I taksaah lumps i nei em? Hodgkin Lymphoma a ni thei ang em? Kan sawi dun teh ang!

I kawr, i kawrfual, a nih loh leh i kawrfual-ah hnah te tak te i hmu tawh em? A nih loh leh ni tam tak chhung chu i chau hle tawh em, a nih loh leh khawsik i nei nghal em? A châng chuan hengte hi thil pangngai a ni thei bawk. Amaherawhchu, heng symptoms te hi i neih chuan tlem tal ngaihtuah a tha. A chhan chu hengte hi Hodgkin Lymphoma an tih natna chhinchhiahna a ni thei a ni. A hming hi hlauhawm tak angin lang mah se, hei hi natna enkawl leh tihdam theih a ni fo. Chuvangin, vawiin hian Hodgkin Lymphoma chungchang chipchiar takin kan sawi dawn a ni.

Hodgkin Lymphoma hi eng nge ni?

A awlsam zawngin, Hodgkin Lymphoma hi cancer chi khat a ni a, kan lymphatic system , kan taksaa hrik dotu system-ah a lo awm a ni. Tun hma chuan Hodgkin’s disease an ti bawk. Lymphoma hi chi hnih a awm a. Pakhat chu Hodgkin lymphoma a ni a, pakhat chu Non-Hodgkin Lymphoma a ni. Heng cancer pahnih hian kan taksa hriselna atana pawimawh , thisen var chi khat lymphocytes a nghawng a ni.

Hodgkin lymphoma hi kan B lymphocytes (B cells) genes a mutation vang a ni. Heng inthlak danglamna te hi dam chhung zawngin a thleng thin. A tam zawkah chuan he lymphoma hi kawr emaw, rilru chhunga lymph node-ah emaw a intan thin. A châng chuan, armpits, groin, abdomen, pelvis-a lymph node-ah pawh a lo awm thei bawk.

Thu lawmawm tak chu Hodgkin lymphoma vei enkawl leh dam rei zawkte hi kum tin an pung zel a ni. Thil tam takah chuan enkawlna hian Hodgkin lymphoma chu a tidam vek thei a ni. Mahse, a chang chuan natna hi a lo awm leh thei a ni. Chutiang a nih chuan damdawi lam zirchiangtute chuan enkawlna thar an zawng reng a ni.

Hodgkin Lymphoma chi hrang hrangte chu engte nge ni?

Hodgkin lymphoma hi chi li a awm a. Eng nge an nih hi han thlir ila:

• Nodular sclerosis Hodgkin lymphoma: Hei hi Hodgkin lymphoma chi khat zingah chuan a tam ber a ni. Thalai, a bik takin hmeichhiaah a awm tam zawk. A tam ber chu rilru chhunga lymph node te a ni.
• Mixed cellularity Hodgkin lymphoma: Hetiang chi hi kum 60 hnuai lam ah a awm tlangpui. A chang chuan pum (belly) ah a lo awm thei bawk.
• Lymphocyte-rich classic Hodgkin lymphoma: Hetiang chi hi Hodgkin lymphoma vei zinga 6% velin a awm thin. Mipaah ​​a tam zawk.
• Lymphocyte-depleted Hodgkin lymphoma: Hei hi a tlem hle. Hodgkin lymphoma vei zinga 1% velin a awm thin. Kum 60 chunglam leh...Hei hi HIV/AIDS vei zingah a tam zawk thei.

Hodgkin Lymphoma hi engtiang chiahin nge a awm?

Hodgkin lymphoma hi natna hmuh tur awm lo tak a ni . Kum tin mi 100,000 zinga pathum vel chauh a nghawng a ni. Mahse mak tak maiin naupang leh puitling kum 15 leh 19 inkar cancer chi khat zingah chuan a tam ber a ni.

Mahse, Hodgkin lymphoma hi non-Hodgkin lymphoma aiin a tlem zawk hle.

Hodgkin Lymphoma natna lan chhuahna chu engte nge ni?

Hodgkin lymphoma chhinchhiahna hmasa ber chu a kawr, a kekawrte, a nih loh leh a kawrfual (groin)-a lymph node natna nei lo, a hring chhuak a ni . Chu bakah, a lan chhuah dan dang engemaw zat a awm thei bawk:

• Persistent fatigue: Ni engemaw zat chhung chu a hma aia chau zawka inhriatna. I taksa hian chakna a nei lo ang maiin.
• Hriselna hriat loh: Khawsik sang tak, darkar hnih chhung in lama enkawl hnua a reh loh emaw, ni hnih aia rei emaw a awm chuan thil pawi tak a nihna chhinchhiahna a ni thei.
• Zan lama thawk hah lutuk: Zan lama thawk hah lutuk a, puan leh thawmhnaw a hnim.
• Sawifiah loha taksa rihna tihtlem: Thawhrimna tel lova taksa rihna tihtlem. Thla ruk chhunga i taksa rihna zawng zawng atanga 10% aia tam i tihtlem chuan ngaihtuahawm tak a ni.
• Itching (Pruritus): Mi thenkhat chuan zu in emaw, inbual emaw hnuah vun a na lutuk thin.
• Pum na emaw, pum na emaw: Pum na zawng zawng hi natna khirh tak chhinchhiahna a ni vek lo. Mahse, pum na, na tak, reh lo i neih chuan doctor pan rawh.
• Chest pain: He symptom hi Hodgkin lymphoma hi lung tissue emaw, rilru chhunga lymph node emaw-ah a awm chuan a awm thei.
• Thâwk harsa: Hei hi lung chhunga Hodgkin lymphoma emaw, rilru chhunga lump lian tak emaw chhinchhiahna a ni thei.

Doctor-te chuan heng symptom pathum—khawsik, taksa rihna tlahniam, leh zan lama thawk hah—"B symptoms" an ti bawk. Heng symptoms awm hian doctor te chu i prognosis leh treatment ruahman turin a pui thin.

Eng thilin nge Hodgkin Lymphoma hi a thlen?

Kan sawi tawh ang khan Hodgkin lymphoma hi i B cells- a genetic change a awm hian a lo awm thin . Heng inthlak danglamna te hi i pianpui thil a ni lo va, dam chhunga i neih chhuah thil a ni.

Hetianga B cells an inthlak chuan cancer cell chi khat, cell pangngai aia lian zawk an siam chhuak thin. Chungte chu Reed-Sternberg cells an ti a. Heng Reed-Sternberg cell te hian cytokines an siam chhuak thin.Heng cytokines te hian cell pangngai te chu cell pangngai lo awmna lymph node ah an hip lut thin. Tichuan, heng cell pangngai atanga thil chhuak te hian Reed-Sternberg cell te chu a ti lian lehzual a ni. Hei hian lymph nodes a ti hring chhuak thin.

He cancer hi i lymphatic system kaltlangin lymph node dang, thymus leh spleen -ah te a darh thei a ni. Taksa pumpuiah lymph node-ah a darh thei bawk. A tlem berah chuan taksa peng dang, lung, thin, leh ruhro .

Risk factors te chu engte nge ni?

Doctor-te chuan Hodgkin Lymphoma vei theihna tipungtu thil engemaw zat an hmuchhuak a:

• I kum: Kum 20 leh 39 inkar, a nih loh leh kum 65 aia upa i nih chuan he natna hi i vei theihna a sang zawk.
• I mipa leh hmeichhia: Mipa hian Hodgkin lymphoma an vei tam zawk. Mahse, a hmaa kan sawi tawh chi, nodular sclerosis hi hmeichhiaah a tam zawk.
• I chhungkaw damdawi lam chanchin: I unaute emaw, i nu leh pate emaw Hodgkin lymphoma an vei tawh a nih chuan nang pawhin i vei theihna chance a sang deuh hlek a ni.
• Organ transplant i neih tawh chuan: Organ transplant i neih tawh chuan antirejection damdawi i ei a ngai dawn a, chu chuan lymphoma vei theihna a tipung a ni.
• Viral infection thenkhat: Viral infection HIV , human T-lymphotropic virus type 1, emaw Epstein-Barr virus te neih hian Hodgkin lymphoma vei theihna a tipung thei a ni.

Engtin nge Hodgkin Lymphoma hi hmuhchhuah a nih?

Doctor chuan taksa lamah a enfiah hmasa ang che, Hodgkin lymphoma chhinchhiahna, lymph node hring ang chi te a enfiah ang. Tin, i hriat tawh danglamna eng pawh, khawsik reng reng emaw, sawifiah theih loha i taksa rihna tlahniam emaw te pawh an zawt bawk ang. Hodgkin lymphoma hriat theihna turin test eng emaw zat tih theih a ni. Chûng zîngah chuan thisen test te, imaging test te, leh biopsies te pawh a tel thei a ni .

Thisen test a ni

Thisen test hian i doctor hnenah i hriselna zawng zawng a hriattir thei a ni. Cancer chhinchhiahna an hmuchhuak thei bawk. Test i neih ṭhenkhat chu:

• Complete blood count (CBC): Hei hian thisenah emaw ruhroah emaw lymphoma a awm leh awm loh a enfiah thin.
• Blood chemistry study: Hei hian i electrolyte level, liver leh kidney hnathawh dan a teh a, taksa peng leh tissue a chhiat huna thisena thil awmkhawmte a zawng thin.
• Erythrocyte sedimentation rate (ESR): Hei hian taksaa inflammation a teh thin. He value hi Hodgkin lymphoma-ah hian a sang thei hle.
• Lactate dehydrogenase (LDH) test: Hei hian cell a chhiat huna protein chhuak chu a teh a ni. LDH level hi a chang chuan lymphoma nen a sang chho thin.
• Viral test: Heng test te hian Hodgkin lymphoma nena inzawm thei, HIV , hepatitis B , leh hepatitis C te ang chi virus infection awm mek emaw, tun hmaa emaw a hmuchhuak thei a, a result hian i doctor chu i enkawl dan tur ruahmanna siam turin a pui thei a ni.

Imaging test te pawh a awm

Scan hian i taksa chhunga cancer chhinchhiahna a zawng thei a ni. Scan i mamawh chi chu cancer awmna hmun leh naupai leh naupai lohah a innghat ang. (X-ray hmanga scan hian nausen tan a tichhe thei a ni.) Heng test-ah hian:

• Chest X-ray neih a ni
• CT scan (CT scan - Computed tomography scan) hmanga tih a ni.
• PET scan (Positron emission tomography hmanga enfiah) hmanga enfiah a ni.
• MRI scan (Magnetic resonance imaging scan) (naupai laiin a him) .
• Ultrasound scan (naupai laiin a him) .

Biopsy tih a ni

Doctor te chuan Hodgkin lymphoma hi lymph node biopsy hmangin an hmuchhuak tlangpui thin . Hetiang tihnaah hian doctor chuan lymph node zawng zawng emaw, a then emaw a la chhuak vek a ni. Chumi hnuah pathologist chuan microscope hmangin tissue chu a enfiah a , Reed-Sternberg cells a awm leh awm loh a enfiah a, chu chu a hmaa kan sawi tawh kha a ni. (Hetiang Reed-Sternberg cell awm hian Hodgkin lymphoma i nei tihna a ni a, non-Hodgkin lymphoma i nei tihna a ni.)

A châng chuan, Hodgkin lymphoma hi hmun dang aṭanga lak chhuah tissue biopsy result aṭanga hriat theih a ni bawk a, chu chu lung, liver, spleen emaw bone marrow emaw a ni.

Hodgkin Lymphoma hi eng stage nge ni?

I doctor-in Hodgkin lymphoma a vei tih a hriat hnuah i test result chuan natna stage a hril ang. I cancer stage hriat hian doctor-te chu cancer chu eng chen nge a darh tawh tih te, a darh chak dan tur te, leh eng enkawlna nge i tana tha ber tih te hriat theih nan a pui a ni. Hodgkin lymphoma stage hrang hrangte chu hetiang hi a ni:

• Stage I: Cancer cells te hi lymph node region pakhatah emaw, lymphatic system chhunga organ pakhatah emaw (e.g., thymus, spleen, bone marrow) an awm a. A nih loh leh lymphoma hi lymphatic system pawn lama taksa peng pakhat hmun khatah a awm a ni.
• Stage II: I diaphragmA sir khatah lymph node group hnih emaw a aia tam emaw-ah cancer cell a awm a (diaphragm bula lymph node dang pawh a nghawng thei bawk).
• Stage III: Diaphragm sir lehlamah lymph node-ah lymphoma cell a awm a, a nih loh leh diaphragm chung lam lymph node-ah leh spleen-ah cancer cell a awm bawk.
• Stage IV: Lymphoma hi lymphatic system pawn lama taksa peng pakhat tal (e.g., liver, lungs, bone marrow)-ah a awm a.

Doctor-te chuan Hodgkin lymphoma hi enkawlnaah a chhân lêt ṭhat leh ṭhat loh leh symptom-free (remission) a la awm reng leh awm loh a zirin, "favorable" leh "unfavorable" tih thumal hi an hmang bawk.

Hodgkin Lymphoma hi engtin nge enkawl a nih?

Doctor-te chuan Hodgkin lymphoma enkawl dan hrang hrang an hmang a, chu chu cancer stage a zirin a ni. Heng enkawlnate hian cancer cell te chu a that emaw, a inthen darh emaw a titawp emaw a ni. Enkawlna kawng hrang hrangte chu:

• Chemotherapy: Hei hi Hodgkin lymphoma enkawlna atana hman tlanglawn ber a ni. Damdawi pakhat emaw a aia tam emaw hmangin cancer cell te chu a that emaw, an pung zel tur a titawp emaw a ni. Doctor-te chuan chemotherapy chi khat emaw, chemotherapy chi hrang hrang inzawmkhawm emaw an hmang thei a ni.
• Radiation therapy: He enkawlna hian high-energy beams of energy hmangin cancer cells te chu lymph node natna vei emaw, cancer darh nana hmunah emaw a that thin. Hodgkin lymphoma hmasa ber enkawlnaah pawh chemotherapy nen hman a ni bawk.
• Immunotherapy: He enkawlna hian i taksain cancer cell a hriat theih nan leh a tihchhiat theih nan a taksa hriselna a tichak a ni. Checkpoint inhibitor hi Hodgkin lymphoma enkawlna atana immunotherapy enkawlna pawimawh tak a ni.
• Targeted therapy: Targeted therapy hian damdawi emaw thil dang emaw hmangin cancer cell chauh a bei thin. Entîr nân, damdawi pakhat, antibody-drug conjugates . Hetah hian lab-a siam antibodies te chu chemotherapy damdawi-ah an inzawm a, chu chuan cancer cell te chu a zawng chhuak a, a tichhia a ni.
• Chemotherapy with stem cell transplantation: He enkawlna hi Hodgkin lymphoma chu remission-a a kal hnua a lo lang leh emaw, enkawlna a dawng lo emaw a nih chuan hman a ni fo thin. Chutiang a nih chuan a tir lama chemotherapy pek i nihna aiin chemotherapy chi danglam tak pek i ni ang. Cancer hian a chhang let a nih chuan i doctor chuan stem cell transplant a ti ang.

Enkawlna hrang hrangte side effects

Treatment tin hian side effect hrang hrang a nei thei. Entirnan, Chemotherapy hmang hian sam a tlakchhiat a, nausen a thlen thei bawk. Radiation therapy hmanga enkawlna hmunah ni zung a kang thei a ni. Immunotherapy hian side effects a nei thei a, chu chu vun vun rawng, luak chhuak, leh lungphu inflammation te a ni thei a, chu chuan thawk harsatna leh khuh a thlen thei a ni.

Enkawl i tan hmain i doctor hnenah side effect awm thei te zawt hmasa phawt ang che. Ani chuan a side effect awm thei leh enkawlna hlawkna te tehna atan a pui ang che.

Hodgkin Lymphoma hi eng nge a nih?

Doctor-te chuan Hodgkin lymphoma hi cancer enkawl theih leh a tam zawkah chuan tihdam theih niin an ngai. I thlirna chu natna stage leh thil dang dangah a innghat a ni. Hemi chungchang hi i doctor chuan a sawipui thei che a ni. Mahse, a chang chuan enkawlna a hlawhtling lo va, cancer chu a lo let leh thei a ni. Heng classification te hian i prognosis a nghawng dan hi i doctor zawt rawh.

Hodgkin Lymphoma vei damchhuah zat hi engzat nge ni?

Doctor-te’n enkawlna thar leh ṭha zawk an siam chhuah avangin Hodgkin lymphoma vei damchhuah zat pawh a ṭha chho zel a ni. US National Cancer Institute chhinchhiah danin kum 2014 leh 2020 inkar chhunga Hodgkin lymphoma vei hmuhchhuah zinga 88% chu enkawl a nih hnu kum nga chhungin an la dam a ni.

Cancer stage a zirin damchhuah zat a inang lo. He statistics ang chiah hian natna hmasa ber vei hmuhchhuah zinga 92% leh 95% inkar chu an hmuhchhuah atanga kum nga hnuah pawh an la dam a ni. Natna hnuhnung zawk vei hmuhchhuah zinga 81% leh 87% inkar chu an hmuhchhuah atanga kum nga hnuah pawh an la dam a ni. Hei hian natna hi hriat hmasak a pawimawh zia a tilang chiang hle a ni lawm ni?

Engtin nge ka in enkawl ang?

I Hodgkin lymphoma symptoms chu enkawlna nen a bo dawn tih i hriat chuan i rilru a hahdam mai thei. Mahse, chu dinhmun chu a lo let leh ang tih i hlau emaw, i hlau emaw pawh a ni thei. Heng rawtnate hian Hodgkin lymphoma natna vei hi tlem a awlsam zawk nan a pui thei a ni:

• Chawlh hahdam: Cancer leh cancer enkawlna pahnih hian hahna nasa tak a thlen thei. I rilru leh taksa chu an mamawh chawlh hahdamna pe rawh.
• Ei leh in inthlau tak, ei tur tha tak ei: I ei leh in leh Hodgkin lymphoma hi inzawmna chiang tak a awm lo. Mahse, ei tha ei hian i taksa hriselna a humhim thei a, virus kai theihna a ti tlem thei bawk. Chaw ei \ha chungchang hriat belh i duh chuan dietitian nen inbia ang che.
• Stress enkawl: Hodgkin lymphoma hi enkawl hnuah a lo lang leh thei. Natna lo awm leh tûra lungkhamna chu a buaithlâk thei a ni. I dinhmun a lo let leh ang tih i hlau reng a nih chuan i doctor nen inbia ang che. I dinhmun hriat tur tha ber a ni. Beisei tûr hriatna chuan i lungkhamna a tihziaawm thei a ni.
• Exercise: Exercise neih fo hian i immune system a pui mai bakah stress control nan a pui bawk. Cancer enkawlna avanga side effect awm fo, hahna dona atana hmanraw tha tak a ni bawk.

A pawimawh ber chu Hodgkin lymphoma i vei tih hmuhchhuah a nih chuan i nun chu a famkimin i hmang thei lo tihna a ni lo. Side effects hmachhawn tur chuan inthlak danglamna engemaw zat i siam a ngai dawn a ni. Cancer natna nei lo aiin i doctor i pan fo a ngai dawn a ni. Mahse, tlem tlem chuan i tana tha tur routine leh pace i hmu ang.

Engtikah nge ka doctor ka hmuh ang?

Hodgkin lymphoma enkawl i nih chuan enkawl chung pawha i dinhmun a chhe zual zel tih chhinchhiahna i hmuh chuan doctor pan rawh (e.g., lump thar, khawsik). Enkawlna i zawh hnuah chuan i hriselna zawng zawng enfiah tur leh natna lo lang leh leh awm loh enfiah turin follow -up appointment i nei ang.

Engtikah nge emergency room-ah ka kal ang?

I damdawi pek i ei hnua a reh lo, i beisei aia na zawk, a rei zawk emaw, a rei zawk emaw a nih chuan emergency room-ah kal rawh. I doctor leh medical team te chuan hemi chungchang hi an sawipui ang che.

Doctor hnenah eng zawhna nge ka zawh ang?

Hodgkin lymphoma hmuhchhuah leh enkawl chhung hian zawhna tam tak i nei thei. I doctor zawh tur zawhna thenkhat chu hetiang hi a ni:

• Hodgkin lymphoma hi eng chi nge ka neih?
• Ka natna hi eng stage nge ni?
• Eng enkawlna nge i rawt?
• Enkawlna atang hian eng side effect nge beisei tur?
• Ka dinhmun hi i tidam thei ang em?
• Cancer lo kir leh theihna chance chu engzat nge ni?

Hodgkin Lymphoma leh Non-Hodgkin Lymphoma hi eng nge an danglamna?

Hodgkin lymphoma leh non-Hodgkin lymphoma te hi i lymphocyte cells tichhe thei cancer an ni vek a, mahse an pahnih inkarah hian danglamna tlemte a awm.

Doctor-te chuan Hodgkin lymphoma hi cancer chi hrang hrang tihdam theih ber pakhatah an ngai a. Enkawlna thar hian Hodgkin lymphoma symptoms a ti bo thei a, natna hi a tidam vek mai thei.

Mahse, i thlirna chu Hodgkin lymphoma chi leh cancer stage-ah a innghat a ni. Zirna hrang hrangah chuan Hodgkin lymphoma, early-stage Hodgkin lymphoma vei enkawl mek zinga 90% aia tam chu an natna hmuhchhuah atanga kum nga hnuah pawh an la dam tih hmuhchhuah a ni. Phên dangin sawi ila, a hriat chhuah hma chuan a ṭha zawk.

I taksaa inthlak danglamna, lymph node hring, khawsik chhunzawm zel, leh hahna te chu hre reng ang che. Heng symptoms i neih hian Hodgkin lymphoma i nei tihna a ni lo a, mahse test neih a tha. He natna chungchang sawi dawn chuan a hmaa hriatchhuah chuan cancer nei lova nun theihna a tipung thei a ni.

A tawp berah chuan take-home message:

Hodgkin Lymphoma tih hming i hriat hian hlauthawng tih hi thil pangngai tak a ni. Mahse, hei hi cancer a ni tih hre reng ang che, a tam zawk chu tihdam theih a ni. A pawimawh ber chu natna lan chhuah dan i hriat veleh damdawi lam thurawn lak hi a ni. A bik takin, i kawr, i kekawrte, i kekawrteah natna nei lo, i hah reng, chhan theih loh khawpa khawsik, zan lama thawk hah lutuk, leh i taksa rihna tlahniam ang chi i neih chuan doctor i pan ngei tur a ni.

Hriatchhuah hmasak leh enkawl dan dik a nih chuan mi tam tak chu Hodgkin lymphoma atanga an dam kim thei tawh a, nun pangngaiin an nung thei tawh a ni. Chuvangin, beiseina chu bansan ngai suh. I tana thuchah pawimawh ber ka neih chu nangmah emaw, i hriat mi emaw hian heng symptoms hi an neih chuan a rang thei ang bera doctor rawn la rawh.

` Hodgkin lymphoma, cancer, lymph nodes, a lan chhuah dan, enkawl dan, B cells, Reed-Sternberg cells