I chau reng em? I vun chu a dum ta em? Addison natna chungchang hi i zir dawn teh ang!

I chau reng em, nunna nei loin i inhria em, i vun rawng pawh a danglam zauh zauh em? Salt duhna mak tak i nei mai thei. Chutiang symptoms chu a pangngai angin kan ngaihthah fo thin. Amaherawhchu, hengte hi kan taksa chhunga natna awm, chutiang khawpa awm lo, hriat chian a pawimawh em em a ni. Vawiin hian hetiang natna rapthlak tak hi kan sawi a, mahse uluk taka enkawl a nih chuan nun pangngaiin i nung thei a ni. Chu chu Addison-a Natna a ni .

A awlsam zawngin Addison-a Natna hi eng nge ni?

Okay, hei hi awlsam takin han sawifiah teh ang. Kan kal chungah hian gland te tak te, triangular ang maia lian, lukhum ang maia lian pahnih kan nei a. Hengte hi adrenal glands kan ti a . Hengte hi kan endocrine system-a thil pawimawh tak a ni.

Addison natna hi adrenal glands te hian hormone pawimawh pahnih, cortisol leh aldosterone te an siam chhuak tlem hle a ni.

Heng hormone pahnih hi eng atan nge kan mamawh?

• Cortisol: Hei hi nunna atana pawimawh tak hormone a ni. Kan taksa chu kan damloh lai te, accident kan tawh lai te, a nih loh leh operation kan neih lai te ang chi lungkhamna a tuar theih nan a pui a ni. Thisen sang, heart rate, immune system hnathawh, leh thisen glucose level te a tidanglam thei bawk.

• Aldosterone: He hormone hian kan taksaa minerals sodium (salt) leh potassium te balance turin a pui a. Kan kal (kidney) hian zun anga tui a chhuah zat pawh a control bawk. Hei hian kan thisen sang pawh direct-in a nghawng bawk.

Addison natna hi primary adrenal insufficiency tia hriat a ni bawk. A kaihhnawih natna dang a awm a, chu chu secondary adrenal insufficiency . Hetiang dinhmunah hian thluaka pituitary gland hian hormone ACTH , adrenal glands te chu cortisol siam turin a tichak tawk lo. Mahse vawiinah hian kan sawi ber chu adrenal glands ngeia buaina awm hi a ni.

Addison natna leh Cushing syndrome inthlauhna

Heng hming pahnih hi i buai phah mai thei. Heng pahnih hi dinhmun inthlau tak tak an ni.

He natna hi tuin nge vei tam ber? Engtiang chiahin nge a hluar?

Addison natna hian kum eng pawh a nghawng thei a, mahse kum 30 leh 50 inkar ah a tam ber .

Hei hi a takah chuan thil awm lo tak a ni . Entirnan, America ramah chuan he natna hian mi sang za zinga pakhat vel a vei a ni. Mahse kan ramah pawh hian he natna vei hi an awm ve tho.

He natna vei theihna chance sang zawk an awm. Chu chu autoimmune natna dang nei mi an ni . Chu chu kan taksa ngeiin kan taksa a venghimtu (immune system)-in kan cell-te a rawn beih natnate hi a ni. Chutiang natna kan neih chuan Addison natna vei theihna a sang zawk.

• Type I zunthlum vei a ni
• Thisen tlakchhamna (pernicious anemia) a awm
• Graves natna a ni
• Thyroiditis natna rei tak a awm
• Vitiligo - vunah a var a awm
• Myasthenia gravis natna (myasthenia gravis) a ni

Addison natna lan chhuah dan chu engte nge ni?

Addison natnaah hian adrenal glands chhiatna hi a thleng zauh zauh fo thin a, hun kal zelah a thleng thin. Chuvangin symptoms a lo lang zauh zauh thin. Heng symptoms te hi mi hrang hrangah a inang lo thei.

Hmeichhia pawhin thlasik hun mumal lo, taksa sam tlakchham, leh mipat hmeichhiatna lama duhna tlahniam te ang chi symptoms an nei thei bawk.

Addisonian crisis a lan chhuah dan:

• Tuar theih loh, chak lohna mak tak mai.
• Vawikhatmah, a hnungzang hnuai lam, pum chhung emaw, ke emaw a na hle.
• Rilru lama inthlak danglamna te, rilru hahdam lohna te, buaina te, hlauhna te.
• Luak chhuak nasa tak leh luak chhuak (hei hian tui tlakchhamna rang tak a thlen thei).
• Thisen sang tlahniam lutuk.
• Thil hriatna hloh.

Nangmah emaw, i hriat miin emaw heng symptoms te hi i neih chuan damdawi in hnai ber Emergency Department (ETU)-ah hruai nghal rawh.

Addison natna hi engte nge ni?

Addison natna thlentu ber leh awm tam ber chu autoimmune response a ni.. A awlsam zawngin kanmahni defense system (immune system) hian kan adrenal glands (adrenal cortex) pawn lam chu a rawn bei sual a, a tichhia a ni. Hetiang thil a thlen chhan dik tak hi hriat a la ni lo. Heng glands 90% vel an tihchhiat hnuah symptoms hi a lang tan thin. Hei hian thla tam tak a daih thei a, kum tam tak pawh a daih thei bawk.

Hei hi Addison-a damlo 75% awm chhan a ni.

A chhan dang hmuh tur awm lo:

• Tuberculosis: Tun hma chuan hei hi a thlentu lian tak a ni. Ram changkang zawkah chuan thil pawimawh tak a la ni reng a ni.
• Recurrent infections: HIV/AIDS leh fungal infection nena inzawm natna.
• Cancer: Hmun dang atanga cancer cell adrenal glands-a darh darh.
• Adrenal glands ah thisen chhuak.
• Adrenal glands te chu surgery hmanga lakchhuah a ni.
• Amyloidosis: Natna chi khat, taksa peng hrang hrangah protein chi khat a awm a, a tichhe thin.

He natna hi engtin nge kan hriat theih ang? (Diagnosis) tih a ni.

A lan chhuah dan hi a lo lang zawi hle a, natna dang tam takah pawh a awm fo avangin Addison natna hi a tir lamah chuan hriat a harsa thei hle. Vawi tam tak chu natna hi "incidentally"-in hmuhchhuah a ni. Doctor-te chuan natna dang nei leh awm loh thisen test pangngai an neih laiin thisenah sodium level hniam leh potassium level sang an hmuh chuan hei hi an ringhlel mai thei. Tin, vun hyperpigmentation hi he natna rinhlelhna thlentu symptom lian tak a ni bawk.

I natna lan chhuah dan a\anga i doctor-in a rinhlelh chuan natna hriat chian nan test eng emaw zat dang an ti leh ang.

Diagnostic test hrang hrang: 1.1.

• Thisen test: Thisen test hian sodium, potassium, cortisol, leh ACTH hormone awm zat a teh a. Addison natnaah chuan cortisol a hniam a, ACTH level a sang bawk.
• ACTH stimulation test: Hei hi a natna hriat chian nan test hman ber a ni. He test-ah hian synthetic ACTH hormone chu injection angin pek a ni a, darkar khat vel hnuah i thisena cortisol level chu teh a ni. I adrenal glands a hrisel chuan i cortisol level a sang tur a ni. Mahse, a tih loh chuan i adrenal glands te chu a thawk tha lo tih a nemnghet a ni.
• Insulin-induced hypoglycemia test: He test hi i natna lan chhuah dan hi pituitary gland-a harsatna avanga lo awm a nih leh nih loh hriat nan tih a ni.
• CT scan: CT scan hmangin i adrenal glands te chu a chhiat em, a infect em tih emaw, a lian lo deuh em tih enfiah theih a ni.

Engtin nge enkawl a nih?

Addison natna enkawl dan ber chu, .Hormone Replacement Therapy (HRT) hi taksaa hormone tlachhamte chu synthetic pill hmanga thlak danglam a ni.

• Hormone cortisol aiah damdawi hydrocortisone an tih chu pek a ni .
• Hormone aldosterone aiah damdawi fludrocortisone an tih chu pek a ni .

Heng damdawi ei zat hi mi hrang hrangah a inang lo. Tin, i doctor chuan Addisonian crisis i neih loh nan i dose chu rei lo te chhung atan a tipung thei bawk a, chu chu thil lungkhamthlak tak, infection, accident, emaw surgery emaw i tawn chuan a ni.

Fludrocortisone i ei a nih chuan i doctor chuan i ei leh inah chi tlem tal dah belh turin a fuih ang che, a bik takin khaw lum, thawmhnaw hah lai leh exercise nasa tak i tih hnuah.

Natna nena nung leh i tih tur

Enkawlna dik tak a neih chuan Addison natna vei chu nun pangngai tak, hrisel takin a nung thei a ni . Mahse, damdawi hman dan dik tak chu vawn reng a pawimawh hle.

Damdawi hi a tam lutuk chuan a thau lutuk, type 2 diabetes, osteoporosis, leh thisen sang te ang chi side effect a awm thei a ni. Chuvangin, i doctor (a tam zawkah chuan endocrinologist) hmu fo a, damdawi hman dan dik tak vawng reng turin a tul anga test neih a pawimawh hle.

Mahni himna atana i tih tur thilte:

• ID card emaw medical alert bracelet/necklace emaw ha fo ang che. Hei hian emergency-a i hriatna i hloh chuan medical staff-te chu Addison natna i vei tih an hriat theih nan a pui ang.
• Emergency a awm chuan cortisol shot i kutah dah reng tur chungchang i doctor nen sawiho rawh. Tin, chhungte emaw, i hmangaih tak emaw chu i hnena shot pek dan tur zirtir bawk ang che.
• I natna emaw, i rilru hahna nasa tak i neih emaw hunah i doctor hnenah eng nge i tih tur tih zawt rawh. Chutiang hunah chuan i damdawi ei tur zat chu tihdanglam a ngai mai thei.
• I doctor pan chhunzawm zel ang che.

Chronic condition i nei tih hriat hian rilru lamah a ti lungngai thei hle. Mahse thu lawmawm tak chu Addison natna hi damdawi hmangin a thunun tha hle a ni. A pawimawh ber chu doctor nena inbiak reng a, i mamawh enkawlna i hmuh hi a ni.