Olina obutoffaali obuyitibwa platelets bungi mu musaayi gwo? Ka twogere ku bulwadde bwa Essential Thrombocythemia!

Wali otunuulidde lipoota y’omusaayi n’olaba ng’omuwendo gw’obutoffaali obukola omusaayi (platelets) mungi nnyo? Oba ofunye ebintu ng’okuzimba omusaayi mu bifo eby’enjawulo mu mubiri gwo awatali nsonga, oba okuvaamu omusaayi gwokka? Oyinza okuba nga tewafaayo nnyo ku bintu bino. Wabula kikulu nnyo okumanya embeera etali ya bulijjo eyinza okuba emabega w’ebintu bino, gye tugenda okwogerako leero, eyitibwa Essential Thrombocythemia.

Obulwadde bwa Essential Thrombocythemia kye ki? Ka tukitegeere mu ngeri ennyangu.

Mu ngeri ennyangu, obulwadde bwa essential thrombocythemia mbeera ng’obusimu bwaffe obw’amagumba, ekkolero erisinga okukola omusaayi, bukola ekika ky’obutoffaali bw’omusaayi obuyitibwa platelets obusukka ku ekyo ekyetaagisa. Kati oyinza okuba nga weebuuza nti, " Puletelets zino ze ziruwa ?" Platelets kye kika ky’obutoffaali obusinga obutono mu musaayi gwaffe. Balinga abajaasi abato. Bwe wabaawo ekiwundu awalala n’okutandika okuvaamu omusaayi, obutoffaali buno bwe busooka okufubutuka eyo, ne bwegatta, ne bukola ekizimba ky’omusaayi okuyimiriza omusaayi. Teebereza, kiki ekibaawo singa wabaawo ekikyamu ku busimu bw’amagumba, ekkolero erikola platelets, era platelets zino ne zikolebwa mu ngeri esukkiridde? Wano obuzibu we butandikira. Embeera eno ebaawo olw’enkyukakyuka mu bumu ku buzaale mu mubiri gwaffe, kwe kugamba, enkyukakyuka . Kino si kintu ekizaalibwa nakyo, wabula ekintu ekikula mu bulamu. Eno y'ensonga lwaki kiyitibwa ``embeera y'obuzaale efunibwa.'' Ebiseera ebisinga, embeera eno ezuulibwa mu butanwa mu kukebera omusaayi okukolebwa olw'ensonga endala. Abantu abamu bayinza obutaba na bubonero bwonna. Ate era, si buli muntu nti ajja kwetaaga obujjanjabi amangu ago. Wadde nga tekisobola kuwona ddala, obujjanjabi obutuufu busobola okukendeeza ennyo ku bulabe bw’ebizibu eby’amaanyi.

Kino kikwata kitya ku mubiri gwange?

Kati otegedde ekibaawo ng’obusimu bw’amagumba bukola platelets nnyingi. Platelets zino ez’enjawulo teziringa platelets ezabulijjo, ezimu nnene okusinga eza bulijjo ate nga zirina enkula ya njawulo katono. Kiringa ekkolero erifulumya ekibinja ky’ebintu eby’omutindo ogwa wansi. Platelets zino ezitali za bulijjo, ez’enjawulo zireetera omusaayi okuzimba mu misuwa. Ebizimba bino eby’omusaayi biziyiza omusaayi okutambula, ng’ebidduka bwe biba ku luguudo. Ebizimba bino eby’omusaayi bisobola okutondebwa wonna mu mubiri. Naye zisinga kulabibwa mu bwongo, emikono n’amagulu.

Embeera eno naddala eri bamaama abali embuto eyongera ku bulabe bw’omusaayi okuzimba .

Ekirala ekyewuunyisa embeera eno oluusi esobola okuvaako omusaayi oguyitiridde.Oyinza okuba ng'olowooza nti, "Okuzimba omusaayi kye kibaawo, kale omusaayi gutambula gutya?" Ensonga eri nti omusaayi bwe guba guyitiridde, platelets zonna mu mubiri ziggwaawo. Olwo, tewali platelets zimala okuyimiriza ddala okuvaamu omusaayi singa wabaawo obuvune. Okulaba? Olw’ensonga eno, abantu abalina obulwadde bwa essential thrombocythemia bali mu bulabe bwa maanyi obw’okulwala embeera ez’amaanyi ng’okulwala omutima oba okusannyalala.

Ono kookolo? Kikwatagana n’obulwadde bwa leukemia?

Yee, obulwadde bwa thrombocythemia obukulu kika kya kookolo w’omusaayi. Abasawo bakiyita ekizimba ekiyitibwa myeloproliferative neoplasm. Mu ngeri ennyangu, mbeera ekika ky’obutoffaali bw’omusaayi (mu mbeera eno, platelets) mwe kikolebwa ekisusse. Kyokka si kika kyennyini kya kookolo w’omusaayi ayitibwa leukemia. Wabula mu mbeera ezitali nnyingi nnyo, embeera eno esobola okukulaakulana n’efuuka leukemia mu bantu abamu. Eno y’ensonga lwaki abasawo bulijjo bagitunuulidde.

Obulwadde bwa essential thrombocythemia ne thrombocytosis kintu kimu?

Amannya gano gombi gafaanagana mu ngeri emu, n’olwekyo gayinza okutabulwa. Naye waliwo enjawulo wakati w’ebintu bino byombi.

• Essential Thrombocythemia: Wano, omuwendo gwa platelet gweyongera olw’ekizibu mu busimu bw’amagumba bwennyini, so si ku bulwadde bulala bwonna.
• Reactive Thrombocytosis: Wano, omuwendo gwa platelet gweyongera nga reaction eri embeera endala ey’obujjanjabi (e.g., yinfekisoni, obutaba na kyuma , oluvannyuma lw’okulongoosebwa).

Ku byombi, embeera eyitibwa thrombocytosis esinga kubeerawo okusinga thrombocythemia enkulu.

Ani asinga okulwala embeera eno?

Essential thrombocythemia mbeera etali ya bulijjo nnyo. Okusinziira ku bibalo ebiri mu Amerika, kikwata abantu nga babiri ku buli 100,000. Abakyala balina emikisa gy’okubufuna emirundi ebiri okusinga abasajja. Embeera eno etera okukwata abantu abali wakati w’emyaka 60 ne 80. Wabula ebitundu nga 20% ku abo ababufuna tebannaweza myaka 40. Tekitera kubaawo nnyo abaana okubufuna. Bwe bakola bwe batyo, kirabika kisinga kusikira buzaale okuva mu bazadde baabwe.

Bubonero ki obulaga kino? Okitegeera otya?

Si buli muntu nti alina obubonero bwe bumu. Abantu abamu basobola okumala emyaka nga tebalina bubonero bwonna. Obubonero butandika okulabika ng’omuwendo gw’obutoffaali obukola omusaayi gweyongera mpolampola. Obubonero obukulu bwe buva ku kuzimba omusaayi. Bino bisobola okubaawo mu bifo ng’obwongo, emikono n’amagulu. Obubonero obuyinza okuva ku kuzimba omusaayi mulimu:

• Obulumi bw'omutwe obutawona .
• Okuziyira .
• Okwokya oba okukuba okuwulira mu ngalo n’engalo z’ebigere.
• Emikono n’ebigere ebizibye oba ebimyufu .
• Enkyukakyuka mu ngeri y’okwogera .
• Obulwadde bw'omutwe omuzito .
• Okukonziba .
• Obulumi oba obutabeera bulungi mu kifuba, emikono, omugongo, ensingo, akawanga oba mu lubuto.
• Ekikeeto .
• Obuzibu mu kussa (dyspnea).
• Obulumi mu kifuba .
• Obunafu .
• Ensigo egaziye - ekitundu ekisangibwa ku ludda olwa waggulu olwa kkono olw’olubuto.
• Okuvaamu omusaayi mu nnyindo (epistaxis).
• Okuvaamu omusaayi mu nnyindo.
• Omusaayi mu musulo.
• Omusaayi mu musulo (hematuria).
• Okunyiga ebiwundu mu ngeri ennyangu.
• Abakyala bafuna ensonga enzibu .

Kino kikwata kitya embuto?

Bulijjo wabaawo akabi k’omusaayi okutondebwa mu mubiri gw’omukyala ng’ali lubuto. Obulabe buno businga n’okubeera ku maama ow’olubuto alina obulwadde bwa thrombocythemia obukulu. Ekirala, obujjanjabi obumu ku mbeera eno tebusaanira bakyala ba lubuto oba abateekateeka okufuna embuto. N’olwekyo, bw’oba ​​olina embeera eno, kyetaagisa nnyo okuteesa ku nsonga eno n’omusawo wo nga tonnalowooza ku kuzaala mwana.

Tewerabira, embeera eno eyinza okuvaako omutima okulwala n’okusannyalala. Bw’oba ​​olina embeera eno, olina okukuba ku ssimu ya 1990 mu bwangu singa olaba obubonero bw’okulwala omutima oba okusannyalala.

Lwaki embeera eno ebaawo? Ensonga ze ziruwa?

Nga bwe twagambye emabegako, kino kiva ku nkyukakyuka (enkyukakyuka) mu buzaale. Zino si buzaale obubeerawo ng’azaalibwa, wabula buzaale obukyuka mu bulamu. Okusingira ddala, enkyukakyuka mu buzaale busatu ezikosa obutoffaali obusibuka mu busimu bwaffe obw’amagumba obukola obutoffaali bw’omusaayi ze zisinga okuvaako. Ensengekera z’obuzaale zino ze zino:

• (JAK2) gene: Ensengekera eno ekola enkoodi ya puloteyina eyitibwa ``(JAK2)``. Puloteeni eno eyamba okufuga okukola obutoffaali bw’omusaayi.
• (CALR) gene: Ensengekera eno ekola enkoodi ya puloteyina eyitibwa ``calreticulin''. Abanoonyereza balowooza nti kino kikola kinene mu kufuga okukula kw’obutoffaali, okwawukana, n’okufa.
• (MPL) Gene: Ensengekera eno era emanyiddwa nga ``oncogene'', obuzaale obukwatagana n'okuleeta kookolo.

Obuzaale buno bwe bukyuka, enkola y’okukola obusimu obuyitibwa platelets mu busimu bw’amagumba tefugibwa era ya mangu nnyo. Kiringa okukubwa accelerator! Wano omubiri we gukola obuwuka obuyitibwa platelets bungi okusinga bwe gusobola okukwata.

Abasawo kino bakizuula batya? (Okuzuula obulwadde)

Singa omusawo ateebereza nti olina embeera eno, bajja kusooka kwekebejja omubiri . Era bajja kukubuuza ku bubonero bwo n’okumanya oba waliwo omuntu yenna mu maka go abadde n’ebizibu ebifaananako bwe bityo. Oluvannyuma, bayinza okukola ebigezo ebimu, gamba nga:

• Complete Blood Count (CBC): Kino kikebera emiwendo gy’obutoffaali obw’ebika byonna mu musaayi gwo naddala omuwendo gw’obutoffaali obuyitibwa platelets.
• Peripheral Blood Smear: Kino kizingiramu okutwala omusaayi n’okutunuulira obutoffaali obukola omusaayi (platelets) mu microscope okulaba oba nga bwa bulijjo oba si bwa bulijjo mu nkula n’obunene. Platelets ezitali za bulijjo ziyinza okuba ennene ate nga zirina enkula ez’enjawulo.
• Okukebera obusigo bw’amagumba: Oluusi oyinza okutwalibwa akatundu akatono ak’obusimu bw’amagumba okukeberebwa (Bone Marrow Aspiration oba Bone Marrow Biopsy). Kino kiyinza okuyamba okwekenneenya obulungi embeera y’obusimu bw’amagumba.
• Okukebera obuzaale: Okukebera kuno kukolebwa okulaba oba waliwo enkyukakyuka mu buzaale bwe twayogeddeko, gamba nga (JAK2), (CALR), ne (MPL).

Ebinaava mu kukeberebwa kuno bijja kuyamba omusawo wo okwekenneenya akabi k’olina n’okukola enteekateeka y’obujjanjabi. Okutwaliza awamu, ebintu ebiyinza okuvaako embeera eno mulimu:

• Okubeera nga wa myaka egisukka mu 60.
• Okubeera omukazi.
• Olw’okuba yali amaze okuzimba omusaayi.
• Okubeerawo kw’enkyukakyuka mu buzaale ezoogeddwako waggulu mu mubiri.

Kino buli muntu yeetaaga eddagala? Obujjanjabi bwe buruwa?

Kino si kye kimu eri buli muntu. Ku bantu abamu, bwe baba nga tebalina bubonero bwonna, abasawo bayinza okukuwa amagezi ku nkola eyitibwa "okulinda n'obwegendereza." Kino kitegeeza okutunuulira obubonero n’obubonero obulabika. Abantu abalina obubonero oba abali mu bulabe obw’amaanyi obw’okuzimba omusaayi bajja kwetaaga obujjanjabi. Obujjanjabi okusinga bugendereddwamu okuziyiza okuzimba omusaayi ne/oba okukendeeza ku muwendo gw’obutoffaali obukola omusaayi. Waliwo ebika by’eddagala ebiwerako ebikozesebwa ku kino:

• Aspirin: Kino kiremesa ebizimba by’omusaayi okutondebwawo. Wabula abasawo beegendereza okuwa abantu abalina omusaayi omungi ennyo aspirin, kubanga asobola okwongera okuvaamu omusaayi mu bantu abalina obulwadde obuyitibwa acquired Von Willebrand syndrome.
• Hydroxyurea: Lino ddagala lya kemiko. Kikendeeza ku muwendo gw’obutoffaali obukola omusaayi (platelet). Asobola okuweebwa ne aspirin eri abantu abali mu bulabe obw’amaanyi obw’okuzimba omusaayi.
• Anagrelide: Okufaananako ne hydroxyurea, kino nakyo kiyamba okukendeeza ku bungi bw’obutoffaali obukola omusaayi n’obulabe bw’okulwala omutima n’okusannyalala.
• Ekirungo kya interferon alfa:Eno ddagala lya busimu obuziyiza endwadde. Kiyimiriza obutoffaali obutali bwa bulijjo okwawukana n’okukula.
• Busulfan: Lino era ddagala eriweweeza ku kookolo. Kiweebwa abantu abataddamu ddagala lya hydroxyurea oba abatasobola kukikozesa.
• Ruxolitinib: Eddagala lino likozesebwa ku bantu abatazzeemu ddagala eddala ate nga nabo balina obubonero ng’okusiiyibwa, okuwulira ng’ajjudde ne bwe balya akatono, n’okukoowa ennyo.

Oluusi, singa emiwendo gy’obutoffaali zo bweyongera mu bwangu, enkola eyitibwa plateletpheresis ekozesebwa. Mu kino, omusaayi gwo guyungibwa ku kyuma eky’enjawulo, ekiggyamu ezimu ku buwuka obuyitibwa platelets obusukkiridde.

Waliwo engeri y’okuziyiza kino okubaawo?

Mu butuufu, nedda. Kino kiva ku nkyukakyuka mu buzaale, era tewali kye tuyinza kukola kuziyiza nkyukakyuka ezo. Abanoonyereza n’okutuusa kati tebannaba kuzuula lwaki obuzaale buno bukyuka.

Kisoboka okubeera n’obulamu obwa bulijjo ng’olina embeera eno? Obulamu bwe buliwa?

Mazima ddala osobola! Ne bw’oba ​​olina obubonero, abasawo basobola okukujjanjaba okutangira ebizibu eby’amaanyi ng’okulwala omutima n’okusannyalala. N’olwekyo kikulu obutasattira n’ogoberera n’obwegendereza ebiragiro by’omusawo. Bwe kituuka ku bulamu bw’abantu, kigambibwa nti abantu abalina embeera eno bayinza okuba n’obulamu obutono okusinga abo abatalina. Kyokka kino kyawukana okusinziira ku muntu. Ensonga nnyingi, gamba ng’embeera gy’olimu n’emize gyo egy’obulamu, bikosa kino. N’olwekyo, engeri esinga okumanya ku nsonga eno kwe kubuuza omusawo wo.

Nze nneerabirira ntya? (Okwefaako) .

Abantu abalina obulwadde bwa essential thrombocythemia bali mu bulabe obw’amaanyi obw’okuzimba omusaayi ne/oba okuvaamu omusaayi mu ngeri etaali ya bulijjo. Waliwo ebintu ebiwerako by’oyinza okukola okukendeeza ku bulabe buno:

• Weewale ddala okunywa ssigala: Abantu abanywa sigala bali mu bulabe bwa maanyi obw’okulwala omusaayi. Bw’oba ​​onywa sigala, noonya obuyambi okulekera awo.
• Kuuma omugejjo omulungi: Abantu abagejjulukuka bali mu bulabe bwa maanyi obw’okulwala omusaayi. Noonya amagezi okuva ew’omukugu mu by’endya era wettanire endya ennungi.
• Dduyiro buli kiseera: Dduyiro akendeeza ku bulabe bw’okuzimba omusaayi.
• Fuga endwadde endala zongera obulabe bw’okuziyira omusaayi: Bw’oba ​​olina embeera nga sukaali oba puleesa, zifuge bulungi.
• Weetegereze obulamu bwo okutwalira awamu: Oluusi embeera eno eyinza okubaawo nga tewali bubonero, n’olwekyo buuza omusawo obubonero bw’olina okwegendereza.

Ddi lwe nnina okulaba omusawo? Ddi lwe nnina okugenda mu kisenge ky’abalwadde ab’amangu?

Bw’oba ​​olina embeera eno, kikulu nnyo okugenda okwekebejjebwa buli kiseera. Kino kijja kusobozesa omusawo wo okulondoola embeera yo, okukebera emiwendo gy’obutoffaali obukola omusaayi, n’okukola enkyukakyuka zonna ezeetaagisa mu bujjanjabi. Mu mbeera ey’amangu, ekyo kitegeezaBw’olaba obubonero bw’okulwala omutima oba okusannyalala, olina okukuba ku ssimu 911 mu bwangu n’ogenda mu ddwaaliro. Obubonero bw’okulwala omutima buyinza okuli:

• Obulumi mu kifuba oba okunyiga (angina).
• Okukaluubirirwa okussa.
• Okuwulira ng’oziyira oba ng’olubuto lutabuse.
• Omutima okukuba amangu (okukuba omukka).
• Okuwulira nga tolina mirembe oba ng’olinga alina ekibi ekigenda okubaawo.
• Okutuuyana.
• Okuziyira (vertigo), okulaba obubi oba okubulwa amagezi.

Abakyala bayinza okufuna obubonero obw’enjawulo:

• Obukoowu obuyitiridde n’obuteebaka.
• Obuzibu mu kussa (dyspnea).
• Obulumi mu mugongo, ebibegabega, mu bulago, mu mikono oba mu lubuto.
• Okusesema.

Obubonero bw’okusannyalala buyinza okuli:

• Okuziyira oba okunafuwa okw’amangu ku ludda olumu olw’omubiri (ffeesi, omukono).
• Obuzibu obw’amangu okwogera.
• Okukaluubirirwa okw’amangu okulaba mu liiso erimu oba gombi.
• Okuziyira ennyo, okukaluubirirwa okutambula, okubulwa bbalansi.
• Obulumi bw’omutwe obw’amaanyi obujja mu bwangu awatali nsonga.

Bibuuzo ki by’osaanidde okubuuza omusawo?

Olw’okuba obulwadde bwa essential thrombocythemia bulwadde obutatera kulabika, oyinza okuba n’ebibuuzo bingi ku bulwadde. Bw’olaba omusawo, tolwawo kubuuza bibuuzo nga bino:

• Lwaki kino kyantuukako?
• Sirina bubonero mu kiseera kino. Obubonero bunaalabika ddi?
• "Okulinda n'obwegendereza" kitegeeza ki?
• Eddagala ki ly’onteesa?
• Nnaaba nnina okumira eddagala obulamu bwange bwonna?

Obubaka Obutwala Awaka

Okay, kale ka nkubuulire kino kikuyamba okujjukira ezimu ku nsonga enkulu okuva mu bye twogeddeko.

Essential Thrombocythemia bulwadde bwa musaayi obutatera kulabika, obuva ku buzaale nga mu busimu bw’amagumba bukola obutoffaali bw’omusaayi bungi obuyitibwa platelets. Kino kyongera obulabe bw’okuziyira omusaayi, okulwala omutima n’okusannyalala.

Wadde nga tekisobola kuwona ddala, ng’ofunye obujjanjabi obutuufu n’obuwagizi bwo, osobola okufuga embeera eno obulungi, okukendeeza ku bizibu ebivaamu, n’okubeera n’obulamu obwa bulijjo. N’olwekyo, bw’oba ​​olina okubuusabuusa kwonna ku nsonga eno, oba bw’oba ​​olina obubonero obutali bwa bulijjo, genda mangu omusawo amagezi. Si ggwe wekka, era waliwo abasawo abajja okukuyamba mu lugendo luno. Essential Thrombocythemia, Platelets, Okuzimba omusaayi, Obusigo bw’amagumba, Endwadde z’omusaayi, Enkyukakyuka mu buzaale, Kookolo