Kan taksa hero te tak te: Erythropoietin chungchang zawng zawng!

‘Erythropoietin’ emaw ‘EPO’ emaw tih hi i hre ngai em? I doctor-in a sawi tawh mai thei a, a nih loh leh thisen tlakchham ang chi natna i neih chuan a hming hi i hriat chian deuh pawh a ni thei. Hei hi kan taksaa hormone mak leh pawimawh tak a ni tak zet a ni. Vawiin hian i hriatthiam theih tur awlsam takin kan sawi dawn a ni.

Erythropoietin chu eng nge ni?

A awlsam zawngin sawi ila, Erythropoietin hi i kal atanga siam chhuah hormone a ni ber. A tawi zawngin EPO kan ti bawk. He EPO hnathawh ber chu thisen sen (red blood cells), chu chu thisen sen (erythrocytes) level hrisel taka awm theihna tura puih hi a ni. He EPO hian manager-in kan taksa thisen sen factory-a ‘siam tam zawk siam rawh!’ tih ang maiin hna a thawk a ni.

A châng chuan doctor-te chuan erythropoietin siam chhuah chi khat an hmang a, a bîk takin chronic kidney disease (CKD) vanga thisen tlakchhamna (anemia ) enkawlna atan an hmang ṭhin . Ngaihtuah teh, mi thenkhat kal (kidney) hian hna a thawh that loh avangin he EPO hormone hi an siam chhuak tawk lo. Tichuan thisen tlakchhamna (anemia) an nei ta a ni. Chutih lai chuan he synthetic EPO hian a pui a ni.

Mahse, infiammi ṭhenkhat chuan an khelh ṭhat nan an hmang sual a ni. A chhan chu EPO hian an taksa peng hrang hranga oxygen a thlen tam vang a ni. Chu chu thil tha tak a ni hauh lo, a chhan chu hriselna lama harsatna lian tak a thlen thei a ni.

Erythropoietin hi hming dangin an sawi bawk a, chu chu erythropoietin, hematopoietin, leh hemopoietin te hi a ni. Mahse, a hming hman tam ber chu Erythropoietin leh EPO te an ni.

Erythropoietin (EPO) hian kan taksaah eng nge a tih?

Hei hi zawhna pawimawh tak a ni. EPO hi hormone lian tak a ni a , kan taksa hian thisen sen (red blood cells) a siam thei a ni . Tunah chuan engvangin nge thisen zam (red blood cells) kan mamawh? I thawk chhuah hian i lung chhunga oxygen lo lut chu tuin nge i taksa peng tinah, cell tinah a phur? Chu chu thisen sen (red blood cells) te hian an ti thin. I taksa pum puia oxygen phur truck te tak te angin ngaihtuah rawh. EPO chuan heng truck te hi siam turin a hrilh thin.

Oxygen kan cell-a a thlen chuan chaknaah a chang ta a ni. He chakna hi kan hnathawh zawng zawng atan a pawimawh hle. Tichuan, heng thisen sen (red blood cells) te hian kan cell atanga chhuak carbon dioxide chu lungah an phur leh thin. Chuta tang chuan kan thawk chhuak thin.

A thleng tlangpui chu hei hi a ni: I kal chhunga cell bikte chuan i thisenah oxygen level a hniam tih an hre thin. Chu chu an hriat chuan EPO an siam chhuah chu an tipung ta a ni. He EPO hian kan ruh spongy part, bone marrow -ah a kal a, ‘Okay, tunah chuan red blood cells tam zawk siam rawh!’ a ti a.

Mahse, kal chhunga cell-te hian thisenah oxygen a awm tawk tih an hriat chuan EPO siam chhuah a ti tlem a ni. Hei hi supply-demand system ang mai a ni. Taksain a mamawh hunah an thar chhuak tam a, mamawh a tlem laiin an siam chhuak tlem bawk.

Hetiang thil hi kan taksaah a lo thlen dan hi a mak lo em ni? Engkim hi a ruahman fel em em a ni!

Damdawi lam thil thenkhat chuan kal (kidney) atanga EPO siam chhuah zat a nghawng thei a ni. Hei hian EPO tam lutuk a siam thei a, a tling lo thei bawk. Heng pahnih hian thisen sen (red blood cells) a inthlauhna a thlen thei a ni.

Erythropoietin (EPO) level a san chuan eng nge thleng ang?

EPO level hi a tul lova a san chuan, chu chu taksain a mamawh tak tak aia tam EPO a siam chhuah chuan thisen sen (red blood cells) pawh a pung dawn tihna a ni. Hei hi polycythemia kan ti a ni . A awlsam zawngin, thisenah hian thisen sen (red blood cells) a tam lutuk a. Hei pawh hi harsatna a ni a, a chhan chu thisen a thim a, thisen zam a awm thei a ni.

Engvangin nge erythropoietin (EPO) level hi a san?

EPO level hi a tul lo taka a san theihna chhan hrang hrang a awm a:

• Oxygen level hniamna hmuna hun rei tak awm: Ngaihtuah teh, mi pakhatin meizial a zuk chhunzawm chuan an taksaa oxygen a thlen zat chu a tlem hle. Tichuan kal (kidney) te chuan, ‘Aw, oxygen a awm lo, red cell tam zawk kan siam a ngai a ni,’ tiin an ngaihtuah a, EPO an siam tam zawk a ni. Chutiang bawkin mi pakhat chu Nuwara Eliya ang hmun sang takah hun rei tak a awm chuan chuta boruaka oxygen level hniam vangin EPO level pawh a sang thei bawk. Mahse hetiang hmun sang takah hian EPO a pung hi thil pangngai a ni a, taksa insiamremna a ni.
• Kal natna avanga thisen tlakchhamna (anemia): A chang chuan thisen tlakchhamna hi kal harsatna avanga lo awm a ni lo. Mahse thisen zam (red blood cells) a tlem lutuk vang emaw, thisen sen (red blood cells) te hian hna an thawh that loh avangin kal (kidney) te hian oxygen an dawng tlem hle tih an hre thei a ni. Chuti chung pawh chuan thisen sen siamna atana pui turin EPO tam zawk an siam chhuak thin. Hei hi a takah chuan taksain a chhan dan pangngai a ni.
• Tumor chi hrang hrang: A tlem hle nachungin, tumor chi thenkhat chuan kal atanga EPO tam lutuk a chhuah tir thei a ni.

Erythropoietin (EPO) level a tlahniam chuan eng nge thleng ang?

EPO level tlahniam chhan ber chu chronic kidney disease (CKD) a ni. Sawi tawh angin kal (kidney) a chhiat chuan EPO a siam tha thei lo. Hei hian EPO level a tihhniam phah a ni. Hetiang dinhmun, CKD, leh EPO level hniam hian thisen tlakchhamna a thlen thei a ni. Chumi awmzia chu i chau a, i sen hring a, thawk harsatna i nei thei tihna a ni.

Engvangin nge erythropoietin (EPO) level hi a tlahniam?

A chhan ber chu CKD ni mah se, a chhan dang a awm. Chu chu Polycythemia Vera an tih natna a ni. Hei hi thisenah cancer chi khat a ni. Genetic mutation avang hian ruhro hian thisen sen (red blood cells) a siam tam lutuk a. Tichuan, kal (Kidney) chuan, ‘Aw, thisenah hian thisen sen (red blood cells) a tam lutuk a, EPO siam kan ngai tawh lo’ tiin an hria a. Chuvangin EPO siamchhuahna an tihtlem phah a ni. Hei hi EPO hniam chhan pawh a ni.

EPO level a hniam chuan eng treatment nge tih theih ang?

EPO level a hniam chuan a chhan bulpui enkawlna hmanga enkawl a ni . Chu chu kal natna a nih chuan enkawl a ni a, a chhan dang a nih chuan enkawl a ni.

Mahse, EPO level hniam vanga thisen tlakchhamna (anemia) enkawlna ber chu recombinant erythropoietin a ni. Chungte chu erythropoietin-stimulating agents (ESAs) an ti bawk. Hengte hi EPO hormone synthetic version, lab-a siam a ni. Doctor ten EPO gene chu clone in injection angin an pe che a ni. Chumi hnuah i taksaah a lut a, i ruhro chu a tichak a, thisen sen tam zawk siam tan a ni.

He enkawlna hi chronic kidney failure avanga thisen tlakchhamna (anemia) enkawlna atana pek a ni ber. Cancer chi hrang hrang hmuh tur awm lo thenkhat tan pawh pek thin a ni.

Mahse heng ESA te hian side effect thenkhat a nei thei a:

• Thisen sang a sang
• Khawsik
• Luak chhuak thei
• Luhai
• Injection na hmuna natna

Chuvangin he damdawi hi a dose dik takah ei a pawimawh hle a, doctor thurawn angin ei a ngai hle.

Engtin nge erythropoietin (EPO) level hi an teh thin?

I doctor chuan thisen test awlsam tak hmangin i EPO level a teh thei ang. He thisen test hian i thisen cell-a EPO chhuahna tichhe thei thil danglamna a hmuchhuak thei a ni. Hei hian polycythemia, anemia emaw, ruhro natna dang emaw i neih leh neih loh hriat theih nan a pui thei a ni.

Doctor emaw nurse emaw chuan i kut ah vein a thlang ang a, chutah chuan vun chu iodine emaw isopropyl alcohol ang chi thil hmangin a tifai ang. Tichuan, needle te tak te (21 gauge needle - earring tip aia te deuh deuh) chuan i vein atanga thisen sample tlemte a la ang. Thisen sample hi lab-ah enfiah turin thawn a ni ang.

Lab result a luh veleh i doctor chuan a chungchang a sawipui ang che a, zawhna i neih apiang a chhang ang che. I EPO level chu normal range chhungah awm mah se, enkawlna dang i la mamawh thei tih hre reng ang che. Chu chu i doctor-in a rel ang.

Erythropoietin (EPO) level pangngai chu eng nge ni?

Doctor-te chuan EPO hi milliliter khatah milliunit (mU/mL) -in an teh thin . Mi hrisel tak EPO level hi 4 atanga 26 mU/mL inkar a ni thei.

Mahse heng hlutnate hi i ta a ni:

• Kum
• Mipa leh hmeichhe thliarna
• Hriselna dinhmun zawng zawng

Thil engemaw zat a zirin a danglam thei a, chungte chu: Chuvangin, i doctor chauhvin i result chu dik takin a hrilhfiah thei a, hrisel range chhungah emaw, pawnah emaw a awm tih a hrilh thei che a ni. Chuvangin, Internet-a thil awmte a\angin nangmah ngeiin diagnosis siam suh.

Erythropoietin (EPO) level hi natural takin tihsan theih a ni em?

Chronic kidney disease (CKD) emaw, thisen tlakchhamna (anemia) i neih chuan EPO level hniam tak i neih chuan ei leh in leh nunphung tihdanglamna thenkhat chuan i EPO level tlem a tisang thei a ni. Amaherawhchu, hengte hi damdawi lam thurawn bâkah tih tur a ni a, inenkawlna thlaktu atan tih tur a ni lo.

• Exercise: Research atanga a lan dan chuan exercise i tih fo hian, a chakna tlem berah chuan i taksain oxygen a hmang tam zawk a ni. Chumi hnuah i thluak chuan i taksa chu ‘EPO tam zawk siam’ turin a hrilh a ni. Cycle khalh, jogging, leh tui chawi te hi hetiang exercise chi hrang hrang entir nan hian a tha hle.
• Dietary iron: Iron hi kan thisen sen (red blood cells)-a hemoglobin awm tam tak a ni. He hemoglobin hi oxygen phurtu a ni. Thir tamna ei tur kan sawi hian kan khuaa kan neih sa sen, artui hring, legumes, leh thlai hring, spinach ang chi te pawh kan sawina a ni. Tofu, iron-fortified cereals, flour, leh chhang pawh hian iron a pai bawk.

Heng thil bakah hian ei leh in inthlau tak ei te, tui in tam te, meizuk loh te ang chi te pawh hi i hriselna zawng zawng atan a tha a, indirect takin i EPO level atan pawh a tha hle bawk.

A tawp berah chuan i hriat reng tur thilte

Erythropoietin (EPO) hi hormone pawimawh tak a ni a, kan ruhro hi ‘thisen sen tam zawk siam’ turin a hrilh a ni.

A châng chuan, kan taksa hian thisen zam (red blood cells) a siam tam lutuk a, a nih loh leh a tling lo. Heng pahnih hian hriselna lamah harsatna a thlen thei a ni. I doctor chuan i thisenah EPO awm zat chu thisen test hmangin a enfiah thei a, a tul chuan enkawlna dik tak a pe thei bawk. Chuvangin, thisen tlakchhamna (chau, paleness, thawk hahna) symptoms i neih chuan, kidney lama harsatna i neih chuan doctor thurawn la ngei ang che. Anni chuan kawng dik takin an pui ang che. Hrisel takin awm rawh!