Ankylosing Spondylitis, emaw AS i vei chuan hnungzang leh ruh natna leh ruh na tak tak tawn a harsat zia i hria ang. Tuna damdawi hman mek hmang hian mi tam takin hahdamna an hmuh laiin, mi zawng zawngin an ei thei vek lo. Mi thenkhat chuan side effect an nei thei bawk. Chuvang chuan scientist te chuan he natna enkawlna tha zawk zawn chhuah an tum reng a ni. Chutiang enkawlna beisei awm tak pakhat chu stem cell therapy emaw, kan hriat vek angin ‘Stem Cell Therapy’ emaw hi a ni. Vawiin hian thumal awlsam takin sawi ila.
Heng stem cell te hi engte nge ni?
A awlsam zawngin kan taksaa cell dang zawng zawng, thisen cell, muscle cell, leh vun cell te hi heng ‘mother cells’ stem cell an tih atang hian an lo piang hmasa ber a ni. Lehkhabu blank sheet angin ngaihtuah rawh. Heng cell te hian anmahni copy an siam thei a ni. Taksa mamawh cell chi hrang hrang an lo ni thei bawk. Entirnan, heng cell te hian taksa chhunga tissue leh organ chhia te siamthat theihna mak tak an nei a.
Chuvangin, he stem cell therapy-ah hian stem cell hrisel tak tak taksaah luhtir a ni a, taksa chu natna atanga a tihdam theih nan a pui a ni. Heng cell therapies hi chi hnih a awm a, chungte chu:
- Autologous: Enkawlna dawngtu hnen atanga cell lak chhuah te hman a ni.
- Allogenic: Mi hrisel dang (nu leh pa, unau, emaw, a kaihhnawih lo donor) atanga cell hmuh a hmang thin.
| Stem cells awmna hmunpui ber | Tuna enkawlna atana pawm tawh conditions |
|---|---|
| Tunah hian US-a FDA ang agency-te chuan natna tlemte chauh tan he enkawlna hi an pawm tawh a ni. A bulpui ber chu cancer leh thisen emaw immune system nena inzawm natna te an ni.
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He AS enkawlna hi a hlawk tak tak em?
Hetah hian kan fimkhur em em tur point a awm. Stem cell therapy hian nakin lawkah natna tam tak tihdam theihna tur thutiam nei mah se, Ankylosing Spondylitis (AS) enkawlna atan official-in pawm a la ni lo. Tin, arthritis leh chronic pain ang chi condition atan pawh pawm a la ni lo.
Chuvangin, AS damdawi kimchang tak advertise tu "clinic" emaw "medical center" emaw, dan anga kalpui lohte lakah fimkhur hle ang che. Enkawlna pawmpui loh avanga harsatna i tawk theihna chance a sang hle.
Mahse, beiseina hi kan thlahthlam vek tur a ni lo. Nakin lawkah chuan hei hi enkawlna pawmpui a nih theih a rinawm. Scientist te hian stem cell chi hrang hrang an la zirchiang mek a ni.
Mesenchymal stem cells (MSCs) te hi a awm a, a chhuak leh ta a.
Hengte hi cell chi khat bik an ni a, kan taksaa ruh, ruhro, thau leh thau ang chi thil siam that nan a pui thin. Tin, immune system tihreh nan leh taksaa inflammation control turin an pui bawk.
Scientist-te ngaihdan pakhat chu AS damlo atanga heng MSC-te hi thil dik lo a awm thei tih hi a ni. Chuvangin, mi hrisel atanga MSC inject hian AS hnuaia awm immune system imbalance chu a siam tha thei niin an ngai.
Zirna tenau tak tak tlemte chuan result beisei awm tak tak an hmuchhuak a:
- Zirchianna pakhatah chuan umbilical cord thisen atanga MSCs cells lakchhuah te chu AS vei panga hnenah pek a ni a, an natna leh an natna lanchhuahna te chu a tlahniam a ni.
- Zirna dang pakhatah chuan AS vei 31 te chu ruhro atanga chhuak MSCs cell pek an nih khan mi 10 zinga 7 chuan hahdamna engemaw chen an nei a ni. Mahse, heng result te hi hun rei lote chhung chauh kar 7 vel a ni.
- Mice hmanga zirchiannaah chuan MSCs hian inflammation thlentu cell te chu a thlak danglam thei tih hmuhchhuah a ni.
Mahse, hetah pawh hian, hengte hi zirchianna tenau tak tak an ni tih hre reng ang che. Zirna lian zawk result kan hmuh hma chuan thutlukna nghet tak kan siam thei lo.
He enkawlna hi engtiang chiahin nge a him?
Damdawi enkawlna eng pawh hi a thatna leh that lohna a awm a, mahse official-a pawmpui stem cell enkawlna chu mipui hnena pek a nih hmain test khauh tak tak neih a ni.
AS clinical trial-ah chuan MSC enkawlna hi a tlangpuiin a him tih hmuhchhuah a ni a, side effect na tak a awm lo. Mahse, he enkawlna hian mi zawng zawng tan hna a thawk lo. Mi thenkhat chuan an natna lan chhuah danah hmasawnna an nei lo a, mahse natna a zual zel tih erawh report a la awm lo.
He enkawlna hian side effect a neih tam ber chu infusion process avanga side effects awm thin te hi a ni.
- Enkawlna hnu rei vak lo awm thin khawsik.
- Needle dahna hmunah natna.
Cancer ang natna avanga stem cell therapy dawng thinte pawh chemotherapy emaw radiation emaw pek an ni thei a, hei hian thisen chhuah leh natna kai theihna a tipung thei a ni. Chuvangin, hei hi i doctor nen sawiho a pawimawh a, a hlauhawmna zawng zawng pawh chiang takin sawi rawh .
Cost leh Clinical Trial te a ni
He enkawlna hian dollar maktaduai tam tak a seng thei a ni. Tin, AS tan experimental treatment a la nih avangin i health insurance hian a cover lo mai thei bawk.
Hei atan hian duhthlan tur pakhat chu clinical trial zawm hi a ni . Hengte hi damdawi thar emaw, enkawlna thar emaw mipui hnena pek chhuah a nih hmaa a that leh him loh enfiahna zirchianna a ni.
Engtin nge clinical trial-ah hian kan tel theih ang?
I doctor hnenah i tana tha tur clinical trial chungchang i zawt thei ang. Hemi kawngah hian institution hmingthang tak takte hriatna a nei thei a ni.
Chutiang zirchiannaa i tel hmain, a ṭhatna leh ṭha lo zawng zawng ngun takin ngaihtuah hmasa phawt ang che. Hêng zawhnate hian chutianga ti tûrin a ṭanpui ang che:
- He zirchianna hian eng nge a tum ber?
- Ka tel ve theih nan eng nge ka tih ngai?
- Pawisa eng emaw zat ka hman a ngai dawn em ni?
- He zirchianna hi eng chen nge a daih ang?
- Hei hian tuna ka enkawlna dang a tibuai dawn em ni?
- Thil engemaw a kal dik loh chuan eng nge thleng?
Take-Home Thuchah a ni
- Ankylosing spondylitis (AS) hi natna khirh tak a ni. Tuna enkawlna hian symptoms a control thin.
- Stem cell therapy hi AS enkawlna beisei awm tak, mahse experimental tak a ni . Official-in a pawmpui enkawlna emaw, natna tihdamna emaw a la ni lo.
- Hmun pawm loh leh enkawlna, "AS hi a tidam vek" tih advertisement-ah fimkhur hle ang che.
- Enkawlna thar i ngaihtuah a nih chuan thutlukna i siam hmain i doctor nen inbia fo la , a thatna leh that lohna chiang takin hriattir hmasa phawt ang che.
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