirala.
Kale kookolo ono mukuusa nnyo. Kiweereza “akabonero” eri omubiri gwaffe okufuna omusaayi gwe gwetaaga n’okukulaakulanya emisuwa emipya . Nga ekimera ekyo eky’omuddo bwe kirima enkola empya eya payipu wansi w’ettaka okuleeta amazzi. Eddagala eriyitibwa angiogenesis inhibitors liyimiriza okukula kw’emisuwa gino emipya. Kwe kugamba, ziziba “emisuwa” egigenda ku kookolo. Olwo omusaayi bwe gubula, kookolo tasobola kukula wadde okusaasaana.
Kale Avastin (Bevacizumab) ekola etya?
Avastin ddagala eriri mu kibinja kya Angiogenesis inhibitor kye twayogeddeko waggulu. Okubeera omutuufu, lino ddagala eriri mu kiraasi ey’enjawulo eriyitibwa Monoclonal antibody .
Kati oyinza okuba nga weebuuza nti antibody ya monoclonal antibody kye ki. Mu ngeri ennyangu, ye puloteyina ekoleddwa mu ngeri ey’enjawulo mu laboratory, efaananako n’obutoffaali obuziyiza endwadde omubiri gwaffe bwe gukola mu butonde okulwanyisa endwadde. Ekintu eky’enjawulo ku kino kiri nti tekikosa butoffaali bwonna mu mubiri ng’eddagala erya bulijjo erya kemotherapy, wabula kikwata butoffaali bwa kookolo bwokka mu bujjanjabi obugendereddwamu .
Avastin etunuulidde VEGF (Ensonga y’okukula kw’emisuwa) .Molekyulu. Twagamba emabegako nti kookolo asindika “akabonero” okukola emisuwa emipya, era akabonero ako ye VEGF. Avastin ky’ekola yeekwata ku molekyu eno eya VEGF n’agiremesa okukola. Kiringa “okuggyako” siginiini. VEGF bw’elekera awo okukola, emisuwa emipya tegikola, era kookolo abulwa ebiriisa bye.
Nze nneetaaga eddagala lya Chemotherapy singa nmira Avastin?
Yee, kino kizibu eri abantu bangi. Wadde nga Avastin ddagala erigendereddwamu, tekola yokka . Kiba ng’omuzannyi awagira. Omuzannyi omukulu mu mboozi eno, nga ye chemotherapy, akyetaagisa.
Chemotherapy kika kya ddagala lya maanyi eritta obutoffaali obweyawukana amangu (nga obutoffaali bwa kookolo). Avastin akola ng’ayamba ku ddagala ly’eddagala.
Naye ekisinga obulungi, Avastin bw’egattibwa n’eddagala eriweweeza ku bulwadde, ebiva mu kujjanjaba eddagala biba bya buwanguzi n’okusingawo. Kwe kugamba, eddagala lino ebbiri bwe ligatta, okulwanyisa kookolo kweyongera amaanyi. Nga eddagala lya Chemo likendeeza ku musaayi ogugenda mu kizimba, litta obutoffaali bwa kookolo.
Bika ki ebya kookolo ebijjanjabwa n’eddagala lya Avastin?
Avastin akkiriziddwa ku bika bya kookolo bingi . Kyokka tebuweebwa ku kookolo yenna. Omusawo wo ajja kusalawo oba eddagala lino likusaanira okusinziira ku kika kya kookolo gw’olina, omutendera gwe, n’obulamu bwo okutwalira awamu.
Omulongooti guno gulaga ebimu ku bika bya kookolo ebisinga okukozesebwa Avastin.
| Ekika kya kookolo | Amawulire amakulu |
|---|---|
| Kookolo w’olubuto olunene oba mu nseke | Kisinga kukozesebwa mu mbeera nga kookolo asaasaanidde mu bitundu by’omubiri ebirala (metastatic). Kitera okuweebwa n’eddagala eriweweeza ku bulwadde nga 5-fluorouracil (5-FU) oba capecitabine (Xeloda) . |
| Kookolo w’amawuggwe | Ekozesebwa ku bika ebimu ebya kookolo w’amawuggwe agenda mu maaso. |
| Kookolo w’ekibumba | Ekozesebwa ku kookolo w’obutoffaali bw’ekibumba (metastatic renal cell carcinoma). |
| Kookolo w’enkwaso | Akozesebwa ng’eddagala erijjanjaba abamu ku kookolo w’enkwaso. |
| Kookolo w’omumwa gwa nnabaana | Ekozesebwa ku kookolo w’omumwa gwa nnabaana azzeemu oba asaasaana. |
| Obulwadde bwa glioblastoma | Kino kika kya kookolo w’obwongo, era obujjanjabi buno busobola okuweebwa singa addamu okukwatibwa. |
Avastin taweebwa ku kookolo w’amabeere?
Wadde nga Avastin emabegako yali ekozesebwa okujjanjaba kookolo w’amabeere, okunoonyereza okwakolebwa oluvannyuma kwakakasa nti obulabe bw’ebizibu ebivaamu bwasinga emigaso gy’eddagala lino. N’olwekyo ebitongole nga FDA mu Amerika tebikyakkiriza kukozesa ddagala lya Avastin ku kookolo w’amabeere.
Avastin asobola okuwonya ddala kookolo w’olubuto olunene?
Nedda Avastin si ddagala lya “bulogo” eriwonya ddala kookolo . Kyokka, okugezesebwa mu malwaliro kulaga nti eddagala lino liyinza okwongera ennyo ku bulamu bw’abalwadde . Okugeza, okunoonyereza okumu kuzudde nti abalwadde abaweebwa Avastin n’eddagala lya Chemotherapy baawangaala emyezi nga 5 okusinga abo abaaweebwa eddagala lyokka. Tumanyi omulundi guno bwe guli ogw’omuwendo eri omuntu alwanyisa kookolo.
Biki ebiva mu Avastin?
Okufaananako n’eddagala lyonna ery’amaanyi, Avastin asobola okuba n’ebizibu ebivaamu. Kyokka si buli muntu agimira nti ajja kufuna ebizibu bino . Kyokka kino kikulu nnyo okukimanya. Kino kijja kukuyamba okumanya obubonero bwonna n’okutegeeza omusawo mu bwangu.
Wansi waliwo ebimu ku bizibu eby’amaanyi era ebitera okubaawo ebiyinza okubaawo.
| Ebizibu ebiva mu Avastin | |
|---|---|
| Side effect | By’olina okumanya ku nsonga eno |
| Ebizibu eby’amaanyi ebirina okuloopebwa eri omusawo mu bwangu | |
| Okukutuka mu lubuto n’ekyenda | Eno mbeera ya maanyi nnyo. Obubonero buyinza okuli okulumwa ennyo mu lubuto, omusujja n’okuziyira. Kiyinza okwetaagisa okulongoosebwa. |
| Okuvaamu omusaayi munda | Kino kiyinza okuvaako embeera eziyinza okutta omuntu nga okusannyalala. |
| Okulwawo okuwona ebiwundu | Omusawo afaayo nnyo naddala ku kugaba eddagala lino nga tannalongoosebwa oba oluvannyuma lw’okulongoosebwa. |
| Omutima Okulemererwa | Obulabe buba bungi naddala ng’omira n’eddagala eddala erya Chemo erikosa omutima. |
| Okwonooneka kw’ekibumba | Obubonero ng’okweyongera kwa puloteyina mu musulo buyinza okubaawo. |
| Ebizibu ebirala ebitera okuvaamu (tegeeza omusawo) . | |
| Puleesa ya Musaayi | Kikulu okulondoola puleesa enfunda eziwera ng’ojjanjabibwa. |
| Obukoowu | Kino nakyo kitera okuva mu bujjanjabi bw’eddagala. |
| Omusaayi guzimba mu misuwa | Weegendereze obubonero ng’okuzimba amagulu n’okulumwa. |
| Ekiddukano, okulumwa omutwe, obutayagala mmere, amabwa mu kamwa | Bino bitera okuba ebizibu ebiyinza okuddukanyizibwa. |
| Omusaayi mu musulo | Kino olina okukitegeeza omusawo mu bwangu. |
Ekisinga obukulu kiri nti, bw'oba olina obubonero buno bwonna, tomala galowooza nti, "Kino si kintu." Tegeeza omusawo wo oba ekitongole ekikwatibwako mu ddwaaliro gy’ojjanjabirwa mu bwangu. Gy’okoma okugitegeeza amangu, gy’okoma okukwanguyira okuddukanya embeera eyo.
Obubaka Obutwala Awaka
- Avastin (Bevacizumab) si ddagala lya kinnansi erya ddagala. Buno bujjanjabi obugendereddwamu obukomya okutondebwa kw’emisuwa egigabira omusaayi mu butoffaali bwa kookolo.
- Eddagala lino teritera kukozesebwa lyokka. Kiweebwa wamu n’eddagala eriweweeza ku bulwadde okwongera ku bulung’amu bwayo.
- Kino kikozesebwa ku bika bya kookolo ebitongole byokka, gamba ng’ekyenda ekinene, amawuggwe, ekibumba n’enkwaso.
- Olw’okuba ebizibu eby’amaanyi biyinza okuvaamu, kikulu nnyo okutegeeza amangu omusawo wo ku bubonero bwonna obutali bwa bulijjo ng’ojjanjabibwa.
- Bw’oba ggwe oba omuntu wo bawandiikiddwa Avastin ng’eddagala lya kookolo, kakasa nti oteesa n’omusawo wo ebibuuzo byonna oba ebikweraliikiriza by’olina . Bajja kusobola okukuwa amawulire agasinga obutuufu.
Avastin, Bevacizumab, kookolo, obujjanjabi bwa kookolo, eddagala, eddagala eriziyiza okuzaala emisuwa, eddagala lya kookolo, ebizibu ebivaamu, pilaka prathikara, anathuru abada, obujjanjabi bwa kookolo sinhala
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