Olina ekizimba ku nseke yo eya pituitary? (Pituitary Adenoma) Ka tuyige ku nsonga eno!

Era oluusi ofuna omutwe ogukuluma awatali nsonga? Oba owulira ng’amaaso go ganafuye katono, ate nga tosobola kulaba bulungi bintu biva ku mabbali? Oba, olina obuzibu bwonna obuva ku nkyukakyuka ezimu mu busimu bw’omubiri gwo? Mpozzi ensonga lwaki ebintu bino ye kizimba ekitono ekikula mu nseke yo ey’omu lubuto. Leero, tugenda kwogera mu bujjuvu ku mbeera eno eyitibwa `Pituitary Adenoma` . Tofaayo, ono si kookolo.

Obulwadde bwa pituitary adenoma kye ki?

Mu ngeri ennyangu, pituitary adenoma kizimba ekitali kya kookolo (benign) ekikula mu pituitary gland yo. Tebusaasaana mu bitundu by’omubiri ebirala nga kookolo. Ekyo kye kintu ekisinga obukulu. Wabula adenoma eno bw’egenda ekula, esobola okunyigiriza ebintu ng’obusimu n’emisuwa egigyetoolodde. Awo obubonero we butandikira okulabika.

Kale, endwadde eno ey’omubiri (pituitary gland) kye ki?

Teebereza, emabega w’ennyindo yaffe, nga tuyungiddwa ku musingi gw’obwongo, ``Hypothalamus``, waliwo akatundu akatono akalinga entangawuuzi. Ekyo kye kiyitibwa enseke y’omubiri (pituitary gland). Wadde nga ntono, ekola omulimu omukulu ennyo mu mubiri gwaffe. Endwadde eno erina ebitundu bibiri ebikulu:

• Ekitundu eky’omu maaso
• Ekitundu eky’emabega

Ebitundu bino byombi bikola era ne bifulumya ebika by’obusimu eby’enjawulo mu musaayi. Obusimu bulinga ababaka ba kemiko abafuga era ne bakwasaganya emirimu egy’enjawulo mu mubiri gwaffe. Zitambula mu musaayi ne zituusa obubaka obwetaagisa mu bitundu byaffe, ebinywa n’ebitundu ebirala. Bino bye bimu ku busimu obukulu obukolebwa enseke z’omubiri (pituitary gland):

• Obusimu obuyitibwa adrenocorticotropic hormone (ACTH oba Corticotropin) .
• Obusimu obuziyiza omusulo (ADH oba Vasopressin) .
• Obusimu obusitula enseke (` FSH` ) .
• Obusimu obukula (`GH`) .
• Obusimu obukola omubiri (`LH`) .
• Okisitosini (` Okisitosiini` ) .
• Ekirungo kya Prolactin
• Obusimu obusitula thyroid (`TSH`) .

Tekikoma ku kino, enseke z'omubiri (pituitary gland) nazo "ekola akabonero" ku nseke endala ez'omubiri (endocrine glands) mu mubiri gwaffe okukola obusimu. Kale osobola okukitegeera nti singa wabaawo ekizibu ku nseke eno ey’omu lubuto, gamba nga adenoma, enkola y’obusimu emu oba obusimu obuwerako eyinza okukosebwa.

Ebika bya adenomas bino byawulwa bitya?

Abasawo bagabanya ebitundu by’omubiri ebiyitibwa pituitary adenomas mu bika bibiri ebikulu: 1. Okusinziira ku oba bikola obusimu oba nedda:

• Okukola/Okufulumya adenoma:Okugatta ku ekyo, ebika bya adenomas bino bikola obusimu bumu oba ebisingawo mu pituitary . N’olwekyo, obubonero n’embeera ez’enjawulo bisobola okubaawo okusinziira ku busimu obusukkiridde.
• Adenomas ezitakola/Ezitafulumya: Adenomas zino tezikola hormones. Kyokka singa zikula nga zinene, zisobola okuleeta obubonero nga zinyiga ebitundu by’obwongo oba obusimu obuli okumpi . Kino kye kika ky’obulwadde bwa adenoma abasawo bwe basinga okusanga.

2. Okusinziira ku sayizi:

• Microadenomas: Bino bizimba bitono okusinga milimita 10 (kwe kugamba, sentimita emu).
• Macroadenomas: Bino bizimba ebinene okusinga milimita 10. Macroadenomas zisinga emirundi nga ebiri okusinga microadenomas. Era zitera okuleeta obusimu obumu oba ebisingawo mu pituitary (embeera eyitibwa hypopituitarism).

Kino kitwalibwa ng’ekizimba ku bwongo?

Ensigo ya pituitary mu butuufu nsengekera ebeera mu nkola ya endocrine, era mu by’ekikugu si kitundu kya bwongo. Kikwatagana ku musingi gw’obwongo. Kyokka, abasawo batwala obulwadde bwa pituitary adenomas ng’ekika ky’ekizimba ku bwongo . Pituitary adenomas zikola ebitundu 10% byokka ku bizimba by’obwongo ebisookerwako.

Ani asinga okufuna bino? Kitera kitya?

Pituitary adenomas zisobola okukula ku myaka gyonna. Kyokka, zisinga kubeera mu bantu abali mu myaka 30 ne 40 . Abakyala nabo batera okuzifuna okusinga abasajja. Zitera nnyo ne kiba nti zikola ebitundu 10% ku 15% ku bizimba byonna ebikula munda mu kiwanga. Okusinziira ku bibalo, abantu nga 77 ku 100,000 balina embeera eno. Wabula abanoonyereza balowooza nti abantu abalala bangi, mpozzi nga 20%, bajja kufuna emu mu kiseera ekimu mu bulamu bwabwe. Emirundi mingi naddala abo abalina microadenomas (`microadenomas`), tebalina bubonero bwonna, kale tebazuulibwa.

Bubonero ki obulaga obulwadde bwa pituitary adenoma?

Obubonero bw’obulwadde bwa pituitary adenoma busobola okwawukana nnyo okusinziira ku muntu. Okusinga kisinziira ku bintu ebiwerako:

• Oba adenoma ekula mu bunene n’eyonoona enseke yennyini, oba ereeta ``mass effect'' ku nsengekera ezigyetoolodde.
• Ddala adenoma efulumya obusimu (`ekola`)? Bwe kiba bwe kityo, obubonero bujja kusinziira ku kika ky’obusimu bw’akola.

Obubonero bwa `Mass Effect` obuva ku `Macroadenomas` (ebizimba ebinene) .

Adenomas ennene (`Macroadenomas`) zireeta obubonero okusinga olw’okunyigirizibwa ku bitundu ebibyetoolodde.

Lowooza, bw’oteeka ekintu ekinene mu kasenge akatono, kiringa ekifo ekitali kimala ku bintu birala ate nga kijjudde abantu.

• Obuzibu mu kulaba:

Abantu nga 40% ku 60% abalina obulwadde bwa pituitary adenoma obuneneOkufiirwa okulaba (okulaba okuzibu, okulaba emirundi ebiri) kubaawo. Kino kibaawo kubanga adenoma enyigiriza ku optic chiasm, egatta amaaso n’obwongo. Kino kiyinza okuvaako okubulwa okulaba okw’okumpi naddala mu bbali. Kiringa embalaasi okubulwa okulaba kwayo ku njuyi zombi.

• Obulumi bw'omutwe :

Abantu bangi abalina obulwadde bwa pituitary adenomas beemulugunya olw’okulumwa omutwe emirundi mingi. Kino kiyinza okuba nga kiva ku kizimba okunyiga ku bitundu ebikyetoolodde. Kyokka olw’okuba obulumi bw’omutwe butera kuva ku bintu bingi, era buyinza okuva ku bintu ebirala.

• Obutaba na Busimu:

Adenomas ennene (`Macroadenomas`) zisobola okwonoona ebitundu by’endwadde z’omu lubuto (pituitary gland tissue) ne zikendeeza ku kukola obusimu obumu oba ebisingawo. Embeera eno eyitibwa `Hypopituitarism`. Obubonero obubaawo nga buli busimu bukendedde nabwo bwawukana.

• Obusimu bwa LH ne FSH bwe bukendeera (`Hypogonadism`): Emiwendo gya ` Oestrogen` mu bakyala ne ` Testosterone` mu basajja gikendeera. Kino kiyinza okuvaako obubonero ng’okutuuyana ennyo , okukala kw’obukyala mu bakyala, ` Erectile Dysfunction` mu basajja, okukendeera kw’enviiri mu maaso n’omubiri, okukyuka kw’embeera mu basajja bombi, okukendeeza obwagazi, n’okukoowa ennyo.
• Obusimu bwa TSH bwe bukendeera (`Hypothyroidism`): Omuwendo gw’obusimu obukolebwa endwadde y’ekibumba gukendeera. Kino kiyinza okuvaako obubonero ng’obukoowu, okuziyira, omutima okukuba empola, olususu okukala, okuzimba ebitundu by’omubiri, n’obutakola bulungi mu kukola emirimu gy’omubiri.
• Obusimu bwa ACTH bwe buba butono (`Adrenal Insufficiency`): Omubiri okukola obusimu bwa `Cortisol` bukendeera. Kino kiyinza okuvaako obubonero nga puleesa okukka, okuziyira, okusesema, okulumwa olubuto, n’obutayagala mmere.
• GH (Growth Hormone Deficiency): Obubonero bwawukana okusinziira ku myaka. Abantu abakulu bayinza okukoowa n’okufiirwa ebinywa.

Obubonero bwa adenomas ezikola

Ng’oggyeeko okufulumya obusimu bumu oba okusingawo, adenoma ekola esobola okuleeta obubonero n’embeera ez’enjawulo ezikwatagana ne buli busimu.

• Prolactinomas (era ezimanyiddwa nga Lactotroph Adenomas):

Adenomas zino zikola ekisusse ku hormone prolactin . Embeera eno eyitibwa hyperprolactinemia. Ebizimba by’omubiri ebiyitibwa pituitary tumors nga 4 byokka ku 10 bye bya kika kino. Kino kye kika ky’obulwadde bwa pituitary adenoma obusinga okubeerawo.Omuwendo gwa prolactin bwe gweyongera, enkola eya bulijjo ey’enkola y’okuzaala mu bakyala n’abasajja eyinza okutaataaganyizibwa.

• Obutazaala (obutazaala) eri abasajja n’abakazi.
• Amazzi agafuluma mu mabeere ne bwe gaba tolina lubuto (`Galactorrhea`).

• Ebizimba ebiyitibwa Somatotroph Adenomas:

Adenomas zino zikola obungi obuyitiridde obw’obusimu obukula (`Growth Hormone` oba `Somatotropin`) . Ebizimba bya pituitary nga 2 ku 10 bya kika kino. Obubonero obuva ku kino bwawukana okusinziira ku myaka.

• Abantu abakulu: Embeera etali ya bulijjo naye nga ya maanyi eyitibwa `Acromegaly` ebaawo. Mu kino, amagumba n’ebitundu by’omubiri bikula mu ngeri etaali ya bulijjo. Ekiseera bwe kigenda kiyitawo, emikono, ebigere n’omutwe byeyongera obunene, era enkula ya ffeesi n’ekyuka. Era kikosa okufuga ssukaali mu musaayi, era n’ebinywa by’omutima bisobola okugaziwa.
• Abaana n’abavubuka abakulu: Embeera eyitibwa gigantism ebaawo. Zikula nga ziwanvu mu ngeri etaali ya bulijjo olw’obusimu bw’okukula obuyitiridde.

• Ebizimba ebiyitibwa Corticotroph Adenomas:

Adenomas zino zikola ACTH (adrenocorticotropic hormone) mungi nnyo . Ebizimba bya pituitary nga 1 ku buli 10 bya kika kino. Obusimu bwa ACTH busitula endwadde z’ekibumba okukola obusimu obusingawo obuyitibwa steroid nga cortisol. Kino kireeta obulwadde bwa Cushing’s Syndrome (ekirungo kya cortisol ekisukkiridde).

• Puleesa eri waggulu.
• Obunafu bw’ebinywa.
• Okunyiga ebiwundu ebyangu.
• Emisono egya kakobe emigazi (okusukka sentimita emu) (`Stretch Marks`) girabika ku lubuto.
• Obulwadde bw’amagumba.
• Okumenya okunyigirizibwa.
• Obulwadde bwa sukaali obw’ekika eky’okubiri.

• Ensigo z’omubiri eziyitibwa thyrotroph Adenomas:

Adenomas zino zikola TSH (obusimu obusitula thyroid) obuyitiridde . Bino biba bitono nnyo. TSH esitula endwadde z’ekibumba okukola obusimu bwa thyroid obusingawo. Kino kireeta `Hyperthyroidism` (embeera ya thyroid ekola ennyo), eyanguya enkyukakyuka mu mubiri.

• Omutima gweyongera okukuba.
• Okugejja awatali nsonga yonna.
• Omusulo ogutera okutambula.
• Okutuuyana.
• Okukankana kw’emikono.
• Okweraliikirira.

Ekikulu: Waliwo ebintu ebirala bingi ebivaako obulwadde bwa hyperthyroidism. Obulwadde bwa pituitary adenoma butera nnyo okuvaako.

• Ebizimba ebiyitibwa Gonadotroph Adenomas:

Adenomas zino zikola obungi obuyitiridde obwa gonadotropins (i.e., obusimu LH ne FSH). Kino nakyo tekitera kubaawo nnyo.

• Kino kiyinza okuvaako abakyala okufuna enzirukanya y’ensonga ezitali za bulijjo n’embeera nga Ovarian Hyperstimulation Syndrome (OHSS).
• Abasajja bayinza okufuna obubonero ng’ensigo okugaziwa, eddoboozi okuzimba, enviiri okugwa (emabega w’amatu), n’enviiri mu maaso okukula amangu.
• Abaana nabo basobola okutuuka mu myaka gy’obuvubuka nga tebunnatuuka.

Biki ebivaako obulwadde bwa pituitary adenoma?

Bannasayansi n’okutuusa kati tebamanyi kituufu kivaako adenomas zino. Wabula, adenomas ezimu zilowoozebwa okuba nga zikwatagana n’enkyukakyuka ezitali za bulijjo (`mutations`) mu buzaale (`DNA`) mu butoffaali bwaffe. Enkyukakyuka zino ez’obuzaale zireetera obutoffaali obuli mu nseke z’omubiri (pituitary gland) okukula amangu ne bukola ekibinja. Enkyukakyuka zino mu buzaale oluusi zisobola okusikira abazadde okutuuka ku baana (ez’obusika), oba ziyinza okukula mu ngeri ey’ekifuulannenge ddala. Okugatta ku ekyo, ebitundu by’omubiri ebiyitibwa pituitary adenomas nabyo bisobola okukwatagana n’embeera ezimu ez’obuzaale ezitatera kubaawo . Ebimu ku byokulabirako bye bino:

• ``Obulwadde bwa Endocrine Neoplasia obw'ekika kya 1 (MEN1)''.
• ``Obulwadde bwa Endocrine Neoplasia obw'ekika kya 4 (MEN4)''.
• `Ekizimbe kya Carney`
• `Obulwadde bwa X-LAG`
• ``Obulwadde bwa succinate dehydrogenase obukwatagana n'obulwadde bwa pituitary adenoma obw'amaka''.
• `Obulwadde bw'obusimu obuyitibwa neurofibromatosis ekika kya 1`
• ``Obulwadde bwa Von Hippel–Lindau''.

Omuntu alina embeera eno ey’obuzaale aba mu bulabe obw’okufuna obulwadde bwa pituitary adenoma. Wabula kikulu okujjukira nti abantu abatalina mbeera yonna ey’obuzaale ng’eyo nabo basobola okufuna adenomas zino.

Abasawo bazuula batya embeera eno?

Enkola y’okuzuula obulwadde bwa pituitary adenoma ekyukakyuka okusinziira ku kika kya adenoma gy’olina n’okumanya oba y’ereeta obubonero. Ebiseera ebisinga, omuntu alina obulwadde bwa adenoma obufulumya obusimu (`Functioning Adenoma`) asooka kuzuulibwa nti alina obutakwatagana mu busimu (e.g. `Cushing's Syndrome`, `Acromegaly`) okusinziira ku bubonero. Olwo lwokka adenoma w’ezuulibwa ng’enoonyerezebwako ekivaako. Kino kiri bwe kityo kubanga embeera nnyingi ezireetebwa obusimu obuyitiridde ziyinza okuba n’ensonga endala ng’oggyeeko obulwadde bwa pituitary adenomas. Ekintu kye kimu kiyinza okwogerwa ku bbula ly’obusimu bw’omubiri (`Hypopituitarism`). Oluusi, obulwadde bwa pituitary adenoma buzuulibwa nga `Incidental Finding` mu kiseera ky’okukebera omutwe (`Imaging Test`) ku mbeera endala. Adenomas ezisinga ezisangibwa bwe ziti zitera okuba entono mu sayizi ate nga tezikola.

Kino kigezo ki ekikolebwa?

Singa omusawo wo ateebereza nti oyinza okuba n’obulwadde bwa pituitary adenoma, ajja kutunuulira n’obwegendereza obubonero bwo, ebyafaayo byo eby’obujjanjabi, n’okukeberebwa omubiri gwo. Okugatta ku ekyo, bayinza okuteesa ku kukebera ekimu oba ebisingawo ku bino wammanga:

• Okukebera Omusaayi: Okusinziira ku bubonero bwo, oyinza okulagirwa okukeberebwa omusaayi okukebera emiwendo gy’obusimu obw’enjawulo obuyitibwa pituitary hormones.
• Okukebera ebifaananyi: Okukebera omutwe mu MRI (Magnetic Resonance Imaging) obaSikaani ya `CT (Computed Tomography)` esobola okufulumya ebifaananyi ebitegeerekeka obulungi eby’ebizimbe ebiri munda mu mutwe. Ebigezo bino bisobola okukakasa oba waliwo obulwadde bwa pituitary adenoma n’obunene bwe buba. Okukebera kwa `MRI` kwe kugezesebwa okusinga okutuukirawo era okukwata ku kino.
• Okukebera amaaso: Bw’oba ​​olina obuzibu bwonna mu kulaba, omusawo ayinza okulagira okukeberebwa amaaso. Okukebera kuno kukulu kubanga ebitundu ebinene ebiyitibwa pituitary adenomas bisobola okuleeta obuzibu mu kulaba nga binyigiriza obusimu bw’amaaso obuyunga amaaso ku bwongo.

Obulwadde bwa pituitary adenoma bujjanjabwa butya?

Waliwo engeri ssatu enkulu ez’okujjanjaba obulwadde bwa pituitary adenomas: okulongoosa, eddagala, n’obujjanjabi obw’amasannyalaze. Oluusi enkola emu oba eziwera ku zino ziyinza okukozesebwa awamu. Olw’okuba buli muntu adenoma n’embeera ye bya njawulo, ggwe ne ttiimu yo ey’abasawo musobola okukolera awamu okuzuula enteekateeka y’obujjanjabi ekusinga.

Okulongoosebwa okuggyawo obulwadde bwa adenoma

Bw’oba ​​olina obulwadde bwa adenoma obuleeta obutakwatagana mu busimu oba obukosa okulaba kwo, omusawo ajja kukuwa amagezi okulongoosebwa okuggyamu adenoma yonna oba ekitundu. Okusinziira ku bunene bwa adenoma n’obuzibu bw’obubonero bwo, kiyinza okwetaagisa okulongoosebwa okusukka mu gumu. Abasawo abalongoosa batera okukola enkola eno nga bakozesa enkola y’okulongoosa eyitibwa `Transsphenoidal Surgery` . Kino kizingiramu okuyita mu nnyindo n’okuyita mu sphenoid sinus (ekifo ekirimu ekituli emabega w’ennyindo, wansi w’obwongo) okutuuka ku nnywanto ya pituitary n’okuggyawo adenoma. Ebitundu nga 95% ku bizimba by’omu lubuto (pituitary tumors) biggyibwawo mu ngeri eno. Enkola eno etali ya bulabe nnyo. Kyokka singa adenoma eba nnene nnyo nga tesobola kuggyibwa mu nnyindo oba ng’eri mu kifo ekizibu, omusawo ayinza okulongoosa omutwe. Eno nkola ya rare ku pituitary adenomas.

Obujjanjabi n’eddagala

Ebika ebimu ebya pituitary adenomas naddala prolactinomas , bisobola okufugibwa ne bikendeezebwa n’eddagala. Abantu abalina obulwadde bwa prolactinomas (bino bye bika ebisinga okubeerawo) basooka kujjanjabwa n’eddagala eriziyiza dopamine, nga Cabergoline (Dostinex®) oba Bromocriptine (Cycloset®), okumala emyezi egiwerako.

Amawulire amalungi gali nti mu bitundu nga 80%, eddagala lino likendeeza ku prolactinoma ne lizza obusimu bwa prolactin mu mbeera eya bulijjo.

Singa eddagala terikola oba bwe kiba kya kika kya adenoma eky’enjawulo, omusawo ayinza okukuwa amagezi okulongoosebwa.

Obujjanjabi bw’amasannyalaze (Radiation Therapy).

Obujjanjabi bw’amasannyalaze bukozesa X-rays ez’amaanyi amangi okusaanyaawo obutoffaali bwa adenoma, okukendeeza ekizimba oba okukikomya okukula. Stereotactic Radiosurgery ku bitundu by’omubiri ebiyitibwa Pituitary Adenomas(e.g. `Gamma Knife`®) Enkola ey’enjawulo, entuufu ennyo ey’obujjanjabi obw’amasannyalaze ekozesebwa. Mu kino, ebikondo by’obusannyalazo ebiwerako bigenderera adenoma okuva mu njuyi ez’enjawulo, ne bikendeeza ku kwonooneka kw’ebitundu ebiramu ebibyetoolodde. Enkola eno ekozesebwa ku bitundu ebisigaddewo oluvannyuma lw’okulongoosebwa oba mu mbeera ng’okulongoosebwa tekusoboka.

Biki ebiva mu bujjanjabi buno?

Nga bwe kiri ku bujjanjabi bwonna, obujjanjabi bw’obulwadde bwa pituitary adenoma buyinza okuba n’ebizibu ebimu.

• Oluvannyuma lw’okulongoosebwa ne/oba obujjanjabi obw’amasannyalaze, abantu nga 60% abalina obulwadde bwa pituitary adenomas bayinza okufuna `Hypopituitarism` (okukendeera kw’okukola obusimu bumu oba okusingawo obw’omu nseke). Wadde nga eno mbeera ya bulamu bwonna, eddagala erikyusa obusimu liyinza okuyamba abantu okubeera n’obulamu obwa bulijjo.
• Ebizibu ebiyinza okuva mu kulongoosebwa:
• Okuvaamu omusaayi.
• Cerebrospinal Fluid (CSF) leak (amazzi ag’amazzi agava mu nnyindo).
• Meningitis (obulwadde bw’obuwuka obubikka obwongo).
• Diabetes Insipidus (okufulumya omusulo ekisusse n’ennyonta esukkiridde olw’obutaba na busimu buziyiza okufulumya omusulo).
• Ebizibu ebitera okuva mu ddagala lya dopamine agonist eri prolactinoma mulimu: okulumwa omutwe, okuziyira, okusiiyibwa, okuziyira, n’oluusi okweyisa mu ngeri ewalirizibwa.
• Ebiyinza okuva mu bujjanjabi bw’amasannyalaze ag’amasannyalaze:
• Obutabeera na busimu bwa pituitary (kiyinza okubaawo okumala ekiseera).
• Okuzaala Okukosebwa.
• Okubulwa okulaba n’okwonooneka kw’ebitundu by’obwongo (tebitera nnyo).
• Ekizimba ekirala kiyinza okukula mu kifo kye kimu oluvannyuma lw’emyaka oluvannyuma lw’okujjanjabwa (tekitera kubaawo).

Okutondebwa kwa adenomas zino kuyinza okuziyizibwa?

Ebyembi tewali ky’oyinza kukola okuziyiza obulwadde bwa pituitary adenomas. Ebiseera ebisinga, bibaawo mu ngeri ya kimpowooze. Kyokka, ziyinza okuba nga zikwatagana n’ezimu ku mbeera z’obuzaale ezitatera kubaawo ezaayogeddwako emabegako. Singa omuntu ow’oku lusegere mu maka (ow’oluganda, mwannyinaze oba omuzadde) aba n’embeera y’obuzaale nga eno, osobola okwogera n’omusawo wo ku kubuulirira ku buzaale n’okukeberebwa okulaba oba naawe olina embeera eno. Bw’okola bw’otyo, omusawo asobola okukulondoola ennyo n’okuzuula n’okujjanjaba endwadde zonna ezikula nga bukyali.

Embeera eno etegeeza ki?

Endowooza y’obulwadde bwa pituitary adenoma, kwe kugamba, okuwona kwo n’obulamu bwo mu biseera eby’omu maaso, esinziira ku bunene n’ekika kya adenoma, n’obujjanjabi bw’ofuna .

Amawulire amalungi gali nti emirundi egisinga, adenoma bw’eggyibwawo ddala oba ng’efugibwa n’obujjanjabi, abalwadde basobola okuddamu okubeera n’obulamu obujjuvu, obulungi.

Mu mbeera ezimu, obujjanjabi busobola okukendeeza ku busimu obukola endwadde z’omubiri (pituitary gland). Kino bwe kibaawo, kiyinza okwetaagisa okumira eddagala erikyusa obusimu obulamu bwo bwonna okusobola okudda mu kifo ky’obusimu obukendedde. Adenomas oluusi zisobola okuddamu. Kino kitegeeza nti bayinza okwetaaga okuddamu okujjanjabibwa oluvannyuma lw’akaseera. Ebibalo biraga nti abantu nga 18% abalina adenomas ezitakola ate nga 25% ku bantu abalina prolactinoma bayinza okuddamu okwetaaga obujjanjabi mu biseera eby’omu maaso. N’olwekyo, kikulu nnyo okukwatagana n’omusawo buli kiseera n’okukeberebwa buli kiseera.

Kisoboka okubeera n’obulwadde bwa pituitary adenoma?

Yee, osobola. Singa ekizimba ky’omubiri ekiyitibwa pituitary adenoma kiba kitono era nga tekireeta bubonero bwonna, osobola okubeera nayo mu ngeri eya bulijjo. Mu butuufu abantu bangi bakizuula nti balina obulwadde bwa adenoma nga bakebereddwa omutwe olw’ensonga endala. Wabula singa adenoma yeeyongera okukula oba etandika okuleeta obubonero, mazima ddala ojja kwetaaga obujjanjabi. Bw’oba ​​olina obulwadde bwa pituitary adenoma obunene era/oba obukola (obukola obusimu), mazima ddala ojja kwetaaga obujjanjabi. Kino kiri bwe kityo kubanga ebizimba ebimu ebiyitibwa pituitary adenomas bisobola okukosa ennyo obulamu bwo n’omutindo gw’obulamu bwo.

Bizibu ki ebiyinza okubaawo singa tebijjanjabwa?

Singa tezijjanjabwa, ebizimba ebimu eby’omu lubuto – naddala ebizimba ebinene (`Macroadenomas`) n’ebizimba ebikola (`Secreting`) – bisobola okuleeta obuzibu obw’amaanyi mu bulamu . Ebizibu bino eby’obulamu bisinziira nnyo ku kika ky’obusimu obufulumizibwa adenoma (kino twakikyogerako emabegako mu kitundu kya `Symptoms`). Ekizibu ekitali kya bulijjo nnyo naye eky’akabi ennyo eky’obulwadde bwa pituitary adenomas obutajjanjabiddwa ye `Pituitary Apoplexy`. Eno `Medical Emergency`. Kino kibaawo nga waliwo omusaayi oguyingira oba okuva mu nseke y’omubiri (pituitary gland). `Pituitary Apoplexy` esinga kuva ku kuvaamu omusaayi mu pituitary adenoma. Ekizimba kikula mangu, ne kyonoona endwadde y’omubiri (pituitary gland). Adenoma gy’ekoma okuba ennene, n’obulabe bw’okulwala `Pituitary Apoplexy` gye bukoma okuba obunene. Obubonero bwa `Pituitary Apoplexy` butera okulabika mangu nnyo era buyinza okuteeka obulamu mu matigga . Obubonero obukulu bwe buno:

• Omutwe ogw’amaanyi ennyo (nga omutwe ogusinga obubi gwe nnali nfunye mu bulamu bwange).
• Okulaba emirundi ebiri oba obutasobola kusitula kikowe olw’ebinywa by’amaaso obutakola bulungi.
• Okubulwa okulaba ku mabbali oba okubulwa ddala okulaba mu liiso erimu oba gombi.
• Acute adrenal insufficiency ereeta puleesa okukka, okuziyira n’okusiiyibwa.
• Enkyukakyuka mu buntu (e.g., okutabulwa) olw’okufunda okw’amangu kw’omusuwa gw’obwongo ogw’omu maaso mu bwongo.

Obulwadde bwa pituitary apoplexy mbeera etali ya bulijjo, naye nga ya maanyi nnyo. Bw’ofuna obubonero bumu oba obusingawo ku buno, kuba ku ssimu y’abasawo ab’amangu (nga 911) mu bwangu oba omuntu akutwale mu kisenge ky’abalwadde ab’amangu eky’eddwaliro ekikuli okumpi.

Ddi lw’osaanidde okulaba omusawo?

• Bw’oba ​​olina obuzibu bwonna mu kulaba (okulaba okuzibu, okulaba emirundi ebiri, okukendeera kw’okulaba okw’okumpi) ne/oba okulumwa omutwe okutambula oba okuddirira (naddala mu kitundu ky’ekyenyi), laba omusawo obabuulire ku nsonga eno.
• Bw’oba ​​omaze okuzuulibwa nti olina obulwadde bwa pituitary adenoma, ojja kwetaaga okulaba omusawo buli kiseera okulondoola embeera y’ekizimba kino n’okukakasa nti obujjanjabi bukola bulungi.

N’ekisembayo, jjukira ebintu bino:

Kya bulijjo nnyo okuwulira ng’otya n’okweraliikirira ng’okizudde nti olina ekizimba. Wabula amawulire amalungi ku pituitary adenomas gali nti okusinga (okusukka 99%) si kookolo (benign) era emirundi egisinga, obujjanjabi busobola okuvaamu ebirungi ennyo. Jjukira nti omusawo wo ye munno mu kutuuka ku bulamu bwo obusinga obulungi. N’olwekyo, tolwawo kutegeeza musawo wo ku bubonero bwonna, obutabeera bulungi, oba ebibuuzo by’oyinza okuba nabyo ku bujjanjabi bwo. Bw’ofuna amawulire amatuufu n’obujjanjabi mu budde, mazima ddala osobola okuddukanya embeera eno obulungi.