Olina phosphate omungi mu mubiri gwo? Ka twogere ku bulwadde bwa hyperphosphatemia!

Wali weebuuzizza lwaki oluusi ebintu ebimu mu mibiri gyaffe biba waggulu okusinga bwe birina okuba? Mpozzi omusawo akugambye nti olina ekirungo kya phosphate ekisusse mu musaayi. Oba olyawo wali owuliddeko. Kino kye tuyita hyperphosphatemia. Wadde erinnya lino liyinza okuwulikika ng’ery’ekyewuunyo katono, bwe tulitegeera bulungi, tekirina kye tweraliikiriza.

Ddala hyperphosphatemia kye ki?

Mu ngeri ennyangu, obulwadde bwa hyperphosphatemia bwe buba ng’omusaayi gwo gulina ekirungo ekisusse ekiyitibwa phosphate. Phosphate kiriisa kikulu nnyo eri emibiri gyaffe. Kiyamba okukuuma amagumba n’amannyo gaffe nga binywevu, kiwa obutoffaali bwaffe amaanyi, era kiyamba okukola obuwuka obuyitibwa cell membranes.

Lowooza bw’ati, phosphate eringa bbaatule entono mu mubiri gwaffe. Bino okusobola okukola obulungi, byetaaga okuba n’amasannyalaze. Phosphate kye kimu ku bikozesebwa eby'amasannyalaze ng'ebyo . Electrolytes ze minerals eziyinza okutwala oba positive (+) oba negative (-) charge y’amasannyalaze nga zisaanuuse mu mazzi oba mu mazzi nga omusaayi gwaffe. Kale, okukuuma omutindo gwa phosphate guno nga gukwatagana kikulu ku mirimu mingi mu mubiri. Otegedde?

Ani asinga okulwala embeera eno?

Mu butuufu omuntu yenna asobola okufuna embeera eno eyitibwa hyperphosphatemia. Wabula kisinga kubeera mu bantu abalina obuzibu mu kibumba. Okusingira ddala, abantu abalina obulwadde bw’ekibumba obutawona (CKD) , naddala abo abalina obulwadde obw’amaanyi, oba abalina obulwadde bw’ekibumba obulemererwa, batera okufuna embeera eno.

Kati, waliwo ebintu ebiyinza okuvaako endwadde z’ekibumba. Bw’oba ​​olina ekimu oba ebisingawo ku bino wammanga, oba mu bulabe obutono obw’okufuna obulwadde bw’ekibumba era, okuyita mu byo, hyperphosphatemia:

• Bw’oba ​​olina obulwadde bwa sukaali (Diabetes Mellitus) .
• Bw’oba ​​olina puleesa (puleesa) .
• Bwoba olina obulwadde bw'omutima .
• Singa omuntu mu maka go abadde n’obulwadde bw’ekibumba (ekitegeeza nti buyinza okuba obw’obuzaale).
• Singa wabaawo ekitali kya bulijjo mu nsengeka y’ensigo zo.
• Bw’oba ​​wa kika kya African American, Hispanic, Asian, oba Native American (abantu abali mu mawanga gano batera okufuna obulwadde bw’ekibumba).
• Bwoba olina emyaka egisukka mu 60 .
• If you have been a frequent user of pain relievers for a long time , naddala eddagala eriziyiza okuzimba eritali lya steroid (NSAIDs), eriyinza okugulibwa ku kkawunta ku dduuka ly’eddagala.

Embeera eno ya bulijjo etya?

Bw’otunuulira abantu abasinga obungi mu nsi, tekitera kubaawo nnyo okubeera n’obulwadde bwa hyperphosphatemia yokka. Ekyo kitegeeza nti phosphate yeeyongera mu musaayi yokka. Naye, nga bwe nnagambye emabegako, bw’oba ​​olina obulwadde bw’ekibumba obutawona , naddala nga bwa maanyi, embeera eno etera nnyo. Mu ngeri ey’obukambwe, abantu nga 70% abalina obulwadde obw’amaanyi obw’ekibumba obutawona bazuuliddwa nga balina obulwadde bwa hyperphosphatemia.

Kiki ekituuka ku mubiri nga phosphate yeeyongedde?

Twayogedde emabegako ku ngeri phosphate gy’ayamba okunyweza amagumba n’amannyo gaffe, okuwa obutoffaali amaanyi, n’okuyamba okuzimba obuwuka obuyitibwa cell membranes. Ekyo kituufu. Naye, okufaananako ekintu kyonna, bwe kisusse kiyinza okuleeta obuzibu.

Teebereza, singa phosphate mu musaayi gwo egenda waggulu nnyo, etandika okufulumya calcium okuva mu magumba go. Kiki ekibaawo olwo? Amagumba ganafuwa era ne gakutuka.

Tekikoma awo, naye phosphate ono asusse asobola okuleetera okutondebwawo kwa calcium mu maaso go, amawuggwe, omutima n’emisuwa gyo. Kino kya bulabe katono. Kubanga ekiseera bwe kigenda kiyitawo, ebitereke bino byongera ku bulabe bw’okulwala omutima, okusannyalala , n’okufa.

Bubonero ki obulaga obulwadde bwa Hyperphosphatemia?

Ebiseera ebisinga, bw’oba ​​olina obulwadde bwa hyperphosphatemia bwokka, tolaba bubonero bunene. Ekyo kitegeeza nti oyinza obutasooka kukimanya nti olina ekirungo kya phosphate ekisusse mu mubiri gwo. Wabula nga bwe twayogeddeko, phosphate ono bwe yeeyongera, asobola okuvaako calcium okubula okuva mu magumba go n’omusaayi. Ekyo kiyitibwa hypocalcemia . Ekyo kitegeeza nti omuwendo gwa kalisiyamu mu musaayi gukendeera.

Kale, ebiseera ebisinga, obubonero bw’obulwadde bwa hyperphosphatemia bwe bumu n’obwo obuva ku hypocalcemia. Laba oba bino biwulikika ng’ebimanyiddwa gy’oli:

• Okuzimba ebinywa.
• Emisumaali egy’ekika kya brittle.
• Olususu olukalu.
• Enviiri enzirugavu okusinga enviiri zo eza bulijjo.
• Obuzibu mu kujjukira .
• Okunyiiga.
• Okuwunya mu mimwa, olulimi, engalo, ne/oba ebigere.
• Oluusi kijja nga fit (okukonziba).
• Obutabeera bwa bulijjo mu kukuba kw’omutima, kwe kugamba, obutatambula bulungi.

Lwaki obulwadde bwa hyperphosphatemia bubaawo?

Wandibaawo ensonga eziwerako eziviirako kino. Ebikulu bye bino:

• Obulwadde bw’ekibumba obutawona obw’omulembe. Kino kye kisinga okuvaako. Ensigo bwe zitakola bulungi, tezisobola kufulumya phosphate ayitiridde mu mubiri.
• Obulwadde bwa Hypoparathyroidism. Eno mbeera ng’endwadde za parathyroid zikola obusimu obutono ennyo obuyitibwa parathyroid hormone, obufuga emiwendo gya calcium ne phosphate mu mubiri.
• pH y’omusaayi gwo eri wansi okusinga eya bulijjo (ekitegeeza nti omusaayi gwo gusingako asidi). Kino kiyinza okuba nga kiva ku mawuggwe go tegasobola kugoba kaboni dayokisayidi yenna akolebwa mu mubiri gwo. Kino kiyitibwa obulwadde bwa asido mu kussa .
• Okukendeera kwa pH mu musaayi olw’ensonga endala ( metabolic acidosis ).

Ng’oggyeeko bino, wadde nga tebitera kubaawo, hyperphosphatemia nayo esobola okubaawo olw’ensonga zino wammanga:

• Obulwadde bwa ketoacidosis obuva ku ssukaali.
• Okwonooneka kw’ebinywa ( rhabdomyolysis ).
• Obulwadde obw’amaanyi ( sepsis ).
• Crush injury (obuvune obuva ku kintu ekizito okugwa ku mubiri oba ekintu ekinyiga ku mubiri okumala ebbanga eddene).
• Omubiri gwo teguddamu bulungi busimu bwa parathyroid ( pseudohypoparathyroidism ).
• Okuyingiza phosphate omungi mu mubiri gwo, oba okuva mu mmere gy’olya oba okuyita mu enema .

Ensonga ki esinga okubeerawo?

Nga bwe nnagambye emabegako, ekisinga era ekisinga okuvaako obulwadde bwa hyperphosphatemia bwe bulwadde bw’ekibumba obutawona obw’amaanyi.

Buno bulwadde busiigibwa?

Nedda, obulwadde bwa hyperphosphatemia si bulwadde obusiigibwa. Tosobola kubusaasaanya ku balala. Wabula si bulijjo nnyo, esobola okutambulira mu maka olw’ensonga z’obuzaale.

Kino abasawo bakizuula batya?

Omusawo asobola okumanya oba olina obulwadde bwa hyperphosphatemia. Ajja kutwala ebyafaayo byo eby’obujjanjabi , akukebere omubiri , era akubuuze ku bubonero bwo, endya yo, n’eddagala lyonna ly’omira. Okusobola okumanya ddala phosphate ki, ojja kwetaaga okwekebeza omusaayi .

Mu kiseera ky’okukebera omusaayi, omusawo oba nnansi ajja kuggya omusaayi omutono okuva mu musuwa oguli mu mukono gwo ng’akozesa empiso entono (21 gauge, entono katono okusinga ensonga y’empeta eya bulijjo). Sampuli eno ey’omusaayi esindikibwa mu laabu okukebera obungi bwa phosphate obuli mu musaayi gwo. Singa phosphate yo esukka miligiraamu 4.5 buli desilita (4.5 mg/dL) y’omusaayi, ., ekyo kitegeeza nti olina obulwadde bwa hyperphosphatemia.

Singa ozuulibwa nti olina embeera eno, omusawo ayinza okulagira okukeberebwa ebirala okukebera embeera y’ensigo zo. Mu bino biyinza okuli:

• Okwongera okukeberebwa omusaayi.
• Okukebera okukebera oba puloteyina mu musulo.
• Okukebera (Ultrasound scan) mu ngeri ya ultrasound .
• Okukebera MRI .
• Okukebera CT .
• Kidney biopsy ( okutwala akatundu akatono ak’ekibumba okukeberebwa).

Bujjanjabi ki obukolebwa ku kino?

Obujjanjabi bw’obulwadde bwa hyperphosphatemia businziira ku kiki ekivaako phosphate okuzimba mu musaayi gwo. Emmere n’eddagala erimu nabyo bisobola okuvaako phosphate okubeera omungi. Kino bwe kibaawo, kiyinza okwetaagisa okussa ekkomo oba okulekera awo okulya emmere oba eddagala erimu. Oba, oyinza okwetaaga okukyusa n’odda ku ddagala ery’enjawulo eririna phosphate omutono.

Ekisinga obukulu kwe kugoberera ddala ebiragiro by’omusawo.

Omusawo ayinza okukuwa eddagala erikendeeza ku bungi bwa phosphate omubiri gwo gwe gunyiga. Kino kitegeeza nti phosphate omungi afulumizibwa mu musulo gwo (omusulo). Eddagala lino mulimu:

• Sevelamer (Ekirungo kya Sevelamer - RenaGel®) .
• Lanthanum (Lanthanum - Fosrenol®) (Ekitundu ky’Omubiri) .
• Ekirungo kya kalisiyamu (Calcium acetate - Calphron®) .

Singa ekirungo kya phosphate kibeera kinene olw’ekibumba okulemererwa, omusawo ayinza okukutandika okulongoosebwa . Dialysis ekola ekyo ekibumba kyo kye kiteekeddwa okukola. Kwe kugamba, eggyamu amazzi n’ebisasiro ebisukkiridde omuli ne phosphate mu musaayi gwo.

Emmere ki erimu ekirungo kya phosphorus ekingi?

Waliwo emmere n’ebyokunywa ebiwerako ebirimu ekirungo kya phosphorus ekingi – ekintu ekivaamu phosphate. Kikulu okumanya bino naddala ng’olina obulwadde bwa hyperphosphatemia.

• Amata n’amata, gamba ng’amata, kkeeki ezirongooseddwa, ne yogati.
• Ebimu ku byokunywa ebirimu kaboni (ebyokunywa ebya soda pop/fizzy).
• Ennyama erongooseddwa ( nga sosegi ne bacon).
• Emmere ey’amangu.
• Emmere ey’akawoowo ( ebintu ebipakiddwa nga chips, bisikiiti).
• Entangawuuzi.
• Empeke enzijuvu , nga muno mulimu eŋŋaano, oats, n’omuceere (naddala ebirimu ebikuta).
• Ebijanjaalo.
• Entangawuuzi.

Omusawo wo ayinza okuba nga yakugambyeOjja kusindikibwa ew'omusawo w'emmere y'ekibumba . Bano be bantu abakuguse mu ngeri y’okuddukanyaamu emmere yo okuwagira obulamu bw’ekibumba. Zijja kukuyamba okukola enteekateeka y’emmere ey’enjawulo (endya y’ekibumba) ekoma ku bungi bwa phosphate mu mubiri gwo.

Waliwo engeri gye tuyinza okuwona embeera eno?

Engeri esinga okuziyiza obulwadde bwa hyperphosphatemia kwe kufaayo ku bulamu bw’ekibumba kyo n’okumanya obungi bwa phosphate ne calcium by’olya. Bw’oba ​​olowooza nti oyinza okuba mu bulabe bw’okulwala embeera eno, yogerako n’omusawo wo. Ayinza okukusindika ew'omusawo w'ekibumba . Omusawo w’ekibumba musawo mukugu mu mbeera ezikosa ensigo.

Biseera ki ebisinga obulungi okulaba omusawo?

Bw’oba ​​okimanyi nti olina obulwadde bwa hyperphosphatemia, era n’ofuna obubonero bw’obulwadde bw’ekibumba oba okulemererwa kw’ekibumba, laba omusawo mu bwangu. Tolwawo.

Bibuuzo ki by’osaanidde okubuuza omusawo?

Bw’ogenda okulaba omusawo, kikulu nnyo okubuuza ebibuuzo bino:

• Omanya otya mu bukakafu oba nnina obulwadde bwa hyperphosphatemia?
• Bwemba sirina mbeera eno, mbeera ki endala ez’obujjanjabi ze nnyinza okuba nazo?
• Omutindo gwa phosphate mu musaayi omulungi gwe guliwa?
• Eddagala ki ly’onteesa?
• Okwetaaga eddagala eriwandiikiddwa okusobola okufuna eddagala eryo, oba osobola okuligula ku dduuka ly’eddagala?
• Mmere ki n’ebyokunywa bye sisaanidde kulya wadde okunywa?
• Nnidde phosphorus mmeka buli lunaku?
• Osobola okunjuliza ew’omusawo w’emmere y’ekibumba?
• Nsaana ndabe omusawo w’ekibumba oba omusawo omulala omukugu?

Njawulo ki eriwo wakati wa Hyperphosphatemia ne Hypocalcemia?

Bino ebibiri biyinza okubuzaabuza katono, kale katulambule.

Hyperphosphatemia bwe buba nga phosphate mu musaayi gwo esukkiridde .

Hypocalcemia bwe buba nga calcium mu musaayi gwo ekendedde nnyo .

Ebiseera ebisinga, embeera eno eyitibwa hypocalcemia ebaawo ng’ekizibu ekiva mu mbeera endala ey’obujjanjabi. Obulwadde bwa hyperphosphatemia kye kimu ku bivaako okukendeera kw’omusaayi.

Obubaka Obusembayo Okutwala Awaka

Okay, kale twogedde nnyo ku hyperphosphatemia. Mu ngeri ennyangu, kwe kwongera ku muwendo gwa phosphate mu musaayi gwo. Wadde nga si kya bulijjo nnyo mu bantu abasinga obungi mu nsi, kiyinza okuba nga kya bulijjo nnyo mu bantu abalina obulwadde bw’ekibumba obutawona oba okulemererwa kw’ekibumba .

Ebiseera ebisinga, mu kusooka tewabaawo bubonero bwa njawulo. N’olwekyo, abantu bangi bakitegeera nti balina embeera eno oluvannyuma lw’obubonero obulala okulabika, mpozzi nga hypocalcemia.

Bw’okizuula nti olina obulwadde bwa hyperphosphatemia naddala nga bakugambye nti weetaaga okulongoosebwa, kya bulijjo okuwulira okweraliikirira n’okutya. Tewali kibi mu kuba na nneewulira ezo. Yogerako n’omusawo wo ku bibuuzo byonna oba ebikweraliikiriza by’olina. Bajja kuddamu ebibuuzo byo, bakuwe obuyambi bwe weetaaga, era bakuwe amagezi ku ngeri y’okugumira obulungi embeera eno. Jjukira nti toli wekka!

` Hyperphosphatemia, Phosphate, Obulwadde bw’ekibumba, Obulwadde bw’ekibumba obutawona, Hypocalcemia, Dialysis