Wali weebuuzizzaako engeri emibiri gyaffe gye girwanyisa omulabe nga akawuka nga kayingira mu mibiri gyaffe? Emibiri gyaffe girina enkola ey’okwekuuma eyeewuunyisa. Ekimu ku ‘bikozesebwa ebiraga obubonero’ ebikulu mu nkola eyo kiyitibwa interferon. Mu butuufu zino puloteyina emibiri gyaffe gye gikola. Ate era, eddagala lya interferon erikolebwa mu ngeri ey’ekikugu aweebwa ng’eddagala ng’eddagala erijjanjaba embeera ezimu ez’obujjanjabi. Kino ka twogere mu ngeri ennyangu leero.
Mu ngeri ennyangu, interferon kye ki?
Teebereza nti omubiri gwaffe kibuga kinene. Ekibuga kino kikuumibwa eggye eriyitibwa abaserikale b’omubiri. Kati omulabe, gamba ng’akawuka oba akatoffaali ka kookolo, ayingira mu kibuga kino. Mu kaseera ako, obutoffaali (okugeza, obutoffaali obweru) obubeera mu kitundu omulabe ono w’abeera, bufulumya akabonero akalaga okulabula. Puloteeni egaba akabonero ako eyitibwa interferon.
Erinnya lino linyuma nnyo. Bino "bitaataaganya" obuwuka nga akawuka okweyongera munda mu mubiri, kwe kugamba, okuva mu kufuuka obulwadde. Eno y’ensonga lwaki ziyitibwa ‘interferons’.
Kale, wadde nga bino bikolebwa mu butonde mu mibiri gyaffe, era bikolebwa mu ngeri ey’ekikugu bannassaayansi mu laboratory ne bikozesebwa ng’eddagala erijjanjaba endwadde ez’enjawulo. Interferon yasooka kutondebwawo mu ngeri eno mu 1986 okujjanjaba ebika bya kookolo ebimu.
Interferon ekola etya?
Interferons ziringa layini esooka ey’okwekuuma mu nkola y’omubiri gwaffe ey’okwekuuma. Akatoffaali bwe kakwatibwa akawuka, akatoffaali ako kakola ebirungo ebiyitibwa interferons ne kaweereza okulabula eri obutoffaali obulamu obukwetoolodde. Nga bw'ogamba nti, "Wano w'ajja omulabe, naawe kola ku by'okwerinda byo!"
Akabonero kano bwe kafunibwa, obutoffaali obulala nabwo bwetegekera okulwanyisa akawuka kano. Interferon era eyita abalwanyi abalala mu baserikale baffe (nga ekika ekirala ekya puloteyina ekiyitibwa cytokines) okwegatta ku lutalo luno.
Kino kye kimu ekibaawo ku ddagala lya interferon eriweebwa mu ngeri ey’ekikugu.
- Kigamba abaserikale b'omubiri "okusaanyaawo obutoffaali buno."
- Kikomya obutoffaali bwa kookolo ne akawuka okwawukana n’okusaasaana.
- Ayamba obutoffaali obulamu okulwanyisa yinfekisoni.
Waliwo ebika bya interferons ebikulu bisatu.
- Ekirungo kya Interferon-alpha
- Ekirungo kya Interferon-beta
- Ekirungo kya Interferon-gamma
Endwadde ki ezijjanjabwa n’eddagala lya interferon ng’eddagala?
Ebika bya interferons eby’enjawulo bikozesebwa okujjanjaba embeera ez’enjawulo. Laba ekipande wansi okufuna ennyonyola ennyangu okutegeera.
| Ekika kya interferon | Embeera ezijjanjabwa |
|---|---|
| Ekirungo kya Interferon-alpha |
|
| Ekirungo kya Interferon-beta | Ku bika by’obulwadde obw’enjawulo obw’abaserikale b’omubiri obuyitibwa Multiple Sclerosis (MS). Kino kiyamba okukendeeza ku buzimba mu busimu mu bwongo n’omugongo. |
| Ekirungo kya Interferon-gamma |
|
Obujjanjabi buno buweebwa butya?
Omusawo wo ajja kutera okukuwa eddagala lino ng'empiso wansi w'olususu oba mu kinywa . Oluusi kiyinza n’okuweebwa ng’ekifumbiddwa mu musuwa mu mukono gwo. Obujjanjabi buno butera kuweebwa mu ddwaaliro oba mu ddwaaliro. Naye mu mbeera ezimu, omusawo oba nnansi ajja kukuyigiriza engeri gy’oyinza okwekubamu empiso awaka.
Ekika ky’eddagala eriweebwa, omuwendo gw’eddagala n’ebbanga lye liweebwa bijja kusinziira ku mbeera gy’olimu.
Biki ebiyinza okuva mu bujjanjabi bwa interferon?
Okufaananako n’eddagala lyonna ery’amaanyi, eddagala lya interferon liyinza okuba n’ebizibu n’ebizibu. Naye jjukira nti omusawo wo akuteesa ku bujjanjabi buno kubanga emigaso egivaamu gisinga wala akabi akayinza okuvaamu.
Totya kuteesa mu lwatu ku buzibu buno bwonna n’omusawo asobole okukola emitendera egyetaagisa.
| Ebizibu ebitera okuvaamu n’ebizibu ebiyinza okuvaamu eby’amaanyi | |
|---|---|
| Ebizibu ebitera okubaawo abantu bangi bye bafuna | |
| Obubonero obulinga obwa ssennyiga | Obubonero ng’omusujja, okusiiyibwa, okulumwa omubiri, okulumwa omutwe, n’okuziyira biyinza okulabika nga wayise essaawa ntono ng’omaze okumira eddagala. Bino bitera okukka mu ssaawa 24 zokka. |
| Ebizibu ebirala ebivaamu | Okusiiyibwa kw’olususu, okukoowa ennyo, okugwa kw’enviiri (alopecia), obutayagala mmere, n’okulemererwa okusituka mu basajja bisobola okubaawo. |
| Ebizibu ebiyinza okuba eby’amaanyi ebyetaagisa okufaayo ennyo | |
| Ebizibu by’omutima | Abantu abamu bayinza okufuna puleesa okukka, omutima nga tegukuba bulungi oba nga gukuba mangu. Omusawo wo ajja kweraliikirira naddala singa oba olina obulwadde bw’omutima. |
| Ebizibu by‟obulamu bw‟obwongo | Abantu abamu bayinza okufuna ekiwuubaalo oba endowooza embi ku bulamu. Bw’oba olina edda ekizibu ky’obwongo, omusawo ajja kukulondoola nnyo mu kiseera ky’obujjanjabi buno. |
| Ebizibu by’amaaso | Bw’oba olina embeera nga diabetic retinopathy, eddagala lino liyinza okubyongera okubwonoona. N’olwekyo, omusawo ajja kukuwa amagezi okukeberebwa amaaso go nga tonnafuna bujjanjabi era nga tonnafuna bujjanjabi. |
| Obuzibu mu thyroid | Abantu abamu bayinza okufuna embeera nga endwadde ya thyroid ekola ennyo (hyperthyroidism) oba endwadde ya thyroid ekola obubi (hypothyroidism). |
| Ebizibu by’amawuggwe | Bw’oba olina endwadde z’amawuggwe nga obulwadde bw’amawuggwe oba ekifuba, eddagala lino liyinza okubwonoona. |
Obubaka Obutwala Awaka
- Interferon nkola ya butonde mu mubiri gwaffe erwanyisa obuwuka n’obutoffaali bwa kookolo.
- Interferon, ekolebwa mu laboratory, ddagala lya maanyi erijjanjaba endwadde ez’amaanyi nga hepatitis, multiple sclerosis (MS), ne kookolo omu.
- Obujjanjabi buno buyinza okuvaako ebizibu, gamba ng’omusujja. Waliwo n’akabi akatono ak’ebizibu eby’amaanyi. Kikulu okukimanya ku kino.
- Wulira nga oli waddembe okwogera n’omusawo wo ku buzibu bwonna oba ebizibu by’oyinza okufuna.
- Tokyusa mu ddoozi oba okulekera awo okumira eddagala lyo nga tolina magezi ga musawo. Omusawo wo alonze obujjanjabi buno ku lw’obulungi bwo.
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