Kan damloh hian, khawsik kan neih hian kan taksa chhungah indona lian tak a thleng thin tih i hria em? Kan taksa ngei pawh hian hrik, chu chu invader, pawn lam atanga hmuh theih loh khawpin a do thin. He defence force-a sipai bik leh thiam ber berte hi tunlaia kan sawi ‘antibody’ te hi an ni. Chûngte tel lo chuan khawsik tê tê pawh hian buaina nasa takah min luhtir thei a ni.
A awlsam zawngin, heng antibody te hi engte nge ni?
Hei hi hrethiam tur chuan entirnan tlem han la ila. I taksa hi ram venhimna tha tak a ni tih han ngaihtuah teh. He ram pawn atangin rukru leh hmelma an lo kal thei a ni. Chu chu bacteria, virus, fungi, leh toxins ang chi thil tihna a ni. Kan taksa tana chhiatna thlen thei leh pawn lam atanga lo chhuak eng pawh chu antigen kan ti thin . A awlsam zawngin antigen chu kan taksaa lut invader a ni.
Tunah chuan he invader (Antigen) hi taksaah a luh chuan kan defence system, immune system hian a hre chiang ta a ni. "Hetah hian mi hriat loh a lo kal!" Chutih lai tak chuan kan immune system hian he invader hi do turin protein chi khat bik antibody an tih chu a siam chhuak a. Chuvangin, antibody chu kan taksaa police emaw sipai emaw ang a ni.
Antibody sawina thumal dang chu Immunoglobulin tih hi a ni. I thisen test report thenkhatah chuan he hming hi (Ig) tia tawi zawngin i hmu mai thei.
Engtin nge heng antibody te hi an siam chhuah? Khawiah nge hna an thawh?
Kan taksaa thisen var chi khat B cells te hian heng antibodies siamtu factory angin hna an thawk a ni. Antigen, a nih loh leh hrik chu B cell nena a inzawm chuan B cell chu a inthen darh nghal vat a, a copy sâng tam tak a siam chhuak a ni. Heng cell tharte hi plasma cell kan ti a. Heng plasma cells te hian antibody maktaduai tam tak siamin thisen leh lymph system-ah an chhuah tir thin.
Chumi hnuah chuan heng antibody te hian taksa pum puiah an fang kual a, chu invader te chu an zawng chhuak a, an man a, an tichhia a ni.
Heng antibody te hi kan taksaah hmun tam takah hmuh tur a awm a:
- Thisenah chuan
- Vun
- Lung chhungah chuan
- Mittui nen
- Saliva ah chuan
- A bik takin nu hnute tuiah
Ni e, naute pian hnu ni engemaw zat chhunga nuin a chhuah chhuah hnute tui tak, colostrum an tih hian antibody a pai tam hle. Chuvang chuan nau hnute pek hian nasa takin naute invenna a tipung a ni. Naute hian nu taksa a\angin a venghimtu thilte chu direct-in a dawng a ni.
Antibody hi chi 5 a awm - an vai hian thil inang an ti vek lo!
Kan security force-ah hian regiment hrang hrang a awm ang bawkin antibodies hi chi hrang hrang 5-ah then a ni. Type tin hian chanvo bik an nei vek a. Eng nge an nih i en ang u.
| Antibody chi hrang hrang | Main function leh specialty a ni |
|---|---|
| Immunoglobulin G (IgG) a awm a, a chhuahna tur hmun leh a hmanna tur a awm lo. | Hei hi kan thisenah a tam ber chi a ni. Hengte hi an ni hian a hmaa hri kai tawhte hre rengin, chu natna hrik chu a lo let leh a nih chuan do turin an inpeih reng a ni. Heng IgG antibodies te hian nausen (placenta) te pawh an paltlang a, nausen pum chhunga naute chu an venghim bawk. |
| Immunoglobulin A (IgA) a awm a, a chhuahna tur hmun leh a hmanna tur a awm lo. | Hengte hi hnar, rilru, lung leh chaw ei kawng (digestive tract)-a mucous membrane-ah te hmuh tur a tam ber. Hei hian taksa chhunga hrik luhna kawngkhar an ni tihna a ni. Nu hnute tuiah pawh an tam hle. |
| Immunoglobulin M (IgM) a ni a, a man hi a to hle. | Hri kai tharin taksa a rawn deng chuan heng IgM sipaite hi indonaah an kal hmasa ber thin. Chuvangin tun hnaia hri kai a awm leh awm loh hriat nan IgM level an test thin. |
| Immunoglobulin E (IgE) hmanga enkawl a ni. | Hengte hi allergy lama thawktu ber an ni. IgE level hi taksain leivut, pollen leh ei tur thenkhat a tihbuai hian a sang chho zel a ni. Parasites te pawh an do bawk. |
| Immunoglobulin D (IgD) hmanga enkawl a ni. | Hengte hi thisenah hian a tlem hle a. B cells hnathawhna tura puitu nia ngaih ni mah se, an chanvo dik tak chu zirchian mek a ni. |
Lab-a antibody siam? Heng monoclonal antibodies te hi engte nge ni?
A chang chuan kan taksain a pianphung a siam chhuah antibody te hian natna a do thei lo mai thei. Chutiang hunah chuan scientist-te chuan laboratory-ah antibody chi khat bik an siam chhuak thin. Chungte chu Monoclonal Antibodies an ti a .
Chûngte chu a tumna hmuna missile thawn ang mai a ni. Heng antibodies te hi cell bik (e.g., cancer cell) emaw natna bik thlentu protein emaw chauh target leh attack tura siam an ni. Hetiang enkawlna hi immunotherapy an ti bawk .
Hetianga enkawl dan hi tunah chuan natna chi hrang hrang tan hman a ni ta.
| Monoclonal antibody therapy hmanna tur condition thenkhat |
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Hun bik thenkhat han sawi ila.
Antibodies chungchang kan sawi hian case bik tlemte kan hriat fo thin a awm.
COVID-19 leh antibody te a awm bawk
COVID-19 hripui leng nen chuan antibody chungchang kan hre tan ta vek a.
- COVID-19 atanga i dam leh tawh chuan i taksain hri do thei tur antibody a siam chhuak tawh tihna a ni.
- COVID-19 vaccine i lo dawng tawh a nih chuan i taksain antibody a siamchhuahna tur a tichak bawk ang.
- A pawimawh ber: COVID-19 atanga dam tawh miin vaccine a lak chuan chu mi chu antibody response a chak zawk hle. A venhimna a pek pawh a nasa zawk.
I taksaah COVID antibodies i nei em tih hriat nan antibody test i nei thei ang. Mahse, heng antibodies te hi taksaah eng chen nge an awm tih zirchianna chu kalpui mek a ni.
Thyroglobulin Antibodies (Thyroid gland beitu antibodies) 1. A rilru a hah lutuk chuan a rilru a buai em em a.
A châng chuan, kan taksa chakna (immune system) hian kan taksa peng hrisel tak takte chu a rawn bei sual ṭan ṭhin. Thyroid lama harsatna nei tam tak chuan anmahni thyroid gland beitu antibodies an nei a. Chungte chu Thyroglobulin antibodies an ti a .Hengte hian thyroid gland chu overactive (hyperthyroidism) emaw underactive (hypothyroidism) emaw a thlen thei a ni.
I doctor-in thyroid lama harsatna a rinhlelh chuan heng antibodies awm zat enfiah nan thisen test tir turin a ti thei a ni.
Autoantibodies a awm bawk
Hei hi a hmaa kan sawi tawh "self-attack" concept-a a bulpui ber a ni. Kan antibody te hian kan cell hrisel tak takah protein awmte chu "invader" tiin an ngai sual a, an bei tan thin. Heng antibodies te hi autoantibodies an ti a .
Hetiang dinhmun avanga natna lo awmte hi autoimmune diseases kan ti a ni .
- Lupus a ni
- Rheumatoid Arthritis natna a ni
- Hashimoto natna a ni
- Type 1 Diabetes a ni
Chutiang natna entirnan: ANA (Antinuclear Antibody) test hi chutiang natna rinhlelhna a awm huna test tih ber a ni.
ANA test a positive vang mai mai chuan autoimmune disease i nei tihna a ni lo. I doctor hian a chhui chian belh a ngai tihna chauh a ni. Chuvangin chutiang report chuan hlauthawng suh. Chumi chungchang chu i doctor nen sawiho rawh.
Take-Home Thuchah a ni
- Antibodies hi kan taksa immune system atanga protein siam, natna hrik, natna hrik leh toxins laka min vengtu a ni.
- Pawn lam atanga kan taksa tana chhiatna thlen thei thil chu antigen an ti a, chu chu do tumtu chu antibody an ti bawk.
- Nu hnute tui, a bik takin colostrum hian naute tan venhimna pawimawh tak a pe a, a chhan chu antibody a tam avangin.
- A chang chuan kan taksa peng hrisel tak takte hi keimahni antibody te hian a rawn bei thei thin. Hetiang dinhmun hi autoimmune diseases an ti a.
- Antibodies, immunity, emaw he thuziaka kan sawi tawh ang chi emaw chungchangah zawhna emaw, ngaihtuahna emaw i neih chuan i doctor nen sawiho rawh.
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