AL Amyloidosis hi eng nge ni? He natna rare tak hi thumal awlsam takin han sawi ila

Chau taka inhriat reng te, ke hrual te, thawk harsa tih te hi thil pangngai a ni tih i ngaihtuah ngai em? A châng chuan, heng symptoms hnung lamah hian kan hriat vak loh dinhmun buaithlak zawk a awm thei bawk. Vawiin hian chutiang natna hmuh tur awm lo pakhat, mahse i hriat chian tur chungchang kan sawi dawn a ni. Chu chu AL Amyloidosis a ni. He hming hi a hlauhawm deuhin a lang thei a, mahse awlsam tak leh chiang takin sawi ila.

A awlsam zawngin AL amyloidosis chu eng nge ni?

Kan taksaah factory te tak te kan nei a, chu chu plasma cell kan ti a ni tih han ngaihtuah teh. Chungte chu kan ruhroah a awm a. An hna ber chu kan taksaa hrik lutte do turin sipai antibodies an tih siam hi a ni. Hei hi kan taksa hriselna atana pawimawh tak a ni.

Mahse AL amyloidosis an tih condition ah chuan heng plasma cells ah hian defect te tak te a awm a. Hetiang chhiatna avang hian chu cell te chuan protein chi khat, a pianzia dik lo, a chhe tawh leh a pianzia dik lo tak chu an siam chhuak thin. Hei hi light chain protein an ti a .

Heng light chain proteins fold dik lo te hi an inzawm khawm a, tangles leh structure te tak te, fibrous structure te an siam thin. Chungte chu kan taksa peng hrang hrang, thinlung, kal, nerve, leh intestines-ah te a lo awm khawm a. Pipe bawlhhlawhin a tihkhawtlai ang bawkin heng protein te hi an lo awm khawm chuan chu taksa pengte chu an thawk tha thei lo. Hei hi AL amyloidosis kan tih chu a ni.

Engvangin nge hei hi AL an tih?

Amyloidosis hi chi hrang hrang a awm a. A chi tin hi a thlentu protein pangngai lo hming chawiin an vuah a ni. Letter A hi Amyloidosis tihna a ni a, L letter hi Light Chain tihna a ni.

He natna hian engtin nge taksa a nghawng?

Kan taksaah hian plasma cell chi hrang hrang sang tam tak a awm a. Type tin hian germ bik do turin antibody chi khat an siam a.

AL amyloidosis-ah chuan plasma cell pakhatah chhiatna a awm a, chu cell chu thunun theih lohvin a inthen a, cell chhia sang tam tak a siam chhuak a ni. Heng cell tin hian a hmaa kan sawi tawh ang khan light chain protein dik lo chu an siam chhuak vek a ni.

He protein tam tak hi kan thisenah a kal a, kan taksa peng hrang hrangah a awm tan ta a ni. Heng fiber deposit te hi amyloid fibrils an ti a . Chungte chuan taksa peng hrang hrangte chu a ti thim a, hna a thawk tha lo. Hun a kal zel a, hei hian chhiatna nasa tak a thlen thei a, nunna atana hlauhawm pawh a ni thei.

He natna hi tuin nge vei tam ber?

Hei hi a takah chuan natna hmuh tur awm lo tak a ni . Khawvel pumah mi tlemte a nghawng a, maktaduai khatah 5 leh 12 inkar a ni.

• Hmeichhia aiin mipa tan a tam zawkTendency to build up hi a tam lutuk deuh.
• Hetiang dinhmun hi kum 60 chunglam zingah a tam ber a, natna hmuhchhuah a nih lai hian kum zatve chu kum 64 vel a ni.

Eng symptoms nge hriat theih?

He natna chungchanga harsatna pakhat chu a lan chhuah dan hi natna tlanglawn dangte nen a inang fo thin hi a ni. Tin, heng symptoms te hi a lang zawi hle bawk. Chuvângin, a tîrah chuan danglamna tam tak i hmu lo mai thei. A hnuaia table-ah hian heng symptoms te hi eng nge ni tih i lo en ang u.

Engtin nge doctor hian he natna hi dik taka a hriat theih ang?

I natna lan chhuah dan a ngaihthlak hnuah doctor-in he natna hi a rinhlelh chuan test eng emaw zat a ti ang a, a finfiah ang.

Hei hi test pawimawh ber chu biopsy a ni . Hei hian a nghawng nia ngaih tissue emaw, taksa peng emaw te tak te tak tak lak a, microscope hmanga enfiah a huam a ni. Hei hian amyloid protein a awm leh awm loh chiang takin kan hmu thei a ni. Biopsy test hi a tlangpuiin:

• Bone marrow biopsy: Ruh chhunga ruhro atanga sample te tak te lak a ni.
• Kidney biopsy: Kidney atang hian tissue te tak te tak tak engemaw zat lak chhuah a ni.
• Heart biopsy: Heart muscle te te engemaw zat lak a ni.
• Abdominal fat pad biopsy: Pum vun hnuaia thau layer atanga tissue te tak te lak chhuah a ni.

Test dang pawh a awm bawk

Hei bakah hian i taksa peng hrang hrangte tihchhiat engzat nge tih hriat tumin test tam zawk neih a ni bawk.

• Thisen test: Hengte hian kal, thinlung leh thin hnathawh dan hriat theihna tur leh thisen chhunga light chain protein awm zat tehna atan a pui a ni.
• Zun test: Zun sample, a tlangpuiin darkar 24 chhunga lakkhawm chu kal (kidney)-ah chhiatna a awm em tih enfiah a ni.
• ECG (Electrocardiogram): Thinlung electric hnathawh dan tehna a ni.
• Echocardiogram: Thinlung ultrasound hmanga enfiah a ni. Hei hian thinlung chetna leh a lian leh te ang chi thil a en a.
• Cardiac MRI: He test hi thinlung thlalak chiang tak, chipchiar tak hmuh theihna tura tih a ni.

Hei hi eng enkawlna nge ni?

AL amyloidosis enkawlna kawngah hian thil tum lian tak tak engemaw zat a awm a. Pakhat chu symptoms control hi a ni. A dang chu organ damage enkawl a ni. Tin, a pawimawh ber chu, protein pangngai lo siam chhuah tihtawp nan .

Doctor-te chuan chemotherapy , immunotherapy , a nih loh leh steroid ang chi damdawi hmangin plasma cell chhia chu an tichhia a, chu chuan light chain protein thar siam chu a titawp ta a ni.

Thil engemaw takah chuan damlo dinhmun a zirin , ruhro emaw stem cell emaw thlak a rawt thei bawk. Heng zawng zawng hi i enkawltu doctor-in a rel vek a ni.

He natna hi eng chen nge i dam theih ang?

Hei hi mi tam tak tan chuan harsatna a ni. Dik tak chuan tunah chuan enkawlna thar hmangin AL amyloidosis vei te dam rei zawng chu nasa takin a tipung ta a ni. Mi thenkhat tan chuan natna khirh tak , damdawi hmanga tihreh theih a lo ni ta a ni.

Mahse hei hi natna khirh tak a ni tih hi kan theihnghilh tur a ni lo. Damlo hmalam hun tur chu thil tam takin a hril a, chu chu natna hriat chhuah a nih huna taksa peng hrang hrang a tihchhiat nasat dan te, taksain enkawlna a dawn dan te a ni.

He natna hi ven theih a ni em? Engtin nge ka in enkawl ang?

Vanduaithlak takin AL amyloidosis hi kan ven theih loh natna a ni lo. Plasma cell-a random mutation avanga lo awm a ni. Mahse natna hi hriat chian a nih veleh mahni inenkawlna tur thil engemaw zat a awm.

• Ei leh in tha: Enkawlna thenkhatah chuan ei duhna a tlahniam thei. Mahse i taksa chakna tur chuan ei leh in tha hi a pawimawh hle. I doctor nen i tana tha tur diet chungchang sawipui rawh.
• Chawlh hahdam tawk rawh: I taksa chu dam turin hun pe rawh. Mut tam la, chawlh hahdam rawh.
• Exercise tha tak: 1.1.Exercise hi rilru tan pawh a tha a, taksa tan pawh a tha. Mahse i doctor hnenah eng exercise nge him leh i taksa tana tha tih zawt rawh.
• Psychological support: Hetiang natna rare tak i neih hian midangte hriatthiam loh avangin mahni chauha awm leh inhlat takin i inhria thei. Chu chu thil pangngai a ni. Hetiang natna vei te tana support group chungchang hi i doctor zawt la. I thil tawnte midangte hnena sawi chhuah hi chakna ropui tak a ni.

AL amyloidosis hi natna khirh tak ni mahse, a hmaa hriatchhuah a, enkawlna dik tak dawng a, mahni in enkawl tha a, enkawl leh nunpui theih a ni.