Fibrosarcoma: Ka tuyige ebisingawo ku kookolo ono atatera kulabika

Bw’olaba ekizimba oba ekizimba ekipya ku mubiri gwo naddala ku kigere oba ku mukono gwo olowooza ki? Ebiseera ebisinga, tulowooza nti kya bulijjo ne tukibuusa amaaso. Naye oluusi, n’ekintu ekitono ng’ekyo kiyinza okuba ekintu kye twetaaga okussaayo omwoyo. Leero, tugenda kwogera ku kookolo atatera kulabika nnyo ayinza okulabika ng’ekizimba. Kino kiyitibwa fibrosarcoma.

Mu ngeri ennyangu, fibrosarcoma kye ki?

Fibrosarcoma kika kya kookolo ekitatera kulabika era abeera mu bitundu ebigonvu. Mu busawo, kino tukiyita sarcoma. Kati oyinza okuba nga weebuuza nti soft tissue kye ki. Kyangu nnyo. Ye bitundu by’omubiri ebigatta n’okukwata awamu ebitundu by’omubiri gwaffe eby’enjawulo. Okubeera omutuufu, ebintu ng’emisuwa n’emisuwa ebigatta ebintu ng’amagumba n’ebinywa mu mubiri gwaffe bya bitundu bino ebiyunga.

Kookolo wa fibrosarcoma atera okukula mu bitundu ebigonvu munda mu mubiri. Businga kubeera mu magulu (okwetooloola eggumba ly’ekisambi oba ery’ekisambi), emikono egya waggulu, amaviivi oba omugongo. Era tebutera kukula mu mutwe oba mu bulago. Oluusi, kookolo ono era asobola okukula mu magumba oba mu bitundu ebiyunga ebiwuzi ebibikka amagumba.

Singa ggwe oba omwana wo mufuna obulwadde buno, ekiddako kisinziira ku bintu bingi. Emyaka gyo, obunene bwa kookolo, ne gy’ali byonna bijja kukola kinene. Omusawo wo ajja kukunnyonnyola buli kimu okusinziira ku ky’ozudde.

Kino kirina ebika bibiri ebikulu.

Fibrosarcoma esobola okwawulwamu ebika bibiri ebikulu. Ebika bino ebibiri bya njawulo nnyo ku birala.

Bubonero ki obulaga obulwadde buno?

Ebiseera ebisinga kitwala akaseera obubonero bwa fibrosarcoma okulabika. Olw’okuba ebizimba bino bikula mu bitundu ebigonvu munda mu mubiri, oyinza obutalaba kintu kyonna okutuusa ng’ekizimba kikuze ekinene okusobola okunyigiriza obusimu oba omusuwa oguli okumpi.

Buno bwe bubonero obutera okulabibwa:

• Ekizimba ekigonvu ekitaluma oba ekiruma katono: Kino kiyinza okubaawo ku magulu, emikono oba ku mugongo.
• Okuwulira okuwunya oba obulumi obw'amaanyi, obufumita: Oluusi tugamba nti "ppini n'empiso." Kino kiyinza okuba nga kiva ku puleesa ku busimu obuli okumpi n’ekizimba.
• Okuzimba okutali kwa bulijjo: Okuzimba okw’ekika kino kuyinza okubaawo ng’ekizimba kinyigiriza emisuwa.

Obubonero buno buyinza okufaananako n’obw’embeera endala, ezitali za maanyi nnyo, n’olwekyo omusawo yekka y’asobola okumanya obulungi oba enkyukakyuka zino ziva ku fibrosarcoma oba embeera endala eya bulijjo, etali ya kookolo (ennyangu).

Biki ebivaako n’ebiyinza okuvaako obulwadde bwa fibrosarcoma?

Abanoonyereza tebannaba kukakasa kiki ddala ekivaako obulwadde bwa fibrosarcoma. Kyokka, kirowoozebwa nti enkyukakyuka mu buzaale mu butoffaali zikola kinene. Mu ngeri ennyangu, enkyukakyuka zibaawo mu DNA mu butoffaali bwaffe. Enkyukakyuka zino zireetera obutoffaali okwawukana amangu era nga tebufugibwa, ne bukola ebizimba bya kookolo.

Enkyukakyuka mu buzaale eya bulijjo ezuuliddwa mu fibrosarcoma y’abaana naddala. Ebitundu nga 90% ku bino byekuusa ku bizibu mu famire y’obuzaale bwa NTRK. Obuzaale buno bwe butakola bulungi, ebizimba bya kookolo bisobola okuvaamu.

Ensonga ezongera akabi

Abanoonyereza bakizudde nti embeera ezimu ez’obuzaale ziyinza okwongera ku bulabe bw’okufuna obulwadde bwa fibrosarcoma.

• Obulwadde bwa adenomatous polyposis mu maka
• Obulwadde bwa Li-Fraumeni
• Obulwadde bw’obusimu obw’ekika kya 1 `(Obulwadde bw’obusimu obw’ekika kya 1)`
• Okwewala obulwadde bwa kookolo w’obutoffaali obutono (basal cell carcinoma syndrome).
• Obulwadde bwa Retinoblastoma
• Obulwadde bwa Tuberous sclerosis
• Obulwadde bwa Werner `(Obulwadde bwa Werner)`

Okugatta ku ekyo, embeera endala ezimu ez’obujjanjabi ziyinza okuba nga zikwatagana ne kino:

• Obulwadde bw’amagumba (okufa kw’obutoffaali bw’amagumba olw’omusaayi okukendeera mu magumba) .
• Obulwadde bw’amagumba obutawona (Chronic osteomyelitis) .
• Obulwadde bwa fibrous dysplasia
• Obulwadde bwa Paget obw’amagumba

Waliwo n’ebintu eby’akabi ebikwata ku butonde bw’ensi n’ebyafaayo byo eby’obujjanjabi eby’emabega:

• Nga emabegako yafuna obujjanjabi bw’amasannyalaze okutuuka mu kitundu kookolo w’abeera.
• Okwokya okw’amaanyi awali kookolo.
• Okukwatibwa eddagala erimu, gamba nga thorium dioxide, vinyl chloride oba arsenic.
• Okukwatibwa ebitundu by’ebyuma (e.g. chromium, cobalt, nickel) ebiyingizibwa mu mubiri nga biyita mu kulongoosebwa.

Omusawo akizuula atya kino? (Okuzuula obulwadde)

Abasawo bakola ebigezo ebiwerako okuzuula obulwadde bwa fibrosarcoma. Amawulire agava mu kukeberebwa kuno ge gasalawo omutendera n’ekigero kya kookolo.

• MRI scan (Magnetic Resonance Imaging): Kino kye kigezo ekisinga okukozesebwa okuzuula obulwadde bwa fibrosarcoma. Kiyinza okulaga bulungi obunene n’ekifo ekizimba we kiri, n’okumanya oba kikosa emisuwa oba obusimu.
• CT scan (Computed Tomography scan): Kino kikozesa ebifaananyi ebiwerako ebya X-ray ne kompyuta okukola ebifaananyi eby’ebitundu bisatu (3D) eby’ebitundu byo ebigonvu n’amagumba go.
• Biopsy: Kino kizingiramu okuggya akatundu akatono mu kizimba (core needle biopsy) oba ekizimba kyonna (excisional biopsy) okwekebejjebwa. Omukugu mu by’endwadde akebera ebitundu ebyo mu laboratory okulaba oba birimu obutoffaali bwa kookolo.
• Immunohistochemistry (IHC): Kino kigezo kya njawulo mu laboratory nga kikozesa obutoffaali obuyitibwa antibodies okukakasa oba ekizimba kiri fibrosarcoma oba ekika ekirala ekya kookolo w’ebitundu ebigonvu.

Emitendera gya kookolo gizuulibwa gitya?

Abasawo bagabanya kookolo mu mitendera okuzuula we yasaasaanidde n’engeri gy’ali ey’amaanyi. Kino kitunuulira obunene bw’ekizimba, ekifo we kiri, n’okumanya oba kisaasaanye. Era batunuulira "grade" ya kookolo. Eno y’engeri obutoffaali bwa kookolo gye bulabika ng’obutali bwa bulijjo bwe butunuulirwa mu microscope. Obutoffaali obulabika nga obutali bwa bulijjo butwalibwa nga kookolo "ow'omutindo ogwa waggulu", ayinza okuba ow'amaanyi ennyo.

Omusawo ajja kukunnyonnyola ebinaavaamu oluvannyuma lw’okujjanjabwa, okusinziira ku mutendera gwa kookolo wo.

Bujjanjabi ki obukolebwa ku kino?

Obujjanjabi bw’obulwadde bwa fibrosarcoma businziira ku bintu bingi, omuli obulamu bwo okutwalira awamu, by’oyagala n’ekika kya kookolo.

Obujjanjabi bw’obulwadde bwa fibrosarcoma obw’ekika ky’abantu abakulu

• Okulongoosa: Mu nkola eno abasawo baggyawo ekizimba kya kookolo n’obutundutundu obutono obulamu obukyetoolodde okukakasa nti tewali butoffaali bwa kookolo busigaddewo.
• Radiation Therapy: Radiation therapy eyinza okuweebwa nga tonnalongoosebwa okukendeeza ku kizimba oba okusaanyaawo obutoffaali bwa kookolo bwonna obusigaddewo oluvannyuma lw’okulongoosebwa.
• Obujjanjabi bw’eddagala:Wadde ng’abasawo abamu bawandiika obujjanjabi buno, tebubadde bulungi nnyo ku bulwadde bwa fibrosarcoma obutandika abantu abakulu. Kookolo ow’ekika kino atera obutaddamu bulungi ku bujjanjabi bwa ddagala.

Obujjanjabi bw’obulwadde bwa fibrosarcoma obw’abaana abawere

• Okulongoosa: Mu baana, okulongoosa okuggyamu ekizimba kitera okuwonya ddala obulwadde buno.
• Radiation ne/oba chemotherapy: Obujjanjabi buno bukozesebwa okukendeeza ku bizimba nga tebannalongoosebwa oba okusaanyaawo obutoffaali obusigaddewo oluvannyuma lw’okulongoosebwa. Okwawukana ku ngeri y’omuntu omukulu, fibrosarcomas ezisinga obungi ez’abaana ziddamu bulungi nnyo ku ddagala.
• Obujjanjabi obugendereddwamu: Obujjanjabi buno busobola okukomya obutoffaali okwawukana amangu olw’obuzibu obuli mu ggiini ya `NTRK`. Kino kiyinza okukendeeza ku bizimba n’okwanguyira okulongoosa.

Embeera eri etya oluvannyuma lw’okujjanjabwa? (Okuteebereza)

Ebiva mu bulwadde bwa fibrosarcoma bw’abaana abawere birungi nnyo. Ebisinga ku bino bisobola okuwona ddala nga bigattiddwa wamu n’okulongoosebwa, okukuba amasannyalaze, eddagala eriweweeza ku bulwadde oba obujjanjabi obugendereddwamu. Omuwendo gw’abantu abawangaala mu myaka 10 guli nga 90%. Singa okulongoosa kusobola bulungi okuggyawo obubonero bwonna obwa kookolo, omuwendo ogwo gusemberera ebitundu 100%.

Embeera y’obulwadde bwa fibrosarcoma obutandika abantu abakulu esinga kuzibuwalira. Ebiseera ebisinga, ebizimba bino bizuulibwa nga bimaze okukula ebinene ekimala okukosa obusimu oba okutambula kw’omusaayi. Nga bwe kiri ku kookolo yenna, okuzuula amangu kivaamu ebirungi. Kookolo bw’amala okukula, yeeyongera okukaluba okujjanjaba. Abalwadde nga kimu kya kubiri bayinza okuddamu okufuna obulwadde buno oluvannyuma lw’okujjanjabwa.

Bw’oba ​​olina embeera eno, weerabirira otya?

Abantu bangi bwe bazuuliddwa nti balina kookolo bawulira nga tebalina kye basobola kukola. Emu ku ngeri esinga obulungi ey’okukola ku nneewulira zino kwe kwerabirira ng’ofunye obujjanjabi n’oluvannyuma lw’okujjanjabibwa. Bino bye bimu ku bintu by’osobola okukola:

• Tegeera enteekateeka yo ey’okugoberera: Buuza omusawo wo ky’osuubira mu kiseera ky’okuwona ne ku ssaawa z’okugoberera.
• Dukanya Okweraliikirira: Okukeberebwa buli kiseera ng’omaze okujjanjabwa kikulu okuzuula amangu kookolo azzeemu. Naye era kiyinza okuleetawo okweraliikirira. Yogerako n’omubuulirizi ku nsonga eno.
• Saba obuyambi: Mazima ddala ojja kwetaaga obuyambi mu kiseera ky’obujjanjabi bwo. Abaagalwa bo bayinza okuba nga balinze okukuyamba. Babuulire engeri gy’oyinza okuyambamu.
• Essira lisse ku mize emirungi egy’obulamu: Okulya emmere erimu ebiriisa, okukola dduyiro omumala, n’okwebaka obulungi bikulu nnyo.
• Okuwummula:Obujjanjabi bwa kookolo ne kookolo busobola okukuleetera okuwulira ng’okooye nnyo. Tegeka okufuna ekiwummulo ekinene nga bwe kisoboka ng’ojjanjabibwa.
• Lwanyisa situleesi: Ebintu ng’okufumiitiriza, okukola dduyiro ow’okuwummulamu, n’okukola dduyiro w’okussa ennyo bisobola okuyamba okukendeeza ku situleesi.

Ddi lwe weetaaga okulaba omusawo?

Oluvannyuma lw’okujjanjabwa, ebiseera ebisinga ojja kulaba omusawo buli luvannyuma lwa myezi esatu okumala emyaka ebiri egisooka n’oluvannyuma mu bbanga erisingako katono okumala emyaka ena oba etaano. Singa fibrosarcoma eddamu, ekitera okubaawo mu myaka etaano egisooka, enteekateeka eno ejja kuyamba okuzuula okuddamu kwonna nga bukyali.

Olina okutuukirira omusawo wo buli lw’ofuna ebizimba ebipya oba obulumi obupya.

Ddi lwe weetaaga okugenda mu kitongole ekijjanjaba abalwadde ab’amangu (ETU)?

Enzijanjaba nnyingi eza kookolo zikosa abaserikale b’omubiri, ekyongera obulabe bw’okukwatibwa obulwadde. Wano waliwo obubonero obuyinza okukwetaagisa okugenda mu kitongole ky’abalwadde ab’amangu (ETU) ng’ojjanjabibwa:

• Omusujja gwa diguli 38.3 (100.4 Fahrenheit) oba okusingawo.
• Okuwulira ennyogovu n’okukankana.
• Okusesema nga kuliko omusulo.
• Obulumi mu lubuto.
• Ekiddukano ekitaggwaawo.
• Okuziyira n’okusiiyibwa okutambula obutasalako.