I taksa immune system, natna laka vengtu che defense system hian a chang chuan i cell hrisel tak takte chu a rawn bei sual tan thin. Hetiang dinhmun hi autoimmune disease an ti a. A tuar tawhte chauh hian a thlentu ruh na, a hring leh a nghet lo nen hian nun a harsatzia an hre chiang hle. Chuvangin, i doctor chuan DMARDs tih damdawi chi khat a pe che em? A nih loh leh an chanchin i hre tawh em? Vawiin hian heng DMARD te hi eng nge an nih, an hnathawh dan leh an chungchang i hriat tur te i sawi dawn nia.
DMARD te hi eng nge ni? A awlsam zawngin...
DMARD tih hi Disease-Modifying Antirheumatic Drugs tihna a ni. A hming hi a buaithlak deuh niin a lang a, a takah chuan hnathawh hi a awlsam khawp mai. Hengte hi damdawi bikte an ni a, i immune system chu a overactive lo va, i taksa ngei pawh a tichhe thei lo.
I immune system hi ram humhimtu sipai angin ngaihtuah rawh. A tlangpuiin he sipai hian ram dang hmelma (germs) chauh an bei thin. Mahse autoimmune disease-ah chuan he sipaite hi a kal bo a, mahni ram chhunga mi sual lo (taksa chhunga tissue hrisel) te chu an bei thin. DMARD-te tih thin chu he sipai chak lutuk hi tihlum a, a hnathawh dan tur dik tak siam leh hi a ni.
He damdawi atanga hlawkna i hmuh ber chu:
- Taksa a inflammation a tihziaawm a, chu chu a hring, a sen, leh a na tihna a ni.
- Natna a tiziaawm.
- Natna darh zel emaw, a nasat dan emaw a tikhawlo.
- Natna vanga i ruh leh ruhte chhiatna a tihtlem emaw, a veng emaw a ni.
- Joint function tha tak vawng reng turin a pui.
DMARD hi eng natna atan nge hman a nih?
Doctor-te chuan DMARD hi autoimmune condition hrang hrang, inflammation thlentu control nan an hmang ber a ni. Chûng zînga ṭhenkhat chu i hre tawh mai thei.
| Natna hming (Condition) . | Thuhmahruai tawi te |
|---|---|
| Rheumatoid Arthritis natna a ni | Thil awm dan tlangpui, ruh natna, hliam, leh ruh nghet lo. |
| Ankylosing Spondylitis natna a ni | Arthritis chi khat, ruhro a nghawng ber. |
| Psoriatic Arthritis natna a ni | Psoriasis hi arthritis chi khat a ni a, psoriasis vei thenkhatah a awm thin. |
| Lupus a ni | Natna, taksa peng hrang hrang vun, ruh, kal, leh thluak te a nghawng thei. |
| Juvenile Idiopathic Arthritis natna a ni | Naupang kum 16 hnuai lam ruh natna (arthritis) a awm. |
| Scleroderma a ni | Natna, a ziarang ber chu vun khauh leh thim a ni. |
| Multiple Sclerosis natna a ni | Nervous system natna, thluak leh ruhro (spinal cord) tichhe thei. |
Hei bakah hian DMARD hi cancer chi thenkhatah leh mit inflammatory condition uveitis tan pawh hman a ni tlem hle a, enkawlna dang a dawng lo bawk.
Eng chi DMARD nge awm?
DMARD hi chi hnihah then theih a ni.
1. Hmanlai DMARDs te
Hengte hi DMARD chi hrang hrang hmuhchhuah hmasak ber an ni. Heng damdawi te hian a tlangpuiin immune system zawng zawng a ti reh vek a ni . Side effect an neih tlem avangin i doctor hian he damdawi chi hi a rawn pe hmasa mai thei. Hengte hi pill angin an ei fo thin.
Entirna thenkhat:
- `Azathioprine` tih a ni
- `Hydroxychloroquine hmanga siam a ni`
- `Leflunomide` tih a ni
- `Methotrexate hmanga siam a ni`
- `Sulfasalazine` tih a ni
2. Biological DMARDs (Biologics) te hi a tha ber pawl a ni.
Hengte hi damdawi thar, changkang tak tak an ni. Sniper ang mai an ni. Traditional DMARDs angin immune system pumpui an nghawng lo a,Buaina thlentu immune cell bikte chauh an target a, an bei bawk.
Hengte hi a tlangpuiin DMARD hlui aiin a chak zawk a, a hlawk zawk bawk. Mahse, side effects risk tlem zawk an keng tel bawk. Traditional medication hmanga i dam loh chuan i doctor chuan he damdawi chi hi a dawt leh tur atan a tan tir mai thei che a ni.
Hengte hi intravenous (IV) infusion angin an pe fo thin a, subcutaneous self-injection angin an pe fo bawk. Chutiang injection i hman a ngai a nih chuan i doctor emaw nurse emaw chuan him tak leh dik taka pek dan tur a zirtir ang che.
DMARDs hian side effect a nei em?
Damdawi dang ang bawkin DMARD hian side effect engemaw zat a nei thei a ni. Mahse, mi zawng zawngin an hmu vek lo. Hengte hi damdawi i dawn dan azirin a danglam thei.
Pawimawh: Heng side effects te hi chhiarin hlau suh. I doctor chuan he damdawi hi a pek hmain a hlauhawmna leh a thatna chu uluk takin a teh ang. Harsatna lo awm thei apiang enkawl dan tur a zirtir bawk ang che.
| Side effect chi hrang hrang | Symptoms awm thei te |
|---|---|
| Damdawi chi hnih atanga side effect awm tlangpui | |
| Hri kai theihna a tipung | Immunity a tihhniam avangin khawsik leh flu ang chi infection te hi awlsam takin a lo awm thei a (he risk hi biologics hmang hian a sang zawk). |
| Thisen cell a tlahniam | Thisen var (leukopenia), thisen sen (anemia), platelet (thrombocytopenia) te a tlahniam thei. |
| Liver enzymes a sang hle | Hei hi thisen test hmanga hriat theih a ni. |
| Traditional DMARDs-a side effects bik a awm | |
| Digestive system lama harsatna awm thei | Chaw ei chak lohna, luak chhuak, luak chhuak, pum na, luak chhuak. |
| Vun lama harsatna nei | Vun a hring chhuak. |
| Biologics-a side effects bik a awm | |
| Infection thup lo chhuahna | Tuberculosis leh herpes ang chi natna, tihdam a nih hnua taksaa muhil tawhte chu a lo awm leh thei a ni. |
| Thildang | Cholesterol level sang, thisen zam, injection na hmuna sen emaw, hring emaw hlauhawmna a sang. |
Engtiang chiahin nge he damdawi hian hna a thawh tan?
Hetah hian mi tam takin harsatna an neih chu a awm. DMARDs hi damdawi chi khat, i ei mai mai leh i rilru a hahdam mai mai, natna tidamtu ang chi a ni lo. Heng damdawi te hian kar tlemte atanga thla khat emaw a aia rei emaw chhung chu immune system tihreh nan leh symptoms control nan a hmang thei a ni.
Chuvangin, kar hmasa lamah danglamna lian tham i hriat loh vang mai maia damdawi ei kha bansan suh. Dawhthei taka awm a, doctor-in a sawi angin damdawi hi hman chhunzawm zel a pawimawh hle.
Engtikah nge doctor i hmuh leh a ngaih?
DMARDs i tan hnuah i doctor chuan hunbi neiin a hmu che a ngai ang a, damdawi hian hna a thawk em tih leh side effects a awm em tih a enfiah ang. Hemi chhung hian test thenkhat tih tir a ngai mai thei.
- Thisen test: Damdawi hian hna a thawk em tih te, thin (liver) a nghawng em tih te, thisen cell level a normal em tih te enfiah thin ang che.
- Infection test: Infection thup awm leh awm loh enfiah la, a bik takin biologics i ei a nih chuan.
- Imaging test X-ray ang chi: Hun kal zelah ruh chhiatna a inthlak dan en rawh.
Side effect thar i hmuh chuan, i symptoms a zual a nih chuan, emaw, damdawi chu a hma angin a thawk tha lo niin a lang a nih chuan i doctor hnenah hrilh nghal rawh.
DMARDs hi a tir lamah chuan a buaithlak deuhin a lang thei. Damdawi chi hrang hrang a awm a, hming chi hrang hrang a awm bawk. Mahse, lungngai suh. I doctor chuan i dinhmun nena inmil ber, result tha ber pe thei leh side effects nei tlem ber damdawi combination thlang turin a pui ang che. Zawhna i neih apiang zawt hreh suh.
Take-Home Thuchah a ni
- DMARDs hi damdawi chi khat bik a ni a, autoimmune natna enkawlna atan hman a ni. I immune system tihrehawmin hna an thawk thin.
- Heng damdawi te hian painkiller angin hna a thawk nghal lo. Results hmuh nan kar tam tak emaw thla tam tak emaw a ngai thei. Chuvangin dawhthei la, hmang chhunzawm zel rawh.
- Mi thenkhat chuan mi zawng zawng ni lo mahse, side effect an nei thei. Chuvangin doctor nen inbiak reng a pawimawh hle.
- Dosage pek chu thlak ngai suh la, doctor thurawn tel lovin damdawi ei kha titawp nghal suh.
- I damdawi ei leh damlohna chungchanga zawhna i neih chuan doctor zawt la.
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