Accident na tak i tawk tawh emaw, operation hnuah thisen chhuak nasa tak i nei emaw tih han ngaihtuah teh. A chang chuan, a hma anga thisen pek mai mai hi a tawk lo. A bik takin i thisen a khai tha lo a nih chuan i doctor chuan enkawlna bik FFP tih chu pek che a tum mai thei. A hming i hriat chuan i hlau deuh mai thei. Mahse, lungngai suh. Vawiin hian FFP chu eng nge a nih, engvangin nge a pek tih leh a chungchanga hriat tur zawng zawng chu awlsam takin kan sawi dawn a ni.
FFP (Fresh Frozen Plasma) hi eng nge ni?
A awlsam zawngin sawi ila, FFP hi mi thisen pek atanga cellular components, red blood cells leh white blood cells te lakchhuah hnua a awm reng, yellowish liquid portion a ni. Hei hi plasma kan tih chu a ni .
He plasma hian kan thisen volume a vawng reng a ni. Tin , "clotting factors" an tih protein bik a pai bawk a, chu chuan kan hliam a nih chuan thisen chhuah a titawp thei a ni.
Chuvangin, mi pakhatin heng clotting factor pakhat emaw, a aia tam emaw a tlakchham a, thisen a chhuah tam lutuk chuan FFP pek a ni a, chu chuan thisen volume hloh chu a siam tha leh a, a depleted clotting factors chu a tikhat leh a ni.
Hei hi "Fresh Frozen" Plasma an ti a, a chhan chu thisen pek atanga plasma a inthen hnuah darkar 8 chhungin -18 degree Celsius aia hniam temperature -ah deep frozen a ni a , chu chuan a chhunga clotting factor hlu tak takte chu a humhim thei a ni.
Hei hi hming dang a awm em?
Ni e, doctor ten he enkawlna chungchang an sawi hian hming dang an hmang thei a ni. Chu hmingte chuan a humhalhna atana hman dan a kawk a ni. Entirnan, PF24, PF24RT24 tih ang chi hming a awm.
Heng hming leh technical details te hi ngaihtuah lutuk suh. I doctor chuan i dinhmun nena inmil ber leh i mamawh clotting factors awmna plasma chi dik tak a thlang ang.
Tute nge FFP enkawlna mamawh?
FFP hi thisen chhuak zawng zawng tan enkawlna a ni lo. Enkawlna dangin hna a thawh lohna hmun bik takah hman a ni tlangpui. FFP mamawhna tur dinhmun pawimawh thenkhat chu hetiang hi a ni:
- Thisen zam (blood clotting factors) tlakchhamna: Mi pakhatin pianpui atanga thisen zawrhna (blood clotting factors) tlakchhamna nei, hemophilia ang chi, thisen a chhuah tam lutuk hian.
- Warfarin ei thin tan: Warfarin hi thisen tithianghlimtu a ni. He damdawi eitu mi pakhatin thisen a chhuah tan chuan vitamin K pek hian a thunun tlangpui a, mahse vitamin K hian nghawng a neih thuai loh chuan FFP hi a puitu atan pek theih a ni
- TTP (Thrombotic Thrombocytopenic Purpura) tih natna a awm chuan:Hei hi thil awm lo tak a ni. Taksaah thisen zam hlauhawm tak tak a siam thin. FFP pek hian heng damlote hi enzyme bo thlakna tur pek an ni.
- Thisen chhuah tam lutuk: Accident lian tak, surgery emaw, thil dang emaw avanga taksa atanga thisen tam tak a bo chuan thisen pekna kawngah FFP hi pek a ni.
Engtin nge FFP hi pek a nih?
He enkawlna hi damdawi inah tih a ni tlangpui. FFP bag frozen chu i taksaah i inject hmain room temperature-ah a thaw hmasa thin. A kalphung chu hetiang hi a ni:
1. Cannula dah luh: Doctor emaw nurse emaw chuan i kut vein pakhatah cannula (IV line) a thun ang.
2. FFP pek: FFP bag hi he cannula nena inzawm a nih chuan plasma chu i vein kaltlangin i taksaah zawi zawiin a lut a.
3. Monitoring: Hemi chhung hian i vital signs , heart rate leh blood pressure te chu enfiah chhunzawm zel a ni ang. Thisen test, PT/INR leh PTT te pawh tih theih a ni a, chu chuan i thisen a khalh tha em tih enfiah a ni thei bawk.
4. Dosage: FFP bag (unit) pakhatah hian 200-250 ml vel a awm a. Taksa hnena pek tur hian minute 30 vel a ngai a ni. Thisen hloh zat a zirin i doctor chuan FFP bag engzat nge i mamawh tih leh eng chen nge i mamawh tih a rel ang.
FFP hian eng hlauhawmna leh harsatna nge a neih?
Damdawi dang ang bawkin FFP peknaah hian hlauhawmna tlemte tak tak a awm a. Mahse doctor-te chuan heng hlauhawmnate hi an hre chiang hle a, a ven theih nan fimkhur zawng zawng an nei a ni. Tin, thisen pek bag tin hi uluk taka test a nih avangin tunah chuan natna hrik kai theihna a tlahniam tawh hle bawk.
| Risk/Complication awm thei | Hrilhfiahna awlsam tak |
|---|---|
| Allergy natna a awm thei | Immune system hian taksa chhunga plasma lut chu a chhang let thin. Hei hian symptom tenau te, vun rawng leh vun natna te a thlen thei a ni. |
| Infection awm thei te | Donor thisen atanga virus kai theihna chance a tlem hle. Mahse, hei hi a tlem hle a, Sri Lanka-a blood bank-te thisen pek zawng zawngte chu uluk taka test vek a nih avangin. |
| TRALI (Transfusion avanga lung hliam na tak) 1.1. | Hei hi a tlem hle a, mahse pawi tak a ni a, lungah a hring thei a, thawk harsa a ti thei bawk. |
| TACO (Transfusion avanga thisen kalna a tam lutuk) . | Vawi khata taksaa tui (plasma) lut tam lutuk avangin circulatory system hian phurrit lian zawk a nei a ni. Hei hian thisen sang a tisang thei a, lungah tui a khat thei bawk. |
Enkawlna hnuah eng nge thleng a, engtikah nge damdawi lam thurawn i lak ang?
I dam leh theih hun chhung hi FFP i tih chhanah a innghat a ni. A tlangpuiin, enkawl hnu ni khat vel chu i rilru a hahdam deuh tan ang. Chawlh hahdam tam tak neih a pawimawh hle .
A châng chuan, damdawi ina i haw hnuah pawh side effect ṭhenkhat a awm thei. Chuvangin a hnuaia condition te hi fimkhur rawh.
| Nihna | Eng nge tih tur |
|---|---|
| Heng symptoms te hi i neih chuan doctor nen inbia ang che. | |
| Hengte hi allergy chhinchhiahna a ni tlangpui. I doctor hriattir a pawimawh. |
| Heng symptoms te hi i neih chuan damdawi in Emergency Treatment Unit (ETU) ah kal nghal tur a ni. | |
| Hengte hi TRALI emaw TACO emaw ang chi natna khirh tak chhinchhiahna a ni thei. Hengte hi enkawlna pek a nih atanga darkar 6 hmasa berah a thleng thei a ni. Hun khawhral lova inenkawlna zawng nghal a pawimawh. |
Take-Home Thuchah a ni
- FFP hi damdawi lam enkawlna pawimawh tak a ni a, thisen chhuak nasa tak a awm chuan nunna a chhanhim thei a ni.
- Hei hian a bik takin thisen zam (blood clotting factors) leh taksaa thisen volume hloh tawhte siam\hat lehna a huam ber a ni.
- He inenkawlna hi damdawi inah leh damdawi lam enkawlna hnuaiah pek a nih avangin ṭul lova hlauh a ngai lo.
- Damdawi zawng zawng ang bawkin hlauhawmna tenau tak tak a awm a, mahse doctor-te chuan enkawl turin an inpeih reng a ni.
- Inenkawl zawha natna lanchhuahna pawi tak, thawk harsa ang chi i neih chuan damdawi in Emergency Department (ETU) pan nghal rawh.
- Hemi chungchangah hian zawhna emaw, ngaihtuahna emaw i neih chuan i doctor nen sawiho hreh ngai suh.
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