Kan taksa chhunga thisen hi khawi atanga lo chhuak nge, engtin nge siam a nih tih i ngaihtuah ngai em? He thisen hi kan hriselna tur te, natna laka min venhimna tur te, kan taksa peng tinah oxygen thlentu tur te a pawimawh zia kan hria. Chuvangin vawiinah hian he thil mak tak hi kan sawi dawn a, chu chu kan taksa hian a mah chauhin thisen cell thar a siam tihna a ni. Taksa chhunga factory te tak te ang mai a ni.
Hematopoiesis tih hi eng nge ni?
A awlsam zawngin sawi ila, Hematopoiesis hi kan taksa chhunga thisen cell siam chhuahna a ni. Thisen cell hlui an thih rualin, a thlaktu tur thisen cell thar siam chhuah reng a ngai a ni. An tel lo chuan kan thisen supply a tichhe dawn a ni. Hetiang kalphung hi kan pian hma atang hian a intan a, kan dam chhung zawngin cycle khatah a kal zel a ni.
He thumal hi a buaithlak deuhin a lang thei a, mahse a awmzia erawh a awlsam hle. Grik thumal pahnih atanga siam a ni a:
- Haîma (Haima): tih awmzia chu "thisen" tihna a ni.
- Poiēsis: tih awmzia chu "thil siam" tihna a ni.
Tunah chuan i hrethiam tawh a ni lawm ni? Heng thumal pahnih hi an inzawm khawm chuan "thisen siam" tihna a ni. A chang chuan hemi atan hian `(hemopoiesis)` leh `(hematogenesis)` tih ang chi thumal hman a ni bawk.
Hetianga thisen cell siam chhuah chi hrang hrangte chu engte nge ni?
Kan thisen hi cell chi hrang hrang inzawmkhawm atanga siam a ni. Heng cell chi hrang hrang zawng zawng hi hematopoiesis kalpui lai hian siam chhuah vek a ni. A chi lian ber berte chu eng nge ni tih leh an hnathawh dan tur i lo en ang u.
| Thisen cell chi hrang hrang | Hnathawh chu a awlsam hle. |
|---|---|
| Thisen sen emaw Erythrocyte emaw a awm | Chungte chu kan lung atanga oxygen la chhuakin taksa peng leh cell dang zawng zawngah a phurh chhuaktu ‘delivery service’ an ni. Cell-te siam carbon dioxide bawlhhlawh chu lungah an phur kir leh bawk. Kan thisenah hian thisen sen (red blood cells) a tam ber. Hengte siam dan hi Erythropoiesis an ti a . |
| Thisen var emaw Leukocyte emaw a awm | Hengte hi kan taksa ‘sipai’ an ni. Heng thisen var te hian natna laka min venghim a, hnam dang rawn lut, hrik, bacteria leh virus te chu an do a ni. Taksa chhunga cell pangngai lo awmte tihchhiat nan an pui bawk. An siam dan chu leukopoiesis an ti a . |
| Platelet emaw Thrombocyte emaw a awm thei | I kut i tan chuan eng nge thleng ang tih han ngaihtuah teh. Rei vak lo hnuah thisen chhuak chu a reh ta a ni lawm ni? Chu chu heng platelet te hian an puih a ni. Hengte hi cell fragment sticky tak tak an ni. Hliam a awm chuan an inzawm khawm a, clot an siam a, thisen chhuah chu a titawp thin. Hengte siam dan hi thrombopoiesis an ti a . |
Thisen var chi hrang hrang a awm em?
Ni e, kan sipaiah ang bawkin thisen var chi hrang hrang a awm a. An vai hian hna bik an nei vek a. A chi hrang hrangte chu:
- Neutrophils te pawh a awm
- Basophils te hi an ni
- Eosinophils a awm bawk
- Monocytes te hi a awm a
- Lymphocytes - Hengte hi B-cells, T-cells, leh Natural Killer cells-ah te an inthen leh a.
Khawiah nge he thisen siam hi a awm tak tak?
Heng thisen cell siamtu factory ber chu kan ruhro chhungah a awm a . Bone marrow hi kan ruh lian tak tak chhunga tissue nem tak, spongy ang maia awm chu a ni. Thisen cell te hi ruhro (bone marrow) ah siam a ni a, chu chuan kan thisen kalna kawngte chu a zawm ta a ni.
Thisen hi a tlangpuiin ruhroah siam ni mah se, thil bik thenkhatah chuan, entirnan, ruhro hian thisen a siam theih lohna tur natna a neih chuan kan thin leh ril ang chi taksa peng hrang hrangte pawhin thisen an siam tan thei bawk.
Mahse he thisen chhuahna hmunte hi kan pian hma leh kan pian hnuah pawh a inang lo deuh a ni.
Nau piang hma (nausen stage-a awm) .
Naupai kar hmasa lamah chuan thisen hi yolk sac an tih structure-ah a lo chhuak thin. Tichuan, naupai a kal zel chuan he hna hi thin leh rilruah a kal ta a ni. Naupai thla nga velah chuan ruhroah thisen a chhuak tan ber a ni.
Pian hnuah
Kan pian ni atanga puitlin thleng hian ruhro hi thisen cell siamna hmunpui ber a ni. Mahse, thisen var chi khat lymphocyte an tih pawh hi ruhro bakah hian lymphatic system-a tel thymus ang hmunah a lo piang chhuak bawk.
Engtin nge hematopoiesis kalphung hi a lo awm?
He thil kalphung zawng zawng hi cell bik pakhat atanga tan a ni. Hei hi Hematopoietic Stem Cell (HSC) an ti a.Hei hi "mother cell" emaw "primary cell" emaw ti ila. He nu cell hi thisen sen, thisen var, platelet, thisen cell chi hrang hrangah a chang thei a ni.
Hei hi leilung hnim hring ang maiin han ngaihtuah teh. Bêl siamnaah pawh leilung hnah khat hmanga bêl, plate emaw, thil dang emaw siam theih a nih ang bawkin, he HSC cell aṭang hian thisen cell eng pawh siam theih a ni.
He HSC cell hi a hmasa berin "precursor" cell a lo ni ta a ni. Chumi hnuah chuan he precursor cell hi vawi tam tak a inthen darh a, a danglam leh a, a tâwpah chuan thisen sen, thisen var, a nih loh leh platelet lo puitling tak a lo ni ta a ni.
- Thisen sen siam chhuah (Erythropoiesis): HSC cell hi a hmahruaitu cell ``erythroblast'' an tih ah a lo thang lian a, a tawpah chuan thisen sen a lo ni ta a ni.
- White blood cell siam chhuah (Leukopoiesis): Hetah hian siam chhuahna kawng pahnih a awm a. Thisen var thenkhat chu ``myeloid cell line`` kaltlangin an siam a, lymphocyte te chu ``lymphoid cell line`` kaltlangin an siam bawk.
- Platelet siam chhuah (Thrombopoiesis): HSC cell hi cell lian takah a lo thang lian a, chu chu ``megakaryocyte'' an ti a ni.Tichuan, he cell lian tak atang hian platelet te chu a inthen darh a.
Hetiang kalphung hi harsatna a awm a nih chuan engtin nge ni ang?
Kan taksa hian heng thisen cell siamchhuahna hi a thunun thiam hle a ni. Chu chu kan mamawh cell zat chauh kan siam tihna a ni. Mahse natna thenkhat chuan he process hi a ti buai thei a ni. Tichuan thisen cell tlem lutuk emaw, tam lutuk emaw siam chhuah theih a ni. Heng zinga pakhat mah hi taksa tan a tha lo.
| Thisen cell chi hrang hrang | Cell zat a tlahniam chuan (Too Few) . | Cell a pun chuan (Too Many) . |
|---|---|---|
| Thisen sen (red blood cells) a awm | Hetiang dinhmun hi anemia an ti a . Taksa cell ten an mamawh oxygen an hmuh loh avangin taksa chu a chau a, chak loin a inhria. | Hetiang dinhmun hi Erythrocytosis an ti a . Thisen a ti thim thei a, heart attack emaw stroke emaw ang chi natna a thlen theihna a tipung thei a ni. |
| Thisen var (white blood cells) a awm | Hetiang dinhmun hi Leukopenia an ti a . Thisen var (white blood cells) a tlakhniam chuan kan taksain a venghimna (immune system) a chak lo a, infection a awm fo thei bawk. | Hetiang dinhmun hi Leukocytosis an ti a . Infection i do laiin a thleng tlangpui. Mahse thisen natna thenkhatah emaw cancer natna thenkhatah pawh a awm thei bawk. |
| Platelets a awm | Hetiang dinhmun hi Thrombocytopenia an ti a . Hliam tenau tak pawh hian thisen chhuah a titawp thei lo. Taksaah pawh hliam a awm thei bawk. | Hetiang dinhmun hi thrombocytosis an ti a, thisen kalna kawng chhunga thisen zam hlauhawm tak siam theihna a tipung a ni. |
Eng dinhmun nge hematopoiesis kalphung tibuaitu?
He thisen siam dan hi chhan hrang hrang avangin a tibuai thei a ni.
- Kum upa lam: Kan tar chhoh zel chuan ruhro (bone marrow)-a thau awm zat a pung thei a, chu chuan thisen cell siam theihna a ti tlem thei a ni.
- Thisen natna leh cancer: Cancer, leukemia, lymphoma, myeloma te hian thisen cell pangngai lo tam tak a siam thei a, chu chu a thawk tha lo hle.
- Damdawi \henkhat: Entîr nân, cancer damdawi chemotherapy hian cancer cell chauh ni lovin thisen hrisel tak takte pawh a that thei a ni. Hei hi damdawi thenkhat side effect a ni.
Chau reng reng, khawsik leh natna hrik kai fo thin, chhan awm lova hliam, emaw, hliam atanga thisen chhuak, tihtawp hun rei tak nei ang chi symptoms i neih chuan doctor nen inbiakna neihpui ngei ang che. Chûngte chu thisen lama harsatna nei chhinchhiahna a ni thei.
Hematopoiesis hi kan dam khawchhuahna atana thil pawimawh tak, thil awm reng a ni. Kan ruhro chhunga factory te tak te hi kan hriselna leh chakna siamtu a ni. Chuvang chuan kan thisen hriselna enkawl hi a pawimawh em em a ni.
Take-Home Thuchah a ni
- Thisen siam chhuahna (Hematopoiesis) a niKan taksain thisen cell red blood cells, white blood cells, leh platelets an tihte a siam chhuah dan a kawk a ni.
- Hetiang thil hi kan ruh chhunga ruhro (bone marrow) -ah a thleng ber a ni.
- Thisen sen (red blood cells) hian oxygen a keng tel a, thisen var hian natna lakah min veng a, kan hliam hian platelet te hian thisen chhuah a titawp bawk.
- Thisen cell count pangngai aia hniam emaw, sang emaw chuan damdawi lam harsatna hrang hrang a thlen thei a ni.
- Sawifiah loh taka hah lutuk, natna hrik kai fo emaw, thisen chhuah dan pangngai lo emaw ang chi symptom i neih chuan doctor pan vat a, thurawn lak a pawimawh.
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