Chaw ei harsatna i nei em? Eosinophilic Esophagitis damdawi thar (Dupixent) chungchang i zir dawn teh ang!

I rilru a khar a, ei tur i ei harsat ang maiin i inhriat ngai em? Nangmah emaw i hriat emaw hian Eosinophilic Esophagitis tih natna i nei mai thei. Hming sei tak a ni thei a, mahse i nitin nunah nghawng lian tak a nei thei a ni. Mahse, chanchin lawmawm a awm! He natna enkawlna atana damdawi pawm thar ber chu Dupixent a ni. Vawiin hian awlsam leh chiang takin sawi ila.

A awlsam zawngin, Eosinophilic Esophagitis chu eng nge ni?

Hei hi kan immune system tichhe thei, chronic condition a ni. Ngaihtuah teh, kan taksaah hian natna laka min vengtu cell chi hrang hrang a awm a ni lawm ni? Chutiang thisen var chi khat chu eosinophil an ti a . Min pui tlangpui nachungin, Eosinophilic Esophagitis vei miah chuan heng cell te hi a tam lutuk a, ei tur kan ei chhuahna tube esophagus -ah inflammation a siam thin.

He inflammation hian esophagus a ti na a, a ti tawi bawk. Chuti a nih chuan eng nge thleng? Chaw ei tur chu pum chhunga kal thlak a harsa ta hle. Hei...

• Chaw ei chu ei harsa a lo ni ta.
• Chaw ei tur chu a rilruah a tlakbuak thin.
• Chhung na emaw, kang emaw a awm thei.
• Luak chhuak a awm thei.

Vawi tam tak chu he dinhmun hi ei tur thenkhat allergy nen a inzawm thin.

He natna hi engtin nge Dupixent hian hna a thawh?

A tlangpuiin doctor-te chuan pum chhunga acid tihziaawmna damdawi (Proton Pump Inhibitors) an pe hmasa thin. Entirnan, damdawi ``omeprazole'' leh ``lansoprazole'' te hi i hre tawh mai thei. A chang chuan, inflammation tihziaawmna turin steroid (corticosteroids) an pe bawk.

Mahse Dupixent hian kawng danglam takin hna a thawk thung.

Dupixent a active ingredient chu dupilumab a ni . A awlsam zawngin sawi ila, kan immune system atanga signal lo chhuak, inflammation thlentu protein pahnih interleukin-4 leh interleukin-13 te hnathawh a titawp a ni. Heng signal te hi block a nih chuan esophagus-a eosinophils awm zat a tlahniam a, chu chuan swelling leh inflammation a ti tlem a ni. Hei hian ei harsatna a tiziaawm bawk.

He damdawi chungchanga zirchianna hian eng nge a hmuhchhuah?

He damdawi hi engtiang chiahin nge a thawh hlawk leh a him tih hriat tumin clinical study lian pahnih neih a ni tawh bawk. Heng zirchiannaa tel zawng zawngte hi a hmain thla hnih vel zet proton pump inhibitor hmang tawh, mahse an natna lan chhuahna a ṭhat loh tawhte an ni.

• Zirna hmasa ber: He zirchiannaa telte hi kum 12 chunglam an ni.
• Zirchianna pahnihna: Naupang tê kum 1-11 inkar an tel.

Heng zirchiannaah hian group pakhat chu Dupixent vaccine pek a ni. Group dang chu placebo pek an ni. Hei hi placebo kan ti a . Mahse tumah hnenah damdawi dik tak emaw, placebo emaw an dawng tih an sawi lo.

Engtin nge a rah chhuah?

Thla 4-6 hnua kan thlir kir chuan result hi a fuh tak zet a ni.

1. Eosinophil count: Dupixent ei zinga 60% aia tam chuan an esophagus-a eosinophil cell count nasa takin a tlahniam a, remission an thleng. Hei hi placebo ei zinga 5% vel chauh a ni.

2. Chaw ei harsa: Kum 12 chunglamte zirchiannaah Dupixent ei thinte hian placebo ei thinte aiin ei harsatna an nei tlem zawk tih hmuhchhuah a ni.

He damdawi hi engtin nge ka hman ang?

Dupixent hi liquid a ni. Subcutaneous injection angin pek thin a ni . I doctor chuan kar khatah vawi khat emaw, kar hnih danah emaw pek tur tih chu i kum leh i rih zawng a zirin a rel ang. A tlangpuiin kekawr, pum emaw, kut chunglam emaw-ah pek thin a ni.

He damdawi hi chi hnih a awm a:

• Pre-filled pen: Hei hi hman a awlsam hle. Syringe chungchang ngaihtuah buai a ngai lo.
• Pre-filled syringe: Hei hi naupang tê tê tan hman a ni fo.

Side effects leh engtin nge kan enkawl ang?

Damdawi dang ang bawkin Dupixent hian side effect tenau te a nei thei a ni. Mahse lungngai suh, a tam zawk hi chu manageable an ni.

Hengte hi a side effect langsar ber berte chu an ni. Mahse, thil danglam tak i hriat emaw, harsatna i neih emaw chuan i doctor hnenah hrilh ngei ang che .

Damdawi dangah harsatna a awm thei em?

Ni e, chuvangin he thu hi a pawimawh hle.

• I damdawi ei zawng zawng chu doctor hnenah hrilh rawh: Dupixent i hman tan hmain i damdawi ei zawng zawng (vitamin, herbal remedies, leh supplement te pawh tel) i doctor hnenah i hrilh hmasa tur a ni. Hei hi asthma damdawi i ei a nih chuan a pawimawh hle.
• Vaccine lakah fimkhur rawh: He damdawi ei lai hian vaccine nung thenkhat hi hman a tha lo. Chuvangin vaccine i dawn dawn a nih chuan damdawi i ei tan hmain i doctor nen sawiho hmasa phawt ang che.

Doctor rawn hmasa lovin damdawi ei kha titawp ngai suh , a natna lan chhuah dan chu a na zual leh thei a ni.