Obulwadde bwa myotonia bukaluubiriza omubiri gwo? Ka twogere ku nsonga eno!

Oluusi owulira ng’omukono gwo, ekigere oba ekinywa kyonna mu mubiri gwo kikalubye era nga tosobola kuwummula mangu nga bw’olowooza? Nga bw’okwatagana n’omuntu mu ngalo n’ofuna obuzibu okusika omukono, oba bw’ogezaako okusituka mu ntebe, kitwala akaseera. Buno bwe bumu ku bubonero bw’embeera eyitibwa myotonia. Teweeraliikiriranga, kino tujja kukyogerako mu bujjuvu.

Myotonia kye ki?

Mu ngeri ennyangu, myotonia y’ebeera ng’ebinywa byo tebiwummudde mangu oluvannyuma lw’okukonziba. Kuba akafaananyi ng’okwatagana n’omuntu mu ngalo, naye nga kizibu okusika omukono gwo, oba bw’oba ​​otudde wansi n’ogezaako okusituka, amagulu go gawulira nga gakalubye okumala akaseera. Ekyo kye kika ky'ekintu.

Waliwo ebika bya myotonia eby’enjawulo. Buli kika kiva ku nkyukakyuka mu buzaale . Kino kitegeeza nti kiva ku ngeri gye kikwata ku buzaale mu mubiri gwaffe. Mu buli kika, obuzaale obw’enjawulo bukosebwa.

Olw’enkyukakyuka zino ez’obuzaale, myotonia esobola okukosa ebitundu by’omubiri gwo ebirala. Okusinziira ku kika kya myotonia gy’olina, kino kiyinza okukosa:

• Eri ku mutima
• Eri mu mawuggwe
• Ku nkola y’okugaaya emmere
• Eri ku bwongo
• Ku lw’amaaso

Kiyinza okutuuka ku bitundu by’omubiri nga.

Kya bulijjo okuwulira ng’otya ng’ofunye akabonero k’obadde tolinako, ng’okukaluba kw’ebinywa. Oyinza okuba nga weebuuza nti, "Kino kinaayongera okusajjuka?" oba "Kino kinaakwata kitya ku bulamu bwange?" Ekisinga obulungi ky'oyinza okukola kwe kulaba omusawo . Myotonia mbeera etali ya bulijjo, n’olwekyo kiyinza okutwala ekiseera okuzuula ekituufu. Naye mu kiseera kino, omusawo asobola okukuyamba okukendeeza ku kutya kwo n’okuddamu ebibuuzo byo.

Bika ki ebikulu eby’obulwadde bwa myotonia?

Abasawo bagabanya myotonia mu bika bibiri ebikulu: dystrophic ne non-dystrophic . Ebika byombi bikosa obubonero bw’amasannyalaze obufuga okukonziba kw’ebinywa. Naye mu dystrophic myotonia, ekinywa kyennyini kyonoonese. Ekigambo ‘dystrophy’ kitegeeza ‘okunafuwa oba okwonooneka kw’ebitundu by’omubiri mpolampola.’

Obulwadde bw’emisuwa obuyitibwa Dystrophic Myotonia (DM) .

Dystrophic Myotonia (DM) mbeera ng’ebinywa binafuwa ne bikendeera (atrophy) okumala ekiseera, nga bibeera mu kibinja ky’endwadde eziyitibwa muscular dystrophy. Waliwo ebika bibiri ebikulu:

• Myotonic Dystrophy type 1 (DM1) – Kino kye kika ekisinga okubeerawo.
• Obulwadde bwa Myotonic Dystrophy ekika kya 2 (DM2) .

Myotonia etali ya dystrophic

Mu myotonia etali ya dystrophic, ensengekera y’ebitundu by’ebinywa teyonooneka. Ebika ebirala ebimu ebigwa mu kiti kino bye bino:

• Obulwadde bwa Andersen-Tawil
• Okusannyalala buli luvannyuma lwa kiseera nga olina hyperkalemic
• Hypokalemic periodic paralysis ekika kya 1 n’ekika kya 2
• Myotonia congenita – Kino kye kika ky’ekibinja kino ekisinga okubeerawo.
• Obulwadde bwa Paramyotonia obuzaalibwa
• Obulwadde bwa myotonia obw’omukutu gwa sodium

Bubonero ki obulaga obulwadde bwa Myotonia?

Akabonero akakulu ak’obulwadde bwa myotonia bwe butasobola kuwummuza kinywa nga kimaze okukonziba. Obubonero buno busobola okulabika mu buwere, mu buto oba mu bukulu, okusinziira ku kika kya myotonia.

Obubonero obulala obutera okulabika obuyinza okulabibwa mulimu:

• Enkyukakyuka mu ndabika y’ebinywa byo – okugeza, okugaziwa kw’ebinywa (hypertrophy) oba okunafuwa kw’ebinywa (hypotonia) .
• Obukoowu .
• Obulumi mu binywa .
• Obunafu bw'ebinywa .
• Okuwulira ng’ebinywa binywezeddwa, naye okunywezebwa kukendeera ng’otambula oba ng’okola dduyiro (warm-up phenomenon) .

Obubonero obw’enjawulo obw’obulwadde bwa dystrophic myotonia

Buli kika kya dystrophic myotonia kirina obubonero obw’enjawulo. Ebimu ku byokulabirako bye bino:

• Obulumi mu lubuto, okuziyira, ekiddukano, asidi okuddamu, okuzimba.
• Obutabeera bwa bulijjo mu ndabika ya ffeesi (facial dysmorphisms) .
• Cataracts (okuziba ebire mu kulaba kw’eriiso) .
• Hyperglycemia mbeera eva ku buziyiza insulini, ekivaako ssukaali okubeera omungi mu musaayi.
• Obulemu ku magezi .
• Omutima obutakuba bulungi (arrhythmia) oba obuzibu ku bubonero bw’amasannyalaze bw’omutima.
• Enviiri okugwa okuva mu maaso g’omutwe mu basajja (androgenic alopecia) .
• Sleep apnea (okusannyalala mu tulo) .

Bubonero ki obw’abantu abalina obulwadde bwa Periodic Paralysis?

Olina obulwadde bwa hyperkalemic periodic paralysis.Bw’oba ​​olina, oyinza okufuna embeera eringa ey’okusannyalala ng’ebinywa byo bikendeera amaanyi okumala essaawa nga emu oba nnya.

Bw’oba ​​olina hypokalemic periodic paralysis , oyinza okufuna obunafu bw’ebinywa ekiro oba ku makya ennyo. Kino kiyinza okumala okuva ku ssaawa ntono okutuuka ku nnaku ntono.

Kiki ekivaako obulwadde bwa myotonia?

Myotonia eva ku nkyukakyuka eyeetongodde mu emu ku buzaale bwo . Okusobola okusingawo, enkyukakyuka zino ez’obuzaale zikwata ku mikutu gya ion egivunaanyizibwa ku kufuga enkola y’ebinywa byo.

Buli kika kya myotonia kiva ku nkyukakyuka mu ggiini ey’enjawulo. Okugeza, obulwadde bwa myotonic dystrophy type 1 buva ku buzibu obuli mu ggiini ya DMPK . Myotonia congenita eva ku buzibu ku ggiini ya CLCN1 . Enkyukakyuka eno ey’obuzaale osobola okugisikira okuva ku bazadde bo omu oba bombi. Oba, kiyinza okukula mu ngeri ey’ekifuulannenge.

Omanya otya oba olina myotonia?

Bw’oba ​​otandika enkola y’okuzuula, omusawo wo ajja kukubuuza ku bubonero bwo n’ebyafaayo by’obulamu bw’amaka go . Oluvannyuma, nga tebannaba kuwa magezi ku kukebera myotonia, bajja kugaana embeera endala ezitera okubeerawo eziyinza okuba nga ze zikuleetera obubonero, gamba ng’obulwadde bwa hypothyroidism .

Bino bye bigezo ebikozesebwa okuzuula obulwadde bwa myotonia:

• Creatine Kinase (CK) Okukebera omusaayi: Creatine kinase ye enzyme esangibwa okusinga mu binywa. Emiwendo gya CK gitera okulinnya mu myotonia.
• Electromyography (EMG): Okukebera kuno kwekenneenya obulamu n’enkola y’ebinywa byo eby’amagumba n’obusimu obubifuga.
• Okukebera obuzaale: Okukebera kuno kusobola okuzuula enkyukakyuka mu buzaale ezireeta ebika by’obuzaale eby’enjawulo.
• Okukebera omusaayi gwa potassium: Omusawo ayinza okukozesa okukebera kuno okukebera oba obulwadde bwa hyperkalemic periodic paralysis (potassium mungi mu musaayi) oba hypokalemic periodic paralysis (potassium mu musaayi).
• Okugezesa dduyiro mu bumpimpi: Mu kukebera kuno, olina okukonziba ebinywa byo mu bbanga erigere ng’omusawo yeetegereza engeri obusimu n’ebinywa byo gye biddamu.

Myotonia bulwadde obutatera kulabika, .Kiyinza okukutwalira ekiseera okusobola okuzuula ekituufu. Ekyo tokyeraliikirira.

Bujjanjabi ki obuweebwa obulwadde bwa myotonia?

Obujjanjabi bw’obulwadde bwa myotonia bukwata ku kika kyo n’obubonero bwo. Ggwe n’omusawo mujja kukolera wamu okukola enteekateeka y’obujjanjabi etuukana n’ebyetaago byo. Tolonzalonza kubuuza kibuuzo kyonna ky’oyinza okuba nakyo.

Obujjanjabi bw’omubiri butera okuba ekitundu ku nteekateeka yo ey’obujjanjabi. Omusawo w’omubiri asobola okukuyamba okwewala ebimanyiddwa oba ebiyinza okukuleetera okukola dduyiro n’okukola enteekateeka y’okukola dduyiro ekuyamba okusigala ng’okola nga bwe kisoboka. Abasawo abajjanjaba emirimu nabo basobola okukuyamba okufuna engeri empya gy’oyinza okukolamu emirimu egya bulijjo. Era bayinza okukuwa amagezi ku bintu ebiyamba omuntu okukyusakyusa mu mbeera oba okutambula.

Obujjanjabi bwa Dystrophic Myotonia

Dystrophic Myotonia ejjanjabwa mu bubonero. Ojja kwetaaga okwekebejjebwa buli kiseera okulondoola obulamu bw’ebitundu ebikoseddwa ekika kyo ekya Dystrophic Myotonia.

Eddagala abasawo lye basinga okuwandiika ye mexiletine . It is actually an antiarrhythmic medication , naye era eyamba ku kunyiga ebinywa n’okukaluba. Mexiletine era eyinza okuyamba ku bika ebimu eby’obulwadde bwa myotonia obutali bwa dystrophic.

Obujjanjabi bwa Myotonia obutali bwa dystrophic

Ng’oggyeeko eddagala, obujjanjabi bw’obulwadde bwa myotonia obutali bwa dystrophic buyinza okuzingiramu okwewala ebintu ebimu ebivaako obulwadde buno. Mu bino mulimu:

• Okwewala okubeera mu mbeera ennyogovu.
• Okussa ekkomo ku dduyiro ow’amaanyi era ow’amaanyi.

Obujjanjabi bw’okusannyalala buli luvannyuma lwa kiseera

Obujjanjabi bw’okusannyalala buli luvannyuma lwa kiseera butera okuzingiramu okufuga omuwendo gwa potassium n’okwewala ebivaako. Omusawo ayinza okukuwa amagezi okwewala ebintu bino:

• Okuwummula okumala ebbanga eddene ng’omaze okukola dduyiro.
• Okulya emmere erimu ebirungo ebizimba omubiri ebingi.
• Okulya mu biseera ebitali bya bulijjo.
• Otulo obutali bwa bulijjo.
• Okukola ekiro.

Bw’oba ​​olina obulwadde bwa hypokalemic periodic paralysis , omusawo ayinza okukuwa amagezi okulya emmere erimu ekirungo kya potassium, gamba ng’ebijanjaalo, ebinyeebwa, ebibala ebikalu, emiyembe, n’amapaapaali.

Bw'oba olina obulwadde bwa hyperkalemic periodic paralysis , kiyinza okwetaaga okwewala emmere erimu ekirungo kya potassium ekingi .

Singa ebikolwa bino tebimala kufuga bubonero bwo, omusawo ayinza okukuwa eddagala erimu ku ddagala eriyitibwa dichlorphenamide oba acetazolamide .

Okukula kw’obulwadde bwa myotonia kuyinza okuziyizibwa?

Myotonia eva ku nkyukakyuka mu buzaale, n’olwekyo tewali ky’oyinza kukola kugiziyiza. Singa omuntu mu maka go alina obulwadde bwa myotonia, oba ggwe kennyini olina obulwadde buno, era ng’oteekateeka okuzaala, lowooza ku ky’okulaba omuwabuzi ku by’obuzaale . Basobola okunnyonnyola akabi k’olina okusikira embeera eno n’okugiyisa mu mulembe gwo oguddako.

Prognosis ki eri omuntu alina myotonia? (Okuteebereza)

Bw’oba ​​olina myotonia, endowooza yo esinziira ku bintu ebiwerako. Mu bino mulimu:

• Ekika kya myotonia ky’olina.
• Obuzibu bw’obubonero bwo.
• Engeri omubiri gwo gye gukwatamu obujjanjabi.
• Obulamu bwo okutwalira awamu n’emyaka gyo.

Omusawo wo ajja kusobola okukuwa endowooza ennungi ku biseera eby’omu maaso bye bigenda okubeera mu mbeera yo entongole, naye okutwalira awamu kintu nga kino:

• Okutwalira awamu myotonias ezitali za dystrophic zirina prognosis ennungi, naye kino kiyinza okwawukana okusinziira ku buzibu bw’obubonero bwo.
• Enteebereza y’obulwadde bwa dystrophic myotonias esinziira ku ngeri enkola z’omubiri endala gye zikosebwamu ennyo. Myotonic dystrophy types 1 ne 2 nazo zisobola okukendeeza ku bulamu bw’omuntu.
• Okusannyalala buli luvannyuma lwa kiseera kuyinza okweyongera n’emyaka, era era kuyinza okuvaako obuzibu bw’ebinywa obw’olubeerera, obw’amaanyi (myopathy) .

Ddi lwe nnina okulaba omusawo?

Myotonia mbeera etawona/ewangaala. Kale, ojja kwetaaga okulaba omusawo obulamu bwo bwonna okulondoola obubonero bwo n’okulaba engeri obujjanjabi bwo gye bukola obulungi.

Ekikulu, embeera ezikwatagana n’obulwadde bwa myotonia ziyinza okukosa engeri gy’okwatamu eddagala eribudamya . Bw’oba ​​olina okulongoosebwa kwonna, olina okubuulira omusawo wo. Era olina okutegeeza omusawo agenda okukulabirira ng’olongooseddwa.

Kya bulijjo okuwulira ng’olina ensisi era ng’oli wekka ng’ozuuliddwa ng’olina obulwadde obutatera kulabika. Myotonia ekosa buli muntu mu ngeri ya njawulo, n’olwekyo oyinza okuba n’ebibuuzo bingi. Ttiimu yo ey’abasawo ejja kuba naawe mu lugendo lwo lwonna olw’okuzuula n’okujjanjaba. Funa obuwagizi okuva gye bali, awamu n’abaagalwa bo.

Ebintu ebikulu bye twetaaga okujjukira (Take-Home Message) .

Myotonia mbeera ng’ebinywa tebiwummudde mangu oluvannyuma lw’okukonziba. Kino kiva ku nsonga z’obuzaale.

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- Kino kirina ebika bibiri ebikulu: dystrophic (okwonooneka ensengekera y’ebinywa) ne non-dystrophic (tewali kwonoona nsengekera).

- Obubonero buyinza okuli okukaluba kw’ebinywa, okunafuwa, okulumwa, n’okukoowa. Ebika ebimu nabyo biba n’obubonero obw’enjawulo.

- Okukebera omusaayi, EMG, n’okukebera obuzaale bye bikozesebwa okuzuula obulwadde buno.

- Obujjanjabi bwawukana okusinziira ku kika ky’obulwadde n’obubonero. Kuno kw’ogatta obujjanjabi bw’omubiri, eddagala, n’okwewala ebintu ebimu (ebivaako).

- Kino tekiyinza kuziyizibwa, naye osobola okufuna obuyambi okuva mu kubudaabudibwa ku buzaale.

- Bwoba olina obubonero buno, definitely laba omusawo. Enteekateeka entuufu ey’okuzuula obulwadde n’okujjanjaba kikulu nnyo gy’oli.

` Myotonia, Myotonia, Okukaluba kw’ebinywa, Endwadde z’obuzaale, Dystrophic Myotonia, Dystrophic Myotonia, Non-dystrophic Myotonia, Endwadde z’ebinywa