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Okusooka, ka tulabe, lwaki omusaayi tegukoma mu bulwadde bwa hemophilia?
Mu ngeri ennyangu, waliwo obutoffaali obw’enjawulo obuyamba omusaayi gwaffe okuzimba. Bino tubiyita " ensonga z'okuzimba omusaayi ." Nga omusenyu bwe gwetaagibwa okukwata amatoffaali awamu ng’ozimba bbugwe, ebintu bino ebizimba omusaayi byetaagisa nnyo okukomya okuvaamu omusaayi. Omuntu alina obulwadde bwa hemophilia abulwa ekimu ku bintu bino ebizimba omusaayi.- Abantu abalina obulwadde bwa hemophilia A tebalina kintu ekiyitibwa Factor VIII.
- Abantu abalina obulwadde bwa hemophilia B tebalina kintu ekiyitibwa Factor IX.
Kale eddagala lino eppya eriyitibwa Qfitlia (fitusiran) liri ki?
Lino ddagala erikola mu ngeri eyeewuunyisa ennyo. Twayogedde emabegako ku ky’okuba nti omusaayi gwetaaga ekintu ekiyitibwa thrombin okusobola okuzimba. Mu mibiri gyaffe, waliwo puloteyina endala efuga okukola kwa thrombin eno, kwe kugamba, eyimiriza okukola thrombin endala. Kiyitibwa antithrombin .Kilowoozeeko bw’otyo. Olina ekirungo ekizimba omusaayi (thrombin) mu mubiri gwo ekiyamba omusaayi gwo okuzimba. Naye waliwo ensonga endala (antithrombin) egifuga n’okugiremesa okukola. Mu bulwadde bwa hemophilia, okukola ensonga eyamba (thrombin) mu kusooka kuba kutono. Kale ensonga eremesa (antithrombin) bw’ekola mu ngeri eya bulijjo, okuzimba omusaayi kweyongera okukendeera. Qfitlia ky’ekola kwe kukendeeza ku bungi bw’ekirungo kya antithrombin ekigiziyiza. Olwo, obungi bwa thrombin omubiri gwo gwe gukola mu butonde gukkirizibwa okukola obulungi awatali kulemesebwa. Kino kitegeeza nti ekozesa enkola y’omubiri gwennyini okukubiriza omusaayi okuzimba, okusinga okukuwa ensonga y’okuzimba gy’ofiiriddwa. Lino lye ddagala erisoose okukendeeza ku bulwadde bwa ‘anthrombin’ okukozesebwa mu kujjanjaba obulwadde bwa hemophilia.Ka twongere okunnyonnyola enjawulo eriwo wakati w’enkola zino ebbiri ez’obujjanjabi.
Enjawulo eno osobola bulungi okugitegeera okuva ku kipande kino wammanga.| Engeri | Obujjanjabi obw’ekinnansi (Factor Replacement) . | Obujjanjabi bwa Qfitlia (fitusiran). |
|---|---|---|
| Enkola y’emirimu | Ensonga y’okuzimba omusaayi (clotting factor) ebula mu mubiri eweebwa ebweru. | Kikendeeza ku antithrombin ekiziyiza omusaayi okuzimba, era kisobozesa omubiri okukozesa ennyo thrombin yagwo. |
| Engeri y'okugaba | Ebiseera ebisinga nga bayita mu misuwa. | Wansi w’olususu (subcutaneous). |
| Emirundi | Kiyinza okwetaagisa emirundi egiwerako mu wiiki. | Omulundi gumu mu mwezi oba buli luvannyuma lwa myezi ebiri (emirundi 6-12 omwaka). |
| Ku abo abalina ebiziyiza | Obujjanjabi bwa normal factor therapy tebukola, era obujjanjabi obulala obw’enjawulo (bypassing agents) bwetaagibwa. | Obujjanjabi buno era busobola okukozesebwa obulungi mu bantu abalina ebiziyiza (antibodies against the factors). |
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Check Availability →Eddagala lino linsaanira era ndikozesa ntya?
Bw’oba olina obulwadde bwa hemophilia A oba B era ng’olina emyaka egisukka mu 12, omusawo ayinza okulowooza oba eddagala lino likusaanira. Ekisinga obukulu kiri nti era esobola okukozesebwa mu bantu abafunye ebiziyiza (okuziyiza) obujjanjabi bwa factor obw’emabega. Kyokka nga tonnatandika bujjanjabi buno, omusawo wo ajja kukukebera omusaayi emirundi egiwerako . 1. Antithrombin level: Kino kipima obungi bwa antithrombin bw’eri mu musaayi gwo. Dozi ya Qfitlia esalibwawo okusinziira ku muwendo guno. 2. Enkola y’ekibumba: Ekibumba kyo kirondoolebwa nga tonnafuna bujjanjabi n’okukifuna. Eddagala lino liweebwa ng’empiso wansi w’olususu (wansi w’olususu). Kino kitegeeza nti tekiweebwa mu musuwa. Ggwe oba omulabirira osobola okugikuwa awaka ng’omaze okutendekebwa. Buweebwa mu lususu lw’olubuto, ekisambi oba emabega w’omukono ogwa waggulu. Olina okwewala ebifo ebirimu ebiwundu oba ebisala. Bw’oba wamira dda obujjanjabi obulala obw’obulwadde bwa hemophilia, oyinza okwetaaga okukomya oba okukyusa obujjanjabi obwo ng’omaze okutandika Qfitlia. Kino omusawo ajja kukunnyonnyola bulungi. Tolekera awo kumira ddagala lyo erikozesa kati oba okulekera awo okumira Qfitlia nga tolina magezi ga musawo. Bw’okola bw’otyo kiyinza okwongera ku bulabe bw’okuvaamu omusaayi.Era tusaanidde okumanya ebizibu ebivaamu? Tuyinza tutya okuziziyiza?
Okufaananako n’eddagala lyonna, Qfitlia esobola okuba n’ebizibu ebimu. Kikulu okuzimanya n'okukola emitendera okuzitangira.- Okuzimba omusaayi : Olw’okuba eddagala lino litumbula omusaayi okuzimba, tekitera nnyo kuzimba musaayi munda mu misuwa egitayagala. Omusawo ajja kusalawo ddoozi entuufu eri eddagala lyo eriziyiza omusaayi okukendeeza ku bulabe buno.
- Enziyiza z’ekibumba eziri waggulu: Abantu abamu bayinza okuba nga balina enziyiza z’ekibumba ezisukkiridde . Eno y'ensonga lwaki abasawo bulijjo balondoola embeera y'ekibumba nga bakebera omusaayi .
- Amayinja g’omu nnyindo n’okuzimba mu nnyindo: Singa ofuna obubonero ng’okulumwa ennyo mu lubuto, okuziyira, n’okusiiyibwa , tegeeza omusawo mu bwangu.
- Yinfekisoni: Waliwo akabi akatono ak’okukwatibwa yinfekisoni mu kifo we bakuba empiso. N’olwekyo, kikulu bulijjo okukuba empiso mu ngeri enyonjo era ng’omusawo bw’akulagidde. Enkola ennungi ey’obuyonjo, gamba ng’okunaaba engalo enfunda eziwera, nazo kikulu.
Obubaka Obutwala Awaka
- Qfitlia (fitusiran) ddagala ddene erijjanjaba obulwadde bwa hemophilia A ne B erikola mu ngeri ey’enjawulo.
- Kino kikola nga kikendeeza ku bungi bw’ekirungo kya antithrombin ekiziyiza omusaayi okuzimba, mu kifo ky’okuwa ekirungo ky’omubiri ekitono eky’okuzimba ebweru.
- Eddagala lino likuba wansi w’olususu, so si mu musuwa, era litera kuweebwa nnyo, gamba ng’omulundi gumu mu mwezi oba buli luvannyuma lwa myezi ebiri.
- Omusawo ajja kuzuula oba obujjanjabi buno bukusaanira oluvannyuma lw’okukeberebwa omusaayi emirundi egiwera.
- Okwewala ebizibu ebivaamu, kyetaagisa okwekebeza omusaayi (naddala antithrombin n’enkola y’ekibumba) buli luvannyuma lwa kiseera ng’omusawo bw’akulagidde.
- Weewale okuyimiriza obujjanjabi bwa Qfitlia nga tolina magezi ga musawo olw’ensonga yonna.
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